Myotis yumanensis (Yuma myotis): 139021875
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Entry
139021875 CDS
T10762
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
myum Myotis yumanensis (Yuma myotis)
Pathway
myum00562
Inositol phosphate metabolism
myum01100
Metabolic pathways
myum04014
Ras signaling pathway
myum04015
Rap1 signaling pathway
myum04020
Calcium signaling pathway
myum04024
cAMP signaling pathway
myum04070
Phosphatidylinositol signaling system
myum04919
Thyroid hormone signaling pathway
myum04933
AGE-RAGE signaling pathway in diabetic complications
myum05205
Proteoglycans in cancer
Module
myum_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
myum00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
139021875 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
139021875 (PLCE1)
04015 Rap1 signaling pathway
139021875 (PLCE1)
04020 Calcium signaling pathway
139021875 (PLCE1)
04070 Phosphatidylinositol signaling system
139021875 (PLCE1)
04024 cAMP signaling pathway
139021875 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
139021875 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
139021875 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
139021875 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
myum04131
]
139021875 (PLCE1)
Enzymes [BR:
myum01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
139021875 (PLCE1)
Membrane trafficking [BR:
myum04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
139021875 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
139021875 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
139021875
NCBI-ProteinID:
XP_070288771
LinkDB
All DBs
Position
Unknown
AA seq
2309 aa
AA seq
DB search
MTSEEMAASDLIPVTQRKVVSSQSAADESSEKASGVSVPKTHTPGQSRPISHTISKLNKP
KEETSGSNLPRILSTTRGKIMSDENSNETCWEKNMPDSVKNLNVNGNNILENRQCGLPQS
QFYKTCDSVVEEGLHLETGIPSSLERKVFPGIQLELDGPPTGIRPLGNQSATSRAHPDSD
LAVFHFHYELDRRMSDSVCTLSDNLILDDCGNCVSLPDVGREQKKNYMAYTCKLMELAKS
CDNENKQRQGDHCDALNDEYMCCEASCRKANVVCSSDSFCREGFTDSPSAETFLSHFEDF
PDNCEDVEDYFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLAAWSYI
DMKRSGSSLPCGRVTGQLSTVLIRQDGSPCLSEAQWYPIYNAVRRGEETEDTIGSLLHFF
TKLPASETAYERINVGPCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGARSGL
LSTFGGSTGRMMLKERQPGTSVANSSALPSSSAGISKELIDLQPLIQFPEEVASILMEQE
QNIYRRVLPVDYLCFLTQNLSTPECQRSLPCLKASISASILNSQNREHNALEDLVMRFNE
VSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNTVMEFLAGLRSRKVLKMWQFM
DQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCRVVPFCGVFLKELCEVLDGASGL
VKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRSLEA
EDEDSPSEGSGSRKNSLKDKARCQFVIGDLLDTENDIFEQPKEWDPHGLEEPQKAFDHGI
ELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWTKPTTASPAS
AKAKLGMPTATSEPGKFPLLGNAGLSGLAEGVLDLFSVKAVYMGHPSIDIHTVCVQNKLS
SMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTKAVRKMRKFPDQRQQWL
RKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNMQRNNTLGIGT
AKKKKKILMRGESGEATDDEMATRKAKLHKECRSWSGSDPQDINEQEESEANAITSPPNP
LPSRRAHSLTTAGSPILAAGTSSPIRPVSSPVLSSNKSPSSAWSSSSWHGRIKGGMKGFQ
SFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDLYAVPCNRSGSESAPLYTNLTIDENT
SGLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGVFGV
GILQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKDNFASKN
DESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGD
DGMPIIYHGHTLTTKIPFKDVIEAIDRSAFINSDLPIIISIENHCSLPQQRKMADIFKTV
FGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQA
QAYNGGNVNPPPTNNEEEEDEEDEYDYDYESLSDADVLTASPAPNCQEDNILEDRPESKS
CSDKLQFEYNEEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVI
YCQAVKFPGLSTLNASGSNRGKERKSRKSIFGNNPGRMSPGETASLNKTSGKSSYEGMRQ
AWEESSSPLSPATSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPA
ATRIDSSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNC
PMYQKFSPLERDLDNMEPAVYSLTIVSGQNVCPSNSTGSPCIEVDILGMPLDSCHFRTKP
IHRNTLNPMWNEQFFFRVHFEDLIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRN
LHNEVLEISSLFVNSRRMEEISSGSSVPASLMFSTEERKCLQTHRVTVHGVPGPEPFTVF
SINGGTKAKQLLQQILTTEQDTRPIAADYFLMEEKYFISKEKNECRKQPFQRAIGPEEEI
VQILSSWFPEEGYVGRIVLKTQQENLEEKSIVQDDREVILSSEEESFFVQVHDVSPEQPR
TVIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPNDYVLLEEVVKDTANKKSSTPKSSQR
VLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLT
SPSQVLVSESVQNKEERPVGGSDTMDYRQ
NT seq
6930 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcagcttctgatctcatacctgtgactcagagaaaagtggtg
tcttctcagtcagctgcagatgaaagtagtgaaaaggcctcaggcgtcagtgttccaaag
acacatactcctgggcagagtaggccgatttctcataccatctcaaaactgaacaaaccc
aaagaggaaacttctggaagcaacttgcctaggattctctcaacaacaagggggaaaatc
atgagtgatgagaacagtaacgaaacatgctgggagaaaaacatgcccgattctgtgaag
aaccttaatgtgaacggcaacaacatattggaaaaccgtcagtgtggtcttcctcagagc
cagttttacaaaacatgcgattctgttgtagaggaaggcctgcatttggaaactggaatc
ccttcttccctggaaagaaaggtgttccctgggattcaactggaactagacggacctccc
acgggcattcgtcccttaggaaatcaatcagcaaccagcagggcacaccccgacagcgat
ttggcggtatttcactttcattatgagcttgaccgaagaatgtcggacagtgtctgtacc
ctatcagacaacttgattttggatgattgtggaaactgtgtatcactgcctgatgttggt
agggagcaaaagaaaaattatatggcatatacttgcaaactgatggaattggcaaaaagc
tgtgataatgagaacaagcagcgacagggtgatcattgtgacgccttgaacgatgaatat
atgtgctgcgaagcttcctgccgaaaggccaacgtggtatgttctagtgacagcttctgc
agggagggttttactgatagtccatctgccgagacttttctgagccattttgaggacttc
cctgataattgtgaagacgtagaagattattttaaaagtaaaaaggagcgatccactttg
ttagtgaggagattttgtaaaaatgacagagaagttaagaaatctgtgtatactgggaca
agggcaattgtgaggactctgccttctggtcacattggactggcagcttggagttacatt
gatatgaagagaagtggaagctcgttgccttgtgggagagtaacgggccagctatcaaca
gtgctaattaggcaagatgggagcccatgtctgtcagaagcccagtggtatccgatctac
aatgcagtgagaaggggagaagaaacagaagatacaattggatctcttctccatttcttc
acaaagctcccagcctctgagacagcctatgaaaggattaatgttggtccctgcttaaag
caatgtgtccgagacaccgtatgtgagtaccgcgccaccctccaacggacctccatatct
cagtacatcacgggttctctcctagaagcaaccacatctttaggagcaagaagtgggctt
ctcagtacttttggaggatccaccggacgaatgatgctgaaagaacgccaaccgggcacc
tctgtggccaattccagtgccctcccttcaagttcagctgggatcagcaaggagctgatt
gatctgcagcccctcatccagttccccgaggaagtcgccagcatcctgatggagcaggaa
cagaatatctaccgaagggtcttgccggttgactatctttgcttcttgacccagaacttg
agcactccagaatgtcagaggtccctgccctgcctcaaagcatccatctcagcatcaatt
cttaactcccagaacagagagcacaatgcccttgaagatcttgtgatgagatttaatgag
gtgagctcctgggtgacgtggctgatcctcacagccggctccatggaggagaagcgggaa
gtcttctcatatttggtgcatgtggccaaatgctgctggaacatgggcaactacaacact
gtcatggagttcttggccggcctcaggtcaagaaaagttttaaaaatgtggcagttcatg
gaccagtctgacctggagaccatgaggagtctgaaggatgccatggctcagcacgaatcc
tcctgcgagtacaggaaggtggtgacgcgggcgctgcacatcccgggctgcagggtggtc
ccgttctgcggggtgtttctgaaggagctctgcgaagtgctggacggcgcctccggcctc
gtgaagctctgccccagatacaattcccaggaggaaactctagagtttgtagctgactac
agtggacaagataattttttacaacgcgtgggacaaaatggcttaaagaattcggaaaaa
gagtccaccgtcaacagcatctttcagatcatcaggagctgcagccgcagtctggaggcg
gaggacgaggacagccccagtgaggggagcggctctcggaaaaactccctgaaggacaaa
gctcgctgccagtttgtaattggagatttactggatacagaaaatgacatctttgagcag
cccaaagaatgggaccctcatggattagaagagccacagaaggcctttgaccacgggata
gagctcatcccatggtacgtgctgtccatccgagctgatgtgcaccagttcctgctgcag
ggggccacggtcatccactatgaccaggacacgcacctctctgcccgctgcttcctccag
cttcagcctgacaatagcaccttgacctggacaaagcccaccacggcctccccagccagt
gcaaaagcaaaacttggtatgcctactgccacgtccgagcctggcaaattcccgttactg
ggcaatgctggattaagtggcctggcggagggggtcttggatttgttttccgtaaaggct
gtgtacatggggcaccctagcattgatatacacactgtgtgtgttcagaacaaactgagt
agcatgtttctctcggagactggtgtgacactgctctatgggcttcagaccacggacaat
agattactgcactttgtggcaccaaagcacacagctaaaatgctcttcagtggattgctg
gaactcactaaagctgtgagaaagatgaggaagttccctgaccaaagacagcagtggctg
cggaaacagtacgtcagcctctatcaggaggatggacggtatgaaggcccaactttggct
cacgctgtggagttgtttggtggcagacgatggagtactcgaaaccccagccctgggaca
tcagcaaagagtgccgagaagcccaacatgcagaggaacaacaccctgggcatcggtact
gccaagaagaagaagaaaatccttatgaggggtgagagtggagaggccaccgacgatgag
atggccacccgaaaggccaaactgcacaaagagtgtcgaagctggagtggctctgatcct
caggacattaacgagcaagaggagtcagaggcgaatgccatcacaagcccgcctaaccct
ctcccttccagaagagcccattctctgactacggctgggtcccccatcttggctgccggg
acgtcatctcccatcaggccagtgtcctcccctgtgctgtcttcaaacaagagcccgtcc
agtgcctggagcagcagcagctggcacggccgcatcaaaggaggaatgaaaggcttccag
agcttcatggtttccgacagcaacatgagttttgttgaatttgtggagctgttcaaatcc
ttcagtgtaaggagccgcaaggacctgaaggatctcttcgacctctacgccgtgccctgc
aaccggtcgggctctgagtcggccccgctctacaccaacctaaccattgacgagaacacc
agtggtcttcagcctgatctagatttgttgaccagaaatgtctcagatttggggctgttc
attaagagtaaacagcagctgtcagacaaccagaggcagatctctgacgccattgctgct
gcaagcatcgtgacgaatggcactggggtcgagagcacatccctgggcgtgtttggggtc
ggcatacttcagctcaatgacttcctagtgaactgccagggagaacactgcacttacgat
gaaatcctcagcatcatccagaagtttgagcctagcattagtatgtgtcatcagggccta
atgtcatttgaaggatttgcaaggtttctgatggataaagacaactttgcttcgaaaaac
gatgaatcacaggagaacattaaagaattacagctgcccctctcctactattacattgaa
tcttcacacaatacctacctcacaggccatcagctcaaaggagaatcctcagtagaactc
tacagccaggtcctcctgcaaggctgtaggagcgtagagttggactgctgggacggagat
gatgggatgcccattatttaccatggacatacactgacaaccaagatccccttcaaggac
gtgatcgaagccattgatcgcagtgccttcatcaactctgacctgccaatcatcatatca
attgaaaaccactgttcattgcctcagcaacgaaaaatggcagacattttcaagactgta
tttggagaaaaactggtggctaagttcttatttgaaagtgatttctcagatgatccaatg
cttccttctcctgaccaacttagaaggaaggtacttctcaaaaataagaagctaaaagcc
caccagacgccggtggatatcttaaagcaaaaggctcatcagttagcatccatgcaagct
caggcttacaatggtgggaatgtcaaccccccacctactaataatgaggaggaggaagat
gaagaggacgagtatgattatgactatgaatctctctctgatgcagatgtccttactgct
tctcctgctcctaactgtcaggaagataacattctagaagacagacctgaaagcaaatcg
tgtagcgacaagcttcagtttgagtataatgaagaaatccccaagaggataaagaaagca
gacaactctgcttgcaacaaaggaaaggtgtatgacatggagttgggagaagaattttat
cttcctcagaataaaaaagaaagcagacagattgcaccagagctttccgaccttgtcatc
tattgccaagcagtaaaattcccaggcctgtcaactctaaatgcatctggctctaacaga
ggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggcagaatgagccct
ggggagacggcatcacttaacaaaacatctggaaaaagttcctatgaaggaatgcgacag
gcctgggaggagtcttcttctcccctcagcccagccacgtccctcagcgctatcattaga
actcccaaatgttaccatatctcatcgctgaatgaaaatgccgccaaacgtctgtgtcgc
aggtattctcagaaactgatccagcacaccgcctgtcagctgctgaggacttacccggct
gccacccgcatcgactcctccaaccctaaccccctcatgttctggctgcacgggatacag
ctcgtggcactcaactaccagacagatgatctccctttacatttaaacgctgccatgttt
gaggccaacggtggctgtggctatgtgttgaaacccccagttctgtgggacaagaactgc
cccatgtatcagaagttttctcccctggaaagagacctggacaacatggagcccgccgtc
tactctttgactattgtctctggccagaacgtgtgcccgagcaacagcacaggaagcccg
tgcatcgaggtcgacatcctgggcatgccgctggacagctgccacttccgcacgaagccc
atccaccggaacactctgaaccccatgtggaacgagcagtttttcttccgggttcacttt
gaagacctcatatttcttcgttttgcagttgtggaaaacaacagctcggcggtcactgct
cagaggattatcccgctcaaggctctaaagcgaggatatcgacatcttcagctgcgaaac
ctccacaatgaagtcttggaaatctctagtttattcgtaaacagcagaaggatggaagaa
atctcctctggcagttccgtgccggcctctttgatgtttagtacagaagaaagaaagtgt
ctgcagactcacagagtcacggtgcatggcgtcccaggtccggagcccttcactgttttc
tctataaatggaggcaccaaggcaaagcaacttctccagcaaattctgaccactgaacaa
gacaccagacctattgccgcagactactttttgatggaagaaaaatattttatatctaaa
gaaaagaatgaatgcagaaaacagccgttccagagggccattggtcccgaggaagagatc
gtgcagattttaagcagctggtttccagaagagggctatgttggcaggattgtcttaaaa
acccagcaggaaaacctggaagagaaaagcattgttcaagatgacagagaggtgatcttg
agctcggaggaggagagtttctttgtccaagtgcacgacgtttctccagagcagccgcgg
acggtcatcaaagcgccgcgcgtcagcaccgcacaggacgtcattcagcagaccttatgc
aaagccaagtactcctacagcatcctgagcaaccccaacccgaacgactacgtacttttg
gaagaggtggtgaaagacacagccaacaagaagtcttctacccccaagtcctcccagcgg
gtccttttggatcaagagtgtgtgtttcaagcccaaagcaagtggaaaggtgcaggaaaa
ttcatccttaagctaaaggagcaagtgcaggcatccagagaagacaagagaaaaggcatt
tcttttgcaagtgaattcaagaagttcaccaagtcaactaaacagccccgaggactcaca
tcaccttctcaggtcttggtttcggaaagtgtccaaaacaaagaggagagacctgtgggt
ggcagcgacacgatggactatcgacagtga
DBGET
integrated database retrieval system