Myotis davidii (David's myotis): 102755123 Help Entry 102755123         CDS       T02992                                  Symbol PLCB3 Name (RefSeq) phospholipase C beta 3   KO K05858   phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] Organism myd  Myotis davidii (David's myotis) Pathway myd00562   Inositol phosphate metabolism myd01100   Metabolic pathways myd04015   Rap1 signaling pathway myd04020   Calcium signaling pathway myd04022   cGMP-PKG signaling pathway myd04062   Chemokine signaling pathway myd04070   Phosphatidylinositol signaling system myd04071   Sphingolipid signaling pathway myd04072   Phospholipase D signaling pathway myd04081   Hormone signaling myd04082   Neuroactive ligand signaling myd04261   Adrenergic signaling in cardiomyocytes myd04270   Vascular smooth muscle contraction myd04310   Wnt signaling pathway myd04371   Apelin signaling pathway myd04540   Gap junction myd04611   Platelet activation myd04613   Neutrophil extracellular trap formation myd04621   NOD-like receptor signaling pathway myd04713   Circadian entrainment myd04720   Long-term potentiation myd04723   Retrograde endocannabinoid signaling myd04724   Glutamatergic synapse myd04725   Cholinergic synapse myd04726   Serotonergic synapse myd04728   Dopaminergic synapse myd04730   Long-term depression myd04742   Taste transduction myd04750   Inflammatory mediator regulation of TRP channels myd04911   Insulin secretion myd04912   GnRH signaling pathway myd04915   Estrogen signaling pathway myd04916   Melanogenesis myd04918   Thyroid hormone synthesis myd04919   Thyroid hormone signaling pathway myd04921   Oxytocin signaling pathway myd04922   Glucagon signaling pathway myd04924   Renin secretion myd04925   Aldosterone synthesis and secretion myd04926   Relaxin signaling pathway myd04927   Cortisol synthesis and secretion myd04928   Parathyroid hormone synthesis, secretion and action myd04929   GnRH secretion myd04933   AGE-RAGE signaling pathway in diabetic complications myd04934   Cushing syndrome myd04935   Growth hormone synthesis, secretion and action myd04961   Endocrine and other factor-regulated calcium reabsorption myd04970   Salivary secretion myd04971   Gastric acid secretion myd04972   Pancreatic secretion myd04973   Carbohydrate digestion and absorption myd05010   Alzheimer disease myd05016   Huntington disease myd05017   Spinocerebellar ataxia myd05022   Pathways of neurodegeneration - multiple diseases myd05142   Chagas disease myd05143   African trypanosomiasis myd05146   Amoebiasis myd05163   Human cytomegalovirus infection myd05200   Pathways in cancer myd05415   Diabetic cardiomyopathy myd05417   Lipid and atherosclerosis Module myd_M00130   Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Brite KEGG Orthology (KO) [BR:myd00001]  09100 Metabolism   09101 Carbohydrate metabolism    00562 Inositol phosphate metabolism     102755123 (PLCB3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102755123 (PLCB3)    04310 Wnt signaling pathway     102755123 (PLCB3)    04371 Apelin signaling pathway     102755123 (PLCB3)    04020 Calcium signaling pathway     102755123 (PLCB3)    04070 Phosphatidylinositol signaling system     102755123 (PLCB3)    04072 Phospholipase D signaling pathway     102755123 (PLCB3)    04071 Sphingolipid signaling pathway     102755123 (PLCB3)    04022 cGMP-PKG signaling pathway     102755123 (PLCB3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102755123 (PLCB3)    04081 Hormone signaling     102755123 (PLCB3)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04540 Gap junction     102755123 (PLCB3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102755123 (PLCB3)    04613 Neutrophil extracellular trap formation     102755123 (PLCB3)    04621 NOD-like receptor signaling pathway     102755123 (PLCB3)    04062 Chemokine signaling pathway     102755123 (PLCB3)   09152 Endocrine system    04911 Insulin secretion     102755123 (PLCB3)    04922 Glucagon signaling pathway     102755123 (PLCB3)    04929 GnRH secretion     102755123 (PLCB3)    04912 GnRH signaling pathway     102755123 (PLCB3)    04915 Estrogen signaling pathway     102755123 (PLCB3)    04921 Oxytocin signaling pathway     102755123 (PLCB3)    04926 Relaxin signaling pathway     102755123 (PLCB3)    04935 Growth hormone synthesis, secretion and action     102755123 (PLCB3)    04918 Thyroid hormone synthesis     102755123 (PLCB3)    04919 Thyroid hormone signaling pathway     102755123 (PLCB3)    04928 Parathyroid hormone synthesis, secretion and action     102755123 (PLCB3)    04916 Melanogenesis     102755123 (PLCB3)    04924 Renin secretion     102755123 (PLCB3)    04925 Aldosterone synthesis and secretion     102755123 (PLCB3)    04927 Cortisol synthesis and secretion     102755123 (PLCB3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102755123 (PLCB3)    04270 Vascular smooth muscle contraction     102755123 (PLCB3)   09154 Digestive system    04970 Salivary secretion     102755123 (PLCB3)    04971 Gastric acid secretion     102755123 (PLCB3)    04972 Pancreatic secretion     102755123 (PLCB3)    04973 Carbohydrate digestion and absorption     102755123 (PLCB3)   09155 Excretory system    04961 Endocrine and other factor-regulated calcium reabsorption     102755123 (PLCB3)   09156 Nervous system    04724 Glutamatergic synapse     102755123 (PLCB3)    04725 Cholinergic synapse     102755123 (PLCB3)    04728 Dopaminergic synapse     102755123 (PLCB3)    04726 Serotonergic synapse     102755123 (PLCB3)    04720 Long-term potentiation     102755123 (PLCB3)    04730 Long-term depression     102755123 (PLCB3)    04723 Retrograde endocannabinoid signaling     102755123 (PLCB3)   09157 Sensory system    04742 Taste transduction     102755123 (PLCB3)    04750 Inflammatory mediator regulation of TRP channels     102755123 (PLCB3)   09159 Environmental adaptation    04713 Circadian entrainment     102755123 (PLCB3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102755123 (PLCB3)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     102755123 (PLCB3)   09174 Infectious disease: parasitic    05146 Amoebiasis     102755123 (PLCB3)    05142 Chagas disease     102755123 (PLCB3)    05143 African trypanosomiasis     102755123 (PLCB3)   09164 Neurodegenerative disease    05010 Alzheimer disease     102755123 (PLCB3)    05016 Huntington disease     102755123 (PLCB3)    05017 Spinocerebellar ataxia     102755123 (PLCB3)    05022 Pathways of neurodegeneration - multiple diseases     102755123 (PLCB3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102755123 (PLCB3)    05415 Diabetic cardiomyopathy     102755123 (PLCB3)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     102755123 (PLCB3)    04934 Cushing syndrome     102755123 (PLCB3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:myd04131]     102755123 (PLCB3) Enzymes [BR:myd01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.11  phosphoinositide phospholipase C      102755123 (PLCB3) Membrane trafficking [BR:myd04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     102755123 (PLCB3)  Endocytosis   Macropinocytosis    Phospholipase C     102755123 (PLCB3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PLC-beta_C PI-PLC-X PI-PLC-Y PH_14 PLCB1-4-like_EFh EF-hand_like C2 Motif Other DBs NCBI-GeneID:  102755123 NCBI-ProteinID:  XP_015424468 LinkDB All DBs Position Un AA seq 1213 aa AA seqDB search PSLGCSPHPLTPIVSSLPQEASSRNLVTLRVDSNGFFLYWTGPNMEVDTLDISSIRDTRT GRYARLPKDPKIREVLGFGGPDARLEEKLMTVVAGPDPVNTTFLNFMAVQDDTAKVWAEE LFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFSADKKRVETALESCG LNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPYLTLEQLMDFINQKQ RDPRLNEVLYPPLGPSQTRLLIEKYEPNKQFLERDQMSMEGFSRYLGGEENGILPLEALD LSADMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRCVELDVWKGRPPEEE PFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAKQQAKMAEYCRSIFG DALLIDPLDKYPVSAGPDLSVPTAVGRILVKNKKRHRPSTGVPSSSVRKRPLEQSNSALS ESSAATEPSSPQLGSPSSDSCPGLSNGEEAGLEKLSLEPRKSLSEEGPQRGPDLGPADRE EEEEDEEEEEQPDPKKPTTDEGTASSEVNATEEMSTLVNYIEPVKFKSFEAARKRNKCFE MSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYMPQLFWNVGCQLVALNF QTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEGIVDGIVANALRVKVISGQ FLSDRKVSIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEPFDFPKVVLPTLASLRI AAFEEGGKFVGHRILPVSAIRSGYHYICLRNEANQPLCLPALLIYTEASDYIPDDHQNYA EALINPIKHVSLMDQRAKQLAALIGEREAQAGPETSQETQSPQQGSQLTPNPTPSPLDTS PRRPPGPTTSPTSPSLSSPGQRDDLIASILSEVAVAPLEELRGHKALVKLRSRQERDLRE LHKKHQRKAFALTRRLLDSLAQARAESRCQPRAGVLVGEDRKEEEAARRYQEFQRRQVQS LLELREAQADAEAERKLEHLRQALQRLREIVLEAHTTQVKRLKEMNDREKKELQKILDRK RHNSISEAKTREKHKKEAELTEINRRHITESVNSIRRLEEAQKQRHERLVAGQQQVLQQL LEEEPKLLAQLAQECQEHRARLPQEIRRCLLGETSEGLGDGHLVACASNGHVPGSSGHLS GADSESQEENTKL NT seq 3642 nt NT seq  +upstreamnt  +downstreamnt ccaagcctgggctgcagccctcaccccttgacccctattgtgtcatcccttccccaggag gcctccagtcggaacctggtgaccctgcgcgtggactccaatggcttcttcctgtactgg acaggacccaacatggaggtggacacactggacatcagttccatcagggacacacggaca ggccgttacgcccgcctgcccaaggaccccaagattcgcgaggtgctgggttttgggggc cctgatgcccggctagaagagaagctgatgacggtggtggccgggccagaccccgtgaac acaaccttcttgaacttcatggccgtgcaggacgacacagccaaggtctgggctgaggag ctgttcaagctggccatgaacatcttggctcagaacgcctccaggaacaccttcctgcgc aaagcgtacacaaagctgaagctgcaggtgaaccaggatggacggatcccggtcaagaac atcctgaagatgttctcagcagacaagaagcgggtggagactgcactggagtcctgtggc ctcaattttaaccggagcgagtccatccggcctgatgagttttccttggaaatctttgag cggttcctgaacaagttgtgtcttcgaccggacatcgacaagatcctgctggagataggt gccaagggcaagccgtacctgacactggagcagctcatggacttcatcaaccagaagcaa cgggacccaaggctcaatgaagtgctgtacccgcccctggggccctcccagacccggctg ctcattgagaagtatgagcccaacaagcagttcctggagcgagaccagatgtccatggag ggcttcagccgctacctgggaggggaggagaatggcattctgcccctggaggccctggat ctgagcgcagacatgacccagccactgagcgcctacttcatcaactcctcacacaacacc tatctcacagcggggcagctggccgggacctcctcggtggagatgtaccgccaggcgctg ctgtggggctgccgctgcgtggagctggacgtgtggaaagggcggccgccggaggaggag cccttcatcacccacggcttcaccatgaccacggaggtgccgctgcgggacgtgctggag gccatcgctgagaccgcgttcaagacctcgccctacccggtcatcctctccttcgagaac cacgtggactcggcaaagcagcaggccaagatggccgagtactgccgctccatctttggg gatgcgctgctcatcgacccgctggacaagtacccggtatcggctggccctgacctgtct gtgcccacagctgtggggcgcatcctggtgaagaacaagaagcggcaccggcccagcacg ggcgtccccagcagctccgtgcgcaagcggccgctggagcagagcaactcggccctgagc gagagctccgccgccaccgagccctcctccccgcagctcgggtcccccagctccgacagc tgcccaggcctgagcaatggggaggaggcaggtctggagaagctgagcctggagcctcgg aagtctctgagcgaggaggggccacagcggggccccgatcttggacctgccgaccgtgag gaggaggaggaggatgaggaagaggaggagcagccagaccccaaaaagccgaccacggat gagggcactgctagcagtgaggtcaacgctactgaggagatgtcgacactcgtcaactac atcgagcccgtcaagttcaagtccttcgaggctgctcgaaagaggaacaagtgcttcgag atgtcatcctttgtggagacaaaggccatggaacagctgaccaagagccccatggagttt gtggaatacaacaagcagcagctcagccgcatctaccccaagggtacccgcgtggactcg tccaactacatgccccagctcttctggaacgtgggctgccagctcgtggctctcaacttc cagaccctggacgtggcgatgcagctcaacgcaggcgtgttcgagtacaacgggcgcagc ggctacctgctcaagcctgagttcatgaggcggccagacaagtcctttgaccccttcacc gagggcatcgtggatggcattgtggccaatgccttgcgggtcaaggtgatctcggggcag ttcctgtcggacaggaaggtgagcatctacgtggaggtggacatgttcggcctccccgtg gacacgcggcgcaagtaccgcactcggacctctcaggggaactcgttcaaccccgtgtgg gatgaggagccctttgacttccccaaggtggtgctgcccacgctggcttcgctgcgcatc gcggccttcgaggagggcggcaagtttgtggggcaccggatcctgcccgtctctgccatc cgctcagggtaccactacatctgcctaagaaacgaggccaaccagcctctgtgcctgcca gccctgctcatctacacggaggcctctgactacatccccgacgaccaccagaattatgca gaggccctgatcaaccccatcaagcatgtcagcctcatggaccagagggccaagcagctg gccgccctcatcggagagagggaggctcaggctggcccggagacaagccaggagacccag tctccgcagcaggggtcccagctgaccccaaaccccacacccagcccactggacacctct ccccggcggccccccggtcccaccacctcccccaccagcccttcccttagcagcccaggt cagcgggatgatctcattgccagtatcctgtcagaggtggctgtggccccgctggaggag ctccgaggccacaaggctctggtgaaactccggagtcggcaagagcgcgacctgcgggag ctgcacaagaagcaccagcggaaggcattcgctctcacccgccgactgctggacagcctg gcccaggcccgggccgagagcaggtgccagccccgggccggggtcctagtcggggaggac aggaaggaggaggaggcggcgaggcggtaccaggagttccagaggagacaggtgcagagt ctgctggagctgcgggaggcccaggcggacgccgaggccgagcggaagctggagcacctg agacaggctctgcagcggctcagggagattgtcctggaggctcacaccactcaggtcaag aggctgaaggagatgaatgacagggagaagaaggaattgcagaagatcctggacaggaag cgccacaacagtatctcggaggccaagacaagggagaagcataagaaggaggcggaactg acagagatcaaccgccgccacatcacggagtccgtcaactccatccgccggctggaggag gcccagaagcagcggcatgaacgcctggtggccgggcagcagcaggtcctacagcagctg ctggaagaggagcccaagctgctggcccagctggcccaggaatgtcaggagcaccgggcc aggctgccccaggagatccgccggtgtctgctgggcgagacgtcggaggggctgggggac ggacatctggtggcctgtgccagcaatggtcacgtgcctgggagcagtgggcacctgtcc ggtgctgactcggagagccaagaggagaatacgaagctctga

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