Myotis davidii (David's myotis): 102766123 Help Entry 102766123         CDS       T02992                                  Symbol ADCY6 Name (RefSeq) adenylate cyclase 6   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism myd  Myotis davidii (David's myotis) Pathway myd00230   Purine metabolism myd01100   Metabolic pathways myd01522   Endocrine resistance myd04015   Rap1 signaling pathway myd04022   cGMP-PKG signaling pathway myd04024   cAMP signaling pathway myd04062   Chemokine signaling pathway myd04072   Phospholipase D signaling pathway myd04081   Hormone signaling myd04082   Neuroactive ligand signaling myd04114   Oocyte meiosis myd04211   Longevity regulating pathway myd04213   Longevity regulating pathway - multiple species myd04261   Adrenergic signaling in cardiomyocytes myd04270   Vascular smooth muscle contraction myd04371   Apelin signaling pathway myd04540   Gap junction myd04611   Platelet activation myd04713   Circadian entrainment myd04714   Thermogenesis myd04723   Retrograde endocannabinoid signaling myd04724   Glutamatergic synapse myd04725   Cholinergic synapse myd04727   GABAergic synapse myd04742   Taste transduction myd04750   Inflammatory mediator regulation of TRP channels myd04911   Insulin secretion myd04912   GnRH signaling pathway myd04913   Ovarian steroidogenesis myd04914   Progesterone-mediated oocyte maturation myd04915   Estrogen signaling pathway myd04916   Melanogenesis myd04918   Thyroid hormone synthesis myd04921   Oxytocin signaling pathway myd04923   Regulation of lipolysis in adipocytes myd04924   Renin secretion myd04925   Aldosterone synthesis and secretion myd04926   Relaxin signaling pathway myd04927   Cortisol synthesis and secretion myd04928   Parathyroid hormone synthesis, secretion and action myd04934   Cushing syndrome myd04935   Growth hormone synthesis, secretion and action myd04961   Endocrine and other factor-regulated calcium reabsorption myd04962   Vasopressin-regulated water reabsorption myd04970   Salivary secretion myd04971   Gastric acid secretion myd04972   Pancreatic secretion myd04976   Bile secretion myd05032   Morphine addiction myd05163   Human cytomegalovirus infection myd05166   Human T-cell leukemia virus 1 infection myd05200   Pathways in cancer myd05207   Chemical carcinogenesis - receptor activation myd05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:myd00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102766123 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102766123 (ADCY6)    04371 Apelin signaling pathway     102766123 (ADCY6)    04072 Phospholipase D signaling pathway     102766123 (ADCY6)    04024 cAMP signaling pathway     102766123 (ADCY6)    04022 cGMP-PKG signaling pathway     102766123 (ADCY6)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102766123 (ADCY6)    04081 Hormone signaling     102766123 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102766123 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     102766123 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102766123 (ADCY6)    04062 Chemokine signaling pathway     102766123 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     102766123 (ADCY6)    04923 Regulation of lipolysis in adipocytes     102766123 (ADCY6)    04912 GnRH signaling pathway     102766123 (ADCY6)    04913 Ovarian steroidogenesis     102766123 (ADCY6)    04915 Estrogen signaling pathway     102766123 (ADCY6)    04914 Progesterone-mediated oocyte maturation     102766123 (ADCY6)    04921 Oxytocin signaling pathway     102766123 (ADCY6)    04926 Relaxin signaling pathway     102766123 (ADCY6)    04935 Growth hormone synthesis, secretion and action     102766123 (ADCY6)    04918 Thyroid hormone synthesis     102766123 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     102766123 (ADCY6)    04916 Melanogenesis     102766123 (ADCY6)    04924 Renin secretion     102766123 (ADCY6)    04925 Aldosterone synthesis and secretion     102766123 (ADCY6)    04927 Cortisol synthesis and secretion     102766123 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102766123 (ADCY6)    04270 Vascular smooth muscle contraction     102766123 (ADCY6)   09154 Digestive system    04970 Salivary secretion     102766123 (ADCY6)    04971 Gastric acid secretion     102766123 (ADCY6)    04972 Pancreatic secretion     102766123 (ADCY6)    04976 Bile secretion     102766123 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     102766123 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     102766123 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     102766123 (ADCY6)    04727 GABAergic synapse     102766123 (ADCY6)    04725 Cholinergic synapse     102766123 (ADCY6)    04723 Retrograde endocannabinoid signaling     102766123 (ADCY6)   09157 Sensory system    04742 Taste transduction     102766123 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     102766123 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     102766123 (ADCY6)    04213 Longevity regulating pathway - multiple species     102766123 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     102766123 (ADCY6)    04714 Thermogenesis     102766123 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102766123 (ADCY6)    05207 Chemical carcinogenesis - receptor activation     102766123 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102766123 (ADCY6)    05163 Human cytomegalovirus infection     102766123 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     102766123 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102766123 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102766123 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102766123 (ADCY6) Enzymes [BR:myd01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102766123 (ADCY6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  102766123 NCBI-ProteinID:  XP_006755545 UniProt:  L5MDL9 LinkDB All DBs Position Un AA seq 1166 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQKRPRHRTRTSGFCAPRYMSCLRDAQPPSPTPEAPP QCPWQEEAFIRRGGPSKGTELGLRAVALGFEDPETTVAVGVAEVAPDVAPRSRRSCWRRL VQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPARPQPAYVA LLACAAVLFVVLMVVCNQHSFRQDSMWVVSYVVLGILAAVQVGGALAANPHSPSAGLWCP VFFVYITYTLLPIRMRAAVFSGLGLSILHLILAWQLNRGDAFLWKQLGANMLLFLCTNVI GICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKK EDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLR IKILGDCYYCVSGLPEARTDHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHC GVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGHGGERNAYL KEQHIETFLILGTSQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFRQM GIDDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYS QKVDPRFGAYVACALLVFCFICFIQLLIFPHSTLMLGLYVGIFLLLLITVLICAVYSCGS IFPEALQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTPIRTCAARILNVTPA DVTACHLQQLNYSLGLDTPLCEGTAPTCSFPEYFVGNMLLSLLASSVFLHISSIGKLAMI FVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETIDGLDCPAAGRVALKYMTPVIL LVFALALYLHAQQVESTARLDFLWKLQATGEKEDMEELQAYNRRLLHNILPKDVAAHFLA RERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEE RFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQ MKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQ LECRGVVKVKGKGEMTTYFLNGGPSS NT seq 3501 nt NT seq  +upstreamnt  +downstreamnt atgtcatggtttagtggccttctggtgcccaaagtggatgaacggaaaacagcctggggt gaacgcaatgggcagaagcgccctcgtcacaggactcggaccagtggcttctgcgcaccc cgctacatgagctgcctccgggatgcacagccacccagccccacccctgaagcccctcct cagtgcccctggcaggaggaggccttcatccggagggggggccctagcaagggcactgag ttggggctgcgggccgtggccctgggctttgaggaccctgagacaacagtggcggttggg gtggctgaggtggcacccgatgtagcacccaggagcaggcgatcctgctggcgccggctg gtgcaggtgttccagtccaagcagttccgctcagccaagctggagcgcctgtaccagcgg tacttcttccagatgaaccagagcagcctcacgctgctgatggcggtgctcgtgctgctc accgctgtgctgctggccttccatgctgcgcccgcccgccctcagcctgcctacgtggcc ctgctggcctgcgcggccgtcctctttgtggtgctcatggtggtgtgcaaccaacacagc ttccgccaggactccatgtgggtagtgagctacgtggtgctgggcatcctggcggctgtg caggttgggggcgccttggcagccaacccccacagcccgtctgcgggcctctggtgcccc gtgttctttgtctacatcacctacacgctcctacccatccgcatgcgggcagctgtcttc agtggcctgggcctctccatcttgcatttgatcttggcctggcaactcaaccgtggtgat gccttcctctggaagcagctcggtgccaacatgctgctgttcctctgcaccaacgtcatt ggcatctgcacacactacccggctgaggtgtctcagcgacaggcctttcaggagactcgt ggctacatccaagcccggttgcacctgcagcatgagaaccggcagcaggagcggctactg ctatcagtgttgccccagcatgttgccatggagatgaaagaagacattaacacaaagaaa gaagacatgatgttccataagatctacatccagaagcatgacaacgtcagcatcctgttt gcggacatcgaaggtttcaccagcctggcatcccagtgcactgcacaggagctggtcatg accctgaatgagctgtttgcgcggtttgacaagctggctgcggaaaatcactgcctgagg atcaagatcttaggggactgttactactgtgtgtcgggattgccagaggcccggacagac catgcccactgctgtgtggagatgggggtagacatgatcgaggccatctcgctggtgcgt gaggtgacaggtgtgaacgtgaacatgcgcgtgggcatccacagcgggcgcgtgcactgc ggtgtcctcggcctgcggaaatggcagttcgatgtgtggtccaatgacgtgactctggcc aaccacatggaggcggggggccgggccggccgcatccacatcactcgggccacgctgcag tacctgaacggggactacgaggtggagccaggccatggcggtgagcgcaacgcatacctc aaggagcagcacattgagaccttcctcatcctgggcaccagccagaaacggaaagaggag aaggccatgctggccaagctgcagcggacacgggccaactccatggaagggctgatgcca cgctgggtgcccgaccgagccttctcccggaccaaggactctaaggcttttcgccagatg ggcattgatgattccagcaaagacaaccggggcgctcaagacgccctgaaccctgaggat gaggtagacgagttcctgggccgtgccatcgatgcccgcagcatcgatcagctgcgcaag gaccacgtgcgccgattcctgctcaccttccagagagaggatcttgaaaagaagtactcg cagaaagtggatccccgtttcggagcctacgtggcctgtgccctgttggtcttctgcttc atctgcttcatccagctcctcatcttcccacactcaacgctgatgcttgggctctatgtc ggcatcttcctgctgctgctgatcacagtgctgatttgcgccgtgtactcctgtggctct atcttccctgaggccctgcaacgcctgtcacgcagcattgtccgctcgcgggcacacagc actgcagttggcatcttttcagtcctgcttgtgttcacctccgccatcgccaacatgttc acctgcaaccacacccccatccgaacctgcgcagcaaggatactgaatgtgacacctgcc gacgtcaccgcctgccacctgcagcagctcaattactctctgggtcttgatactcccctg tgcgagggcactgcccccacctgcagcttccctgagtacttcgtcgggaacatgctgctg agtctgttggccagctctgtcttcctgcacatcagtagcatcgggaagctggccatgatc tttgtcctggggctcatctacttggtgctgcttctgctgggccccccagccaccatcttt gacaactatgacctgctgcttggcgtccatggcttggcttcttccaatgagaccatcgat gggctggactgcccagctgcagggagggtggcgctcaaatacatgacccccgtgattctg ctggtgtttgcgctggcgctgtatctgcatgctcagcaggtggaatcgactgcccgcctg gacttcctctggaaactgcaggccacaggggagaaggaggatatggaggagctccaggcc tacaaccggaggctgctgcacaacattctgcccaaggacgtggccgcccactttctggcc cgggagcgccggaacgatgagctctactaccagtcttgtgagtgtgtggctgtcatgttt gcctccattgccaacttctctgagttctacgtggagctggaggcaaacaatgagggcgtg gagtgcctgcggctgctcaacgagatcatcgctgactttgatgagatcatcagtgaggag cggttccggcagctggagaagatcaagacgattggcagcacctacatggcggcctcgggg ctgaatgccagcacctatgaccaggtgggccgctcccacatcactgccctcgcagactat gccatgcggctcatggagcagatgaagcacatcaatgagcactccttcaacaatttccag atgaagattggactgaacatgggccccgttgtggcaggcgtcattggggctcggaagcca cagtatgacatctgggggaacacagtgaatgtctctagccggatggacagcacaggggtt cctgaccgaatccaggtgaccacggacctgtaccaggttctagctgccaagggctaccag ctggagtgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacttacttcctc aatgggggtcccagcagttag

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