KEGG   Myotis yumanensis (Yuma myotis): 139021875
Entry
139021875         CDS       T10762                                 
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
myum  Myotis yumanensis (Yuma myotis)
Pathway
myum00562  Inositol phosphate metabolism
myum01100  Metabolic pathways
myum04014  Ras signaling pathway
myum04015  Rap1 signaling pathway
myum04020  Calcium signaling pathway
myum04024  cAMP signaling pathway
myum04070  Phosphatidylinositol signaling system
myum04919  Thyroid hormone signaling pathway
myum04933  AGE-RAGE signaling pathway in diabetic complications
myum05205  Proteoglycans in cancer
Module
myum_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:myum00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    139021875 (PLCE1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    139021875 (PLCE1)
   04015 Rap1 signaling pathway
    139021875 (PLCE1)
   04020 Calcium signaling pathway
    139021875 (PLCE1)
   04070 Phosphatidylinositol signaling system
    139021875 (PLCE1)
   04024 cAMP signaling pathway
    139021875 (PLCE1)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    139021875 (PLCE1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    139021875 (PLCE1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    139021875 (PLCE1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:myum04131]
    139021875 (PLCE1)
Enzymes [BR:myum01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     139021875 (PLCE1)
Membrane trafficking [BR:myum04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    139021875 (PLCE1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    139021875 (PLCE1)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RasGEF RA C2 EF-hand_like GDPD
Other DBs
NCBI-GeneID: 139021875
NCBI-ProteinID: XP_070288771
LinkDB
Position
Unknown
AA seq 2309 aa
MTSEEMAASDLIPVTQRKVVSSQSAADESSEKASGVSVPKTHTPGQSRPISHTISKLNKP
KEETSGSNLPRILSTTRGKIMSDENSNETCWEKNMPDSVKNLNVNGNNILENRQCGLPQS
QFYKTCDSVVEEGLHLETGIPSSLERKVFPGIQLELDGPPTGIRPLGNQSATSRAHPDSD
LAVFHFHYELDRRMSDSVCTLSDNLILDDCGNCVSLPDVGREQKKNYMAYTCKLMELAKS
CDNENKQRQGDHCDALNDEYMCCEASCRKANVVCSSDSFCREGFTDSPSAETFLSHFEDF
PDNCEDVEDYFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLAAWSYI
DMKRSGSSLPCGRVTGQLSTVLIRQDGSPCLSEAQWYPIYNAVRRGEETEDTIGSLLHFF
TKLPASETAYERINVGPCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGARSGL
LSTFGGSTGRMMLKERQPGTSVANSSALPSSSAGISKELIDLQPLIQFPEEVASILMEQE
QNIYRRVLPVDYLCFLTQNLSTPECQRSLPCLKASISASILNSQNREHNALEDLVMRFNE
VSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNTVMEFLAGLRSRKVLKMWQFM
DQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCRVVPFCGVFLKELCEVLDGASGL
VKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRSLEA
EDEDSPSEGSGSRKNSLKDKARCQFVIGDLLDTENDIFEQPKEWDPHGLEEPQKAFDHGI
ELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWTKPTTASPAS
AKAKLGMPTATSEPGKFPLLGNAGLSGLAEGVLDLFSVKAVYMGHPSIDIHTVCVQNKLS
SMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTKAVRKMRKFPDQRQQWL
RKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNMQRNNTLGIGT
AKKKKKILMRGESGEATDDEMATRKAKLHKECRSWSGSDPQDINEQEESEANAITSPPNP
LPSRRAHSLTTAGSPILAAGTSSPIRPVSSPVLSSNKSPSSAWSSSSWHGRIKGGMKGFQ
SFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDLYAVPCNRSGSESAPLYTNLTIDENT
SGLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGVFGV
GILQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKDNFASKN
DESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGD
DGMPIIYHGHTLTTKIPFKDVIEAIDRSAFINSDLPIIISIENHCSLPQQRKMADIFKTV
FGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQA
QAYNGGNVNPPPTNNEEEEDEEDEYDYDYESLSDADVLTASPAPNCQEDNILEDRPESKS
CSDKLQFEYNEEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVI
YCQAVKFPGLSTLNASGSNRGKERKSRKSIFGNNPGRMSPGETASLNKTSGKSSYEGMRQ
AWEESSSPLSPATSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPA
ATRIDSSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNC
PMYQKFSPLERDLDNMEPAVYSLTIVSGQNVCPSNSTGSPCIEVDILGMPLDSCHFRTKP
IHRNTLNPMWNEQFFFRVHFEDLIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRN
LHNEVLEISSLFVNSRRMEEISSGSSVPASLMFSTEERKCLQTHRVTVHGVPGPEPFTVF
SINGGTKAKQLLQQILTTEQDTRPIAADYFLMEEKYFISKEKNECRKQPFQRAIGPEEEI
VQILSSWFPEEGYVGRIVLKTQQENLEEKSIVQDDREVILSSEEESFFVQVHDVSPEQPR
TVIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPNDYVLLEEVVKDTANKKSSTPKSSQR
VLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLT
SPSQVLVSESVQNKEERPVGGSDTMDYRQ
NT seq 6930 nt   +upstreamnt  +downstreamnt
atgacttctgaagaaatggcagcttctgatctcatacctgtgactcagagaaaagtggtg
tcttctcagtcagctgcagatgaaagtagtgaaaaggcctcaggcgtcagtgttccaaag
acacatactcctgggcagagtaggccgatttctcataccatctcaaaactgaacaaaccc
aaagaggaaacttctggaagcaacttgcctaggattctctcaacaacaagggggaaaatc
atgagtgatgagaacagtaacgaaacatgctgggagaaaaacatgcccgattctgtgaag
aaccttaatgtgaacggcaacaacatattggaaaaccgtcagtgtggtcttcctcagagc
cagttttacaaaacatgcgattctgttgtagaggaaggcctgcatttggaaactggaatc
ccttcttccctggaaagaaaggtgttccctgggattcaactggaactagacggacctccc
acgggcattcgtcccttaggaaatcaatcagcaaccagcagggcacaccccgacagcgat
ttggcggtatttcactttcattatgagcttgaccgaagaatgtcggacagtgtctgtacc
ctatcagacaacttgattttggatgattgtggaaactgtgtatcactgcctgatgttggt
agggagcaaaagaaaaattatatggcatatacttgcaaactgatggaattggcaaaaagc
tgtgataatgagaacaagcagcgacagggtgatcattgtgacgccttgaacgatgaatat
atgtgctgcgaagcttcctgccgaaaggccaacgtggtatgttctagtgacagcttctgc
agggagggttttactgatagtccatctgccgagacttttctgagccattttgaggacttc
cctgataattgtgaagacgtagaagattattttaaaagtaaaaaggagcgatccactttg
ttagtgaggagattttgtaaaaatgacagagaagttaagaaatctgtgtatactgggaca
agggcaattgtgaggactctgccttctggtcacattggactggcagcttggagttacatt
gatatgaagagaagtggaagctcgttgccttgtgggagagtaacgggccagctatcaaca
gtgctaattaggcaagatgggagcccatgtctgtcagaagcccagtggtatccgatctac
aatgcagtgagaaggggagaagaaacagaagatacaattggatctcttctccatttcttc
acaaagctcccagcctctgagacagcctatgaaaggattaatgttggtccctgcttaaag
caatgtgtccgagacaccgtatgtgagtaccgcgccaccctccaacggacctccatatct
cagtacatcacgggttctctcctagaagcaaccacatctttaggagcaagaagtgggctt
ctcagtacttttggaggatccaccggacgaatgatgctgaaagaacgccaaccgggcacc
tctgtggccaattccagtgccctcccttcaagttcagctgggatcagcaaggagctgatt
gatctgcagcccctcatccagttccccgaggaagtcgccagcatcctgatggagcaggaa
cagaatatctaccgaagggtcttgccggttgactatctttgcttcttgacccagaacttg
agcactccagaatgtcagaggtccctgccctgcctcaaagcatccatctcagcatcaatt
cttaactcccagaacagagagcacaatgcccttgaagatcttgtgatgagatttaatgag
gtgagctcctgggtgacgtggctgatcctcacagccggctccatggaggagaagcgggaa
gtcttctcatatttggtgcatgtggccaaatgctgctggaacatgggcaactacaacact
gtcatggagttcttggccggcctcaggtcaagaaaagttttaaaaatgtggcagttcatg
gaccagtctgacctggagaccatgaggagtctgaaggatgccatggctcagcacgaatcc
tcctgcgagtacaggaaggtggtgacgcgggcgctgcacatcccgggctgcagggtggtc
ccgttctgcggggtgtttctgaaggagctctgcgaagtgctggacggcgcctccggcctc
gtgaagctctgccccagatacaattcccaggaggaaactctagagtttgtagctgactac
agtggacaagataattttttacaacgcgtgggacaaaatggcttaaagaattcggaaaaa
gagtccaccgtcaacagcatctttcagatcatcaggagctgcagccgcagtctggaggcg
gaggacgaggacagccccagtgaggggagcggctctcggaaaaactccctgaaggacaaa
gctcgctgccagtttgtaattggagatttactggatacagaaaatgacatctttgagcag
cccaaagaatgggaccctcatggattagaagagccacagaaggcctttgaccacgggata
gagctcatcccatggtacgtgctgtccatccgagctgatgtgcaccagttcctgctgcag
ggggccacggtcatccactatgaccaggacacgcacctctctgcccgctgcttcctccag
cttcagcctgacaatagcaccttgacctggacaaagcccaccacggcctccccagccagt
gcaaaagcaaaacttggtatgcctactgccacgtccgagcctggcaaattcccgttactg
ggcaatgctggattaagtggcctggcggagggggtcttggatttgttttccgtaaaggct
gtgtacatggggcaccctagcattgatatacacactgtgtgtgttcagaacaaactgagt
agcatgtttctctcggagactggtgtgacactgctctatgggcttcagaccacggacaat
agattactgcactttgtggcaccaaagcacacagctaaaatgctcttcagtggattgctg
gaactcactaaagctgtgagaaagatgaggaagttccctgaccaaagacagcagtggctg
cggaaacagtacgtcagcctctatcaggaggatggacggtatgaaggcccaactttggct
cacgctgtggagttgtttggtggcagacgatggagtactcgaaaccccagccctgggaca
tcagcaaagagtgccgagaagcccaacatgcagaggaacaacaccctgggcatcggtact
gccaagaagaagaagaaaatccttatgaggggtgagagtggagaggccaccgacgatgag
atggccacccgaaaggccaaactgcacaaagagtgtcgaagctggagtggctctgatcct
caggacattaacgagcaagaggagtcagaggcgaatgccatcacaagcccgcctaaccct
ctcccttccagaagagcccattctctgactacggctgggtcccccatcttggctgccggg
acgtcatctcccatcaggccagtgtcctcccctgtgctgtcttcaaacaagagcccgtcc
agtgcctggagcagcagcagctggcacggccgcatcaaaggaggaatgaaaggcttccag
agcttcatggtttccgacagcaacatgagttttgttgaatttgtggagctgttcaaatcc
ttcagtgtaaggagccgcaaggacctgaaggatctcttcgacctctacgccgtgccctgc
aaccggtcgggctctgagtcggccccgctctacaccaacctaaccattgacgagaacacc
agtggtcttcagcctgatctagatttgttgaccagaaatgtctcagatttggggctgttc
attaagagtaaacagcagctgtcagacaaccagaggcagatctctgacgccattgctgct
gcaagcatcgtgacgaatggcactggggtcgagagcacatccctgggcgtgtttggggtc
ggcatacttcagctcaatgacttcctagtgaactgccagggagaacactgcacttacgat
gaaatcctcagcatcatccagaagtttgagcctagcattagtatgtgtcatcagggccta
atgtcatttgaaggatttgcaaggtttctgatggataaagacaactttgcttcgaaaaac
gatgaatcacaggagaacattaaagaattacagctgcccctctcctactattacattgaa
tcttcacacaatacctacctcacaggccatcagctcaaaggagaatcctcagtagaactc
tacagccaggtcctcctgcaaggctgtaggagcgtagagttggactgctgggacggagat
gatgggatgcccattatttaccatggacatacactgacaaccaagatccccttcaaggac
gtgatcgaagccattgatcgcagtgccttcatcaactctgacctgccaatcatcatatca
attgaaaaccactgttcattgcctcagcaacgaaaaatggcagacattttcaagactgta
tttggagaaaaactggtggctaagttcttatttgaaagtgatttctcagatgatccaatg
cttccttctcctgaccaacttagaaggaaggtacttctcaaaaataagaagctaaaagcc
caccagacgccggtggatatcttaaagcaaaaggctcatcagttagcatccatgcaagct
caggcttacaatggtgggaatgtcaaccccccacctactaataatgaggaggaggaagat
gaagaggacgagtatgattatgactatgaatctctctctgatgcagatgtccttactgct
tctcctgctcctaactgtcaggaagataacattctagaagacagacctgaaagcaaatcg
tgtagcgacaagcttcagtttgagtataatgaagaaatccccaagaggataaagaaagca
gacaactctgcttgcaacaaaggaaaggtgtatgacatggagttgggagaagaattttat
cttcctcagaataaaaaagaaagcagacagattgcaccagagctttccgaccttgtcatc
tattgccaagcagtaaaattcccaggcctgtcaactctaaatgcatctggctctaacaga
ggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggcagaatgagccct
ggggagacggcatcacttaacaaaacatctggaaaaagttcctatgaaggaatgcgacag
gcctgggaggagtcttcttctcccctcagcccagccacgtccctcagcgctatcattaga
actcccaaatgttaccatatctcatcgctgaatgaaaatgccgccaaacgtctgtgtcgc
aggtattctcagaaactgatccagcacaccgcctgtcagctgctgaggacttacccggct
gccacccgcatcgactcctccaaccctaaccccctcatgttctggctgcacgggatacag
ctcgtggcactcaactaccagacagatgatctccctttacatttaaacgctgccatgttt
gaggccaacggtggctgtggctatgtgttgaaacccccagttctgtgggacaagaactgc
cccatgtatcagaagttttctcccctggaaagagacctggacaacatggagcccgccgtc
tactctttgactattgtctctggccagaacgtgtgcccgagcaacagcacaggaagcccg
tgcatcgaggtcgacatcctgggcatgccgctggacagctgccacttccgcacgaagccc
atccaccggaacactctgaaccccatgtggaacgagcagtttttcttccgggttcacttt
gaagacctcatatttcttcgttttgcagttgtggaaaacaacagctcggcggtcactgct
cagaggattatcccgctcaaggctctaaagcgaggatatcgacatcttcagctgcgaaac
ctccacaatgaagtcttggaaatctctagtttattcgtaaacagcagaaggatggaagaa
atctcctctggcagttccgtgccggcctctttgatgtttagtacagaagaaagaaagtgt
ctgcagactcacagagtcacggtgcatggcgtcccaggtccggagcccttcactgttttc
tctataaatggaggcaccaaggcaaagcaacttctccagcaaattctgaccactgaacaa
gacaccagacctattgccgcagactactttttgatggaagaaaaatattttatatctaaa
gaaaagaatgaatgcagaaaacagccgttccagagggccattggtcccgaggaagagatc
gtgcagattttaagcagctggtttccagaagagggctatgttggcaggattgtcttaaaa
acccagcaggaaaacctggaagagaaaagcattgttcaagatgacagagaggtgatcttg
agctcggaggaggagagtttctttgtccaagtgcacgacgtttctccagagcagccgcgg
acggtcatcaaagcgccgcgcgtcagcaccgcacaggacgtcattcagcagaccttatgc
aaagccaagtactcctacagcatcctgagcaaccccaacccgaacgactacgtacttttg
gaagaggtggtgaaagacacagccaacaagaagtcttctacccccaagtcctcccagcgg
gtccttttggatcaagagtgtgtgtttcaagcccaaagcaagtggaaaggtgcaggaaaa
ttcatccttaagctaaaggagcaagtgcaggcatccagagaagacaagagaaaaggcatt
tcttttgcaagtgaattcaagaagttcaccaagtcaactaaacagccccgaggactcaca
tcaccttctcaggtcttggtttcggaaagtgtccaaaacaaagaggagagacctgtgggt
ggcagcgacacgatggactatcgacagtga

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