Mycobacterium intracellulare subsp. yongonense: OEM_03570
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Entry
OEM_03570 CDS
T02732
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
myo
Mycobacterium intracellulare subsp. yongonense
Pathway
myo00290
Valine, leucine and isoleucine biosynthesis
myo00620
Pyruvate metabolism
myo01100
Metabolic pathways
myo01110
Biosynthesis of secondary metabolites
myo01210
2-Oxocarboxylic acid metabolism
myo01230
Biosynthesis of amino acids
Module
myo_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
myo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
OEM_03570
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
OEM_03570
Enzymes [BR:
myo01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
OEM_03570
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AGP61893
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Position
complement(358948..360747)
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AA seq
599 aa
AA seq
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MTSNSDAFSSTRSIVKPAGPRGPGQPAWNPQRGSSMPVSRYRPFAEEVEPIRLADRTWPD
QVITSAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFV
REIITGGAIPDDVTIQVLTQCRPELIERTFEACQGAPQAIVHFYNSTSILQRRVVFRAEK
AAVQDIATAGARKCVEEAAKYPGTRWRFEYSPESYTGTELEYAKQVCDAVGEIISPTPEN
PIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYQAGA
DRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHP
YGGDLVYTAFSGSHQDAINKGLDQMKVDADAADTDVEDMLWQVPYLPIDPKDVGRTYEAV
IRVNSQSGKGGVAYIMKSDHGLALPRRLQIEFSQVVQKISEGEGGEVSPKEMWDAFSEEY
LAPVWPLERVKQRVDASEEDSGVTSIAATVKINGVETEISGSGNGPLAAFVHALGDVGFD
VAVLDYSEHAMSSGDDAQAAAYVEASVNGRTVWGVGIAPSITTASLRAVVSAVNRAARA
NT seq
1800 nt
NT seq
+upstream
nt +downstream
nt
gtgacttccaattccgacgcattcagctcgacacgcagcatcgtcaaacccgcgggcccg
cgggggcccgggcagcccgcatggaacccccagcgcggctcgtcgatgccggtcagccgg
taccggcccttcgccgaagaggtcgagccgatccggctcgccgatcgcacctggcccgac
caggtcatcaccagcgcgccgctgtggtgcgcggtggacctgcgcgacggcaaccaggcg
ctgatcgacccgatgagcccggcccgcaagcgccgcatgttcgatctgctggtccgcatg
ggctacaaggagatcgaggtcgggttcccgtcggccagtcaaaccgacttcgacttcgtc
cgcgagatcatcaccggcggcgccatccccgacgacgtcaccatccaggtgctgacccag
tgccggccggaactgatcgagcgcacgttcgaggcgtgccagggcgcgccgcaggccatc
gtgcacttctacaactcgacgtcaatcctgcagcgccgcgtcgtatttcgcgccgaaaag
gccgcggtgcaagacatcgcgaccgcgggcgcccgcaagtgcgtcgaggaggccgccaag
tacccgggcacgcggtggcggttcgagtattcgccggagtcctacaccggaaccgagctg
gagtacgccaagcaggtgtgcgacgccgtcggcgaaatcatcagtcccacaccggaaaac
ccgatcatcttcaacctgcccgccaccgtggagatggccacccccaacgtctacgccgat
tcgatcgagtggatgagccgcaacctggccaaccgggaatcggtcatcctgagcctgcat
ccgcacaacgaccgcggaaccgccgttgccgcagcggaattgggctaccaggcgggcgcc
gaccggatcgagggctgcctgttcggcaacggcgagcgcaccggcaacgtctgcctggtg
acgctggggctgaacctgttctcgcgcggcgtggacccgcagatcgacttctccaacatc
gacgagatccgccgcacggtggagtactgcaaccagctgccggtccacgagcgtcacccc
tacggcggtgacctggtctacaccgcgttctccggcagccaccaggacgccatcaacaag
ggcctggaccagatgaaggtcgacgcggatgccgcggacaccgacgtcgaggacatgctc
tggcaggtgccgtatctgccgatcgaccccaaggatgtcgggcgcacctacgaggcggtg
atccgggtcaactcgcagtccggcaagggcggggtcgcctacatcatgaagtccgatcac
ggcctggccctgccgcggcggctgcagatcgagttctcccaggtggtgcagaagatcagc
gaaggggaaggcggcgaggtctcgccgaaggagatgtgggacgcgttctccgaggagtat
ctggccccggtgtggccgctggagcgggtgaagcagcgcgtcgacgcgtcggaggaggac
agcggcgtcaccagcatcgccgcgaccgtcaagatcaacggggtggagaccgagatcagt
gggtccggcaacggcccgctggccgcgttcgtccacgcgctgggcgatgtcggattcgac
gtggccgtgctggattactccgagcacgcgatgagttccggtgacgacgcgcaggccgcg
gcctacgtcgaggcatcggtcaacggccgcacggtgtggggtgtcggcatcgcgccgtcg
atcaccacggcgtcgctgcgtgcggtcgtgtcggcggtcaaccgcgcggcacgcgcctga
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