Myotis brandtii (Brandt's bat): 102261553 Help Entry 102261553         CDS       T02920                                  Symbol PLCG2 Name (RefSeq) phospholipase C gamma 2   KO K05859   phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11] Organism myb  Myotis brandtii (Brandt's bat) Pathway myb00562   Inositol phosphate metabolism myb01100   Metabolic pathways myb01521   EGFR tyrosine kinase inhibitor resistance myb04012   ErbB signaling pathway myb04014   Ras signaling pathway myb04020   Calcium signaling pathway myb04062   Chemokine signaling pathway myb04064   NF-kappa B signaling pathway myb04066   HIF-1 signaling pathway myb04070   Phosphatidylinositol signaling system myb04072   Phospholipase D signaling pathway myb04360   Axon guidance myb04370   VEGF signaling pathway myb04380   Osteoclast differentiation myb04611   Platelet activation myb04613   Neutrophil extracellular trap formation myb04625   C-type lectin receptor signaling pathway myb04650   Natural killer cell mediated cytotoxicity myb04662   B cell receptor signaling pathway myb04664   Fc epsilon RI signaling pathway myb04666   Fc gamma R-mediated phagocytosis myb04670   Leukocyte transendothelial migration myb04722   Neurotrophin signaling pathway myb04750   Inflammatory mediator regulation of TRP channels myb04919   Thyroid hormone signaling pathway myb04933   AGE-RAGE signaling pathway in diabetic complications myb04935   Growth hormone synthesis, secretion and action myb05167   Kaposi sarcoma-associated herpesvirus infection myb05169   Epstein-Barr virus infection myb05170   Human immunodeficiency virus 1 infection myb05171   Coronavirus disease - COVID-19 myb05200   Pathways in cancer myb05205   Proteoglycans in cancer myb05206   MicroRNAs in cancer myb05214   Glioma myb05223   Non-small cell lung cancer myb05225   Hepatocellular carcinoma Module myb_M00130   Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Brite KEGG Orthology (KO) [BR:myb00001]  09100 Metabolism   09101 Carbohydrate metabolism    00562 Inositol phosphate metabolism     102261553 (PLCG2)  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     102261553 (PLCG2)    04014 Ras signaling pathway     102261553 (PLCG2)    04370 VEGF signaling pathway     102261553 (PLCG2)    04064 NF-kappa B signaling pathway     102261553 (PLCG2)    04066 HIF-1 signaling pathway     102261553 (PLCG2)    04020 Calcium signaling pathway     102261553 (PLCG2)    04070 Phosphatidylinositol signaling system     102261553 (PLCG2)    04072 Phospholipase D signaling pathway     102261553 (PLCG2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102261553 (PLCG2)    04613 Neutrophil extracellular trap formation     102261553 (PLCG2)    04625 C-type lectin receptor signaling pathway     102261553 (PLCG2)    04650 Natural killer cell mediated cytotoxicity     102261553 (PLCG2)    04662 B cell receptor signaling pathway     102261553 (PLCG2)    04664 Fc epsilon RI signaling pathway     102261553 (PLCG2)    04666 Fc gamma R-mediated phagocytosis     102261553 (PLCG2)    04670 Leukocyte transendothelial migration     102261553 (PLCG2)    04062 Chemokine signaling pathway     102261553 (PLCG2)   09152 Endocrine system    04935 Growth hormone synthesis, secretion and action     102261553 (PLCG2)    04919 Thyroid hormone signaling pathway     102261553 (PLCG2)   09156 Nervous system    04722 Neurotrophin signaling pathway     102261553 (PLCG2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102261553 (PLCG2)   09158 Development and regeneration    04360 Axon guidance     102261553 (PLCG2)    04380 Osteoclast differentiation     102261553 (PLCG2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102261553 (PLCG2)    05206 MicroRNAs in cancer     102261553 (PLCG2)    05205 Proteoglycans in cancer     102261553 (PLCG2)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     102261553 (PLCG2)    05214 Glioma     102261553 (PLCG2)    05223 Non-small cell lung cancer     102261553 (PLCG2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102261553 (PLCG2)    05171 Coronavirus disease - COVID-19     102261553 (PLCG2)    05167 Kaposi sarcoma-associated herpesvirus infection     102261553 (PLCG2)    05169 Epstein-Barr virus infection     102261553 (PLCG2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     102261553 (PLCG2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102261553 (PLCG2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:myb04131]     102261553 (PLCG2) Enzymes [BR:myb01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.11  phosphoinositide phospholipase C      102261553 (PLCG2) Membrane trafficking [BR:myb04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     102261553 (PLCG2)  Endocytosis   Macropinocytosis    Phospholipase C     102261553 (PLCG2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PI-PLC-X SH2 PI-PLC-Y EF-hand_PLCG2 C2 SH3_1 SH3_9 PH EF-hand_PLCG1 PH_12 SH2_1 SH3_2 PH_14 Adhesin_E EF-hand_like Motif Other DBs NCBI-GeneID:  102261553 NCBI-ProteinID:  XP_005862641 UniProt:  S7PCD7 LinkDB All DBs Position Un AA seq 1265 aa AA seqDB search MTTMVNVDALPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK IEGFLDIMEIKEIRPGKSSKDFERAKAVRQKEDCCFTILYGTQFVLSTLSLATDSKEDAT KWLSGLKILHQEAMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKAILPLVNFKVSSA KFLKDKFAEIGANKDEFSFEQFHLLYKKLMFEQQKSILDEFKKDSSVFILGSTDRPDASA VHLHDFQRFLLHEQQELWAQDVNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS IWDEKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDC WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCCVEQQRYMARV FKEVFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGE LYMWDPIDLKWTRHYCAIADAKLSFSDDIEQTVEEEVPQDTPPTELHFGEKWFHKKVEKR TSAEKLLQEYCSETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGTMKYY LTDNLMFTSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDML MRVPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY EKHALYRKMKLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY KAKQSDELSFCRGALIHNVSKEPGGWWKGDYGTKIQHYFPSNYVEDISTVDVEELEKQII EDNPLGSLCKGILDLNTYNVVKAPHGKNQKPFVFILEPKKQGDPPVEFATDRVEELFEWF QSIRQITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE TKADSVIRQKPIELLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTGDKY MQMNQALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSI ACPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWASTQEKVTFEIYDPNLAFLRFVVYEED MFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC RQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLHLYQEKCNRRLREKRVSN SKFYS NT seq 3798 nt NT seq  +upstreamnt  +downstreamnt atgaccaccatggtcaacgtggacgccctcccggaatatgagaagagtcagatcaagaga gccctggagctgggcaccgtgatgaccgtgttcagcttccgcaagtccaccccggagcgc aggaccgtccaggtgatcatggagacgcggcaggtggcctggagtaagacggccgacaag atcgagggcttcttggatatcatggaaatcaaggaaatccgcccagggaagagctccaag gattttgagcgtgcaaaggcagtccgccagaaggaagactgctgcttcaccatcttgtat ggcacccagttcgtcctcagcacactcagcttagcaactgactcgaaggaagatgcaacc aagtggctctctggcttgaaaatcttacaccaagaagcgatgagcgcgtccacacccacc atcattgagagttggctgaggaagcagatttattcggtggatcaaaccagaagaaacagc atcagcctccgagagttgaaggccatcttgcccctggtcaacttcaaagtgagcagtgcc aagttcctcaaggataagtttgcggaaataggcgcaaacaaagatgaattcagctttgaa cagttccatctcctctataaaaaacttatgtttgaacagcaaaaatcgattcttgacgaa ttcaaaaaagattcctccgtgttcatcctgggcagtactgaccggccggatgcctccgcg gttcacctgcatgacttccagcggtttctcttacatgaacagcaggaactttgggctcag gatgtgaacaaagtccgtgagaggatgacaaagtttatcgacgacacgatgagggaaact gcggagcccttcttgtttgttgatgagttcctcacgtacctgttttcacgggagaacagc atttgggatgagaagtacgacgtggtggacatgcaggacatgaacaaccccttgtctcat tactggatctcctcgtcacataacacgtacctcacaggtgaccagctgcggagtgagtcg tccccggaggcgtatatccgctgtctgcgcatgggctgtcgctgcattgagttggactgc tgggacgggcccgacgggaagcccatcatctaccacggctggacccggaccaccaagatc aagtttgatgacgttgtgcaggccatcaaagaccacgcctttgtcacctcaagcttcccc gtgatcctgtccatcgaggagcactgttgtgtggagcagcagcgctacatggccagagtg ttcaaggaggtatttggcgacctgctgctgacaaagcccacggaggccagtgctgaccag ctgccctcgcccagccagctgcgggagaagatcatcatcaagcacaagaagctgggcccc cgaggcgacgtggatgtcaacatggaggacaagaaagatgagcacaagcagcagggggag ctgtacatgtgggaccccatcgacctgaaatggactcggcactactgcgccattgctgat gccaagctgtccttcagcgacgacattgagcagactgtggaagaggaagtgccccaggac acgccccccacagagctgcattttggagagaagtggttccacaagaaggtggagaagagg acaagtgctgagaagctgttgcaggaatactgctcagagaccgggggcaaggacgggacc ttcctggtgcgggagagcgagacattccccaacgactacaccctgtccttctggcggtcc ggccgggtccagcactgccggatccgctccaccatggagggcgggaccatgaagtactac ctgactgacaacctcatgttcaccagcatctacgccctcatccagcactaccgcgagacg cacctgcgctgcgccgagttcgagctccgactcaccgaccccgtgcccaaccccaacccc catgaatcaaagccgtggtactacgacgggctgagccgtggagaagcggaggacatgctg atgagggttccccgggacggcgccttcctcatccggaagcgggaaggtagcgactcctac gccatcaccttcagggcccggggcaaggtgaagcactgccgcatcaaccgggacggccgg cacttcgtgctggggacctccgcctacttcgagagcctggtggagctcgtcagctactac gagaagcacgcgctctaccggaagatgaagctgcgctaccccgtgacgcccgagctcctg gagcgctacaacatggaaagagatataaactccctgtatgacgtcagcagaatgtatgtg gatcccagtgaaatcaatccttctatgcctcagagaaccgtgaaagctctgtatgactac aaagccaagcagagtgatgagctgagcttctgccgcggcgccctcatccacaacgtctcc aaggagcccgggggctggtggaaaggagactacggaaccaaaatccagcactacttcccg tccaattacgtcgaggacatttcaacggttgatgtggaggagctcgagaagcagattatt gaagacaatcccttagggtctctttgcaaaggaatattggatctcaacacctataacgtt gtgaaagccccgcacgggaaaaaccagaagcccttcgtcttcatcctggagcccaagaag cagggtgacccgccggtggagttcgccacggaccgggtggaggagctcttcgagtggttc cagagcatccggcagatcacctggaagatcgacaccaaggagaacaacatgaaatactgg gagaagaaccagtcgatcgccatcgagctctcggacctggtcgtctactgcaaaccaacc agcaagaccaaagataatttagagaatcccgacttccgagagatccgttcctttgtggag acgaaggccgacagcgtcatcagacagaaacccattgagctcctgaagtacaatcagaag ggcctgacccgtgtttacccgaagggacagagggtggactcctccaactacgaccccttc cgcctctggctgtgcggctcccaaatggtggcactcaatttccagactggagacaaatac atgcagatgaatcaggccttgttttcactcaatgggaggaccggctacgtcctgcaaccc gagagcatgaggacggagaagtacgaccccatgccgcccgagtcccagaggaagattctg atgaccttgacggtcaaggttctcggggctcgccatctccccaagctcggacgaagtatt gcatgtccctttgtggaggtggaaatatgtggagccgaatatgacaacaacaagtttaag acgacggttgtgaatgacaatggcctaagccctgtttgggcttcaacgcaggagaaggtg acatttgaaatctatgacccaaacctggcatttctgcgctttgtggtgtacgaggaagat atgttcagcgaccccaactttctcgcgcatgctacttaccccattaaaggaatcaagtca ggatttagatctgttcctctgaagaacgggtacagtgaagacattgagctggcttccctc ctggttttttgtgagatgcggccagtgctggagagtgaagaggaactgtactcttcctgt cgccagctgcggaggcggcaagaagagctgaacaaccagctcttcctatatgacacacac cagaacttgcgcaatgccaaccgggatgccctcgttaaagagttcaatgtcaacgagaac cagctccatctgtaccaggagaagtgcaaccggaggttaagagagaagagagtcagcaac agcaagttttactcatag

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