Maylandia zebra (zebra mbuna): 101474114
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Entry
101474114 CDS
T02814
Symbol
zgc:158659
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
mze
Maylandia zebra (zebra mbuna)
Pathway
mze00562
Inositol phosphate metabolism
mze01100
Metabolic pathways
mze04012
ErbB signaling pathway
mze04068
FoxO signaling pathway
mze04070
Phosphatidylinositol signaling system
mze04081
Hormone signaling
mze04140
Autophagy - animal
mze04145
Phagocytosis
mze04150
mTOR signaling pathway
mze04210
Apoptosis
mze04218
Cellular senescence
mze04370
VEGF signaling pathway
mze04510
Focal adhesion
mze04517
IgSF CAM signaling
mze04518
Integrin signaling
mze04620
Toll-like receptor signaling pathway
mze04625
C-type lectin receptor signaling pathway
mze04810
Regulation of actin cytoskeleton
mze04910
Insulin signaling pathway
mze04914
Progesterone-mediated oocyte maturation
mze05100
Bacterial invasion of epithelial cells
mze05132
Salmonella infection
mze05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
mze00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
101474114 (zgc:158659)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101474114 (zgc:158659)
04370 VEGF signaling pathway
101474114 (zgc:158659)
04068 FoxO signaling pathway
101474114 (zgc:158659)
04070 Phosphatidylinositol signaling system
101474114 (zgc:158659)
04150 mTOR signaling pathway
101474114 (zgc:158659)
09133 Signaling molecules and interaction
04081 Hormone signaling
101474114 (zgc:158659)
04517 IgSF CAM signaling
101474114 (zgc:158659)
04518 Integrin signaling
101474114 (zgc:158659)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagocytosis
101474114 (zgc:158659)
04140 Autophagy - animal
101474114 (zgc:158659)
09143 Cell growth and death
04210 Apoptosis
101474114 (zgc:158659)
04218 Cellular senescence
101474114 (zgc:158659)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101474114 (zgc:158659)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101474114 (zgc:158659)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
101474114 (zgc:158659)
04625 C-type lectin receptor signaling pathway
101474114 (zgc:158659)
09152 Endocrine system
04910 Insulin signaling pathway
101474114 (zgc:158659)
04914 Progesterone-mediated oocyte maturation
101474114 (zgc:158659)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
101474114 (zgc:158659)
09171 Infectious disease: bacterial
05132 Salmonella infection
101474114 (zgc:158659)
05100 Bacterial invasion of epithelial cells
101474114 (zgc:158659)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mze04131
]
101474114 (zgc:158659)
Enzymes [BR:
mze01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
101474114 (zgc:158659)
Membrane trafficking [BR:
mze04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
101474114 (zgc:158659)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_C2
PI3K_p85B
PI3K_rbd
ABC1
DUF2321
Motif
Other DBs
NCBI-GeneID:
101474114
NCBI-ProteinID:
XP_014268487
LinkDB
All DBs
Position
LG3:complement(9097583..9116096)
Genome browser
AA seq
1070 aa
AA seq
DB search
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVCGKVALSLWPVPHGLEDLLNPIGAAGSNPNKETPCVELEFS
WFNQIVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSSGDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLMLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
NT seq
3213 nt
NT seq
+upstream
nt +downstream
nt
atggtgcccaggccatcgtcaggggaactatgggggctccacctgatgcccccccggatc
ctggtggactgctgcctgcctaacggtatgatggttagcctggagtgtctgagggaaact
cctctcatcagtatcaagcagcagctcttctccgaggccaggaagtaccccctgtaccac
ctgctgcaggaggagtcgtgctacatctttgtgggcgtgacccaggaggctgagagggag
gagttttacgatgagacgaggcggctgtgcgacctgcgcctgttccaccccatccttaag
gtcatcgagcccctcggcaaccgtgaggagaaaatcctgaaccgtgagatcggtttcgcc
atcgggatgccggtctgcgagtttgagatgatgaaggacccggaggtccaggacttccgc
cgttccatactgagcgtgtgcagagaggccatggaggaacgggaaggagggggggcccac
agccaggcgctctacgtttacccccccaacgtggagtccagtccccagctgccccagcac
atctatagcaagctggacaaagggcgcctgattgtgaccatctgggtgatcgtgtctcca
tcaaactccaaacagaagtacaccttgaaggttagtcacgacagtttacctgagcagctg
atcgccgagtccatcaggaagaaaagccgatcgatgcacctttcacctcagcagctccgc
ctctgcgttcaggagtaccagggccagtacatccttaaggtgtgtggctgcgatgagtac
ctgctggagaagtttcctctcagtcagtataagtacatccgctcctgcatcatcgtggga
cgtcttcctcacctgatgctcgtgtccaaagacagcctctactctcagcttcccgcctca
ggcttcgtcacgccttcctacagccgtcggactcctcagccgtctccctgtccaggagga
ggcgacggttctcctcctcgctccttgtgggccttcaacactctgctgagagtccggctg
ctctgcgccacgtacgtgaacgtgaacatcagagacatcgataagatctatgtgaggaca
gggatctatcacggaggagagccgctctgtgacaacgtcaacacccagagagtgccctgc
tccaaccccaggtggaatgagtggctgacctatgacatctacctggctgacctccctcgt
tcagccagactctgcctgtctatctgctctgtgaagggaaggaaaggagctaaggaggag
cactgccctctggcctgggggaatgtaaacctgtttgactacaaggacatcctggtctgt
ggtaaggtggctctcagcctgtggcctgttccccatggcctagaggacctgctcaacccc
attggagccgcgggttcaaatcccaacaaggagaccccctgcgtggagctggagttctcc
tggttcaatcagatcgttgtttttcctgacgagcagcagattgaagagcacgccaactgg
accatcagcagagagctgggctacaactactgccacggcctgagcagccgtttggcctgt
gacagcagtgtttcgtcaggcgatgccgagcagcttcgctctctctgctccagagatccg
ctgtacgagctctcggagcaggagaaggacttcctctggagacacagacattactgtgta
aacatcccagagtctctccctaagctgcttctttctgtcaaatggaactccagagacgaa
gtttctcagatgtactgtctgttgaaggagtggcctctgatggagcccgagtcggctctc
gagttgttggactgtaactttcccgacccaatggtccgagagtttgcgctgcgctgcctc
gtgcagggcctgacggatgacaagctgtcgcagtacctgttgcaacttgtacaggtgttg
aagtatgagatgtacctggacaatcctctggcccgtttcctgataaagaaagctctgacc
aatcagaggatagggcacttcttcttctggcacctgaagtcagagatgcacaacaagacg
gtttcccgacgcttcggtctgctgctggaagctttctgcagagcctgcgggatgtacctg
aagcacctgaacagacaggtagaggccatggataaactggtgaatctgaccgacacactg
aagcaggagaagaaggacgagactcagaaaactcagatgaagtttctggttgagcacatg
tctcgtccagattacatggaagctctgcagggattcgtctctccactgaatccagttcac
cagctgggaaatctcaggctggaggagtgtaggatcatgtcctcggcaaagcgccccctg
tggctgaactgggaaaaccctgacatcatgtccgagcttctcttcaccaacaacgagatc
atcttcaagaacggagatgacctgcgtcaggatatgctaacgttgcagattattaaaatc
atggagaacatctggcagaaccagggtctggacctgcgcatgttgccctatggatgcctc
tccatcggtgactgcgtgggtctgatcgaggttgtgaagaacagcttcaccatcatgcag
attcagtgcaagggaggcctgaagggggcgctgcagttcaactccaacacgctgcatcac
tggatcaaagacaagaaccgcggcgaagcgtacgatcgggccatcgacctgttcacgcgc
tcatgtgctggttactgcgttgccacgttcatcctgggaatcggagaccgccacaactcc
aacattatggtgaaagagaatggacagctgttccacattgactttggtcacttcctggat
cacaagaagaagaaatttggctacaagagggagcgtgtaccctttgtccttactcaggac
ttcctcatcgtcattagtaaaggcatccaggaatccaccaagaccaaggagttcgagagg
ttccaggagatgtgctacaaagcatacctcgccatccgtcagcacgccagcctcttcatc
aatctcttctcccttatgctgggttgcgggatgcctgaactgcagagctttgatgacatt
gcctacctgaggaaaaccctggccctggagaagagccagcaggaggcactggagtacttc
accaagcagatgaacgacgctcaccacggcggctggagcacgaagatggactggatcttt
cacaccataagacacatgcccaatgagcactga
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