Myotis brandtii (Brandt's bat): 102244385 Help Entry 102244385         CDS       T02920                                  Symbol TYK2 Name (RefSeq) tyrosine kinase 2   KO K11219   non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2] Organism myb  Myotis brandtii (Brandt's bat) Pathway myb04217   Necroptosis myb04380   Osteoclast differentiation myb04620   Toll-like receptor signaling pathway myb04621   NOD-like receptor signaling pathway myb04630   JAK-STAT signaling pathway myb04658   Th1 and Th2 cell differentiation myb04659   Th17 cell differentiation myb05145   Toxoplasmosis myb05160   Hepatitis C myb05161   Hepatitis B myb05162   Measles myb05164   Influenza A myb05165   Human papillomavirus infection myb05167   Kaposi sarcoma-associated herpesvirus infection myb05168   Herpes simplex virus 1 infection myb05169   Epstein-Barr virus infection myb05171   Coronavirus disease - COVID-19 Brite KEGG Orthology (KO) [BR:myb00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     102244385 (TYK2)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     102244385 (TYK2)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     102244385 (TYK2)    04621 NOD-like receptor signaling pathway     102244385 (TYK2)    04658 Th1 and Th2 cell differentiation     102244385 (TYK2)    04659 Th17 cell differentiation     102244385 (TYK2)   09158 Development and regeneration    04380 Osteoclast differentiation     102244385 (TYK2)  09160 Human Diseases   09172 Infectious disease: viral    05161 Hepatitis B     102244385 (TYK2)    05160 Hepatitis C     102244385 (TYK2)    05171 Coronavirus disease - COVID-19     102244385 (TYK2)    05164 Influenza A     102244385 (TYK2)    05162 Measles     102244385 (TYK2)    05168 Herpes simplex virus 1 infection     102244385 (TYK2)    05167 Kaposi sarcoma-associated herpesvirus infection     102244385 (TYK2)    05169 Epstein-Barr virus infection     102244385 (TYK2)    05165 Human papillomavirus infection     102244385 (TYK2)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     102244385 (TYK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:myb01001]     102244385 (TYK2) Enzymes [BR:myb01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102244385 (TYK2) Protein kinases [BR:myb01001]  Non-receptor tyrosine kinases   JAK family [OT]    102244385 (TYK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 SH2_1 Kdo Kinase-like FERM_C_FAK1 ABC1 RIO1 Motif Other DBs NCBI-GeneID:  102244385 NCBI-ProteinID:  XP_005859231 LinkDB All DBs Position Un AA seq 1188 aa AA seqDB search MPLCHGGATAGTSKPDGDETQLTAITGGLKVFLHWAGPGSREPWVTFSEATLTAEEVCIH IAHKVGITPPCFNLFALFDAQAQVWLPPNHIFEVSRDTNLTLHFRMRFYFRNWHGTNPQE PAVYRCRPPGAEASSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHF KNESLGMAFLHLCHLALCRGVPLEKVAKKTSFKDCIPRSFRQQIQQYNAFTRLRLRIIFR KFLHAFQPDSLSQHIVMVKYLATLERLAPRFGTERVPVCHLELLAQAEGEPCYIQDSAQA PGDPKPKSAVEPPTHEVLVTGNGGIQWRPIQTEVLGFQGPGGGDGGSSRNPHAGFSGKKA KAQQQGGQPVDRPRDAPWAYFCDFRDITHVVLRGRHVSIHCQDKRLELTLPSPAIALSLV SLVDGYFRLTADSNHYLCHEVAPPRLVMSIQDGVHGPLLDPFVLAKMQREDGLYLIHWST SHFNRLILTVAQQDQAPGTPRLRLWKFPIELCEGTFRLQSWDRSFPSVRELRAALQGCSL RAGDHCFSLRHCCLPQPGEISNLIIMRGPQASARSLNLSQLSFHRVCQDDLTQLSHLGQG TRTNVYEGLLRVGGGGPEEDKAYVGDPTLPSGGHGQELRVVLKVLDTSHHDIALAFYETA SLMSQVSHVHLTFVHGVCVHGSQNIMVTEYVEHGPLDVWLRRERGRVPVAWKVAVAQQLA SALSYLEDKRLAHGNVCGRNILLARLGLAEGTSPFIKLSDPGMGLGALSREERVERIPWM APECLFGGANSLSTAADKWGFGATLLEICFDGEAPLQDRSPAEKEYFYQKQHQLPEPSCP ELATLTSQCLTYEPAQRPSFRTILRDLTHLQPQNLVEILCVNPTSPASDPTVFHKRYLKK IRDLGEGHFGKVSLYCYDPTNEGTGEMVAVKALKADCGPQLRTSWRREIDILRTLYHEHI VKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHHVGLAQLLLFAQQICEGMAYLHTQHY VHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHDYYRVREDGDSPVFWYAPECLKECKFY YASDVWSFGVTMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPRPEK CPHEIYVLMKNCWEAEASFRPTFQNLIPILKTAHEKYQGQAPSVFSVG NT seq 3567 nt NT seq  +upstreamnt  +downstreamnt atgcctctgtgccatgggggggccaccgccgggaccagcaagcccgatggggacgaaact cagctcacagccatcacaggaggcctgaaggtgttcctgcactgggctggccctggcagc agggagccctgggttactttcagcgaggccacactgaccgcagaggaggtctgcattcac atcgcacacaaagtcggcatcactccaccctgtttcaatctctttgccctctttgatgcc caggcccaggtctggctgcccccaaaccacatttttgaggtctccagagacacaaacttg acgctgcacttccgcatgaggttttatttccgcaactggcatggcacaaatcctcaggag ccagctgtgtaccgctgcaggcccccaggggccgaggcttcgtcagaacaggcagagcag ggggtgcaactcctggacccagcctcctttgagtacctctttgagcagggcaagcacgag tttgtgaatgatgtggcatcgctgtgggagctgtcgagtgaggaggagatccaccacttt aagaacgagagcctgggcatggcctttctgcacctctgtcacctggctctctgccgcggt gttcccctggagaaggtggccaagaagaccagcttcaaggactgtatcccgcgctctttc cggcaacagatccagcagtacaatgcgttcacacggctacgcctgcggatcatcttccgc aagttcctgcacgccttccagccggacagcctttcccagcacatagtcatggtcaagtac ctggccacactcgagcggctggcaccccgcttcggcacggagcgtgtgcctgtgtgccac ctggagctgctagcccaggccgagggggagccctgctatatccaggacagtgcacaggcc cctggagatcccaagcccaagtctgcggtcgaaccgcccacccacgaggtgctggtgacc ggcaatggcggcatccagtggcggccaatacagacagaggtgctgggtttccagggtccc ggtggtggtgacggtggcagcagcaggaatcctcatgctggcttctctgggaagaaagcc aaggcccagcagcagggcggccagcccgtggacaggccgcgggatgcgccgtgggcctac ttctgtgacttccgggacatcacccatgtggtgctgagaggacgccacgtcagcatccac tgtcaggacaagcgcctggagctgaccctgccttccccggccatcgccctgtccttggtg tcactggtggacggctatttccgcctgacggccgactcgaaccactacctgtgccacgag gtggctcctccacggctggtgatgagcatccaggacggtgtccacggacccctgctggat ccatttgtgctggccaagatgcagcgcgaggatggcctctaccttatccactggagcacc agccacttcaaccgcctcatcctcacggtggcccagcaggaccaggcacccggcacgccg cgtttgcgcctgtggaagttccccattgagctgtgtgagggcaccttccggctgcagagc tgggaccggtccttccccagcgtgcgggagctgcgggctgccctgcagggctgctcactg cgggccggtgaccactgcttctccctgcgccactgctgcctgccgcagccaggagagatc tccaacctcatcatcatgcgggggcctcaagccagcgcccggtctctcaacctcagccag ctcagcttccaccgggtctgccaggatgacctcacccagctgtcccacttgggccagggc acgaggaccaatgtgtatgagggcctcttgagagttgggggcggaggccctgaggaggac aaagcatatgttggggaccccaccttgcccagcgggggccatgggcaggagctgcgagtg gtgctgaaggtgttagacactagtcaccatgacatcgccctggctttctacgagacggcc agcctcatgagccaggtgtcccacgtgcacctgaccttcgtccatggtgtctgcgtgcac ggctctcaaaatatcatggtgacagagtacgtggagcatggacccctggacgtgtggctg cggcgggagaggggccgtgtgcccgtggcctggaaggtggcagtggcccagcagctggcc agtgccctcagctacctggaggacaagcgcctggctcatggtaacgtgtgtggccggaac atcctgctggcacgtctagggctggcggagggcaccagcccattcatcaaactgagcgac cctggcatgggcctgggcgccctctccagggaggagcgggtagagcggatcccctggatg gcccccgagtgcctgtttggtggggccaacagcctcagcaccgccgctgacaagtggggc ttcggtgccaccctcctggagatctgcttcgatggggaggcccccctgcaggaccgcagc ccagccgagaaggagtacttctaccagaagcagcaccagctgcctgaaccctcatgcccg gagctagccacgctcaccagccagtgcctgacctatgagccggctcagcggccttccttc cgcaccatccttcgtgacctcactcaccttcagccccaaaatcttgttgaaatcttgtgt gtgaatccaacctcgccagcgtcagaccccacagttttccacaagcgctacttgaagaag atccgggatctgggtgagggtcactttggcaaggtcagcctgtactgctatgacccgacc aatgaaggtaccggcgagatggtggccgtgaaggctctcaaggcggactgcggccctcag cttcgcaccagctggaggcgggagatcgacatcctgcgcacgctctaccacgagcacatc gtcaagtacaagggctgctgtgaggaccaaggcgagaaatcggtccagcttgtcatggag tacgtgcctctgggcagcctccgagactacctgccccggcaccacgtagggctggcccag ctgctgctgttcgcccagcagatctgcgagggcatggcctacctgcacacccagcactat gtccaccgagacctggctgcccgcaacgtgctgctggacaacgacaggctggtcaagatc ggggactttggcctcgccaaggccgtgcccgaaggccacgactactaccgcgtgcgcgag gatggggacagccccgtgttctggtacgctcctgagtgtctgaaggagtgtaagttctac tatgcgtccgatgtctggtcctttggagtcaccatgtatgaactgctgacctactgtgac tccagccaaagccccccctcgaaattcatcgagctcataggcctcacccaggggcagatg accgtactgaggctcactgagctgctggaacgaggggagaggctgccacggccagagaaa tgtccccatgagatctatgtcctcatgaagaactgctgggaggcagaggcctcatttcgc ccaaccttccagaacctcatacccatcctgaaaacggcccacgagaagtaccagggccag gccccctcggtgttcagtgtcggctaa

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