Myotis yumanensis (Yuma myotis): 139016076 Help Entry 139016076         CDS       T10762                                  Symbol NOS3 Name (RefSeq) nitric oxide synthase 3   KO K13242   nitric-oxide synthase, endothelial [EC:1.14.13.39] Organism myum  Myotis yumanensis (Yuma myotis) Pathway myum00220   Arginine biosynthesis myum00330   Arginine and proline metabolism myum01100   Metabolic pathways myum04020   Calcium signaling pathway myum04022   cGMP-PKG signaling pathway myum04066   HIF-1 signaling pathway myum04071   Sphingolipid signaling pathway myum04151   PI3K-Akt signaling pathway myum04370   VEGF signaling pathway myum04371   Apelin signaling pathway myum04611   Platelet activation myum04915   Estrogen signaling pathway myum04921   Oxytocin signaling pathway myum04926   Relaxin signaling pathway myum04931   Insulin resistance myum04933   AGE-RAGE signaling pathway in diabetic complications myum05415   Diabetic cardiomyopathy myum05417   Lipid and atherosclerosis myum05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:myum00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     139016076 (NOS3)    00330 Arginine and proline metabolism     139016076 (NOS3)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     139016076 (NOS3)    04371 Apelin signaling pathway     139016076 (NOS3)    04066 HIF-1 signaling pathway     139016076 (NOS3)    04020 Calcium signaling pathway     139016076 (NOS3)    04071 Sphingolipid signaling pathway     139016076 (NOS3)    04022 cGMP-PKG signaling pathway     139016076 (NOS3)    04151 PI3K-Akt signaling pathway     139016076 (NOS3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     139016076 (NOS3)   09152 Endocrine system    04915 Estrogen signaling pathway     139016076 (NOS3)    04921 Oxytocin signaling pathway     139016076 (NOS3)    04926 Relaxin signaling pathway     139016076 (NOS3)  09160 Human Diseases   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     139016076 (NOS3)    05418 Fluid shear stress and atherosclerosis     139016076 (NOS3)    05415 Diabetic cardiomyopathy     139016076 (NOS3)   09167 Endocrine and metabolic disease    04931 Insulin resistance     139016076 (NOS3)    04933 AGE-RAGE signaling pathway in diabetic complications     139016076 (NOS3) Enzymes [BR:myum01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      139016076 (NOS3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 Motif Other DBs NCBI-GeneID:  139016076 NCBI-ProteinID:  XP_070279766 LinkDB All DBs Position Unknown AA seq 1203 aa AA seqDB search MGNLKSVGQEPGPPCGLGLGLGLSLCGKQGPASPAASEPSWTPATAPAPLPAPDPSPPLT RPPEGPRFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQSRPSQGSPPA EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN APRCVGRIQWGKLQVFDARDCSSAQEMFTYICSHIKYATNRGNLRSAITVFPQRAPGRGD FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPP ELFTVPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST EIGMRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDH HAATSSFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW KGSGAKGAGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSS PRPEQHKSYKMRFNSVSCTDPLVTSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHF CAFARAVDTRLEELGGERLLPLGQGDELCGQEEAFRGWAKGAFQASCETFCVGEDAKAAA RDIFSPKRSWKRQRYRLSTQAEGLQLLPGLIHVHRRKMFQATVLSVENLQSSKSTRATIL VRLDTGGQEGFQYQPGDHIGVCPPNRPGLVEALLSHVEDPPPPGEPVAVEQLEKGSPGGP PPGWVRDPRLPPCTLRQALTFFLDITSPPSPRLLRLLSTLAEEPGEQQELETLSQDPRRY EEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSVHPREIHLTVAVL AYRTQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAP FRGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYRDEVQGAQQRGVFGRVLTAFSRE PNSPKTYVQDILRTELAAEVHRVLCHERGHMFVCGDVTMATSVLQTVQRILATEGNMELD EAGDFIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRSAVPWAFDPPGPDT PCH NT seq 3612 nt NT seq  +upstreamnt  +downstreamnt atgggcaacttgaagagcgtgggccaggagcctgggccaccctgcggcctggggctgggg ctgggcctcagcctgtgcggcaagcaaggcccagcctcccctgcggcatccgagcccagc tggacaccagcaaccgcacccgcacccctgcctgcgccagaccccagccccccgctgacc cggcccccggaggggcccaggttccctcgtgtgaagaactgggaggtggggagcatcacc tatgacaccctgagtgcccaggcacagcaggacgggccctgcaccccacgacgctgcctg ggctccctggtatttccacggaaactgcagagccggccctcccagggctctccacccgcc gagcagctgctgagccaggccagggacttcatcaaccagtactacagctccatcaagagg agcggctcccaggcccatgagcagcgtcttcaggaggtggaagccgaggtggcggccaca ggcacctaccagctgcgggagagtgagctggtgttcggggccaagcaggcctggcgcaac gccccgcgctgcgtgggccggatccagtgggggaagctgcaggtgtttgatgcccgggat tgcagctccgcgcaggagatgttcacctacatctgcagccacatcaagtacgccaccaac cggggcaacctccgctcggccatcacagtgttcccccagcgcgccccgggccggggagac ttccgaatctggaacagccaactggtgcgctatgcaggctacaggcagcaggacggctct gtgcgaggggacccagccaacgtggagatcaccgagctctgcatccagcacggctggacc ccaggcaacggtcgcttcgacgtgctgcccctgctgctccaggccccagatgagcccccg gaactcttcactgtgccccccgagctagtcctcgaggtgccactggagcaccccacgctg gagtggtttgcagccctgggcctgcgctggtacgccctgccggctgtgtccaacatgctg ctggaaatcgggggcctggagtttcctgcggccccattcagtggctggtacatgagcaca gagatcggcatgcggaacctgtgtgaccctcaccgctacaacatcctggaggatgtggct gtctgcatggacctggacacccggacaacctcgtccctgtggaaagacaaggcagcagtg gagatcaacttggctgtgctgcacagttaccagctggccaaggtgaccatcgtggaccac cacgccgccacctcctccttcatgaagcacctggagaatgagcagaaggccagggggggc tgccctgccgactgggcctggatcgtgccccccatctcgggcagcctcacccctgtcttc catcaggagatggtcaactatttcctgtcccctgccttccgctaccagccagatccctgg aagggaagtggagccaagggtgccggcatcaccaggaagaagacctttaaggaagtggcc aatgcggtgaagatctctgcctcactcatgggcacggtgatggccaagcgtgtgaaggcc acaatcctgtacggctccgagaccggccgggcccagagctacgcgcagcagctggggagg ctcttccggaaggctttcgacccccgggtcctgtgcatggatgagtatgacgtggtgtcc cttgagcacgagacgctggtgttggtggtgaccagcacatttgggaatggggatccccca gagaatggagagagtttcgcggcggccctgatggagatgtcgggcccctacaacagctcc cctcggcccgaacagcacaagagttacaaaatgcgcttcaacagcgtctcctgcacagac ccgctggtgacctcctggcggcggaagaggaaggagtccagcaacacagacagcgcaggg gcgctggggaccctcaggttctgtgtgttcggcctgggctcccgggcgtacccccacttc tgcgcctttgctcgcgcggtggacacacggctggaagagctgggtggggagcggctcctg cctctgggccagggcgacgagttgtgcggccaggaggaggccttccgcggctgggccaag ggcgccttccaggcctcctgcgagaccttctgcgtgggagaagatgccaaggccgctgcc cgggacatattcagccccaaacggagctggaagcgccagaggtaccggctaagtacccag gccgagggcctccaactgctgccaggcctgatccacgtgcacaggaggaagatgttccag gccacagtcctctcagtggaaaacctgcaaagcagcaagtccacccgggccacgatcctg gtgcgcctggacactggaggccaggaggggttccagtaccagccgggggaccacatcggc gtctgcccgcccaaccggcccggccttgtggaggccctgctgagccacgtggaggaccca ccccccccaggcgagccagtggccgtggagcagctggagaagggcagccctggtggccct ccccccggctgggtgcgggacccccggctgcccccgtgcacgctgcgccaggctctcacc ttcttcctggacatcacttccccgcccagccctcgcctccttcgactgctcagcaccctg gctgaagagcccggcgaacagcaggagctcgagaccctcagccaggacccccggcgctac gaggagtggaagtggttccgctgccccacgctactggaggtgctggagcagtttccgtcg gtggcactgcctgccccgctgctcctcacccagctacccctgctccagccccggtactat tccgtcagctcagcacccagtgtccacccacgggagatccacctcacagtggccgtgctg gcataccggacccaggatgggctgggtcccctgcactatggagtctgctccacatggctc agccagctcaaggccggagaccctgtgccctgcttcatcaggggggctccctccttccgg ctgccacccgaccccagcttgccctgcatcctggtgggcccaggcactggcatcgccccc ttccggggattctggcaggagcggctgcacgacattgagagcaaaggcctgcagcccgcc cccatgacgttggtgtttggctgccgatgctcccagcttgaccacctctaccgcgatgag gtgcagggtgcccagcagcgcggggtgttcggccgcgttctcaccgccttctcccgggaa cccaacagcccgaagacctacgtgcaggacatccttcggacagagctagccgcggaggtg caccgcgtgctgtgccacgaacggggccacatgtttgtctgcggcgacgtcaccatggca accagcgtcctgcaaacggtgcagcgcatcctggcgacagagggcaacatggagctggac gaggccggcgacttcatcggcgtgctgcgggatcagcaacgctatcacgaggacattttc gggctcacgctgcgcacccaggaggtgaccagccgcatacgcacccagagtttctccttg caggagcggcatctgcggagcgcagtgccctgggctttcgacccacccggccccgacacc ccttgccactga

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