Maylandia zebra (zebra mbuna): 101464456 Help Entry 101464456         CDS       T02814                                  Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism mze  Maylandia zebra (zebra mbuna) Pathway mze04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:mze00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     101464456  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:mze03036]     101464456 Chromosome and associated proteins [BR:mze03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     101464456 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin SYNE1 Spectrin_SYNE1 KASH Pacifastin_I Motif Other DBs NCBI-GeneID:  101464456 NCBI-ProteinID:  XP_023011206 LinkDB All DBs Position LG15:complement(11427017..11519157) Genome browser AA seq 7407 aa AA seqDB search MIFVWWERFSSESAAFFLWINQKQKELDAVNIFSSSDPLDKHISAVEAVGEALEERKAVL VLMEADCEALSRFVTSGEAGRIRAQLNQTRQYWEELKGRAEQLGVQLNQSASYRQRCNDN LEQVKKTVSDLNEKLDCLITCCVSSLETYKALQDHIEVCQTVELLKPRLMALCSATKRLG EGSQLEEEVANLQKQQRELMEKASEKKSMLESLLALWQRYEKENLSMKSWLDRCESVCCP DTELLSADKVKLRNELQNVQEMQVETVSHETLLQGLVNLGLCLYPTAPEARIQELSDDLT QLQERCASVKNSILRRIKRLKLQLEHLEQFDQALLPLTQWSENFLSLLRSSSQVDIADLE AVFIKLKEHEAQLQENASLRETLHKKESFLLCSSTPEAQEQLQAWREDCLQPLSESQRLL LLRKECLSELNTFLEKHKMAAKAVRRLHEAVEGRGSWDPSKAEELHREIGEVAKEVARLE AEAVGLDGQLSKAHLHLCGAEWRGSKDASHPQGRTSCRGQAVALTMALEEVQRGVGWRQS EADALGALWSSFRERREEVMKNLKKLLDDARQEGIRESSVQAFHNRMRFFVQLEDELQSL QHSQRWLEEKGNQLAQRDSELAGEALREVALVKTAWDNVRTLIINSQEHSGVVLDLLRQF HHLKSILTTLMESAQAVAHNLPDHNHSAQEAKRTFTQHKAIKDELREKQEDMDQLIRTVE DLQRELEKVPNCEMSSIQRDTETLREQWLTIAEKIQTNTERLGYCVKLWDDLKAAEHDIN QWTSGSIADLTDAVASLSDKEKTEAQLASFQEEVEKREHMLDVLEERVADLKARAKLQEI PLQMQVLQSDLRKKMAHAEEVYNQAKHTLTYFSFQKERLEDLMSQMAQRLEAVEGSLSDL TETTSPEDIGTVKDLQSVVQQQRADMDSARDALTALCRSHPSEELSRLSSDLTSIAKRTE TVSQRCAKTRGNLQDGLQLHFNELVQDFKSWLAILKLELKECSNPSGDVVLLGAKLQRLK VSLQRISEGEERLSQVSKEAGKLQLHLPKAGAVQVQENLSACQREWRSFLDGCYQSKLDL EESVGLLKNFDDCVQGIRDWLKQMDLSLKAEPVLGGESQQGAPDTTEELERMEQLHKELT ERRESIEQLCQEAQALSEAGRGSGGEVRVTGQLQMEHQALLKAARERLRGCQESQAFGDT LQGVWAWLEEIQERLGTVDSTMGTKEQLEQRLETVQDILLLKGEGEVKLNMAMGKGELAL RSYGAAGQEVVRSQLQELEDAWATLLVTAMSCHSRLEWTVSQWGGYLESAAQLRCWMEVV EREVCAPLTPQPGPREKASQLERLRALLADLEDHQMALSTLEEKARELFKKTGDASFNHG ARTQLQVQFDNLTALVEERVRLAQAVVLEHQNYLEAVRELTDWLMTAGEELQHWSDTSGD STSIKKKLSEVRERVECRLLEGRDRLSRVRRSAASTAEHTAAGGCEAMDRQLGALSHALE QWEGAALRARDSLEGALSAAAASEEEYNRLTAQLEEELKVFDGRLRGWSQELVKAEGQSN GEEAVEGWQLAKDILEGLQSAEPMAEKLKGQLNDLVRYSRDLGSQSDRVTALIKQHNSLS LRASRECQNKERLLEQRFRAALRDFQQWLVNAKISTAKCFDVPQTVTEASSALQRIQEFL SDRENGQARLSTVGASGELLMAVVSKDRVEGIKAKVANAREDWKSLMNNLQMREDALKNL QAQMTEFEASAEPLQEWLNSTEVRVQESSARLHDLPAKKQELSKLQCVLEEMACQEVELG RLRERAHRLWEGQAAGKGFVHRVSQLSAQYLALSNLTKDKASRIERIVGEHRLFSEGLKE LQDWVCEAQRVLNTCISTTTDKGLLEDRMLQLEALLTARQEREIQLKMLLTRGEAVQRNT SAEGVPVIRKQIQDLKDSWDSLLSASIQCKSQLEGALSQWTSYQEDVGQFMQWMDRVEET LSCSDRQYSEMRDKTANLGKTKLLYEEVLSHSSPLETIATKGSNMTEHHTTQQEVQQLQC RYNSLKEKAKNAVSKAKELVLVHQEYQRGLHVFEDWLEKEQASLASLSHPEGNVDTLENT LQQLQNLQEHCSNGQALLSAVLTSRERVIPWGIPQIEDRALDTAQREWAAYQSRLKETQG QLHSMLTRLRQMGHKFLSLAQWLEEMERVANIRSNRRSDATTKQIQLKKLQGCLEAVLTR QSEVDGLSSLAQEVLEETYISSRISVTATQLTARYHSLLLNIQDTIKQLQEELRSIEETE NLCKSFTEWLGSTLKSFTALTDTSEPLDQAAMEKKMKKLESLQSELQHGHSFLKSLRERA EQAAGFLNESAAESLGGEVEARLSQLEELAGGLRQERSFLERALLLAKEFQDRYKAQAQW LVETKALLRTPVEPKAELYQRRAQLTKYKALLQMVQSHDGAIKSVLEKGDALLSSVHYPS IRDKISKLQKDYTGLCNTALAHVENLEGQVKEQEAYHNELQEVERWLLQMSSRMVTPDPS ISGSLEAATQQLARHKAIMEEIAGFEDRLAGLKERGDHLMEGCSDRVQSRLRQQVQAHQQ GTRDSYSAICSTAQRVYQSLDHELQRHVSLQDTLQQCQTWLNSVSEEPEPPTHPSFSLEE ALQQVKQERALQEQAGTYLQLVCATCDLCEPRVRETAAAIQQVKLQIEERMLLCEEVADS WRDIEEQKADLETQLIETEQQLQNLTRRPAELEPKIAQNQLDKAQEFLQQIKEKQSEVTR LHEAIGRLMDGQVSPALEEIRRLKKSWMDLGQRAEELEALRGEDMQRSGEYQESVVAVEE LFHQVSREWDYLARADTESTSEHLEALRKLASDLEEQRETLEDLRDQRQAILPRLSLLDK ELVKQQVGHLEQRWAQLESLIQQKIQDSAQMLEDLARVENQLRDAREWVEEQRPALTSAL KTSPPPDLAQSFLFDHLSVCVELEARQQLLGQAVKEAQAVASRLGLSEKRRLQELVEQAQ TEVEALGARVAQRRKYLSKAFTERTQFLQGLGRALSWIQQQERKALIDDHIALLPEDLAK QVAGCRGVQSSLRAYQRELASLWVQGRDLERDATDKERAETLARLEELQSAFETALQRTT QRLAALEKALTSRKYFQVDLDKTCQWLRQADDITFPEINLSTADDSSDLQSQLSNYQNVL EQASEYENLLLIVQRIGQEILPTLNEIDHCYLDERLNALPQQYNAILALAKEKKDRVQQI ILERKEFCTFFDITRNALEELQEQFDNLEKQTISIEEEEVVSLVNEYRNINESLVHISPA VRELHGKNEGFLSKGQHYRAEETQQLVSLHNTLKRRIDQKIKHLHDCLEILSKHKVVFSK LDSELQSAKEELVKLKSDKEVSAIDKISSLYLLLENLDGVNSQAEECNQQMQNLCLTTDA AAFQETSLQLQSLQSLRCDAKRFVEESETTVAKNEDFTRAVEKVFEWLRTVKDKTKDPLT FSEVKIERIHEEVRKLKIKEEEVKSRLRVVDVLGAREKQKYKSRKATVPSHVEEKLQELG RLGDEVQQGICAKQLAVDQALSLVQRHHLSLQSMQKWLDSAAALLQRATTGVELENQADC AQDLEEILAKEKNFKTGLQEFGTLDPLLVDFLEAGVMSGLREKVNTMQLRSTEVKQQVDT YREVLERCAALWSSFQREKETVVEQMNDSEGRMAMFTTAKAVSAHQAEDKCQRYKSLVAH VDLLEMPLNALKERAAELEQLISESSKAITSHVVSSLWQRWTRLRSVARAQERALEDTAR EWRNFNEKMEKVRSVSIDLHGRVPDSTVEKAATRAALQSLLEYHDSFSLEVEREQSILAL LGQQSCSLRGEDDKVEVMEKSTENGHKETPCSQEIQSMQAQYDSLVLQVRASRTQVHQEL REREEVEKELGLVKGWIQDTRGLLLSPTADLDSLLQELETAHGEVISRRQSVERMTELQQ SKYQDLQAGLPSELSMQLAEVALALGSAEDQVQAREREVQQTRDVKEDFSSRLQDIEAKL KTIALKLEDKGADLEEAKEDTKALSEECESCGCSLAELGVAVQEFGEQNPLLCKQLGDAV AKLTEVQHHTSQQVQDRANRLKKAERQVEEYQGMKAFILSWTKKAEALVTGNIIWSSASQ LQEQIRAHQALLRECRGLHGDLEAMGEREVQLADVLQTEGWSQRVKHLSRRTEELQQTAK TRLQSLQDAAKDMLRLEAEVKSLHAAVDQIQATLASPELNKLSLREQLTQRQRLLVEMEG FKQQVAAVQQCQSALRLPEEVVASLPICRTAQTLQQEASQVQHTTIQQCNILQEAVVQYE QYEQEVKNLQRLIEEAHRIIQDRPVSTNNIQELQAQIHHHEELAQKIRGYQEQIASLHSK CKMLTVKAKHATMLLTVSEVEGFSDGMDELSDEELPSAVTDTTTADAKQLPAHPSVVMMT AGRCHTLLSPVTEESGEEGTNSEVSSPPACRSPSPGANAEAALNQGRGTLSRVPLQELYD PSMESSAANLDDLQRSWETLKNVISEKQKSLYEALERQQHYQESLQSISIKMESIEGALN EGLEPNKTPESQMAAHQALMDEILMLQDEIGELQMCFSEELAESDGDAGEQLALQSTLTV LGERMATIRMKASGKRQLLEEKLSEQLEEQRQEQALQRYHSEAEELDNWLLSTRATLSSA LQPQNEDMDMEEQLIDCQNMLYEIEQKVSYLSELSVHSESLLLEGRAETKGEAEQLTLKL RSLKDSLLELQQMLQDKQVDIQGSLQEQEDSEPDSSLSQSPNVQDWLSQARSTRTQQQHD NLRRQKELQEHVAEQRKLLKSVASVGEELLGQQTTPNGDSEVSVPGGVLLENETLSPLEQ LRQRWENLNNDQNTKLQLSLNSLEQDQLSPVLHRSRLSSPSVVFRGEATSQDSCSPRASF EACSQTLERITEEAAGSESKLAASLGGATIQQDLYAAVSAASSWLDAAENQLLAGPVLLS EDTETQLTHLEGLNKQLKEMTREVKNCRDLLGGGLDRLCGGEERALMEDTLEGLQERMGL LDSALEQHCDAMRDRLQEHSAFQNELRLLFTALTESKHQLLHKMAGTADRPASKQIETLS EVEDSLKEFEQKVTELKTKAEGLQSDSSSNQELLKLQDAYEELVLMVGSRRSSLNHGLSL KAQYEAALHDLNDLVDTAQDKMAADQKMTVASVIEVQMLLDKHKEFFQGLECHMILTQTF FSKVSGLVSQRESQTLEETMALAHSVLKQAHRRGVELEGILESWSRLVEDYQALCRQLEA VECSIPTVGLVEETEERLTERISLYQRLKASLTEHQPQLYQVLEEGKKLFLSVGCSDLEN QLTQLGEHWLSSTTKVNKELHRLDSTLKHWTRYQSESAELSHWLQSALDRLEFWTTQSVT VPQELETVRDHLCAFLEFSKEVDAKSSLRSSVLSTGNQLLRLKRVDTAGLRTALGQVDTQ WAELLTRIPVVQEKLHQLQMEKLASRHAITELMSWISLMENIIEEDQDKIMAAVGSAVVQ DYLQKYKGFRIDLTCKQLTVDFVNQSVLQISSQDVEGKRSDKTDFAEKLGAMNRRWQILQ GLIAEKIQLLEGLVEGWLEHENGVQALKTWLTVQEEKLKKRQRIEDVASVQSALKDCQEL EELVKEKEKDLEKAEERGNALIQDKKGAACCVVKETLKGLNQSWAHLDHMISQMKVSLRL VLEQWTLYRRASEEINGYLMEGRYSVSRLRLLNGSLEAVQQQVESLESLQEEMDKQESSL RKFGSITHQLLTECHPSVAETLNKALRDVNIRWNLLLEQISEQLRTSKSLLGLWQRYRSL YSQCVTAVHKQEERADRLLRSATDREITEDESSAWIKDCNDCLCDQDAVQQSLQQLQALG EQLRSQVDSSSAASLQSDHLSLTHRLAALEHALHRQQDVLQCGSVTCGVFREQLDKLICM AEEAEEVLKDSDPVGSPDLNVVQTRIEKLKGHLLKLSSLSPDLERVNEMVYRIPVSDRDI KRLQSLNRAWATHSAHLTERFSKLQSVLLQQQSFLEKCEAWMDFLTQTEKKLGAEISGNY QSLLEQQRDHELFQAEMFSRQQILYSIISDGHRLLDQGQVDKSYDFSVKLALLSNQWQGV VRRAQQRRGIIDSLVRQWQNYREMAEKLLRWLQEVTRDPDVHQPGEPVALQQARNLLDQI QLRERVLQRQQGGYILTVEAGRSLLLSADAKAESTLQTELMEIQERWRHAHHRLDQQRRQ LQGLLKNWERCEKGIDVSLEKLRAFKRKLSVPLPDHHEELHSEQIRCKELESSVEGWTDD LTSLFLLRDSLEGVVSADDITVLQERLQLLQRQWEEVCHQLSLRRQQVSEKLNEWAVFNE KNKELCEWLTQMESKVSQNGDISIDEMIEKLRKDYQEEISVAQENKQQLQVMGERLARAS QDSKATEIQHKLNKVSERWQHLLDLIAARVKKLRETLVAVQQLDKNMSSLRSWLAHIETE LSKPIVYTTCDDQEIQRKLNQQQELQRDIEKHSTGVASVLNLCEVLLHDCDACSTETECD SIQQATRGLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKTSEKTAALPNS SGVLYTVAKEELKKFEAFQRQVQEFLTQLELINKQYRRLARENRTDSSCRLREMVHDGNR RWDNLQKRVAAVIRRLKHFISQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIK QLRAFQQEIYLNTGKIELVFRQGDALIEKSEPLDAAVIEEELEELQRYCQEVFGRVDRYY KKLTRLPLADDELDGSDRELDMEDGGDLSEMQWSDSSLPRTSARPASGTVALVRADRSGR DTPASVDSIPLEWDHDYDLSRGLESPSGRGNGERSQGQEDEDEYMRTAATALSDVVIPES PEAYIKLTEKTLKSSSGEPGQLEASLRQLDQALDAGRYHLQQREATANRVSPDVDSTYMG YMRLMGECRSSIDAVKRAEGELTEDEDEMPGLTNPTNTDTQSAGVIERWELIEAQSLSEK HKHKQNLQQWQQLISDLQTLRAWLGHSEAELSQLRGLDLSTDIHTIQQRIKKLKELQKGM DAHKAEVLSINLSSADFLQSEPDSEEAWELRDRLKEMNSRWDRLGASLEDWREELQRALM QCQEFHEMSHGLLLWLENIDRRRNEVVPIPQKANRETLRAHHKTLMQIKCELLDSQQKVS SLQELSAQLLVNIKPQSLAQTSERTQAQGNECLEAQEKVHVIWNRLRLLQREVNSDLEGL ERRLGAMDAEQDCSPLPVSRSTAPGSDVTSQTRKRLPRGKSSQAHPGHPESSPRHSRSRS PGAAGCVSSRSDLSDVTSSASSSSSKDKSFLLRVLRAALPVHLLLLLLIGLACLVPMTEE DYSCHHANNFARSFHPMLRYTNGPPPI NT seq 22224 nt NT seq  +upstreamnt  +downstreamnt atgatatttgtgtggtgggagcgcttcagcagtgaatcagcggccttctttctttggatc aatcagaaacagaaggagctggacgctgtcaacattttctcctcctctgatcctttagac aaacacatcagcgctgtagaggccgtgggggaagctttagaggagagaaaggcggttctt gtcctcatggaggccgactgcgaggctctgtccaggtttgtgacttctggagaggccggt cgcatccgggcgcaacttaaccagacaagacaatactgggaagagctgaaggggagagca gagcagcttggcgtgcagctcaaccagagcgcctcctacaggcagagatgcaatgataac cttgaacaggttaagaaaacagttagtgatctgaatgaaaaactggactgtctgatcaca tgctgcgtatcatcattagagacctacaaagccctccaggatcacattgaggtctgccag actgttgagcttctgaagcccaggcttatggccctgtgttcggccacaaaaaggcttgga gagggcagccagctggaggaagaagtggctaacctccagaagcagcagagagagttaatg gaaaaggcttcagaaaagaaatctatgttagagagccttctagctctgtggcagagatat gaaaaggaaaatttgtccatgaaaagctggctggacaggtgtgagtctgtgtgctgccca gacaccgaactgctctctgcagataaagtaaagcttaggaatgaattacaaaatgtgcag gaaatgcaggtagagacggtgtcacacgagactctccttcagggtctcgtgaatctcggc ctttgcttgtaccccacggcacccgaagctcgtatccaggagctcagtgatgatctcaca caactacaggagagatgcgcttctgtgaagaacagcatattacgcaggataaagcggttg aagctgcagttggagcacttggagcagtttgatcaggcactgctgccccttacccagtgg agtgaaaacttcctgtctctcttgagaagctcttcccaggttgatattgctgatcttgag gctgtgtttattaagctgaaggagcatgaggcacagctacaggagaatgcatcactgaga gagactctccataaaaaagagtccttcctgctttgctcttccaccccagaggcccaagag cagctccaggcatggagagaggactgcctgcaacctctcagtgaatcccaacgtctcctg ctgcttcgtaaagagtgcctgtccgagttaaacactttcctcgagaagcataaaatggct gctaaggccgtgcgtcgccttcatgaggctgtggagggcagagggagctgggacccttcc aaagctgaagagctgcatcgcgaaataggagaggtggctaaagaagtggcccgactagag gccgaagctgtcgggttagatgggcagctgagcaaagcacatctgcacctgtgtggagca gagtggaggggatctaaagatgccagccatcctcagggaagaacatcttgcagaggacag gcggtggccctgacaatggctctggaggaggtgcagaggggtgtggggtggagacaaagt gaagcggatgctttaggggctttgtggagctccttcagagagagaagagaagaagtgatg aagaatttgaagaaactgttggacgatgcaagacaggagggcatcagagagagctctgta caggcctttcacaacaggatgcgtttctttgtccagctggaggatgagctccagtccctg cagcactcgcaacggtggttagaagaaaagggaaaccagctggcccagagagacagtgag ctggcaggagaagcactcagggaggtagctctggtgaagacagcctgggataacgtcagg acgctaatcatcaacagtcaggaacacagtggagttgtgttagatcttcttcgccagttc caccacctgaagtcgatcctcaccacactcatggagagcgctcaggccgtcgctcacaat ctgcccgaccacaaccacagtgctcaggaagccaaaaggactttcacgcaacataaagcc ataaaagatgaactgagagaaaaacaggaagacatggaccagctcatcaggacggtcgag gacctgcagagggagctggagaaggttcccaactgtgaaatgtcctccatccagagagac acagagacacttagagagcagtggctgacgatcgcagagaaaatacaaaccaatacagaa agattaggctactgtgtgaaactctgggatgacctcaaggccgcagagcatgacatcaac cagtggaccagtggatccatcgctgatctaactgacgctgtcgccagtctcagtgacaag gagaagacagaggcccagcttgcgtcctttcaggaggaggttgaaaagagggagcacatg ctggatgttttggaggagagagtggcagatttgaaggctcgagccaaactgcaggaaatc ccattacaaatgcaggtcctgcaatcagatctgaggaagaaaatggcccatgctgaggag gtgtacaatcaggccaagcacactctgacctacttcagtttccagaaagagcgactggag gacctcatgtcccagatggcccagcggctggaggcagtcgagggttccttatcggacctc accgaaactacttcccctgaagacattggcactgttaaggacctgcagagtgtcgtgcag cagcagagggcagacatggactcggctagagatgccctgactgctctgtgcagatcgcat ccctctgaggagctgtcacgcctctcgtctgatctcacctccattgccaaacgaaccgag accgtttcccaacgctgtgccaagaccagaggaaacctgcaggacggtctgcagctccat ttcaacgagcttgtccaagacttcaaatcctggctagcgattctcaagttggagctgaaa gaatgctctaacccgtcaggagatgttgtcctcctaggagccaagttacaaaggttaaag gtatcacttcagcggatttcagagggtgaggaacgcctctctcaggtttctaaagaggct gggaaactccagctccacctacctaaagctggagcagtgcaggttcaagagaacctctct gcctgccagcgagagtggaggagctttctggatggttgttatcagagcaagctggacttg gaggagagcgttggccttctgaaaaattttgacgactgcgtgcagggtataagagactgg ctgaagcagatggatctcagtcttaaggctgagccagttcttgggggagaaagccagcaa ggtgccccagacaccacagaagagctggagaggatggagcaactccataaggaactgaca gaaagaagggaatctattgagcaactctgccaggaagcccaggctctatctgaggcaggc cgcgggtcaggaggagaggtcagagtaacaggccagctacagatggagcaccaggcccta ctgaaggcagccagggagaggctcagaggctgccaggagagccaggcttttggagacact ctccagggggtttgggcctggctggaggagatccaggagcgactgggtacagtcgacagc acgatggggaccaaagagcagttagagcaaaggctggagacggtgcaggatatcctgctt ttgaagggagagggtgaggtcaagttaaatatggcaatgggtaaaggtgagctcgccctg cgcagctatggcgccgccggacaggaagtggttcgctctcagctgcaggaactggaggac gcatgggctacactgcttgtgacagccatgagttgccacagtcgattagagtggactgtg tctcagtggggaggataccttgagagtgccgcccaactgcgctgctggatggaggttgtg gagcgggaggtgtgtgcccctctcacccctcagccaggacctagagaaaaagcttcacag ctggagagactccgtgctctgctggctgatctagaagaccaccagatggcgctgtccaca ctggaggaaaaagccagagaactcttcaagaagactggtgatgccagctttaaccatggt gctcgcacccagctgcaggtgcagtttgacaacctcacagctttggtggaggagagagta cgtctggcacaggcagtggtgttggagcaccagaactacctggaggccgttagagagctc actgattggctaatgactgcaggggaggagctacagcactggtctgacacatcaggagac tccacatccatcaaaaagaaactgtcagaagttagggagcgtgtggagtgtcgacttctg gagggccgcgaccgcctcagccgggtacgtcgcagcgcggcgtccacagcggagcacacg gcagcgggaggctgcgaggccatggatcgacagctgggggcgctgtcccacgctctggag caatgggaaggggccgctctgagggcccgggatagcttggagggggccctgtccgctgcc gcggcttccgaagaggaatataaccgtctgaccgcccagttggaggaagagttaaaagtg tttgatggacgtctgagggggtggagccaggagctggttaaagctgaagggcagagtaac ggcgaggaggccgtggagggatggcagctggctaaggatatactggagggcttgcagagc gccgagccgatggcggagaagttgaaaggccaactgaatgacctggtgcgatactccaga gacctcggctcacagtcagaccgggtcacggcgctaatcaaacagcacaacagtctgagt cttcgtgcatccagggaatgtcaaaataaggagcgcttgttggagcaaaggtttcgtgca gcccttagagacttccagcagtggctggtcaatgccaaaatcagcactgccaaatgcttt gatgtgccacagactgtcacagaggcctcctctgctttgcaaaggattcaggagttcttg agtgacagggagaatggccaggccaggcttagtacagtaggagccagtggggagctgctg atggctgtagtgtccaaggacagggtggagggaatcaaggccaaggtggcaaatgcgaga gaagactggaagagcctgatgaataacctgcaaatgagagaagatgctctcaagaacctg caggcccagatgacagagtttgaggccagtgctgagcctctgcaggaatggctgaacagc acagaggtcagagttcaggagagcagtgctcgcctacatgaccttccagccaagaagcag gagctcagcaaactacagtgtgtgctggaggagatggcgtgtcaggaggtagagctgggc aggctgagggaaagagctcatcgactctgggagggacaagcagccggaaagggcttcgtc cacagagtatctcagctgtcagcacaatacctagccctcagcaacttaaccaaggacaag gcatccaggattgagcgcattgtaggggaacaccgccttttctctgaaggactgaaagag ctccaggactgggtgtgtgaggctcagcgggtcctcaacacctgcatctccaccactaca gacaagggcttgttggaggaccggatgttacaacttgaagccttactaactgcccgtcag gagagggagatccagctaaaaatgctcttgacgcggggagaggcagtccagaggaacact tcagctgagggagtcccggtgattcgcaaacagatccaagacctcaaagactcgtgggac tcactgctgtctgcctcaatccagtgtaaaagtcagctggaaggtgctctgtcgcagtgg accagctatcaagaggacgtgggtcagtttatgcagtggatggatcgggttgaagagacg cttagctgctcagacagacagtactctgagatgagagacaagactgctaacctgggaaag accaagcttctctatgaggaagtactgagtcatagcagtcctctggagactattgccaca aagggttccaatatgactgaacaccacacgacacagcaggaggtgcagcagctgcagtgt agatacaactccctcaaagaaaaggctaagaatgcagtcagcaaggccaaggagctggtg ctggtgcatcaagagtatcaaagggggttacatgtgtttgaggactggctggagaaggag caggcctctctggcctcattgtcccatccagagggaaacgtggatacacttgagaataca ctgcagcagctacagaacctgcaggagcactgttcaaatggccaagccttactctccgct gtgctcaccagcagagagagagtaatcccctggggtatacctcagattgaggaccgagcc ctggacaccgctcagcgagagtgggcggcctatcagagccgtctaaaggagactcaaggc cagctgcactcaatgctgacccgactgaggcagatgggacataaattcctgagcctggca cagtggctggaggagatggagagggtagctaatatcagaagtaatcggaggtcagacgca accaccaagcagattcagctgaagaaactccaggggtgtctggaggcagtgctcacacgg cagagtgaagtcgatggactttcatctttagcccaggaggttctggaggaaacttacatc agcagtcgtatcagtgttacggccactcagctcactgcccgctaccactccctgctgctc aacatacaggacaccatcaaacagctacaagaggagctgaggagcattgaagagacagag aatctttgcaagtccttcaccgagtggcttggctcgactctgaaaagcttcacagcatta actgacacttctgaacctctagaccaggcggccatggagaagaagatgaaaaaactagag 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gctttacagcaggtgaagcaggagcgggctctgcaggagcaggctggcacttacctccag cttgtgtgcgccacgtgtgacctgtgtgagccgagggtgagggagaccgcagcagctatc caacaggtcaaactgcagattgaggagcgtatgctgctttgtgaagaggtagccgacagc tggagagacatcgaggagcagaaggcagatctggagacccagctaatagagacagagcag cagcttcagaacctcaccaggagacctgcagagctggagcctaagattgcacagaaccag ctggacaaggcccaggagttcctgcagcagattaaggagaaacaatctgaggtaacacgt ctgcatgaagccatcggcaggttgatggacggacaggtctctcctgccctggaggagata aggagactgaagaaaagctggatggacctgggccagcgggctgaagagctggaagccctg cggggggaggacatgcagcgaagtggagagtaccaggagagtgttgttgctgtagaggaa cttttccatcaagtatccagggaatgggactaccttgctagggctgacacagagagtaca agtgagcatctagaagcactcaggaagctcgccagtgacctagaggagcaaagagaaact ctggaagacttgagggaccagagacaagctatcctgcctcgacttagcctgctagacaag gagttggtcaaacaacaggtgggtcatctggagcagcgctgggcacagctggaatcgctg attcagcagaagatccaggactctgcgcagatgctagaggatcttgcccgagtggaaaat cagctgagagatgccagagagtgggtggaggagcagcggcctgccctcacctctgccctg aaaaccagcccaccccccgatctggcccagagtttcctgtttgaccacctgagcgtatgt gtagagctggaggctcgtcagcagctgctcggtcaggcagtgaaggaagctcaagctgtg gcttccaggctgggactgagtgaaaagagacgcctgcaggagctcgttgaacaagcccag actgaagtggaggctctcggggctcgggttgcccaaaggaggaagtaccttagtaaggcc ttcacagagaggacacagttccttcaaggcctggggagagcattatcttggatacagcaa caggagaggaaggccttgatagatgaccacatagcacttcttcctgaggacctggcaaag caggttgctggatgtcgaggtgttcagagcagcttacgagcttatcagagggagctggca tctctctgggtacaaggccgcgatctggagagagatgccactgacaaagagagagcagaa acgctggcaagacttgaggagctacagtctgcttttgaaactgctctccagaggactacc cagcgtcttgcagccttagagaaagccttgacctccaggaagtacttccaggttgaccta gacaagacttgtcagtggctgagacaagcagatgacataacatttccggaaatcaattta agcactgctgatgatagctcggatttgcagtcacagctttccaattatcaaaatgtccta gaacaagcttccgagtatgagaacctccttcttattgtccaaagaataggtcaggagatc ctccctactctgaatgagatcgaccattgctacctggatgagcggctcaatgccctgcca cagcagtacaatgccatcctagctctagccaaagagaagaaagacagggtccaacagatt atcctagaacggaaagagttctgcactttctttgatattactcgtaatgcactggaggag cttcaggagcagtttgacaatctggagaagcagactatcagtattgaagaggaggaagtt gttagtttagttaatgaatacagaaatataaatgaaagtttagtccatattagccctgct gttagagaactgcacgggaaaaatgagggtttcctcagtaaaggtcagcactacagagct gaggagacacagcagcttgtgagtctccacaacacactgaaaaggagaattgatcagaag atcaaacacttacatgattgcttggaaatactatctaaacacaaagtagttttttccaag ttagactcagagttacagtctgctaaagaggagctggtgaaattgaaatcagacaaagaa gtaagtgccatagataaaatctcaagtctttatttactgctggaaaatctggatggagtg aactctcaggctgaagaatgcaaccaacagatgcaaaacctttgtcttacgactgatgct gctgcctttcaggaaactagtctgcagctccagtcgctgcagtctttacgatgtgacgct aagcgtttcgttgaagaaagcgaaacgacagtcgcaaaaaatgaagacttcacaagagct gttgagaaagtgttcgagtggttgaggacggttaaagacaaaacgaaggatcctttgacc ttttcagaggtcaaaattgagaggatacacgaggaagtgcggaaactgaaaatcaaggag gaagaagtgaaaagtagactgagggtcgttgatgtcttgggtgcacgagaaaagcaaaag tacaaaagcaggaaagcaaccgttccttcccatgtagaagagaaactgcaggagctggga aggctgggagatgaagtccaacaaggaatttgtgcaaaacaactggctgtggatcaagcg ctttccttggtccagaggcaccacttatctctgcagtccatgcagaaatggctagactcc gctgcggctttgcttcagagggccaccacaggggtggagctcgaaaaccaagcagactgt gcacaggatctggaagaaattttagctaaggaaaaaaacttcaaaactggtttacaggag ttcgggactttagatcccttgctggtggattttctggaggcaggagtgatgagtgggctc agagaaaaagtaaacacaatgcagctaagaagcaccgaagtcaaacagcaagtggatact tacagagaagtgttggagagatgtgcagctctgtggagctccttccaacgtgagaaagag accgtggttgagcaaatgaatgattcagagggcaggatggccatgttcactacagctaaa gctgtaagcgcccaccaagcagaagacaagtgtcaaagatacaagtcactggtggcgcat gttgacctgctggaaatgcctctgaatgctttgaaagaaagagcagcagagctggagcaa ttaatctctgaatccagcaaagctatcaccagtcacgttgtgtcgtcgctatggcaacgg tggacccgtctccgcagtgtggcccgagcccaggagagggcactggaggacactgctaga gagtggaggaacttcaatgagaaaatggagaaggtacgatcggtgtccatagacctccac ggtcgtgtcccagacagcacggttgagaaagcagccaccagggcggcgcttcagagtctc ctggagtaccatgactccttcagtctggaagtggagagggagcagtccatactggctctg ctggggcaacaaagttgcagtcttaggggagaggatgacaaggtggaagtgatggagaaa agcactgagaacggacacaaggagacgccgtgctcacaggagatccagagcatgcaggcg cagtatgacagccttgtgttgcaggtgcgggctagcaggactcaggtgcatcaggaattg agggagagagaggaggttgagaaagagctaggcttagtcaaaggctggatccaggacacc 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aagctcagtctcagagagcagttgacacagagacagcgtctgctggtggaaatggagggc tttaagcagcaagtagctgctgttcagcagtgtcagagcgccctccggctgccagaggag gtagtggccagtctgcctatctgccgcacagctcagactctgcagcaagaagccagccaa gtgcaacacaccacaatccagcagtgcaacatcctgcaggaggccgtggtgcagtatgag cagtatgaacaggaagtgaagaacctccagagattaattgaagaagctcatcggatcatt caggaccggcccgtttccactaataatatacaggaacttcaggctcagatacaccaccac gaggagttagcccagaagatccgtggctaccaggagcagatcgcctcgctccactccaag tgcaagatgctgacggtgaaggccaaacacgccactatgctgctgacggtcagcgaggtg gagggcttttcagacggcatggatgaactgagtgacgaggagcttcccagcgctgtgaca gacaccaccacagctgacgccaagcagcttccagcacacccctctgtagtcatgatgaca gccggccgctgccacacactcctctcccctgtgacagaggagtcaggggaggagggtacc aacagcgaggtctcctctccccctgcctgccgctccccctctccgggggctaacgctgaa gctgctcttaaccagggtcgaggtacactaagccgagtacctcttcaggaactgtacgac ccatctatggaaagcagtgctgctaacttggatgacctgcagagatcctgggaaacgcta aagaatgtgatcagtgagaaacagaagagcttatatgaggctctggagcggcagcaacac tatcaggagtccctccaatctatttccattaagatggagtccatcgagggggcgctgaat gagggcttagagcccaacaagactccagagagccagatggctgcacaccaggctttgatg gatgagatcctgatgctgcaggatgagattggtgagctacagatgtgcttctctgaggag ctggcagagagtgatggggatgctggggaacagctggccctgcagtctactctcactgta ctgggagaaaggatggccaccattcgaatgaaggcttcggggaaacggcagctgctggag gagaaactaagtgaacaactggaggagcagcgacaggagcaggcgctgcagcgataccac agcgaggccgaggagctcgacaattggctgctcagcactcgcgccactctcagctctgcc cttcagccccaaaatgaagacatggacatggaggagcagctcatcgactgtcagaatatg ctgtatgagatcgaacagaaggtgtcgtacctatcagagctatccgtccatagcgagagc ttgttgttggagggccgggctgaaaccaaaggcgaggcggagcagctcaccctgaaactg cgctccctcaaagacagcctgctagagctgcagcagatgctgcaggacaaacaagttgac atacagggttcactgcaagagcaggaggacagtgagccagattcgtctctgtcccagagt cctaacgttcaggactggctctctcaggcccggtcaacacgcacgcagcagcaacacgac aacctgcgtcgacagaaggagcttcaggagcacgtcgctgaacagaggaagctgctcaag tctgtagccagcgttggagaggagttactcggccaacaaaccacacccaatggggacagt gaggtgtctgtgcctggtggagtgctgctggagaatgagaccttgtctcctctggagcag ttgagacagagatgggaaaacctaaataatgatcagaacacaaagctgcagctctccttg aactccctggagcaagaccagcttagcccggtcctccaccggtcccgtctgtccagtccc agcgtggtgttcagaggtgaggctaccagccaggactcttgctctcctagagcttcgttt gaggcctgcagccagactttagaaagaatcacagaggaggcagcgggcagtgagagtaag cttgcagcatctttagggggggcaacaatccagcaggacctgtatgctgcagtatcagct gcctcgtcctggttagatgctgctgagaatcagctgctcgctggtcctgtgctgctctct gaggacacagagacacagctcacacatttggagggtttgaataaacagctgaaggagatg accagagaagtgaaaaattgcagagatctgctgggtggtggattggacaggctgtgtgga ggtgaagagcgagctctgatggaagacacgctagagggcctgcaggagaggatgggcctg ctggactctgcattggaacagcactgtgacgccatgagggacaggctgcaggaacattca gctttccagaatgaactgcggttgctgttcacagccctgactgaaagcaaacaccagttg ctacataagatggccggaactgcagacagacctgcatccaaacagatagagacattatca gaagtggaagacagcctgaaggaatttgagcagaaagttactgagctgaagacgaaagca gagggactccaatcagactcatcatccaatcaggagctactcaaactacaagatgcatac gaggagttggtgctcatggtgggctccagacggagtagtttgaaccatggtttgtctctg aaggctcagtatgaagctgcactgcacgaccttaatgacctggtggacaccgctcaggac aagatggctgctgaccaaaagatgacagtggcttcagtcatagaggttcagatgttacta gacaaacacaaagagtttttccagggtctggaatgccatatgatactcacccagacattt ttcagtaaagtgtctggtttggtgtctcagagggaaagtcaaaccctggaagagaccatg gctttagcccacagtgtgctcaaacaggcccatagaagaggagtggagctggaggggatt ctggagtcatggagcagactcgtggaggactatcaggctctgtgcagacagctggaggcg gtggagtgtagcatccccactgtgggtctggtagaggaaacggaagagaggctaaccgaa aggatcagcctctaccagcgacttaaagccagcctgactgagcaccagccccaactctat caggtactagaggagggcaagaagctttttctgtctgttggttgctcagacttggagaac cagctgacacagctgggagagcactggctctcctccaccactaaggtcaacaaggagctg caccgccttgattcgacactcaaacactggaccaggtaccagagtgagtcagcagagctg agccactggctgcagtcggccctggacagactggagttctggacgacccagtcggtgacc gttcctcaggagctggagactgtcagagaccacctctgtgccttcctggagttttccaaa gaggtggacgctaagtcgtctttgcgctcgtcagtgctgagcacaggtaaccagcttctg agactaaaaagggtggacacggctggcctgaggacagcgctgggccaagtcgacactcag tgggctgagctgctgactcgtatccctgtagtacaagagaagctccaccagctgcagatg gagaagttagcatcacggcatgccatcacagagctgatgagctggatctcgctcatggag aacatcatagaggaagatcaggacaagatcatggcagctgtgggctcagcggtggtacag gactacttgcagaagtataagggctttcgtatagatctgacgtgtaagcagctgactgtg gactttgtaaaccagtcagtgctgcagatcagcagtcaggatgtggagggaaagcgcagt gacaaaacggactttgctgagaagctaggagctatgaacagaagatggcagatactgcag gggctcattgcggaaaagattcagcttttagaaggacttgtggaaggttggttggagcat gaaaatggagttcaagcactgaaaacctggctcacagtacaggaggagaaattgaagaag agacagaggatagaggatgtagcatcggtgcagagtgcactcaaagactgtcaggagttg gaagaattagtgaaggaaaaagagaaggatctagagaaagcggaggaacgaggaaatgct ctcatccaggataagaaaggagcagcttgctgtgttgtaaaggaaactcttaaaggacta aaccagtcctgggctcatttggaccacatgataagtcagatgaaagtgagcctgcggttg gtgctggagcagtggacgttgtaccggcgagcttcagaggagataaatggctacctgatg gaggggcgttattctgtgtccaggctacgtctccttaatgggtctctggaggccgtgcag cagcaggtggagagtctagagagccttcaggaggagatggataaacaggaaagtagtttg aggaagtttggctccataactcaccagctgctaacggagtgccacccgtcggtggcggaa acgctcaacaaagctctccgggacgtcaacatcaggtggaatcttctgctagagcagatc tcagagcagctaaggaccagtaagtccttgctcggactgtggcagcgctacaggtcactg tacagccagtgcgtgactgcagtccacaaacaggaagaacgtgctgatcgacttctgagg agcgccactgacagggagataactgaagacgaaagcagtgcctggattaaggactgcaat gattgcctttgtgaccaagacgcggtgcagcagtccctccagcagctgcaagcactggga gaacaactgaggagccaagtcgactcctcctctgcggcatcccttcagtccgaccatttg tcgctcactcatcgcctagcagcactagagcacgccctgcacaggcaacaggatgtattg cagtgtggatctgtgacgtgtggggttttcagagagcagctagacaagctgatctgcatg gctgaggaggctgaggaagtgttgaaggattcggacccagtgggttcacccgaccttaat gtggtccagacgcgtatagaaaaactcaagggtcacctgttgaagctgagcagtctatct ccagacttggaacgtgttaatgagatggtgtacagaataccagtcagtgacagagacatt aaacggcttcaaagtctcaacagagcctgggccactcactctgctcacctcaccgagagg ttcagtaaactgcagtcggtgttgctccagcagcagagtttccttgagaagtgtgaggcc tggatggatttcctgactcagactgagaagaagctaggtgctgagatctcaggcaactac cagagtctgctggagcaacagagagaccatgagttgttccaggcagaaatgttcagcaga cagcagattctttactccatcataagtgacgggcatcgtttgttggaccaaggacaagtt gataagagttacgacttcagtgtaaaattggctttgctgagcaatcagtggcaaggtgtg gtgaggcgggcacaacagcggcgaggcatcatcgatagtctggttcggcagtggcagaac taccgggagatggcagagaagctgctccgatggctacaggaagtgacccgtgatccagat gtgcatcagccaggagaaccagtggctctgcagcaggccagaaacctgctagatcagata cagctgagggagcgagtgcttcagcggcagcaaggaggctacatcctcaccgtagaggcc ggcaggagtctgctgctgtcagcggacgccaaggcggagtccacactgcagactgagctg atggagattcaggagaggtggaggcatgcccaccatcgcctggaccagcagaggaggcag ctgcagggcttactgaagaactgggagcgatgtgagaagggcatagatgtgtctttggag aagctgagggccttcaagagaaagctgtctgtgcctctgcctgaccaccatgaggagctg cactcagagcaaatcagatgcaaggagctggagagcagcgtggagggctggaccgatgac cttacttccttattcctgctgagagactctttggagggcgtggtgagtgctgatgacatc acagttctacaagaacgcctccagctgctacagcgccagtgggaggaggtctgccaccag ctttccctgcgcaggcagcaggtgagcgagaagttgaatgagtgggctgtgttcaatgag aagaataaggaactgtgtgagtggctcacacagatggagagcaaagtctctcagaatggg gacatcagtatcgatgagatgattgaaaagctgcgcaaggactaccaggaggagatcagt gtcgctcaggagaacaagcagcagctgcaggttatgggtgagcgtctggccagggccagc caagacagcaaggcgacggaaatccagcacaaactcaacaaagtcagcgagcgctggcaa cacctgctggatctcattgcagccagggtgaagaagctgagggaaaccctggtggcggta cagcagttggataaaaacatgagcagccttcggtcatggctcgctcacattgagaccgag ctgtccaagcccatcgtctacaccacctgtgatgaccaggagattcagaggaagctcaac caacagcaggagctgcaaagggacatagagaaacacagcacaggcgtggcgtcggtgctg aacctgtgcgaagtcctgctgcacgactgcgatgcttgctcgactgagactgagtgcgac tccatccagcaggccaccagagggctggaccgacgctggaggaacatctgcgccatgtcc atggagaggaggctcaagattgaagaaacttggaggttgtggcagaagttcctggatgat tacagcaggtttgaggattggctcaagacctcagaaaaaacagcagccctgcctaattcc tctggagttctctataccgtcgctaaagaggagctcaagaagtttgaggctttccagcgt caggtgcaggagttcctgacccagctagagctcatcaacaagcagtatcgtcgtctggcc cgggaaaaccgcacagactcctcctgccgtctcagggaaatggtccacgatgggaacagg cgatgggacaacctgcagaagagggtggctgcagtcatacgcaggctaaagcacttcatc agccagagggaggagtttgagactgcacgtgacagcatcctggtgtggctgactgagatg gacctacagctcaccaacatagagcacttctccgagtgtgacgtacaggccaaaatcaaa cagctcagggcgtttcagcaggagatctacctgaacacggggaagatcgagctggtgttc aggcagggtgatgctctgattgagaagagtgaacctctggatgcagctgtcatcgaggag gagctggaggagctgcaaagatactgtcaggaggtcttcggacgagtggacagatactac aagaaactcacacgactccctcttgcagacgatgagctcgacggttcagacagagagctg gacatggaggatggaggagacctctctgaaatgcagtggagcgactcctctttgccccgg acatcagcgcgtccagcctcgggcactgtggctctcgtccgggccgaccgctcaggcaga gacaccccggccagcgtggactccatcccgttagagtgggaccacgactacgatctgagc agaggcctggagagcccctcaggacgaggcaatggggaaagaagccaagggcaagaggac gaggatgagtatatgaggacggctgccacagcactatcagatgtagttatcccagagagc ccagaggcctatataaaactgacagagaaaacactgaaatcatcctctggtgagccaggc cagctggaggccagtctcaggcagctggaccaggctttggacgcagggcggtatcacctc cagcagagagaagccactgccaaccgggtcagccccgatgtggactccacttacatgggc tacatgcgtctgatgggagagtgtcgcagcagcatagacgcagtgaagagagcagaagga gagctgaccgaagatgaggatgagatgccgggactcaccaaccctaccaacacagacaca cagagcgccggtgtgattgagcgctgggagctgatcgaggctcagtctctaagtgagaag cacaaacacaaacagaacctgcagcagtggcagcagctgatctcagatctgcagaccttg agggcttggctcggtcactcggaggctgaactcagccaactgcgaggcctcgatctcagc actgacatacacaccatccagcagagaatcaagaagctcaaggagctgcagaaggggatg gatgctcacaaggcagaggtcctgtccatcaacctgagcagtgctgacttcctccaatca gagcccgactctgaggaggcgtgggagctgagggacaggctgaaggagatgaattcgcgc tgggaccggctcggcgcctcactggaggactggagggaggagctgcagagggcactgatg cagtgccaggagttccatgagatgagtcacggtctgctgctatggttggagaacattgac cgcaggaggaacgaggtggttcccatcccccaaaaagcaaatcgcgaaacgttacgagct catcataaaacacttatgcaaatcaagtgcgagctgctggactcgcagcagaaggtgtcg tcccttcaggagctgtcagctcagctgctggtcaacattaaacctcagagtctggcccag acctcagagcggacccaggctcagggcaacgagtgtctggaggcccaggagaaggttcac gtgatctggaacaggctaaggctgctccagagggaggtcaactcagatctggaggggctg gagaggagactgggggccatggatgcagagcaggattgctcgccattgcctgttagcaga tctacagcacctggttcagatgtgaccagccagacccgcaaacgattgccccgaggcaaa agtagtcaggcccacccaggacaccctgagagcagcccgcgccacagccggagcagatca ccaggcgccgctggctgcgtttcctcccgttctgacctctcagacgtcacttcatcagct tcctcctcctcctcaaaggataagtccttcctgctgcgggtcctcagggcagcgctcccc gtccacttgctcctcctgctcctcatcggcctggcctgtctggttcccatgacggaggag gactacagctgccaccacgccaacaacttcgctcgctccttccatcccatgctgcgctac accaacggacctccacccatatga

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