Mycolicibacterium sp. HK-90: QU592_18580
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Entry
QU592_18580 CDS
T11081
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
myh Mycolicibacterium sp. HK-90
Pathway
myh00300
Lysine biosynthesis
myh00550
Peptidoglycan biosynthesis
myh01100
Metabolic pathways
myh01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
myh00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
QU592_18580 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
QU592_18580 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
QU592_18580 (murF)
Enzymes [BR:
myh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
QU592_18580 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
WKG01284
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Position
complement(3857627..3859180)
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AA seq
517 aa
AA seq
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MIEMTVARIAEIVGGELADITAEQAAATRVTGTVEFDSRAIGPGGLFLALPGARADGHDF
AAAAVASGAPVVLAARPVGVPAIVVRPEPGAADAASGALEFDTDGSGAAVLAALAKLAAA
VAAELVADGLTIIGVTGSSGKTSTKDLLAAVLAPLGQVIAPPGSFNNELGHPWTVLRATP
ETDYLILEMSARHPGNIAALAAIAPPQIAVVLNVGTAHLGEFGSREAIANTKAELPQAVP
ASGVVILNVDDTAVAAMADATAARVVRVSREPGAQVDVWSGPVTLDELARPGFALHTGAD
QVEVQLAVHGDHQVDNALCAAAVAVECGATLQQVATALSDAGPVSRHRMQVGTRADGVTV
INDAYNANPDSMRAGLKALAWMARQNPADPAGDLRGKRRSWAVLGEMAELGDDAITEHDA
IGRLAVRLDVSRLIVVGTGRTMNAMHHGAVMEGSWGSESTMVDDADAALALLQAELEPGD
VVLVKASNSVGLGALADALVAADTGSPSPTEMGNADR
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgagatgaccgtcgccaggatcgccgagatcgtcggcggtgagctggccgacatc
accgccgagcaggcggccgccactcgggtcaccggcaccgtcgaattcgactcgcgggcg
atcgggccgggtgggttgttcctggcgctgccgggtgcccgcgccgacggtcatgacttc
gcggcggccgcggtggcgtccggggcgcccgtggtgctggccgcacgtccggtgggggta
cccgcgatcgtggtgcgtccggagccgggcgccgccgatgccgcttccggcgctttggaa
ttcgacaccgacggctccggtgcggcggtgctggccgcgctggccaagctcgctgcggcg
gtcgccgccgagctggtggccgacgggctcacgatcatcggggtgaccggatcttcgggc
aagacctcgaccaaggatctgctggccgcggtgctggccccgctcggtcaggtgatcgcg
ccgccgggctcgttcaacaacgagctcggtcacccgtggacggtgctgcgcgccacgccg
gagaccgattacctgatcctggagatgtcggcccggcatccgggcaatatcgcggccctg
gccgccatcgctccgccgcagatcgcggtggtgctcaacgtgggcaccgcccacctcggt
gagttcggctcgcgtgaggccatcgcgaataccaaagccgagttgccgcaagctgttccg
gcctcgggcgtggtgatcctcaacgtcgacgacacggcggtggcggcgatggccgatgcg
accgcggcccgtgtggtgcgggtctcgcgtgagcccggcgcgcaggtcgacgtgtggtcc
ggcccggtcaccctcgacgagttggcccggccggggttcgcgctgcacaccggcgccgac
caggtcgaggtgcaactcgcggtgcacggcgatcaccaggtcgacaatgcgctgtgtgcg
gccgcggtggcggtggagtgcggggcgaccctgcagcaggtggccacggcgctgtccgat
gcgggccccgtgtcgcggcaccggatgcaggtgggcacccgcgccgacggtgtgacggtg
atcaacgacgcctacaacgccaacccggattcgatgcgggccggtctcaaggcgctggcc
tggatggcgcgccagaaccccgctgatcccgccggtgacctgcgcggaaaacggcgcagc
tgggcggtgttgggcgagatggccgaactcggtgacgacgcgataaccgagcacgacgcg
atcggacggctggcggtgcgcttagatgtgtctcggttaatcgtcgtcggaaccgggagg
actatgaacgccatgcaccacggcgcggtgatggagggttcgtggggatctgagtccacg
atggtcgacgacgccgatgccgccctggccctgctgcaggctgagctggagcctggggac
gtggtgctggtgaaggcatccaactccgtgggtctgggcgcgctggccgatgcgctggtt
gccgctgataccggatcgccgtctccgacggaaatggggaacgccgaccgatga
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