Myotis davidii (David's myotis): 102773065 Help Entry 102773065         CDS       T02992                                  Symbol AKT2 Name (RefSeq) AKT serine/threonine kinase 2   KO K04456   RAC serine/threonine-protein kinase [EC:2.7.11.1] Organism myd  Myotis davidii (David's myotis) Pathway myd01521   EGFR tyrosine kinase inhibitor resistance myd01522   Endocrine resistance myd01524   Platinum drug resistance myd04010   MAPK signaling pathway myd04012   ErbB signaling pathway myd04014   Ras signaling pathway myd04015   Rap1 signaling pathway myd04022   cGMP-PKG signaling pathway myd04024   cAMP signaling pathway myd04062   Chemokine signaling pathway myd04066   HIF-1 signaling pathway myd04068   FoxO signaling pathway myd04071   Sphingolipid signaling pathway myd04072   Phospholipase D signaling pathway myd04140   Autophagy - animal myd04150   mTOR signaling pathway myd04151   PI3K-Akt signaling pathway myd04152   AMPK signaling pathway myd04210   Apoptosis myd04211   Longevity regulating pathway myd04213   Longevity regulating pathway - multiple species myd04218   Cellular senescence myd04261   Adrenergic signaling in cardiomyocytes myd04370   VEGF signaling pathway myd04371   Apelin signaling pathway myd04380   Osteoclast differentiation myd04510   Focal adhesion myd04550   Signaling pathways regulating pluripotency of stem cells myd04611   Platelet activation myd04613   Neutrophil extracellular trap formation myd04620   Toll-like receptor signaling pathway myd04625   C-type lectin receptor signaling pathway myd04630   JAK-STAT signaling pathway myd04660   T cell receptor signaling pathway myd04662   B cell receptor signaling pathway myd04664   Fc epsilon RI signaling pathway myd04666   Fc gamma R-mediated phagocytosis myd04668   TNF signaling pathway myd04722   Neurotrophin signaling pathway myd04725   Cholinergic synapse myd04728   Dopaminergic synapse myd04810   Regulation of actin cytoskeleton myd04910   Insulin signaling pathway myd04914   Progesterone-mediated oocyte maturation myd04915   Estrogen signaling pathway myd04917   Prolactin signaling pathway myd04919   Thyroid hormone signaling pathway myd04920   Adipocytokine signaling pathway myd04922   Glucagon signaling pathway myd04923   Regulation of lipolysis in adipocytes myd04926   Relaxin signaling pathway myd04929   GnRH secretion myd04931   Insulin resistance myd04932   Non-alcoholic fatty liver disease myd04933   AGE-RAGE signaling pathway in diabetic complications myd04935   Growth hormone synthesis, secretion and action myd04936   Alcoholic liver disease myd04973   Carbohydrate digestion and absorption myd05010   Alzheimer disease myd05017   Spinocerebellar ataxia myd05132   Salmonella infection myd05135   Yersinia infection myd05142   Chagas disease myd05145   Toxoplasmosis myd05152   Tuberculosis myd05160   Hepatitis C myd05161   Hepatitis B myd05162   Measles myd05163   Human cytomegalovirus infection myd05164   Influenza A myd05165   Human papillomavirus infection myd05166   Human T-cell leukemia virus 1 infection myd05167   Kaposi sarcoma-associated herpesvirus infection myd05168   Herpes simplex virus 1 infection myd05169   Epstein-Barr virus infection myd05170   Human immunodeficiency virus 1 infection myd05200   Pathways in cancer myd05205   Proteoglycans in cancer myd05207   Chemical carcinogenesis - receptor activation myd05208   Chemical carcinogenesis - reactive oxygen species myd05210   Colorectal cancer myd05211   Renal cell carcinoma myd05212   Pancreatic cancer myd05213   Endometrial cancer myd05214   Glioma myd05215   Prostate cancer myd05218   Melanoma myd05220   Chronic myeloid leukemia myd05221   Acute myeloid leukemia myd05222   Small cell lung cancer myd05223   Non-small cell lung cancer myd05224   Breast cancer myd05225   Hepatocellular carcinoma myd05226   Gastric cancer myd05230   Central carbon metabolism in cancer myd05231   Choline metabolism in cancer myd05235   PD-L1 expression and PD-1 checkpoint pathway in cancer myd05415   Diabetic cardiomyopathy myd05417   Lipid and atherosclerosis myd05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:myd00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102773065 (AKT2)    04012 ErbB signaling pathway     102773065 (AKT2)    04014 Ras signaling pathway     102773065 (AKT2)    04015 Rap1 signaling pathway     102773065 (AKT2)    04370 VEGF signaling pathway     102773065 (AKT2)    04371 Apelin signaling pathway     102773065 (AKT2)    04630 JAK-STAT signaling pathway     102773065 (AKT2)    04668 TNF signaling pathway     102773065 (AKT2)    04066 HIF-1 signaling pathway     102773065 (AKT2)    04068 FoxO signaling pathway     102773065 (AKT2)    04072 Phospholipase D signaling pathway     102773065 (AKT2)    04071 Sphingolipid signaling pathway     102773065 (AKT2)    04024 cAMP signaling pathway     102773065 (AKT2)    04022 cGMP-PKG signaling pathway     102773065 (AKT2)    04151 PI3K-Akt signaling pathway     102773065 (AKT2)    04152 AMPK signaling pathway     102773065 (AKT2)    04150 mTOR signaling pathway     102773065 (AKT2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102773065 (AKT2)   09143 Cell growth and death    04210 Apoptosis     102773065 (AKT2)    04218 Cellular senescence     102773065 (AKT2)   09144 Cellular community - eukaryotes    04510 Focal adhesion     102773065 (AKT2)    04550 Signaling pathways regulating pluripotency of stem cells     102773065 (AKT2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     102773065 (AKT2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102773065 (AKT2)    04613 Neutrophil extracellular trap formation     102773065 (AKT2)    04620 Toll-like receptor signaling pathway     102773065 (AKT2)    04625 C-type lectin receptor signaling pathway     102773065 (AKT2)    04660 T cell receptor signaling pathway     102773065 (AKT2)    04662 B cell receptor signaling pathway     102773065 (AKT2)    04664 Fc epsilon RI signaling pathway     102773065 (AKT2)    04666 Fc gamma R-mediated phagocytosis     102773065 (AKT2)    04062 Chemokine signaling pathway     102773065 (AKT2)   09152 Endocrine system    04910 Insulin signaling pathway     102773065 (AKT2)    04922 Glucagon signaling pathway     102773065 (AKT2)    04923 Regulation of lipolysis in adipocytes     102773065 (AKT2)    04920 Adipocytokine signaling pathway     102773065 (AKT2)    04929 GnRH secretion     102773065 (AKT2)    04915 Estrogen signaling pathway     102773065 (AKT2)    04914 Progesterone-mediated oocyte maturation     102773065 (AKT2)    04917 Prolactin signaling pathway     102773065 (AKT2)    04926 Relaxin signaling pathway     102773065 (AKT2)    04935 Growth hormone synthesis, secretion and action     102773065 (AKT2)    04919 Thyroid hormone signaling pathway     102773065 (AKT2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102773065 (AKT2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     102773065 (AKT2)   09156 Nervous system    04725 Cholinergic synapse     102773065 (AKT2)    04728 Dopaminergic synapse     102773065 (AKT2)    04722 Neurotrophin signaling pathway     102773065 (AKT2)   09158 Development and regeneration    04380 Osteoclast differentiation     102773065 (AKT2)   09149 Aging    04211 Longevity regulating pathway     102773065 (AKT2)    04213 Longevity regulating pathway - multiple species     102773065 (AKT2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102773065 (AKT2)    05205 Proteoglycans in cancer     102773065 (AKT2)    05207 Chemical carcinogenesis - receptor activation     102773065 (AKT2)    05208 Chemical carcinogenesis - reactive oxygen species     102773065 (AKT2)    05230 Central carbon metabolism in cancer     102773065 (AKT2)    05231 Choline metabolism in cancer     102773065 (AKT2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102773065 (AKT2)   09162 Cancer: specific types    05210 Colorectal cancer     102773065 (AKT2)    05212 Pancreatic cancer     102773065 (AKT2)    05225 Hepatocellular carcinoma     102773065 (AKT2)    05226 Gastric cancer     102773065 (AKT2)    05214 Glioma     102773065 (AKT2)    05221 Acute myeloid leukemia     102773065 (AKT2)    05220 Chronic myeloid leukemia     102773065 (AKT2)    05218 Melanoma     102773065 (AKT2)    05211 Renal cell carcinoma     102773065 (AKT2)    05215 Prostate cancer     102773065 (AKT2)    05213 Endometrial cancer     102773065 (AKT2)    05224 Breast cancer     102773065 (AKT2)    05222 Small cell lung cancer     102773065 (AKT2)    05223 Non-small cell lung cancer     102773065 (AKT2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102773065 (AKT2)    05170 Human immunodeficiency virus 1 infection     102773065 (AKT2)    05161 Hepatitis B     102773065 (AKT2)    05160 Hepatitis C     102773065 (AKT2)    05164 Influenza A     102773065 (AKT2)    05162 Measles     102773065 (AKT2)    05168 Herpes simplex virus 1 infection     102773065 (AKT2)    05163 Human cytomegalovirus infection     102773065 (AKT2)    05167 Kaposi sarcoma-associated herpesvirus infection     102773065 (AKT2)    05169 Epstein-Barr virus infection     102773065 (AKT2)    05165 Human papillomavirus infection     102773065 (AKT2)   09171 Infectious disease: bacterial    05132 Salmonella infection     102773065 (AKT2)    05135 Yersinia infection     102773065 (AKT2)    05152 Tuberculosis     102773065 (AKT2)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     102773065 (AKT2)    05142 Chagas disease     102773065 (AKT2)   09164 Neurodegenerative disease    05010 Alzheimer disease     102773065 (AKT2)    05017 Spinocerebellar ataxia     102773065 (AKT2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102773065 (AKT2)    05418 Fluid shear stress and atherosclerosis     102773065 (AKT2)    05415 Diabetic cardiomyopathy     102773065 (AKT2)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     102773065 (AKT2)    04932 Non-alcoholic fatty liver disease     102773065 (AKT2)    04931 Insulin resistance     102773065 (AKT2)    04933 AGE-RAGE signaling pathway in diabetic complications     102773065 (AKT2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102773065 (AKT2)    01524 Platinum drug resistance     102773065 (AKT2)    01522 Endocrine resistance     102773065 (AKT2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:myd01001]     102773065 (AKT2) Enzymes [BR:myd01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      102773065 (AKT2) Protein kinases [BR:myd01001]  Serine/threonine kinases: AGC group   AKT/PKB family    102773065 (AKT2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PH Kinase-like Pkinase_C PH_20 PH_11 ABC1 Seadorna_VP7 Motif Other DBs NCBI-GeneID:  102773065 NCBI-ProteinID:  XP_006763729 LinkDB All DBs Position Un AA seq 481 aa AA seqDB search MNEVSVIKEGWLHKRGEYIKTWRPRYFLMKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRGPGEDPM EYKCGSPSDSSAAEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK KLPPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGSLDLDQRTHFPQFSYSASIR E NT seq 1446 nt NT seq  +upstreamnt  +downstreamnt atgaacgaggtgtctgtcatcaaagaaggctggctccacaagcgtggtgaatacatcaag acgtggaggccccggtacttcctgatgaagagtgatggttccttcattggctataaggag cggcctgaggcccctgaccagacgctgccccctttaaacaacttctccgttgcggaatgc cagctgatgaagaccgagagaccgcggcccaacacattcgtcatacgctgcttgcagtgg accacagtcatcgagaggaccttccacgtagactctcccgatgagagggaagagtggatg cgggccatccagatggtcgccaatagcctcaagcagcggggcccaggtgaggaccccatg gaatacaagtgtggctcccctagtgattcttctgcggctgaagagatggaagtggccgtt agcaaggcacgggccaaggtgaccatgaatgactttgactatctcaagctcctcggcaag ggcaccttcggcaaagtcatcctggtgcgggagaaggccaccggccgctactacgccatg aagatcctacggaaggaggtgatcatcgccaaggacgaagtcgcccacacagtcaccgag agccgggtcctccagaacaccaggcaccccttcctcactgcgctgaagtacgccttccag acccacgaccgcctgtgcttcgtgatggagtacgccaacggtggggagctgttcttccac ctgtcccgggagcgcgtcttcacggaggagcgggcccgcttttatggtgcagagatcgtc tcggccctggagtacctgcactcgagggatgtggtgtaccgcgacatcaagctggaaaac ctcatgctggacaaagacggccacatcaagatcactgactttggcctgtgcaaagagggc atcagtgatggggccaccatgaagaccttctgcgggacccccgagtatctggcacccgag gtcctggaggacaacgactacggccgggctgtggactggtgggggctgggcgtggtcatg tacgagatgatgtgcggccgcctgcccttctacaaccaggaccacgagcgcctcttcgag ctcatcctcatggaggagatccgcttcccgcgcacgctcagccccgaggccaagtccctg ctggctgggctgcttaagaaggaccccaagcagaggctcggcggggggcccagcgatgcc aaggaggtcatggagcacaggttcttcctcagcatcaactggcaggatgtggtacagaag aagctcccaccacccttcaaacctcaggtcacatccgaggtcgacaccaggtacttcgat gatgagttcactgcccagtccatcacaatcacacccccggaccgctatgacagcctgggc tctctggacctggaccagcggactcacttcccccagttctcctactcggccagcatccgc gagtga

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