Myotis yumanensis (Yuma myotis): 139007222
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Entry
139007222 CDS
T10762
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
myum Myotis yumanensis (Yuma myotis)
Pathway
myum05012
Parkinson disease
myum05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
myum00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
139007222 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
139007222 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
myum01001
]
139007222 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
myum04131
]
139007222 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
myum04147
]
139007222 (LRRK2)
Enzymes [BR:
myum01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
139007222 (LRRK2)
Protein kinases [BR:
myum01001
]
Serine/threonine kinases: TKL group
LRRK family
139007222 (LRRK2)
Membrane trafficking [BR:
myum04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
139007222 (LRRK2)
Exosome [BR:
myum04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
139007222 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
Roc
LRR_8
COR
LRR_4
Ras
LRR_14
LRR_9
Beta-prop_RSE1_2nd
Beta-prop_EML_2
WDR55
LRR_NXF1-5
Arf
LRR_13
Ank_2
WD40_CDC20-Fz
ABC_tran
T2SSE
AAA_22
AAA_16
WD40_like
nSTAND3
Kdo
AAA_7
Beta-prop_RIG_2nd
G-alpha
PduV-EutP
TniB
Arm
WD40_Prp19
MMR_HSR1
ANAPC4_WD40
cobW
Septin
AAA_29
NACHT
FtsK_SpoIIIE
TrwB_AAD_bind
GTP_EFTU
MobB
SRPRB
TsaE
WD40_WDHD1_1st
ARM_LIN_2nd
AAA_23
ARM_CUL7_CUL9
Motif
Other DBs
NCBI-GeneID:
139007222
NCBI-ProteinID:
XP_070266525
LinkDB
All DBs
Position
Unknown
AA seq
2528 aa
AA seq
DB search
MASGSCQGCEEEDEETLKKLIVRLNNLQEGKQIETLVQILEDMQVFTYADHAAKLFQGKN
VHVPLLIVLDSYVRVACVQQVGWSLLCKLIEICPDIMQSLTGPQDIGCDWEVLGIHQLII
KMLTVHNASINLSMVGLKALDLLLTSGKITLLILDEESDIFLLIFDAMKKFSANDEVQKL
GCKALHVLFERVSEEQLTEFVENKDYMILLTALKNFKDEEEIVLYVLRCLHSLASPCNNV
EVLMSGNVRCYNIVVEAMKAFPVNEKIQEVSCCLLHRLTLGNFFNILVLNEVHVFVVEAV
QRYSENATLQIAGLSCLALLTETIFLNQDLEEKNENEENEDDEEEEKLFWLEACYKALTW
HRKNKHVQEAACWALNNLLMYQNSLHEKIGDEDGQFPAHREVMLSMLMHSSSKEVFQASA
NALCTLLEQNVNFRKILLSKGIYLNVLEFMKRHVHSPEVAESGCKMLNHLFEGSNISLDV
MAAVAPKIITVMKSHGTSLSVQLEALRAILHFMLPGMPEEFTEDTEYQHKLKMVTNQCFR
NDIHKLVLGSLNRFIGNPGIQKCGLKVISSIARFPDALEMLSLEGAIESVLQTLQMYPDD
QEIQRLGLSLIGCLITKKNLILGTENLLAKILVSSLQRFKDITELQTKGFQTVLTMLERS
ESFSKLLVHYSFDSVIFHQMSSSLMEKKDQQFLNLCCKCFAKLAMDDELKGVMLERACDQ
NNSVMVECLLLLGADANRAKEGTSLICQVCEKASSPKLVELLLNSGSREQDVRKALAISI
RKGDSQIISLLLKRLALDLANNSICLGGFCIGKIEPSWLGPLFPDKTCNSRKEINIGSTL
ARMVLRYQMKSCVAEGAASGSDGDFSEQVLGKFDQWTFIPESYVDSVFGQSDDLDSEGSE
GSFLVKKKSSSISVGEFYRDPALQRCSSHLQSHSNSLGPIFDQEDLLKRKRKILSSDDSL
RSSKLPSHMRNSDSTSSLASEREYITSLDLSANELRDIDALSQKCCISGHLEHLARLELH
QNALTGFPQRLCEVLRCLTHLDLHSNKFTAFPSYLLKMNCLANLDVSRNDIGPSVVLDPA
VKCPTLKQFNLSYNQLSSVPENLGDVAEKLEQLTLEGNKISGMCSPLSLKELKILNLSKN
HISSLSEDFLEACPKVENFSARMNSLAAMPFLPSSLTNIKLSQNRFTCVPEAILNLPHLR
SLDMSSNEIKYLPSPAHWKSLNLRELLFSHNQISILDLSEKAHAWSRVEKLHLSHNKLKE
IPPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELRLNFDFKHIGCKAKDII
RFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKEPDVGMQSATVGIDVRDWPIQ
IRGKRKKNLILNVWDFAGREEFYSTHPHFMTPRSLYLAVYDLSKGQAEVDAMKPWLFNIK
ARASSSPVILVGTHLDVSDEKQRKACISKINKELLNKRGFPAIRDYHFVNATVESDALAK
LRKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKRLLQLVKE
NQLQLEENELPHAVHFLNESGVLLHFQDPALQLSNLYFVEPKWLCKVMAQILTEKVEGFP
KYPKGIISRRSVEKFLSKEKRFPKNYTQQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPV
IELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGREQALRPNRMYWRQGIY
LNWSPEAYCLVESEVLDNHPESFLKITVPSCRKGCIILGQVVDHIDSLMEEWFPGLLETD
ICGEGETLLKKWALYSFNDGEEHEKILLDELMKKAEEGDLLINPDQPRLTLPISQIAPDL
ILADLPRNIMLNSEKLEFEQAPEFLLGDGSFGSVYRATYEGDEVAVKIFNKHTSLRLLRQ
ELVVLCHHHHPSLIFLLAAGIRPRMLVMELAPKGSLDRLLQQDTASLTRTLQHRIALHVA
DGLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFR
APEVARGNVIYNQQADVYSFGLLLYDILTTGDRIAEGLKFPNEFDELAIQGKLPDPVKEY
GCAPWPMVEKLIKRCLKENPQERPTSAQVFDILNSAELICLMRHISIPKNFTVECMVAAN
QSCKNASIWLGCGPRDRGQLSLLDLTTERLTSEEVTNSRILCLALVHLPVEKESWIVCGT
QSGELLVINSEDGKKMHTLEKMTDSVTCLHCNSISKQSKQKNFLLVGTADGNLAIFEDKS
VKCKGAAPLKILNIGNISTPLMCLSESVNSTEKNIMWGGCGTKLFSFSDDFTIQKLIETR
KTQLFPYAAVSDSNIIAVVVDRALYIAKKNSPLVEVWDKKTEKPCEVIDCAHFLKEEMVK
VNKESRHSMSYSGRVKTLCLQKNTALWIGTGGGYMLLLDLSTLRLIRIIHDFCDSVRVMM
TAQIGNLKNAMVVLGYTWKSTEDMQHQKELQSCLSIWDINLPHEVQNLEKHIEVRKELAE
RMRRITVE
NT seq
7587 nt
NT seq
+upstream
nt +downstream
nt
atggccagtggcagctgtcaggggtgcgaggaggaggacgaggaaactttgaagaagttg
atagtcaggctgaacaatctccaggaaggaaagcagatagagacgctggtccaaattctg
gaggatatgcaggtgttcacctacgctgaccacgccgccaagttatttcaaggcaaaaat
gtccacgtgcctctgttgatcgtcttggactcctatgtgagagtggcctgcgtgcagcag
gtgggttggtcacttctatgcaaattaatagaaatctgtccagatataatgcaaagctta
acgggaccccaggacattggatgtgattgggaagtccttggtattcaccaactgattatt
aaaatgcttacagttcataatgccagtataaacctgtcaatggttggactgaaggcctta
gatctccttctaacttcaggtaaaatcactttgctgatattggatgaagaaagcgatatt
ttcttattaatttttgatgccatgaaaaagttttcagcgaatgacgaggtccagaaactt
ggatgcaaagctttacatgtgctgtttgagagagtttcagaggagcaactgactgaattt
gtcgagaataaagattatatgatattgctaactgcattaaaaaactttaaagatgaggag
gaaattgtgctttacgtactgcgctgtttacattccctagcaagtccttgcaacaatgtt
gaagtcctcatgagtggcaacgtcaggtgttacaacattgtggtagaagccatgaaagca
ttccctgtcaatgaaaaaattcaagaagtgagttgctgcttgctccatagacttacatta
ggtaatttttttaatatcctggtattaaacgaggtgcacgtgtttgtggtggaagctgtg
cagcggtattcagagaatgcaacgctgcaaatcgcagggctcagctgtttagcgctcctc
acggagaccatttttttaaatcaagatttagaggaaaagaatgaaaatgaggagaatgaa
gatgatgaggaagaagagaaattgttttggctagaagcctgttacaaagccctcacttgg
catagaaagaacaagcatgtgcaggaggctgcctgctgggccctaaacaatctccttatg
taccagaacagtttgcacgagaagattggagatgaagatggccaattcccagctcatcgg
gaagtgatgctctccatgctgatgcattcttcgtcaaaagaagtctttcaggcatctgcg
aacgctttgtgcactctcctagaacaaaatgttaatttcagaaaaatcctgttgtcaaaa
ggaatctacctaaacgtgctggagtttatgaagaggcatgtacactcccctgaagtggct
gaaagtggctgcaaaatgctgaatcatctttttgaaggaagtaacatttccctggatgta
atggcggcagtggcccccaaaataataacagttatgaaaagtcacgggacatcattgtca
gtgcagctggaggcacttcgagccattttacattttatgcttccaggcatgccagaggaa
ttcacagaagataccgaatatcaacacaagctaaaaatggttacaaatcagtgtttcagg
aatgatattcacaaactggtcctgggatctttaaacaggttcattggaaatcctgggatt
cagaaatgtggattaaaagtaatttcttctatagcacgttttcctgatgccttagagatg
ttatctctggaaggtgctattgaatcggtgcttcaaacactgcagatgtatccggatgac
caagaaattcagcgtctgggtttaagtcttataggatgcttgattacaaagaagaattta
atcctaggaactgagaatctgctggcaaaaattctggtttccagtttgcaacgatttaag
gatattactgaattacagactaaaggatttcagacagtcttgaccatgctggaacggtca
gagtctttttccaagctgttggtgcattattcctttgactcagtaatattccatcagatg
tcctccagtctcatggaaaagaaggatcaacagtttctaaacctttgttgcaagtgcttt
gcaaaattagccatggatgatgagttaaaaggtgtgatgctagagagagcatgcgatcag
aataacagcgtcatggttgaatgcttgcttctattgggagcggacgccaatcgagcaaag
gagggaacttctttaatttgtcaggtgtgtgaaaaagcaagcagtcctaaactggtggaa
ctgttattgaatagtgggtcccgtgaacaagacgtacgaaaagcgctggcaataagcatc
aggaaaggcgacagccagatcatcagtttgctcttaaagagacttgccctggacctggcc
aataacagcatatgcctcggaggattttgcatcgggaaaatcgaaccttcttggcttggt
cctttatttccagataagacatgcaattcaagaaaagaaataaatataggatccacacta
gcaagaatggtcctcagataccagatgaaaagttgtgtggcagagggagcagcctcaggc
agcgatggggatttttctgagcaagtacttggtaaatttgaccaatggaccttcattcct
gagtcctacgtggacagtgtgtttggacaaagtgatgacctagatagcgaaggaagtgaa
ggttcatttcttgtgaaaaagaagtcaagttcgattagtgtaggagaattttaccgagat
cctgccttgcaacgttgttcatcacatttgcaaagtcattccaattcattgggacccatt
tttgatcaagaagacttactgaagcgaaaaagaaaaatattgtcttcagatgattcactc
aggtcatcaaaacttccatcccatatgaggaattcagacagcacttcttccctggcttct
gagagagaatatattacatccctagatctttcagccaacgaactcagagatatcgatgcc
ctaagccagaagtgctgcatcagtggtcatctggagcacctggccaggctggagcttcac
cagaacgcactcacgggcttcccacagcggctatgcgaagtgctgaggtgtttgacgcac
ttggacttgcacagtaacaagttcacagcgtttccctcctacttgttgaaaatgaattgt
cttgccaaccttgatgtctctcgaaatgacatcgggccctcggtagttttggatcctgcc
gtgaagtgtccgaccttgaaacagttcaacctgtcctataaccagctgtcttctgttccc
gagaacctgggtgatgtggcagagaaactggagcagctgacgttagaaggaaataaaata
tcaggaatgtgttctcccctgagcctgaaggaactgaagattttaaatcttagtaaaaac
cacatttcatccctgtcagaggactttcttgaggcttgtcctaaagtggagaatttcagc
gccagaatgaactcccttgctgctatgccttttttaccttcttctctgacaaacatcaaa
ttatctcaaaacagatttacatgtgtcccagaagcaattttaaatcttccacacttgcga
tcattagacatgagcagcaacgaaattaaatacctaccaagtcctgcacactggaaatct
ttgaacttaagggaactcttgtttagtcataatcagatcagcatcttggacttgagcgaa
aaagcacatgcatggtctagagtagagaaactacatctttctcataataaactgaaagag
attcctcctgagattggctgtcttgaaaacctgacatctcttgatgttagttacaacttg
gaactgagatcctttcccaatgaaatggggaaattgagcaaaatatgggatcttcctttg
gatgagctgcgtcttaattttgattttaagcatataggatgtaaagccaaagacatcata
aggtttcttcaacagcgcttaaaaaaggctgtgccctataaccgcatgaaacttatgatt
gtgggaaacactgggagtggtaaaaccaccttattgcagcaattaatgaaaaccaaggaa
ccagatgttgggatgcaaagtgccaccgttggcatagacgtgagagactggcctatccaa
ataagaggcaaaaggaagaaaaacttgattctaaatgtgtgggattttgcaggtcgggag
gaattctacagcacgcacccgcacttcatgaccccgcgatcactgtacctcgccgtctat
gacctcagcaaagggcaggcggaagttgatgctatgaagccttggctattcaatataaag
gctcgagcttcctcttcccctgtgattcttgtgggcacacatttggatgtttctgatgag
aagcagcgcaaagcctgcatcagtaaaatcaacaaggagctcttgaacaagcgggggttt
cccgcaatccgggattaccactttgtgaacgccaccgtggaatccgatgctttggcaaaa
cttcggaaaaccatcataaatgagagcctcaatttcaagatccgagatcagcctgttgtt
gggcagctgattccagactgctatgtagaacttgagaaaatcattttatcagagcgtaaa
aatgtgccaattgaatttcctgtaattgaccggaaacgattattacaactcgtgaaagaa
aatcaactgcagttagaggaaaatgagcttcctcatgcagtgcacttcctaaatgaatca
ggggtccttcttcattttcaagacccagcactgcagttaagtaacttatattttgtggaa
cccaagtggctttgtaaagtcatggcacagattttgacagagaaagtagaaggctttcca
aaatatcctaaaggaattatttcacgtagaagtgtggaaaaatttctttcaaaggaaaag
agatttccaaagaactacacacaacagtacttcaaactcctagaaaaatttcagattgcc
ttgccaataggagaagaatatttgctggttccaagcagtctgtctgaccacaggcctgtg
atagagctcccccattgtgagaactctgaaattatcattcgactatatgaaatgccttat
tttccaatgggattttggtcgagattaatcaatcgattacttgaaatttcaccttacatg
ctttcaggtagagaacaagcacttcgcccaaacagaatgtattggcgacaaggcatctat
ttgaattggtctcctgaagcttattgcctggtagaatctgaagtcttagataatcatcca
gagagtttcctaaaaattacagttccttcttgtagaaaaggctgtattattttgggacaa
gttgtggaccacattgattctctcatggaagaatggtttcctgggttattggagactgat
atttgtggtgaaggagaaactttgttgaagaaatgggcattatatagttttaatgatggc
gaagaacatgaaaaaatcttacttgatgagttgatgaagaaagcagaagaaggagacctc
ctaataaatccagatcaaccaaggctcacccttccaatatcccagattgctcctgacttg
attttggctgacctgcctagaaatattatgttgaacagtgagaaattggaatttgaacaa
gctccagaatttctcttaggtgatggcagttttggatcagtttatcgagcaacctacgaa
ggagatgaagtggctgtaaagatatttaataaacatacatcacttagactgttaagacag
gagctggtggtgctttgccaccaccaccaccccagcttgatctttttgctggcggctggg
attcgtccccggatgctggtgatggagctggcccccaagggctccctggaccgcctgctg
cagcaggacacagccagtctcactcggactctgcaacataggatcgcgctccatgtggct
gacggcttgagatacctccactcggccatgattatataccgggatttgaagccccacaat
gtgctgctcttcaccctgtatcccaatgccgccatcatcgcaaagattgctgactacggg
attgctcagtactgctgcagaatggggattaaaacatcggagggcacaccaggctttcgt
gcacctgaagttgctagaggaaatgtaatttataaccaacaggctgatgtttattcattt
ggtttactactgtatgacattttgacaactggagatagaatagcagagggtttgaagttt
ccaaatgagtttgatgaattggcaatacaaggcaaattaccagatccagttaaagaatat
ggttgtgccccctggcctatggttgagaagttaattaagaggtgtttaaaagaaaatcct
caagaaaggcctacatctgcccaggtctttgacattttgaactcggcagagttaatctgt
ctgatgagacacatatccatacccaaaaacttcactgtggagtgcatggttgctgccaat
cagagctgcaagaatgccagcatctggctgggctgcgggcccagggacagaggccaactc
tcccttcttgacttaactactgaaagacttacttcggaggaagttaccaatagcagaata
ctgtgcctcgccttggtgcacctgcctgtggaaaaggaaagctggattgtgtgtgggaca
cagtctggcgagctcctcgtcattaattctgaagatgggaaaaagatgcatacccttgaa
aagatgaccgattctgttacttgcttgcattgcaattccatttccaaacaaagcaagcaa
aaaaattttcttttggtgggaactgctgatggcaacttagcaatttttgaagataaaagt
gttaagtgtaaaggagctgctcctctgaagatactcaatataggaaatatcagcactcca
ctcatgtgtttgagtgaatccgtgaattcaactgaaaaaaacattatgtggggaggatgt
ggcacaaaacttttctcgttttctgatgatttcaccattcagaaactcattgagaccagg
aaaactcagctgtttccttatgcagctgtcagtgactctaacatcatagcagtggtggtg
gacagagctctctacattgctaagaaaaatagcccacttgtggaagtgtgggataagaaa
acggaaaaaccctgtgaagtaatagactgtgcacactttttaaaggaggaaatggtgaaa
gtgaacaaggagtccagacacagtatgtcttactcggggagagtgaaaactctctgccta
cagaagaacactgctctctggattggaaccgggggaggctacatgctactccttgacctt
tcaactctcaggctcatccgtataattcacgacttctgtgactctgttcgagtcatgatg
acagcgcagataggaaatcttaaaaatgccatggtggttttgggatatacctggaaaagt
actgaagatatgcaacaccaaaaagaattacaatcttgcttgtctatttgggacatcaat
cttccacatgaagtgcaaaatttagaaaaacatattgaagtgagaaaagaattagctgaa
agaatgagaagaataactgttgaataa
DBGET
integrated database retrieval system
