Myotis davidii (David's myotis): 102756517 Help Entry 102756517         CDS       T02992                                  Symbol JAK1 Name (RefSeq) Janus kinase 1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism myd  Myotis davidii (David's myotis) Pathway myd01521   EGFR tyrosine kinase inhibitor resistance myd04151   PI3K-Akt signaling pathway myd04217   Necroptosis myd04380   Osteoclast differentiation myd04550   Signaling pathways regulating pluripotency of stem cells myd04620   Toll-like receptor signaling pathway myd04621   NOD-like receptor signaling pathway myd04630   JAK-STAT signaling pathway myd04658   Th1 and Th2 cell differentiation myd04659   Th17 cell differentiation myd05140   Leishmaniasis myd05145   Toxoplasmosis myd05152   Tuberculosis myd05160   Hepatitis C myd05161   Hepatitis B myd05162   Measles myd05163   Human cytomegalovirus infection myd05164   Influenza A myd05165   Human papillomavirus infection myd05166   Human T-cell leukemia virus 1 infection myd05167   Kaposi sarcoma-associated herpesvirus infection myd05168   Herpes simplex virus 1 infection myd05169   Epstein-Barr virus infection myd05171   Coronavirus disease - COVID-19 myd05200   Pathways in cancer myd05203   Viral carcinogenesis myd05212   Pancreatic cancer myd05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:myd00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     102756517 (JAK1)    04151 PI3K-Akt signaling pathway     102756517 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     102756517 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     102756517 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     102756517 (JAK1)    04621 NOD-like receptor signaling pathway     102756517 (JAK1)    04658 Th1 and Th2 cell differentiation     102756517 (JAK1)    04659 Th17 cell differentiation     102756517 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     102756517 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102756517 (JAK1)    05203 Viral carcinogenesis     102756517 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102756517 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     102756517 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102756517 (JAK1)    05161 Hepatitis B     102756517 (JAK1)    05160 Hepatitis C     102756517 (JAK1)    05171 Coronavirus disease - COVID-19     102756517 (JAK1)    05164 Influenza A     102756517 (JAK1)    05162 Measles     102756517 (JAK1)    05168 Herpes simplex virus 1 infection     102756517 (JAK1)    05163 Human cytomegalovirus infection     102756517 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     102756517 (JAK1)    05169 Epstein-Barr virus infection     102756517 (JAK1)    05165 Human papillomavirus infection     102756517 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     102756517 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     102756517 (JAK1)    05140 Leishmaniasis     102756517 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102756517 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:myd01001]     102756517 (JAK1) Enzymes [BR:myd01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102756517 (JAK1) Protein kinases [BR:myd01001]  Non-receptor tyrosine kinases   JAK family [OT]    102756517 (JAK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 SH2_1 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  102756517 NCBI-ProteinID:  XP_006773301 LinkDB All DBs Position Un AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYPSDREPLRLGSGEYTAEEL CIRAAQECFISPLCHNLFALYDERTKLWYAPNRSITVDDKTSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMIKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN WFKPNDSGNVLYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKVR EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKPEVLGGQKQFKNFQIEVQKGRYSLHGSDRGFPSLGELMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIYSGT LVDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPNNRTT FQNLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaggaggactgcaatgccatggctttctgtgctaaaatgcgg agctccaagaagaccgaggtgaacctggaggcccctgagccaggggtggaagtgctcttc tatccgtcggacagggagcccctccgtctgggcagcggggagtacacggcggaggagctg tgcatcagggcggcgcaggagtgctttatctctcccctgtgccacaacctctttgccctg tatgatgagaggaccaagctctggtatgctccaaatcgcagcattactgtcgacgacaag acatcgctccggctccactaccggatgaggttctattttaccaactggcacgggactaat gataatgagcagtcggtatggcgacattctccaaagaagcagaaaaatggctacgagaaa aaaaaagttccagatgcaacccctctccttgacgccagctctctggagtatctgtttgcc cagggacagtatgatttggtcaaatgcctggctcccatccgagaccccaagactgagcag gatgggcacgacattgagaacgagtgcctgggcatggccgtgctggccatctcacactac gccatgatcaagaagatgcagttgccagaactccccaaggacatcagctacaagcgatat attccagaaacattgaataagtccatcagacagaggaaccttcttaccaggatgcggata aataatgtcttcaaggatttcctaaaggaatttaacaacaagaccatttgtgacagcagc gtgtccacgcatgacctgaaggtgaaatacctggcgaccttggaaacgttgacaaaacat tacggtgctgaaatatttgagacttccatgttactgatttcatcggaaaatgagatgaat tggtttaaaccgaatgacagtggaaatgttctctactatgaagtgatggtgactggaaat cttggaatccaatggaggcagaaaccaaatgtggttcctgttgaaaaggaaaaaaataaa ttgaaacggaaaaaactggaaaataaacacaagaaggacgaggagaaaaacaaagtccga gaagagtggaacaatttttcgtacttccctgaaatcactcacattgtaataaaggagtct gtggtcagcattaacaagcaggacaacaaaaagatggaactgaagctctcttcccatgag gaggccttgtcctttgtgtccctggtagatggctacttccggctcacagcagacgcccat cattacctctgcaccgatgtggctcctccattgattgtccacaacatacagaatggctgt cacggcccaatctgcacagagtatgccatcaataaactgcggcaagaaggaagcgaggag ggcatgtatgtgctgcgatggagctgcacagactttgacaacatcctcatgaccgtcacc tgctttgaaaagcctgaggtgctgggtggccagaaacagttcaagaactttcagatcgag gtgcagaagggtcgctacagtctgcacggctcggaccgtggcttccccagcctgggggag ctcatgagccacctcaagaagcagatcctgcgcacggacaacatcagcttcgtgttgaag cgctgctgccaacccaagccccgagaaatctccaatctgctggtggctacgaagaaagcc caggagtggcagcccgtctaccccatgagtcagctgagtttcgatcggatcctcaagaaa gacatcatgcaaggagagcaccttgggagaggcacgcggacacacatctactctgggacc ctggtggattacaaggatgacgaaggaacttctgaagagaagaaaataaaagtgatcctc aaagtcttggaccccagccacagggacatttctctggccttcttcgaggcagccagcatg atgagacaggtctcccacaaacacatcgtgtacctctacggtgtctgtgtccgagacgtg gagaatatcatggtggaagagtttgtggagggcgggcctctggacctcttcatgcaccgg aaaagcgacgtcctcaccactccgtggaaattcaaagttgctaaacagctggccagtgcc ctgagttacttggaggataaagacctggtccacggaaacgtgtgcactaaaaacctcctc ctggcccgtgaaggcatcgacagcgagtgtggcccgttcatcaagctcagtgaccctggc atccccatcactgtgctgtccaggcaagaatgcatagaacgaatcccatggattgctccc gagtgtgtagaagattccaagaacctgagcgtggccgctgacaaatggagctttggaacc acactctgggaaatctgctataatggcgagatccccctgaaagataagacactgattgag aaagagagattctacgaaagccggtgcagaccagtgacaccgtcttgtaaggagctggct gaccttatgactcgctgcatgaactacgaccccaaccagagaccctttttccgagctatc atgagagacatcaataagctggaagagcagaatccagacatcgtttcagagaaaaagcca gcaactgaagtggatcccacacattttgagaagcgcttcttaaagagaatccgtgacttg ggagagggccactttgggaaggttgagctctgcaggtatgaccctgaaggggacaataca ggagagcaggtggctgtcaaatccctgaagcctgagagtggagggaaccacatagctgat ctgaagaaggaaattgaaatcttaaggaacctctatcacgagaacattgtcaagtacaaa ggcatctgcacagaggatggaggaaatggtattaagctcatcatggaatttctgccttct ggaagccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcagtta aaatatgctgttcagatttgtaaggggatggactatttggggtcacgacagtatgttcac cgggacttagcagcaaggaatgtccttgttgaaagtgagcaccaagtgaaaattggagac ttcggtttaactaaagcaattgaaacggataaggagtactacacagtcaaggatgaccgg gacagccctgtgttctggtacgccccagaatgtctaattcagtgtaaattttatattgcc tctgacgtctggtccttcggagtgactctgcacgagctgcttacttactgtgattcagat tccagtcccatggccttgttcctgaaaatgataggccccactcacggccagatgacagta acgagacttgtgaacacattgaaagaaggaaaacgtttgccttgtcctcccaactgccca gatgaggtttatcaacttatgagaaaatgctgggaattccaaccaaataatcggacaacc ttccagaaccttattgaaggatttgaggcacttttaaaataa

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