Myotis brandtii (Brandt's bat): 102247996 Help Entry 102247996         CDS       T02920                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism myb  Myotis brandtii (Brandt's bat) Pathway myb00230   Purine metabolism myb01100   Metabolic pathways myb01522   Endocrine resistance myb04015   Rap1 signaling pathway myb04020   Calcium signaling pathway myb04022   cGMP-PKG signaling pathway myb04024   cAMP signaling pathway myb04062   Chemokine signaling pathway myb04072   Phospholipase D signaling pathway myb04081   Hormone signaling myb04082   Neuroactive ligand signaling myb04114   Oocyte meiosis myb04211   Longevity regulating pathway myb04213   Longevity regulating pathway - multiple species myb04261   Adrenergic signaling in cardiomyocytes myb04270   Vascular smooth muscle contraction myb04371   Apelin signaling pathway myb04540   Gap junction myb04611   Platelet activation myb04713   Circadian entrainment myb04714   Thermogenesis myb04723   Retrograde endocannabinoid signaling myb04724   Glutamatergic synapse myb04725   Cholinergic synapse myb04727   GABAergic synapse myb04742   Taste transduction myb04750   Inflammatory mediator regulation of TRP channels myb04911   Insulin secretion myb04912   GnRH signaling pathway myb04913   Ovarian steroidogenesis myb04914   Progesterone-mediated oocyte maturation myb04915   Estrogen signaling pathway myb04916   Melanogenesis myb04918   Thyroid hormone synthesis myb04921   Oxytocin signaling pathway myb04923   Regulation of lipolysis in adipocytes myb04925   Aldosterone synthesis and secretion myb04926   Relaxin signaling pathway myb04927   Cortisol synthesis and secretion myb04928   Parathyroid hormone synthesis, secretion and action myb04934   Cushing syndrome myb04935   Growth hormone synthesis, secretion and action myb04970   Salivary secretion myb04971   Gastric acid secretion myb04972   Pancreatic secretion myb04976   Bile secretion myb05032   Morphine addiction myb05163   Human cytomegalovirus infection myb05166   Human T-cell leukemia virus 1 infection myb05200   Pathways in cancer myb05207   Chemical carcinogenesis - receptor activation myb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:myb00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102247996 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102247996 (ADCY4)    04371 Apelin signaling pathway     102247996 (ADCY4)    04020 Calcium signaling pathway     102247996 (ADCY4)    04072 Phospholipase D signaling pathway     102247996 (ADCY4)    04024 cAMP signaling pathway     102247996 (ADCY4)    04022 cGMP-PKG signaling pathway     102247996 (ADCY4)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102247996 (ADCY4)    04081 Hormone signaling     102247996 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102247996 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     102247996 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102247996 (ADCY4)    04062 Chemokine signaling pathway     102247996 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     102247996 (ADCY4)    04923 Regulation of lipolysis in adipocytes     102247996 (ADCY4)    04912 GnRH signaling pathway     102247996 (ADCY4)    04913 Ovarian steroidogenesis     102247996 (ADCY4)    04915 Estrogen signaling pathway     102247996 (ADCY4)    04914 Progesterone-mediated oocyte maturation     102247996 (ADCY4)    04921 Oxytocin signaling pathway     102247996 (ADCY4)    04926 Relaxin signaling pathway     102247996 (ADCY4)    04935 Growth hormone synthesis, secretion and action     102247996 (ADCY4)    04918 Thyroid hormone synthesis     102247996 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     102247996 (ADCY4)    04916 Melanogenesis     102247996 (ADCY4)    04925 Aldosterone synthesis and secretion     102247996 (ADCY4)    04927 Cortisol synthesis and secretion     102247996 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102247996 (ADCY4)    04270 Vascular smooth muscle contraction     102247996 (ADCY4)   09154 Digestive system    04970 Salivary secretion     102247996 (ADCY4)    04971 Gastric acid secretion     102247996 (ADCY4)    04972 Pancreatic secretion     102247996 (ADCY4)    04976 Bile secretion     102247996 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     102247996 (ADCY4)    04727 GABAergic synapse     102247996 (ADCY4)    04725 Cholinergic synapse     102247996 (ADCY4)    04723 Retrograde endocannabinoid signaling     102247996 (ADCY4)   09157 Sensory system    04742 Taste transduction     102247996 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     102247996 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     102247996 (ADCY4)    04213 Longevity regulating pathway - multiple species     102247996 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     102247996 (ADCY4)    04714 Thermogenesis     102247996 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102247996 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     102247996 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102247996 (ADCY4)    05163 Human cytomegalovirus infection     102247996 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     102247996 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102247996 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102247996 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102247996 (ADCY4) Enzymes [BR:myb01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102247996 (ADCY4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 Motif Other DBs NCBI-GeneID:  102247996 NCBI-ProteinID:  XP_014389772 LinkDB All DBs Position Un AA seq 1102 aa AA seqDB search MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLCALPYFVLGFETLFRTGLRSCP FFLFLDELPKPHTRPSPQELAADPGFLTTVLCALGGFSLLLGLASCEQRLQRWTRPLSGL VWAALLALGHGFLFTGGVVSAWDQVSFFLFVIFTTYAMLPLGMRDATAAGLTSSLSHLLV LGLYLGPQRDSRPALLPQLAANAVLFLCGNVAGAYHKALMERALRATFREALSSLHSRRR LDTEKKHQEHLLLSILPAYLAREMKAEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVL YADIVGFTRLASECSPKELVLMLNELFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLP DHAINCVRMGLDMCRAIRKLRAATGVDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTL ANHMEAGGVPGRVHITGATLALLAGAYAVEDAAIEHRDPYLRELGEPTYLVIDPRAEEED EKGTAGGLLSSLEGPKMRPSLLMTRYLESWGAAKPFAHLSHVESPVSTSTPLPEKALASF SPQWSLDRSRTPRGLDDEMDTGDAKFFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKE YRLSALPAFKYYAACTFLVFLSNFIIQMLVTNRPPALAITYSITFLLFFLLLFVCFSEHL TRCVLKGPKMLHWLPSLSGLVATRPGLRIALGSATILLIFAMAITSLFFLPAASNCPFRA TNVSSMAFNLSWELPGSLPLISIPYSMHCCVLGFLSCSLFLHMSFELKLLLLLLWLVASC CLFLHSHAWLSDCLVARLYLGSLDSRPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCR LDFLWKKKLRQEREETETMENLTRLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVL FASVPDFKEFYSESNINHEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAAT GLNATSGQDAQQDAERSCSHLGTMVEFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAG VIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETARALQSLGYTCYSRGVIKVKGKG QLCTYFLNTDLIRVGPPSAALG NT seq 3309 nt NT seq  +upstreamnt  +downstreamnt atggcccgactcttcagtccccggccgccacccagcgaagacctcttctatgagacctac tacagcctgagccaacagtacccgctgctgctgctgctgctggtgatcgtgctctgtgcc ctgccttattttgtacttgggtttgagacacttttcagaactggcctgaggagctgtcca ttctttctcttcctggacgagctccccaaaccccacacgcgcccctccccacaggagctg gccgcagacccgggcttcctgaccacagtgctgtgcgcgctgggcggcttctcgctgctg ctgggcctggcttcctgcgagcagcggctccagcgctggacgcgtccgctgtcgggcctc gtgtgggcagcgctgcttgcgttaggccatggcttcctattcactgggggcgtggtgagc gcctgggaccaggtgtcctttttcctctttgtcatcttcactacctatgccatgttgccc ttgggcatgcgggacgccacagctgcgggcctcacctcctccctctcacacctgctggtc ctcgggctgtatcttgggcctcaacgagactcaagacctgcgctgctgccgcagttggca gcaaacgcggtgttgttcctgtgcgggaatgtggcgggagcgtaccacaaggcgctgatg gagcgcgcgctgcgcgccaccttccgagaggcgctcagttccttgcactcgcgccggcgg ctggacacggagaagaagcaccaggaacaccttctcttgtccatccttcctgcctacttg gcccgagagatgaaggcagagatcatggcccggctgcaggctggacaggggtcaaggccg gagagcaccaacaacttccacagcctctatgtcaagaggcaccagggagtcagcgtgctg tatgctgacatcgtgggcttcacacggctggccagtgagtgctccccgaaggagttggtg ctcatgctcaatgagctctttggcaagtttgaccagatcgccaaggagcatgaatgcatg cggatcaagatcctgggagactgttactactgtgtctccgggctgcccctctccttacca gaccacgccatcaactgcgtgcgcatggggctggacatgtgccgggccatcaggaaacta cgagcagccaccggtgtggacatcaacatgcgcgtgggtgtgcactcaggcagcgtgctc tgtggagtcatcgggctgcagaagtggcagtatgatgtctggtcccatgacgtcacactg gccaaccacatggaggcaggtggcgtgccaggacgagtacatatcacaggggctaccctg gccctgctggcaggagcttacgctgtggaggatgcagccatagaacaccgggacccatac cttcgggagctaggggagcctacgtacctggtcatcgatccccgggctgaggaagaggat gagaagggcactgcaggagggttgctgtcctctcttgagggccccaagatgcgtccatca ctgctgatgacccgctacctggaatcctggggtgcagccaagccttttgcccacctgagc cacgtagagagccctgtgtccacctccactcctctcccggagaaggccctggcttccttc agcccccagtggagcctggaccggagccgtacaccccggggactagatgatgaaatggac actggggatgccaagttcttccaagtcatcgaacagctcaactctcagaaacagtggaag cagtcaaaggacttcaacccactgacactttacttccgagagaaggaaatggagaaagag tatcgactctctgcactccctgcctttaaatactatgcagcctgcacattcctggttttt ctctccaacttcatcatccagatgctggtgacaaacaggcccccagctctggccatcacc tatagcatcaccttcctcctcttcttcctcctcctcttcgtctgcttctcagagcacctg acgaggtgcgtcttgaaaggccccaagatgctgcactggctgccctcattgtctggcctg gtggccacacggcctggactgcgaatcgccctgggcagtgccaccatcctcctcatcttt gccatggccattaccagcctgttcttcttaccggcagcatcaaactgcccttttcgggct accaatgtgtcctccatggctttcaacctctcctgggagctccctgggtccctgcctctc atcagtattccatactccatgcactgctgcgtgctgggtttcctctcctgctccctcttt ctgcacatgagcttcgaactgaagctgctgctgctcctgctatggctggtggcctcctgc tgcctcttcctgcactcccatgcctggctgtccgactgcctcgtcgcccgcctctatctg ggctccttggactctaggccaggggtgctgaaggagcccaaactgatgggagctatctct ttcttcatcttcttcttcacactccttgtcttggctcggcagaatgaatattattgccgc ctggatttcctgtggaagaagaagctgaggcaggagcgggaggaaacagagacaatggag aatctgactcggctgctcttggagaacgtgctgcctgcacacgtggccccccagtttatt ggccagaaccggcgcaatgaggacctctaccaccagtcctatgagtgtgtctgtgtcctc ttcgcctcagtcccagacttcaaggagttttactctgaatccaacatcaaccacgagggg ctagagtgtctgcggctgctcaatgagatcattgctgattttgatgagctgctctctaag cccaagttcagtggggtggagaaaatcaaaaccatcggcagcacctacatggcagctaca ggcttaaatgccacctctggacaggatgcacagcaggatgctgagcgaagctgcagccac ctcggcaccatggtggaatttgcagtggcccttgggtctaagctggacgttatcaacaag cactcattcaacaacttccgcttgcgtgtggggctaaaccatggacctgtagtggccgga gtgataggagcccagaaaccacaatatgacatctggggcaacacggtgaatgtggccagt cgcatggagagtacaggagtcctgggcaagatacaagtgactgaggagacagcccgggcc ctgcagtccttaggctacacctgctacagcaggggtgttatcaaggtcaaaggcaaaggg cagctgtgtacctacttcctcaacacagatttgataagagttggacctccctcagctgcc ctaggctga

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