Maylandia zebra (zebra mbuna): 101468300
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Entry
101468300 CDS
T02814
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
mze
Maylandia zebra (zebra mbuna)
Pathway
mze04217
Necroptosis
mze04620
Toll-like receptor signaling pathway
mze04621
NOD-like receptor signaling pathway
mze05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
mze00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101468300 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
101468300 (tyk2)
04621 NOD-like receptor signaling pathway
101468300 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
101468300 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mze01001
]
101468300 (tyk2)
Enzymes [BR:
mze01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101468300 (tyk2)
Protein kinases [BR:
mze01001
]
Non-receptor tyrosine kinases
JAK family [OT]
101468300 (tyk2)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
SH2_1
Kinase-like
Kdo
RIO1
ABC1
SH2
Tn7_TnsC_Int
Motif
Other DBs
NCBI-GeneID:
101468300
NCBI-ProteinID:
XP_004552201
UniProt:
A0A3P9CSX7
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All DBs
Position
LG4:19707746..19717013
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AA seq
1159 aa
AA seq
DB search
MGGRSRSSGSFSGLSEPPKDQGIHVYLFWTKDGKKYLSHTTGEVTAEQLCISAAETIGIT
ALCHSLFALYNPERHFWYSPNHIFKAEENPSLVLRYCMRYYFRNWHGLNENEPMMCRYPP
KSGSKRGFPLLDTTSLEYLFSQAKYEFVNEVVQMEYVKTEEEQTRFKNESLGMAVLHLSY
QAIKTESTLQDVASKVSFLDCVPRSFAKHISRDNFLTKLRIQRVFKDFVRSFQQHTVDRG
NLCTEEIMYKYIATLEHLAPRFGTETFPVTRLDLRDEDDRSGSCSSTTHAQCGSKDNFCG
PISHEISVSGTEGIQWRKVSAQRAQANNYMGNGYINYMRKPKQHSSQPDADTPNDWTFFS
EFPEITHIAITDSNVCISTRDNLCMEVQMISSQEAHSFVSLLDGYYRLTADAHHYLCHEV
APPRVVWSEANLLHGPMHDEFVLSKLKKEAEDEGTFLARWSVVDYNCIILAVLIKNQDGV
TRSHKQFRVHVKDSMLCLEGLERQFPSMKELTDSLKSFVLKSGSDSFTVKKCCSPKSGEL
SNLLVRRHNECDVHAEPLSQTYKTRLMFPQIKDKDIKQEQHLGRGTRTNIYSGRLLTQER
EESDNDEFNNNSHRGHRVVLKILDQTHEDIALLFFETASLMCQVSHRHLVFVYGVSVKGS
ENIMVEEFVDFGPLDVFLRREKNVSAGWKFIVAKQLASALDYLETNGLVHGNVCAKNILL
VKNGLEPNTTPFIKLSDPGIALSVLSREERLERIPWIAPECIDSGSNIGSHADQWSFGVT
MLEIYNNGDLPFNFNTLSEKERFYQQKGHLAEPSSPELARFINMCLTYEPEERPSFRKVH
RELIELMRKGFVIQSVMPSSEASANTDPTVFHKRYLKQVRILGEGHFGKVTLYLYDPAND
GKGEQVAVKSLKQENDKISDGWMKEIEILKSLYHSNIVKYKGCCTELGGQVVQLIMEYLP
LGSLKDYLPKRNLPLSHCLMFAQQICQGMNYLHSKRYVHRDLAARNVLVENDSLVKIGDF
GLTKYIPEGEIYYRVREDGDSPVFWYAIECLKESKFSFSSDVWSFGVTLYEILTRCDRRQ
SPPDKFFEMMKEAQGQMTVVILIKLLEQGLRLPCPKDSPHEVKILMERCWSADPSERPDF
ESLIKKFQSLRQAYWQSFS
NT seq
3480 nt
NT seq
+upstream
nt +downstream
nt
atgggagggaggtccagatcttcaggatcgttttcaggcctgagtgagcctccgaaggat
cagggcatccatgtctaccttttctggacaaaagatgggaagaaatatttgtctcacacc
acaggagaggtcacagcggagcagctgtgtatctctgcagcagagaccatcgggataacg
gctctgtgccattcactgtttgcgctgtacaacccagaaagacacttttggtacagccca
aaccacatatttaaggcagaggaaaacccgagccttgtacttcgctactgtatgaggtat
tactttcggaactggcatggactgaatgaaaacgagcccatgatgtgccgctatcctccc
aaatctggttcaaaacggggtttccctttacttgacacaacttcactggagtatttattt
tcccaggctaagtatgaatttgtgaatgaagtggtacaaatggaatacgtcaagacagag
gaggagcagactcgcttcaaaaatgagagtttgggaatggctgtgcttcacctctcatac
caggcaattaaaacggaatcaactttgcaagatgtagcttcaaaagtcagctttctagac
tgcgttccaagatctttcgccaaacacatttccagagacaacttcctgactaaactcagg
atccagcgagtgtttaaagactttgtgcggtccttccagcagcacacagtggatcggggc
aacctgtgcactgaggaaatcatgtacaagtacatcgctacactcgagcacttggcaccg
cgttttggcactgagactttccccgtaacccgcctggatctgagggacgaagatgaccga
agtggctcgtgttccagcaccacccacgcccagtgtggttcaaaagacaacttctgcggc
ccaatatcacatgaaatatcggtgtccggtactgaagggattcagtggaggaaggtgtct
gctcaaagggcacaggcaaataattacatggggaatggctacataaactacatgagaaaa
ccaaaacagcactccagccaaccagatgcagacacacccaatgactggaccttcttcagc
gagttccctgaaataactcacatagccattactgattctaatgtgtgcatcagcactcga
gacaatctctgtatggaggttcagatgatctccagccaggaggcccattccttcgtctcc
ctcctagatggatactaccgactgactgcagacgcccaccactatctttgtcatgaagtg
gctcccccaagggtagtgtggagtgaagcaaatctactgcatggacctatgcatgatgag
tttgtgctgtctaagctgaaaaaggaggcagaggatgagggaacattcctcgctcgttgg
agtgttgttgactataactgcatcatcctagctgttctaatcaagaatcaggatggtgta
acgcgaagccacaagcagtttcgtgttcacgtaaaggattcaatgctctgtctggagggc
ttggaacgacagttccccagcatgaaggagctcaccgatagcctcaagtcgtttgtcctc
aagtctggttcggacagctttactgtcaaaaaatgctgttcgccaaaatcaggagagcta
tccaaccttctggtgaggagacacaatgaatgcgatgttcacgccgagcccttatcccaa
acctacaagacccgtctaatgttcccccaaatcaaggacaaagatatcaaacaggagcag
catttgggtcgcggcaccagaactaacatctactcaggacggctgttaacgcaggaaaga
gaggaaagtgataatgacgagttcaacaacaactctcaccgaggccaccgagtcgttctt
aagattctggaccaaacccatgaagatattgctctgttgtttttcgaaaccgcaagtctc
atgtgccaggtatcccaccgtcacctggtgtttgtatatggcgtgtctgtcaaaggatct
gaaaacatcatggtggaggaatttgtggatttcgggcctttggatgtcttccttcgcaga
gaaaagaatgtgtctgctgggtggaaattcattgttgcaaaacagcttgccagtgccctc
gactatcttgaaaccaacgggttggttcatggaaatgtctgtgccaagaacatccttttg
gtgaaaaatggtctagaacctaacactactcctttcatcaagctgagtgacccaggaatt
gctctgagtgttctttcacgggaagagcgcctggaacgtatcccatggattgcccctgag
tgcattgacagtggttcaaacataggcagccatgctgaccagtggagctttggcgtaacg
atgcttgagatctacaacaacggtgatcttcccttcaacttcaacacattgtccgagaaa
gagcgcttttatcagcaaaagggccacttagctgaaccatcttccccagagttagccagg
ttcatcaacatgtgtttgacctatgagcctgaggagaggccgtcattccgcaaggtgcac
agagaactcatagaactcatgaggaaaggttttgtcattcagtctgttatgccttccagt
gaagcttcagctaacacagaccccactgtgttccataaacgctacctgaagcaagtgcgg
atcttaggagagggtcactttggaaaggtgactctgtacttgtatgacccagccaatgac
gggaagggagagcaggtggctgtgaagtctttgaagcaagaaaacgacaaaatttctgac
ggctggatgaaggagattgaaatcctgaaatctctttatcacagcaacattgtgaaatac
aagggctgttgcacagaactgggagggcaagtcgtccaactaataatggagtaccttcct
ctggggagtctgaaagactacctccccaaacgtaaccttccgctgtctcattgtctcatg
tttgctcagcagatctgtcaggggatgaattacttgcactcaaagcgatacgtccatcgc
gatctggctgcccgtaatgtcttggtggaaaatgacagtctggtaaagattggagacttt
ggcctgacgaagtacatccctgagggtgagatctactaccgtgtccgtgaggatggagac
agtccagtgttctggtatgccatcgagtgcttgaaagagagtaaattttccttctcctct
gatgtttggtcctttggagttacactgtatgagatcctgacccgctgtgaccgtcgccaa
agccctccagataagttctttgaaatgatgaaggaagctcaaggacagatgactgtggtg
atactgataaaactgttggaacaagggttgcgattgccttgccctaaggacagcccacat
gaggtgaagatattaatggagcggtgttggagtgcagatccttcagaacggccagatttt
gagtccctaattaaaaagtttcagagcctacgccaagcatactggcagtccttttcatag
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