Myotis brandtii (Brandt's bat): 102260801 Help Entry 102260801         CDS       T02920                                  Symbol JAK1 Name (RefSeq) Janus kinase 1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism myb  Myotis brandtii (Brandt's bat) Pathway myb01521   EGFR tyrosine kinase inhibitor resistance myb04151   PI3K-Akt signaling pathway myb04217   Necroptosis myb04380   Osteoclast differentiation myb04550   Signaling pathways regulating pluripotency of stem cells myb04620   Toll-like receptor signaling pathway myb04621   NOD-like receptor signaling pathway myb04630   JAK-STAT signaling pathway myb04658   Th1 and Th2 cell differentiation myb04659   Th17 cell differentiation myb05140   Leishmaniasis myb05145   Toxoplasmosis myb05152   Tuberculosis myb05160   Hepatitis C myb05161   Hepatitis B myb05162   Measles myb05163   Human cytomegalovirus infection myb05164   Influenza A myb05165   Human papillomavirus infection myb05166   Human T-cell leukemia virus 1 infection myb05167   Kaposi sarcoma-associated herpesvirus infection myb05168   Herpes simplex virus 1 infection myb05169   Epstein-Barr virus infection myb05171   Coronavirus disease - COVID-19 myb05200   Pathways in cancer myb05203   Viral carcinogenesis myb05212   Pancreatic cancer myb05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:myb00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     102260801 (JAK1)    04151 PI3K-Akt signaling pathway     102260801 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     102260801 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     102260801 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     102260801 (JAK1)    04621 NOD-like receptor signaling pathway     102260801 (JAK1)    04658 Th1 and Th2 cell differentiation     102260801 (JAK1)    04659 Th17 cell differentiation     102260801 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     102260801 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102260801 (JAK1)    05203 Viral carcinogenesis     102260801 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102260801 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     102260801 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102260801 (JAK1)    05161 Hepatitis B     102260801 (JAK1)    05160 Hepatitis C     102260801 (JAK1)    05171 Coronavirus disease - COVID-19     102260801 (JAK1)    05164 Influenza A     102260801 (JAK1)    05162 Measles     102260801 (JAK1)    05168 Herpes simplex virus 1 infection     102260801 (JAK1)    05163 Human cytomegalovirus infection     102260801 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     102260801 (JAK1)    05169 Epstein-Barr virus infection     102260801 (JAK1)    05165 Human papillomavirus infection     102260801 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     102260801 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     102260801 (JAK1)    05140 Leishmaniasis     102260801 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102260801 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:myb01001]     102260801 (JAK1) Enzymes [BR:myb01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102260801 (JAK1) Protein kinases [BR:myb01001]  Non-receptor tyrosine kinases   JAK family [OT]    102260801 (JAK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 SH2_1 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  102260801 NCBI-ProteinID:  XP_005868086 LinkDB All DBs Position Un AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLSDREPLRLGSGEYTAEEL CIRAAQECCISPLCHNLFALYDEITKLWYAPNRSITVDDKTSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMIKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN WLNPNDNGNVLYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKPEMLGGQKQFKNFQIEVQKGRYSLHGSDRGFPSLGELMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIYSGT LVDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPNNRTT FQNLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaggaggactgcaatgccatggctttctgtgctaaaatgcgg agctccaagaagaccgaggtgaacctggaggcccctgagccaggggtagaagtgctcttc tatctgtcggacagggagcccctccggctgggtagcggggagtacacggcggaggagctg tgcatcagggcggcgcaggagtgctgtatctctcccctgtgccacaacctctttgccctg tatgatgagatcaccaagctctggtatgctccaaatcgcagcattactgtcgacgacaag acatcactccggctccactaccggatgaggttctattttaccaactggcacgggactaat gataatgagcagtcggtatggcgacattctccaaagaagcagaaaaatggctacgagaaa aaaaaagttccagatgcaacccctctccttgacgccagctctctggagtatctgtttgcc cagggacagtatgatttggtcaaatgcctggctcccatccgagaccccaagactgagcag gatgggcacgacattgagaacgagtgcctgggcatggccgtactggccatctcacactac gccatgatcaagaagatgcagttgccagaactccccaaggacatcagctacaagcggtat attccagaaacattgaataagtccatcagacagaggaaccttcttaccaggatgcggata aataatgtcttcaaggatttcctaaaggaatttaacaacaagaccatttgtgacagcagc gtgtccacgcatgacctgaaggtgaaatacctggcgaccttggaaactttgacaaaacat tacggtgctgaaatatttgagacttccatgttactgatttcatcggaaaatgagatgaat tggcttaatccgaatgacaatggaaatgttctctactatgaagtgatggtgactggaaat cttggaatccaatggaggcagaaaccaaatgtggttcctgttgaaaaggaaaaaaataaa ttgaaacggaaaaaactggaaaataaacacaagaaggacgaggagaaaaacaaaatccga gaagagtggaacaatttttcgtacttccctgaaatcactcacattgtaataaaggagtct gtggtcagcattaacaagcaggacaacaaaaagatggaactgaagctctcttcccacgag gaggccttgtcctttgtgtccctggtagacggctactttcggctcacagcagacgcccat cattacctctgcaccgatgtggctcctccattgattgtccacaacatacagaatggctgt cacggcccaatctgcacagagtatgccatcaataaactgcggcaagaaggaagcgaggag ggcatgtatgtgctgcgatggagctgcacggactttgacaacatcctcatgaccgtcacc tgctttgaaaagcctgagatgctgggtggccagaaacagttcaagaactttcagatcgag gtgcagaagggtcgctacagtctgcacggctcggaccgcggcttccccagcctgggggag ctcatgagccacctcaagaagcagatcctgcgcacggacaacatcagcttcgtgttgaag cgctgctgccagcccaagccccgagaaatctccaatctgctggtggctacgaagaaagcc caggagtggcagccggtctaccccatgagtcagctgagtttcgatcggatcctcaagaaa gacatcatgcaaggagagcaccttgggagaggcacgcggacacacatctactctgggacc ctggtggattacaaggatgacgaaggaacttctgaagagaagaaaataaaagtgatcctc aaagtcttggaccccagccacagggacatttctctggccttcttcgaggcagccagcatg atgagacaggtctcccacaaacacattgtgtacctctacggtgtctgtgtgcgagacgtg gagaatatcatggtggaagagtttgtggagggcgggcctctggatctcttcatgcacagg aaaagcgacgtcctcaccactccgtggaaattcaaagttgctaaacagctggccagtgcc ctgagttacttggaggataaagacctggtccacggaaacgtgtgcactaaaaacctcctc ctggcccgtgaaggcatcgacagcgagtgtggcccgttcatcaagctcagtgaccctggc atccccatcactgtgctgtccaggcaagaatgcatagaacgaatcccatggattgctccc gagtgtgtagaagattccaagaacctgagcgtggccgctgacaaatggagctttggaacc acactctgggaaatctgctataatggcgagatccccctgaaagataagacactgattgag aaagagagattctacgaaagccggtgcagaccagtgacaccgtcttgtaaggagctggct gaccttatgactcgctgcatgaactacgaccccaaccagagaccctttttccgagccatc atgagagacatcaataagctggaagagcaaaatccagacatcgtttcagagaaaaagcca gcaaccgaagtggatcccacacattttgaaaagcgcttcttaaagagaatccgtgacttg ggagagggccactttgggaaggttgagctctgcaggtatgaccctgaaggggacaataca ggagagcaggtggctgtcaaatccctgaagcctgagagtggagggaaccacatagctgat ctgaagaaggaaattgaaatcttaaggaacctctatcacgagaacattgtcaagtacaaa ggcatctgcacagaggatggaggaaatggtattaagctcatcatggaatttctgccttct ggaagccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcagtta aaatatgctgttcagatttgtaaggggatggactatttggggtcacgacagtatgttcac cgggacttagcagcaaggaatgtccttgttgaaagtgagcaccaagtgaaaattggagac tttggtttaactaaagcaattgaaaccgataaggagtactacacagtcaaggatgaccgg gacagccctgtgttctggtacgccccagaatgtctaattcagtgtaaattttatattgcc tctgacgtctggtccttcggagtgactctgcacgagctgcttacttactgtgattcagat tccagtcccatggctttgttcctgaaaatgataggccccactcacggccagatgacagta acgagacttgtgaacacattgaaagaaggaaaacgtttgccttgtcctcccaactgtcca gatgaggtttatcaacttatgagaaaatgctgggaattccaaccaaataatcggacaacc ttccagaaccttattgaaggatttgaggcacttttaaaataa

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