Myotis davidii (David's myotis): 102760422
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Entry
102760422 CDS
T02992
Symbol
BRAF
Name
(RefSeq) B-Raf proto-oncogene, serine/threonine kinase
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
myd
Myotis davidii (David's myotis)
Pathway
myd01521
EGFR tyrosine kinase inhibitor resistance
myd01522
Endocrine resistance
myd04010
MAPK signaling pathway
myd04012
ErbB signaling pathway
myd04015
Rap1 signaling pathway
myd04024
cAMP signaling pathway
myd04062
Chemokine signaling pathway
myd04068
FoxO signaling pathway
myd04150
mTOR signaling pathway
myd04270
Vascular smooth muscle contraction
myd04510
Focal adhesion
myd04650
Natural killer cell mediated cytotoxicity
myd04720
Long-term potentiation
myd04722
Neurotrophin signaling pathway
myd04726
Serotonergic synapse
myd04730
Long-term depression
myd04810
Regulation of actin cytoskeleton
myd04910
Insulin signaling pathway
myd04914
Progesterone-mediated oocyte maturation
myd04928
Parathyroid hormone synthesis, secretion and action
myd04934
Cushing syndrome
myd05010
Alzheimer disease
myd05022
Pathways of neurodegeneration - multiple diseases
myd05034
Alcoholism
myd05160
Hepatitis C
myd05161
Hepatitis B
myd05200
Pathways in cancer
myd05205
Proteoglycans in cancer
myd05208
Chemical carcinogenesis - reactive oxygen species
myd05210
Colorectal cancer
myd05211
Renal cell carcinoma
myd05212
Pancreatic cancer
myd05213
Endometrial cancer
myd05214
Glioma
myd05215
Prostate cancer
myd05216
Thyroid cancer
myd05218
Melanoma
myd05219
Bladder cancer
myd05220
Chronic myeloid leukemia
myd05221
Acute myeloid leukemia
myd05223
Non-small cell lung cancer
myd05224
Breast cancer
myd05225
Hepatocellular carcinoma
myd05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
myd00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102760422 (BRAF)
04012 ErbB signaling pathway
102760422 (BRAF)
04015 Rap1 signaling pathway
102760422 (BRAF)
04068 FoxO signaling pathway
102760422 (BRAF)
04024 cAMP signaling pathway
102760422 (BRAF)
04150 mTOR signaling pathway
102760422 (BRAF)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102760422 (BRAF)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102760422 (BRAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
102760422 (BRAF)
04062 Chemokine signaling pathway
102760422 (BRAF)
09152 Endocrine system
04910 Insulin signaling pathway
102760422 (BRAF)
04914 Progesterone-mediated oocyte maturation
102760422 (BRAF)
04928 Parathyroid hormone synthesis, secretion and action
102760422 (BRAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
102760422 (BRAF)
09156 Nervous system
04726 Serotonergic synapse
102760422 (BRAF)
04720 Long-term potentiation
102760422 (BRAF)
04730 Long-term depression
102760422 (BRAF)
04722 Neurotrophin signaling pathway
102760422 (BRAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102760422 (BRAF)
05205 Proteoglycans in cancer
102760422 (BRAF)
05208 Chemical carcinogenesis - reactive oxygen species
102760422 (BRAF)
09162 Cancer: specific types
05210 Colorectal cancer
102760422 (BRAF)
05212 Pancreatic cancer
102760422 (BRAF)
05225 Hepatocellular carcinoma
102760422 (BRAF)
05226 Gastric cancer
102760422 (BRAF)
05214 Glioma
102760422 (BRAF)
05216 Thyroid cancer
102760422 (BRAF)
05221 Acute myeloid leukemia
102760422 (BRAF)
05220 Chronic myeloid leukemia
102760422 (BRAF)
05218 Melanoma
102760422 (BRAF)
05211 Renal cell carcinoma
102760422 (BRAF)
05219 Bladder cancer
102760422 (BRAF)
05215 Prostate cancer
102760422 (BRAF)
05213 Endometrial cancer
102760422 (BRAF)
05224 Breast cancer
102760422 (BRAF)
05223 Non-small cell lung cancer
102760422 (BRAF)
09172 Infectious disease: viral
05161 Hepatitis B
102760422 (BRAF)
05160 Hepatitis C
102760422 (BRAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
102760422 (BRAF)
05022 Pathways of neurodegeneration - multiple diseases
102760422 (BRAF)
09165 Substance dependence
05034 Alcoholism
102760422 (BRAF)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102760422 (BRAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102760422 (BRAF)
01522 Endocrine resistance
102760422 (BRAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
myd01001
]
102760422 (BRAF)
Enzymes [BR:
myd01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102760422 (BRAF)
Protein kinases [BR:
myd01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
102760422 (BRAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
C1_2
Pkinase_fungal
Kdo
Motif
Other DBs
NCBI-GeneID:
102760422
NCBI-ProteinID:
XP_015428170
LinkDB
All DBs
Position
Un
AA seq
712 aa
AA seq
DB search
MIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVS
SSASTDTVTSSSSSSLSVLPSSLSVFQNPTDVSRSNPKSPQKPIVRVFLPNKQRTVVPAR
CGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPL
TTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVS
KFFEHHPIPQEETSFAETTLTSGSSPSTYSSDSFGPQMLTSPSPSKSIPIPQPFRPADED
HRNQFGQRDRSSSAPNVHINTIEPVNIDEKFPEVELQDQRDLIRDQGFRSDGAPLNQLMR
CLRKYQSRTPSPLLHSVPSEIVFDFEPGPVFRGSTTGLSATPPASLPGSLTNVKALQKSP
GPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDV
AVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHH
LHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATV
KSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNIN
NRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLPNSRLY
NT seq
2139 nt
NT seq
+upstream
nt +downstream
nt
atgattaagttgacacaggaacatatagaggcgctattggacaaatttggtggggagcat
aatccaccatcaatatatctggaggcctatgaagaatacaccagcaagctagatgccctc
caacaaagagaacaacagttattggaatccctggggaatggaactgatttttctgtttct
agctctgcatcaacggacaccgttacatcttcttcctcttctagcctttcagtgctacct
tcatctctttcagtttttcaaaatcccacagatgtgtcacggagcaaccctaagtcacca
caaaaacctattgttagagtcttcctgcccaacaaacagaggacagtggtacctgcaagg
tgtggagttacagtccgggacagtctaaagaaagcattgatgatgagaggtctaatccca
gagtgttgtgctgtttacagaattcaagatggagagaagaaaccaattggatgggacact
gatatttcctggcttactggagaggaattgcatgttgaagtattggaaaatgttccactt
acaacacacaactttgtacggaaaacttttttcaccttagcattttgtgacttttgtcga
aagctgcttttccagggtttccgctgtcaaacatgtggttataaatttcaccagcgttgt
agtacagaggttccactgatgtgtgttaattatgaccaacttgatttgctgtttgtctcc
aagttttttgaacaccacccaataccacaggaggagacctcctttgcagagaccaccctt
acatctggatcatccccttccacatactcctccgattcttttgggccccaaatgctcacc
agtccgtctccttcaaaatccattccaattccacagcctttccgaccagcagatgaagat
catcgaaatcagtttggacaacgagatcggtcctcatcggctccaaatgtgcatataaac
acaatagaacctgtcaatattgatgaaaaattcccagaagtggaattacaggatcaaagg
gacttgattagagaccaagggtttcgtagtgatggagcccctttgaaccagctgatgcgc
tgtcttcggaaataccaatcccggactcccagtcccctcctacattctgtccccagtgaa
atagtgtttgattttgagcctggcccagtgttcagagggtcaactacaggtttatctgcc
accccccctgcctcattacctggctcactcactaatgtgaaagcattacagaaatcgcca
ggacctcagcgggaaagaaaatcatcttcatcctcagaagacaggaatcgaatgaaaaca
cttggtagacgggattcaagtgacgattgggagattcctgatgggcagatcacagtagga
caaagaattggttccgggtcatttgggacagtctacaagggaaagtggcatggtgatgtg
gcagtgaaaatgttgaatgtgacagcacctacacctcagcagttacaggccttcaagaat
gaagtaggagtactcaggaaaactcgacatgtaaatattctactcttcatgggctattca
acaaagccacaactggctattgttacccagtggtgtgagggctccagcttatatcaccat
ctccacatcattgagaccaaatttgagatgatcaaacttatagatattgcacggcagact
gcacagggcatggattacttacacgccaagtcaatcatccacagagacctcaagagtaat
aatatttttcttcatgaagacctcactgtaaaaataggtgactttgggctagccacagtg
aaatctcgatggagtgggtcccatcagtttgaacagttgtctggatccattctgtggatg
gcaccagaagtaatcagaatgcaagacaaaaacccttatagctttcagtcagatgtatat
gcatttgggattgttctgtatgaattgatgactggacagttaccttattcaaacatcaac
aacagggaccagataatttttatggtgggacgaggatatctatctccagatctcagtaag
gtacgaagtaactgtccaaaagccatgaagagattaatggcagaatgcctaaaaaagaaa
agagatgagagaccactaccaaattctcgcctctattga
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