Myotis davidii (David's myotis): 102762536 Help Entry 102762536         CDS       T02992                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism myd  Myotis davidii (David's myotis) Pathway myd00230   Purine metabolism myd01100   Metabolic pathways myd01522   Endocrine resistance myd04015   Rap1 signaling pathway myd04020   Calcium signaling pathway myd04022   cGMP-PKG signaling pathway myd04024   cAMP signaling pathway myd04062   Chemokine signaling pathway myd04072   Phospholipase D signaling pathway myd04081   Hormone signaling myd04082   Neuroactive ligand signaling myd04114   Oocyte meiosis myd04211   Longevity regulating pathway myd04213   Longevity regulating pathway - multiple species myd04261   Adrenergic signaling in cardiomyocytes myd04270   Vascular smooth muscle contraction myd04371   Apelin signaling pathway myd04540   Gap junction myd04611   Platelet activation myd04713   Circadian entrainment myd04714   Thermogenesis myd04723   Retrograde endocannabinoid signaling myd04724   Glutamatergic synapse myd04725   Cholinergic synapse myd04727   GABAergic synapse myd04742   Taste transduction myd04750   Inflammatory mediator regulation of TRP channels myd04911   Insulin secretion myd04912   GnRH signaling pathway myd04913   Ovarian steroidogenesis myd04914   Progesterone-mediated oocyte maturation myd04915   Estrogen signaling pathway myd04916   Melanogenesis myd04918   Thyroid hormone synthesis myd04921   Oxytocin signaling pathway myd04923   Regulation of lipolysis in adipocytes myd04925   Aldosterone synthesis and secretion myd04926   Relaxin signaling pathway myd04927   Cortisol synthesis and secretion myd04928   Parathyroid hormone synthesis, secretion and action myd04934   Cushing syndrome myd04935   Growth hormone synthesis, secretion and action myd04970   Salivary secretion myd04971   Gastric acid secretion myd04972   Pancreatic secretion myd04976   Bile secretion myd05032   Morphine addiction myd05163   Human cytomegalovirus infection myd05166   Human T-cell leukemia virus 1 infection myd05200   Pathways in cancer myd05207   Chemical carcinogenesis - receptor activation myd05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:myd00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102762536 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102762536 (ADCY4)    04371 Apelin signaling pathway     102762536 (ADCY4)    04020 Calcium signaling pathway     102762536 (ADCY4)    04072 Phospholipase D signaling pathway     102762536 (ADCY4)    04024 cAMP signaling pathway     102762536 (ADCY4)    04022 cGMP-PKG signaling pathway     102762536 (ADCY4)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102762536 (ADCY4)    04081 Hormone signaling     102762536 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102762536 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     102762536 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102762536 (ADCY4)    04062 Chemokine signaling pathway     102762536 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     102762536 (ADCY4)    04923 Regulation of lipolysis in adipocytes     102762536 (ADCY4)    04912 GnRH signaling pathway     102762536 (ADCY4)    04913 Ovarian steroidogenesis     102762536 (ADCY4)    04915 Estrogen signaling pathway     102762536 (ADCY4)    04914 Progesterone-mediated oocyte maturation     102762536 (ADCY4)    04921 Oxytocin signaling pathway     102762536 (ADCY4)    04926 Relaxin signaling pathway     102762536 (ADCY4)    04935 Growth hormone synthesis, secretion and action     102762536 (ADCY4)    04918 Thyroid hormone synthesis     102762536 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     102762536 (ADCY4)    04916 Melanogenesis     102762536 (ADCY4)    04925 Aldosterone synthesis and secretion     102762536 (ADCY4)    04927 Cortisol synthesis and secretion     102762536 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102762536 (ADCY4)    04270 Vascular smooth muscle contraction     102762536 (ADCY4)   09154 Digestive system    04970 Salivary secretion     102762536 (ADCY4)    04971 Gastric acid secretion     102762536 (ADCY4)    04972 Pancreatic secretion     102762536 (ADCY4)    04976 Bile secretion     102762536 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     102762536 (ADCY4)    04727 GABAergic synapse     102762536 (ADCY4)    04725 Cholinergic synapse     102762536 (ADCY4)    04723 Retrograde endocannabinoid signaling     102762536 (ADCY4)   09157 Sensory system    04742 Taste transduction     102762536 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     102762536 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     102762536 (ADCY4)    04213 Longevity regulating pathway - multiple species     102762536 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     102762536 (ADCY4)    04714 Thermogenesis     102762536 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102762536 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     102762536 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102762536 (ADCY4)    05163 Human cytomegalovirus infection     102762536 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     102762536 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102762536 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102762536 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102762536 (ADCY4) Enzymes [BR:myd01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102762536 (ADCY4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 Motif Other DBs NCBI-GeneID:  102762536 NCBI-ProteinID:  XP_006760892 UniProt:  L5M406 LinkDB All DBs Position Un AA seq 1077 aa AA seqDB search MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLCALLALLAVAWASGRELAADPG FLTTVLCALGGFSLLLGLASCEQRLQRWTRPLSGLVWAALLALGHGFLFTGGVVSAWDQV SFFLFVIFTTYAMLPLGMRDATAAGLTSSLSHLLALGLYLGPQLDSRPALLPQLAANAVL FLCGNVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG AYAVEDAAIEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTR YLESWGAAKPFAHLSHVESPVSTSTPLPEKTLASFSPQWSLDRSRTPRGLDDEMDTGDAK FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSALPAFKYYAACTFLVFLSNFI IQMLVTNRPPALAITYSITFLLFFLLLFVCFSEHLTRCVLKGPKMLHWLPALSGLVATRP GLRIALGSATILLIFAMAITSLFFLPAASNCPFRATNVSSMAFNLSWELPGSLPLISIPY SMHCCVLGFLSCSLFLHMSFELKLLLLLLWLVASCCLFLHSHAWLSDCLVARLYLGSLDS RPGVLKEPKLMGAISFFIFFFTLLALARQNEYYCRLDFLWKKKLRQEREETETMENLTRL LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLR LLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMV EFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST GVLGKIQVTEETARALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLIRVGPPSAALG NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atggcccgactcttcagtccccggccgccacccagcgaagacctcttctatgagacctac tacagcctgagccaacagtacccgctcctgctgctgctgctggtgatcgtgctctgcgcg ctcctggcgctgctggccgtcgcctgggccagcggcagggagctggccgcagacccgggc ttcctgaccacagtgctgtgcgcgctgggcggcttctcgctgctgctgggcctggcttcc tgcgagcagcggctgcagcgctggacgcgtccgctctcgggcctcgtgtgggcagcgctg cttgcgttaggccatggcttcctattcactgggggcgtggtgagcgcctgggaccaggtg tcctttttcctctttgtcatcttcactacctacgccatgttgcctctgggcatgcgggac gccacagctgcgggcctcacctcctccctctcacacctgctggcactcgggctgtatctt ggacctcaactagactcaagacctgcgctgctgccgcagttggcagcaaacgcggtgttg ttcctgtgcgggaatgtggcgggagcgtaccacaaggcgctgatggagcgcgcgctgcgc gccaccttccgcgaggcgctcagctccttgcactcacgccggcggctggacaccgagaag aagcaccaggaacaccttctcttgtccatccttcctgcctacttggcccgagagatgaag gcagagatcatggcacggctgcaggctggacaggggtcaaggccggagagcaccaacaac ttccacagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg ggcttcacacggctggccagtgagtgctccccgaaggagctggtgctcatgctcaatgag ctctttggcaaatttgaccagatcgccaaggagcatgaatgcatgcggatcaagatcctg ggagactgttactactgtgtctccgggctgcccctctccttaccagaccacgccatcaac tgcgtgcgcatggggctggacatgtgccgggccatcaggaaactacgagcagccaccggt gtggacatcaacatgcgcgtgggtgtgcactcgggcagcgtgctctgtggagtcatcggg ctgcagaagtggcagtatgatgtctggtcccatgatgtcacactggccaaccacatggag gcaggtggcgtgccaggacgagtacatatcaccggggctaccctggccctgctggcagga gcttacgctgtggaggatgcagccatagaacaccgggacccataccttcgggagctaggg gagcctacgtacctggtcatcgatccccgggctgaggaagaggatgagaagggcactgca ggagggttgctgtcctctcttgagggccccaagatgcgtccatcactgctgatgacccgc tacctggaatcctggggtgcagccaagccttttgcccacctgagccacgtagagagccct gtgtccacctccactcctctcccggagaagaccctggcttccttcagcccccagtggagc ctggaccggagccgtacaccccggggactagatgatgaaatggacactggggatgccaag ttcttccaggtcatcgaacagctcaactctcagaaacagtggaagcagtcaaaggacttc aacccactgacactttacttccgagagaaggaaatggagaaagagtatcgactctctgca ctccctgcctttaaatactatgcagcctgcacattcctggtttttctctccaacttcatc atccagatgctggtgacaaacaggcccccagctctggccatcacctatagcatcaccttc ctcctcttcttcctcctcctcttcgtctgcttctcagagcacctgacgaggtgcgtcttg aaaggccccaagatgctgcactggctgcccgcattgtctggcctggtggccacacgtcct ggactgcgaattgccctgggcagtgccaccatcctcctcatctttgccatggccattacc agcctgttcttcttaccagcagcatcaaactgcccttttcgggctaccaatgtgtcctcc atggctttcaacctctcctgggagctccctgggtccctgcctctcatcagtattccatac tccatgcactgctgcgtgctgggtttcctctcctgctccctctttctgcacatgagcttc gaactgaagctgctgctgctcctgctatggctggtggcctcctgctgcctcttcctgcac tcccatgcctggctgtccgactgcctcgtcgcccgcctctatctgggctccttggactcc aggccaggggtgctgaaggagcccaaactgatgggagctatctccttcttcatcttcttc ttcacactccttgccttggctcggcagaatgaatattactgccgcctggatttcctgtgg aagaagaagctgaggcaggagcgggaggaaacagagacaatggagaatctgactcggctg ctcttggagaacgtgctgcctgcacacgtggccccccagtttattggccagaaccggcgc aatgaggacctctaccaccagtcctatgagtgtgtctgtgtcctcttcgcctcagtccca gacttcaaggagttttactctgaatccaacatcaaccacgaggggctagagtgtctgcgc ctgctcaatgagatcattgctgattttgatgagctgctctctaagcccaagttcagtggg gtggagaagatcaaaaccatcggcagcacctacatggcagctactggcttaaatgccacc tctggacaggatgcacagcaggatgctgagcgaagctgcagccacctcggcaccatggtg gaatttgcagtggcccttgggtctaagctggacgttatcaacaagcactcattcaacaac ttccgcttgcgtgtggggctaaaccatggaccagtagtggccggagtgataggagcccag aaaccacaatatgacatctggggcaatacggtgaatgtggccagtcgcatggagagtaca ggagtcctgggcaagatacaagtgactgaggagacagcccgggccctgcagtccttaggc tacacctgctacagcaggggcgttatcaaggtcaaaggcaaagggcagctgtgtacctac ttcctcaacacagatttgataagagttggacctccctcagctgccctaggctga

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