Myotis davidii (David's myotis): 102757252 Help Entry 102757252         CDS       T02992                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism myd  Myotis davidii (David's myotis) Pathway myd00230   Purine metabolism myd01100   Metabolic pathways myd01522   Endocrine resistance myd04015   Rap1 signaling pathway myd04020   Calcium signaling pathway myd04022   cGMP-PKG signaling pathway myd04024   cAMP signaling pathway myd04062   Chemokine signaling pathway myd04072   Phospholipase D signaling pathway myd04081   Hormone signaling myd04082   Neuroactive ligand signaling myd04114   Oocyte meiosis myd04211   Longevity regulating pathway myd04213   Longevity regulating pathway - multiple species myd04261   Adrenergic signaling in cardiomyocytes myd04270   Vascular smooth muscle contraction myd04371   Apelin signaling pathway myd04540   Gap junction myd04611   Platelet activation myd04713   Circadian entrainment myd04714   Thermogenesis myd04723   Retrograde endocannabinoid signaling myd04724   Glutamatergic synapse myd04725   Cholinergic synapse myd04727   GABAergic synapse myd04740   Olfactory transduction myd04750   Inflammatory mediator regulation of TRP channels myd04911   Insulin secretion myd04912   GnRH signaling pathway myd04913   Ovarian steroidogenesis myd04914   Progesterone-mediated oocyte maturation myd04915   Estrogen signaling pathway myd04916   Melanogenesis myd04918   Thyroid hormone synthesis myd04921   Oxytocin signaling pathway myd04923   Regulation of lipolysis in adipocytes myd04925   Aldosterone synthesis and secretion myd04926   Relaxin signaling pathway myd04927   Cortisol synthesis and secretion myd04928   Parathyroid hormone synthesis, secretion and action myd04934   Cushing syndrome myd04935   Growth hormone synthesis, secretion and action myd04962   Vasopressin-regulated water reabsorption myd04970   Salivary secretion myd04971   Gastric acid secretion myd04972   Pancreatic secretion myd04976   Bile secretion myd05032   Morphine addiction myd05163   Human cytomegalovirus infection myd05166   Human T-cell leukemia virus 1 infection myd05200   Pathways in cancer myd05207   Chemical carcinogenesis - receptor activation myd05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:myd00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102757252 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102757252 (ADCY3)    04371 Apelin signaling pathway     102757252 (ADCY3)    04020 Calcium signaling pathway     102757252 (ADCY3)    04072 Phospholipase D signaling pathway     102757252 (ADCY3)    04024 cAMP signaling pathway     102757252 (ADCY3)    04022 cGMP-PKG signaling pathway     102757252 (ADCY3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102757252 (ADCY3)    04081 Hormone signaling     102757252 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102757252 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     102757252 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102757252 (ADCY3)    04062 Chemokine signaling pathway     102757252 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     102757252 (ADCY3)    04923 Regulation of lipolysis in adipocytes     102757252 (ADCY3)    04912 GnRH signaling pathway     102757252 (ADCY3)    04913 Ovarian steroidogenesis     102757252 (ADCY3)    04915 Estrogen signaling pathway     102757252 (ADCY3)    04914 Progesterone-mediated oocyte maturation     102757252 (ADCY3)    04921 Oxytocin signaling pathway     102757252 (ADCY3)    04926 Relaxin signaling pathway     102757252 (ADCY3)    04935 Growth hormone synthesis, secretion and action     102757252 (ADCY3)    04918 Thyroid hormone synthesis     102757252 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     102757252 (ADCY3)    04916 Melanogenesis     102757252 (ADCY3)    04925 Aldosterone synthesis and secretion     102757252 (ADCY3)    04927 Cortisol synthesis and secretion     102757252 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102757252 (ADCY3)    04270 Vascular smooth muscle contraction     102757252 (ADCY3)   09154 Digestive system    04970 Salivary secretion     102757252 (ADCY3)    04971 Gastric acid secretion     102757252 (ADCY3)    04972 Pancreatic secretion     102757252 (ADCY3)    04976 Bile secretion     102757252 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     102757252 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     102757252 (ADCY3)    04727 GABAergic synapse     102757252 (ADCY3)    04725 Cholinergic synapse     102757252 (ADCY3)    04723 Retrograde endocannabinoid signaling     102757252 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     102757252 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     102757252 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     102757252 (ADCY3)    04213 Longevity regulating pathway - multiple species     102757252 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     102757252 (ADCY3)    04714 Thermogenesis     102757252 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102757252 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     102757252 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102757252 (ADCY3)    05163 Human cytomegalovirus infection     102757252 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     102757252 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102757252 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102757252 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102757252 (ADCY3) Enzymes [BR:myd01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102757252 (ADCY3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N DUF3810 HNOBA Peptidase_S49_N Motif Other DBs NCBI-GeneID:  102757252 NCBI-ProteinID:  XP_006767657 LinkDB All DBs Position Un AA seq 1090 aa AA seqDB search PGFLRLTFVPASLEHLYQTYFKRQRHETLLVLVVFSPGAECAVVFSADKLAPLVVAGVGL ALDVLLFVLCRRGLLPSRVTRKVVPYLLWLLITAQIFSYLGLSFPGAHAASDTVGWQAFF VFSFFITLPLSLGPIVVISVVSCVAHTLIVGVTVAQQQQDRLKGMQLLREILANVFLYLC AIVVGIMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDM KKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSTCSAQELVKLLNELFARFDKLA AKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGV HTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGEG GSRCDYLEEKGIETYLIIASKPEVKKTASQNGLNSSALPNGAPASSKPSSPALIETKESN GSVHTSGSTSEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALL ERESAQVVKKRNTFLLSMRFMDPELETRYSVEKEKQSGAAFSCSCVVLLCAALVEIVIDP WLMTNYVTFVVGELLLLVLTVCSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFI LVMANVVDMLSCLQYYMGPINGTSGMATEDGCMENPKYYNYVAVLSLIATIMLVQVSHMV KLTLMLLVTGAVAVINLCAWRPIFDEYDRRRFQEHGVPLVALEKMQILSTPGLNGTGRLP LVPSKYTMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMQCWNGSLVTN MLPKHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNE IISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSSKEEKSDKERWQHLA DLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRM ESTGVMGNIQVVEETQAILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPAAFPNGSSV TLPHQVVDNS NT seq 3273 nt NT seq  +upstreamnt  +downstreamnt cccggcttcctgcggctgaccttcgtgcccgcgtccctggagcacctgtaccagacctac ttcaagaggcagcgccacgagaccctgctggtgctggtggtctttagcccgggggctgag tgcgccgtggtcttctccgcggacaagctggctcctctcgtggtggcgggcgtggggctg gcgttggacgtcctcctcttcgtgctgtgccggagggggctgctccccagccgggtcacc cggaaggtggtgccctacctgctgtggctgctgatcaccgcccagatcttctcctacctg ggcctgagcttccccggcgcccacgcggccagcgacacggtgggctggcaggccttcttc gtcttctccttcttcatcacgctgcccctcagcctcggccccatcgtcgtcatctcggtg gtgtcgtgtgtggcgcacacgctcattgtgggggtcaccgtggcccagcagcagcaggac aggctgaaggggatgcagttgctcagagagatcctggccaacgtcttcctctacctgtgc gccatcgtcgtgggcatcatgtcctactacatggcggaccgcaagcaccgcaaggccttc ctggaggcccgccagtcgctggaggtgaagatgaacctggaggagcagagccagcagcag gagaacctgatgctgtccatcctgcccaagcatgtggctgatgagatgctaaaggacatg aagaaagacgagagccagaaggaccagcagcagttcaacaccatgtacatgtaccgccat gagaacgtcagcatcctcttcgcggacatcgtgggcttcacccagctgtcttccacctgc agcgcccaggagctcgtgaagctgctcaatgagctctttgcccgcttcgacaagctggcg gccaaataccaccagctgcggattaagatcctgggcgactgttactactgcatctgcggc ctgcctgactaccgggaggaccacgccgtctgctccatcctcatggggctcgccatggtg gaggccatctcgtatgtgcgggagaagacgaagaccggggtggacatgcgtgtgggggtg cacacgggcactgtgctggggggcgtcctgggccagaagcgctggcagtatgacgtgtgg tccaccgacgtcactgtggccaacaagatggaggccggcggcatccccgggcgcgtgcac atctcccagagcaccctggactgcctgaaaggagagttcgacgtggagcccggcgagggg ggcagtcgctgcgattacctagaggagaagggcattgagacctacctcatcatcgcgtcc aagccagaggtgaagaaaaccgcctcccagaatggcctcaacagctcggccctgccaaac ggagcgccagcgtcctcaaagcccagctcccctgcccttatcgagaccaaggagtccaat gggagtgtccacaccagcggctccacatcggaggagcccgaggagcaggatgcccaggcc gacaacccctcgttccccaaccctcgccggaggctgcgccttcaggacctggctgatcgg gtggtggacgcctctgaggacgagcacgagctcaaccagctgctcaacgaggccctgctc gagcgggagtccgcgcaggtagtgaagaagaggaacaccttcctcctgtccatgcgcttc atggaccctgagctggagacccgctactccgtggagaaggaaaagcagagcggggccgcc ttcagctgctcctgcgtcgtgctgctgtgcgcggccctggtggagatcgtcatcgacccc tggctgatgaccaactatgtgacctttgtggttggagagcttctgcttctggtcctgacg gtctgctcgttggctgccatctttccccgggcctttcctaagaagcttgtggccttctcg acgtggattgaccggacacgttgggccaggaacacctgggccatgttagccatcttcatt ctggttatggcaaatgtcgtggacatgctgagctgcctgcaatactacatgggacccatc aatggcacctcggggatggcgacagaggatggctgcatggagaaccccaagtattacaac tatgtcgccgtgctgtccctcatcgccaccatcatgctggtgcaggtcagccacatggtg aagctcaccctcatgctgcttgtcacgggcgctgtggctgtcatcaacctctgtgcctgg cgccccatctttgatgaatatgaccgcagacgtttccaggaacacggtgttcctctggtc gccttagagaagatgcagatactctccaccccagggctcaatggcactggcaggctgccc ctggtgccttctaagtacacgatgacagtgatgatcttcgtcatgatgctgagtttctac tacttctcccgccacgtggaaaaactcgcacggacactgttcttgtggaagattgaggtc catgaccagaaggaacgtgtttacgagatgcaatgctggaatgggtccctggtcaccaac atgttgcccaaacatgtggcacgccatttcctggggtccaagaagagagatgaggagctg tatagccagtcttatgatgagattggagtcatgtttgcctccctgcccaactttgctgac ttctacaccgaggagagcatcaataatggtggcattgagtgtctgcgcttcctcaatgag atcatctcagattttgactctcttctagacaatcccaaattccgggtcatcaccaagatc aaaaccattggcagtacctatatggcagcttccggagtcacgccagatgtcaacaccaac ggctttaccagctccagcaaggaggaaaagtcagacaaggagcgctggcagcacctggct gatctggctgactttgcactagccatgaaggatacgcttacaaacatcaacaaccagtcc ttcaacaacttcatgctgcgcataggcatgaacaaaggaggggtcctggctggggtcatt ggagcccggaaaccacactacgacatctggggcaatacagtcaacgtcgccagcaggatg gagtccacaggggtcatgggtaacattcaggtggtagaagaaacacaagccatccttcga gagtacggctttcgctttgtgaggcgggggcccatctttgtgaaaggaaagggggagctg ctaacctttttcttgaaggggcgtgataagccagccgccttcccgaatggctcctctgtg accctgccccaccaggtagtagacaactcctga

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