KEGG   Myotis brandtii (Brandt's bat): 102241454
Entry
102241454         CDS       T02920                                 
Symbol
ARAF
Name
(RefSeq) A-Raf proto-oncogene, serine/threonine kinase
  KO
K08845  A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
Organism
myb  Myotis brandtii (Brandt's bat)
Pathway
myb01521  EGFR tyrosine kinase inhibitor resistance
myb01522  Endocrine resistance
myb04010  MAPK signaling pathway
myb04012  ErbB signaling pathway
myb04068  FoxO signaling pathway
myb04270  Vascular smooth muscle contraction
myb04650  Natural killer cell mediated cytotoxicity
myb04720  Long-term potentiation
myb04726  Serotonergic synapse
myb04730  Long-term depression
myb04810  Regulation of actin cytoskeleton
myb04910  Insulin signaling pathway
myb04914  Progesterone-mediated oocyte maturation
myb04928  Parathyroid hormone synthesis, secretion and action
myb05010  Alzheimer disease
myb05022  Pathways of neurodegeneration - multiple diseases
myb05034  Alcoholism
myb05160  Hepatitis C
myb05161  Hepatitis B
myb05200  Pathways in cancer
myb05205  Proteoglycans in cancer
myb05208  Chemical carcinogenesis - reactive oxygen species
myb05210  Colorectal cancer
myb05211  Renal cell carcinoma
myb05212  Pancreatic cancer
myb05213  Endometrial cancer
myb05214  Glioma
myb05215  Prostate cancer
myb05218  Melanoma
myb05219  Bladder cancer
myb05220  Chronic myeloid leukemia
myb05221  Acute myeloid leukemia
myb05223  Non-small cell lung cancer
myb05224  Breast cancer
myb05225  Hepatocellular carcinoma
myb05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:myb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102241454 (ARAF)
   04012 ErbB signaling pathway
    102241454 (ARAF)
   04068 FoxO signaling pathway
    102241454 (ARAF)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102241454 (ARAF)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    102241454 (ARAF)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102241454 (ARAF)
   04914 Progesterone-mediated oocyte maturation
    102241454 (ARAF)
   04928 Parathyroid hormone synthesis, secretion and action
    102241454 (ARAF)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    102241454 (ARAF)
  09156 Nervous system
   04726 Serotonergic synapse
    102241454 (ARAF)
   04720 Long-term potentiation
    102241454 (ARAF)
   04730 Long-term depression
    102241454 (ARAF)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102241454 (ARAF)
   05205 Proteoglycans in cancer
    102241454 (ARAF)
   05208 Chemical carcinogenesis - reactive oxygen species
    102241454 (ARAF)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102241454 (ARAF)
   05212 Pancreatic cancer
    102241454 (ARAF)
   05225 Hepatocellular carcinoma
    102241454 (ARAF)
   05226 Gastric cancer
    102241454 (ARAF)
   05214 Glioma
    102241454 (ARAF)
   05221 Acute myeloid leukemia
    102241454 (ARAF)
   05220 Chronic myeloid leukemia
    102241454 (ARAF)
   05218 Melanoma
    102241454 (ARAF)
   05211 Renal cell carcinoma
    102241454 (ARAF)
   05219 Bladder cancer
    102241454 (ARAF)
   05215 Prostate cancer
    102241454 (ARAF)
   05213 Endometrial cancer
    102241454 (ARAF)
   05224 Breast cancer
    102241454 (ARAF)
   05223 Non-small cell lung cancer
    102241454 (ARAF)
  09172 Infectious disease: viral
   05161 Hepatitis B
    102241454 (ARAF)
   05160 Hepatitis C
    102241454 (ARAF)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102241454 (ARAF)
   05022 Pathways of neurodegeneration - multiple diseases
    102241454 (ARAF)
  09165 Substance dependence
   05034 Alcoholism
    102241454 (ARAF)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102241454 (ARAF)
   01522 Endocrine resistance
    102241454 (ARAF)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:myb01001]
    102241454 (ARAF)
Enzymes [BR:myb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     102241454 (ARAF)
Protein kinases [BR:myb01001]
 Serine/threonine kinases: TKL group
  RAF family [OT]
   102241454 (ARAF)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase RBD C1_1 Kinase-like ABC1 Pkinase_fungal zf-RING-like TUG-UBL1 Kdo
Other DBs
NCBI-GeneID: 102241454
NCBI-ProteinID: XP_005871073
LinkDB
Position
Un
AA seq 611 aa
MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
VYRLIEGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNCRQYYHSIQDLSGGYRQHEAPSNRPLNEPL
TPQGSSLSPGSSSSQHRDPEHFPFPATANAPLQRIRSTSTPNVHMVSTTTPLDSSLIQLA
AQSFNAEAAGSRGGSDGAPRGSPSPASVSSGRKSPHSKSPSEQRERKSLADDKKKVKNLG
YRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVAQPTAEQAQAFKNEM
QVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQ
GMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA
EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIS
SNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELP
ACLLSAARLVP
NT seq 1836 nt   +upstreamnt  +downstreamnt
atggagccaccacggggcccccctgccaacggggccgagccgtcccgggcagtgggcact
gtcaaagtgtacctgcccaacaagcaacgcacagtggtgactgtccgggatggcatgagt
gtctacgactctctagacaaggctctcaaggtgcggggtctcaatcaggattgttgcgtg
gtctaccggctcatcgaagggcgaaagacagtcactgcctgggacacagccattgccccc
ctggatggcgaggagctcattgttgaggtccttgaagatgtcccactgactatgcacaat
tttgtacggaagacgttcttcagcctggcgttctgtgacttctgccttaagtttctgttc
catggcttccgctgccaaacctgtggctacaagttccaccagcattgttcctctaaggtc
cccacagtctgtgttgacatgagtaccaactgccgacagtactaccacagtatccaggat
ttgtccggaggctacagacagcatgaggctccctccaaccgtcctctgaatgagccacta
acccctcagggttccagtctctcccctggcagctccagctcccagcaccgagaccctgaa
cacttcccctttcctgccacggccaacgcccccctgcagcgcatccgctccacgtctact
cccaacgtccatatggtcagcaccacaacccccctggactccagtctcatccagctcgct
gcccagagtttcaatgctgaagctgctggtagtagaggtggcagtgatggagcgccccgg
gggagccccagcccagctagtgtgtcctcggggaggaagtccccacattccaagtccccc
tcagaacagcgggagaggaagtccttggctgatgacaagaagaaagtgaagaatctgggg
taccgggactcgggctattactgggaggtgccacccagtgaggtgcagctgctgaagagg
atcgggacgggctcgtttggcaccgtgtttcgcgggcggtggcatggcgatgtggctgtg
aaggtgctcaaggtggcccaacccacagctgagcaggcccaggccttcaagaacgagatg
caggtgctcaggaagacacgtcatgtcaacatcttgctgttcatgggcttcatgacccgg
ccggggttcgccatcatcacacagtggtgcgagggctccagcctctaccaccacctgcat
gtggccgacacacgcttcgacatggtccaactcattgatgtggcccggcagactgcccag
ggcatggactacctccatgccaagaacatcatccaccgggatctcaagtctaacaacatc
ttcctgcatgaggggctcacagtgaagatcggcgacttcggcctggccacggtgaagaca
agatggagcggggctcagcccttggagcagccctcaggctctgtgctgtggatggcggct
gaggtgatccgtatgcaggacccgaacccctacagcttccagtcggatgtctacgcctat
ggggttgtgctctacgagctcatgaccggctccttgccttatagccacattggcagccgt
gaccagattatctttatggtgggccgcggctatctgtccccggacctcagcaaaatctcc
agcaactgccccaaggccatgcggcgcctgctgtctgattgcctcaagtttcagcgagag
gagcggcccctcttcccccagatcctggccaccattgagctgctgcagcggtcactcccc
aagattgagcggagtgcctccgaaccctccttgcatcgcacccaggctgatgagttgccc
gcctgcctactcagcgcagcccgccttgtgccttag

DBGET integrated database retrieval system