KEGG   Maylandia zebra (zebra mbuna): 101478273
Entry
101478273         CDS       T02814                                 
Symbol
rock1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
  KO
K04514  Rho-associated protein kinase 1 [EC:2.7.11.39]
Organism
mze  Maylandia zebra (zebra mbuna)
Pathway
mze04270  Vascular smooth muscle contraction
mze04350  TGF-beta signaling pathway
mze04510  Focal adhesion
mze04520  Adherens junction
mze04530  Tight junction
mze04810  Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:mze00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    101478273 (rock1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101478273 (rock1)
   04520 Adherens junction
    101478273 (rock1)
   04530 Tight junction
    101478273 (rock1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101478273 (rock1)
 09150 Organismal Systems
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    101478273 (rock1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mze01001]
    101478273 (rock1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mze03036]
    101478273 (rock1)
Enzymes [BR:mze01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.39  ROCK-subfamily protein kinase
     101478273 (rock1)
Protein kinases [BR:mze01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   101478273 (rock1)
Chromosome and associated proteins [BR:mze03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    101478273 (rock1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Rho_Binding PH C1_1 Pkinase_C Filament APH PRANC
Other DBs
NCBI-GeneID: 101478273
NCBI-ProteinID: XP_004542908
LinkDB
Position
LG18:10854719..10886059
AA seq 1386 aa
MSFAAKMSAGDTMEARFEKIDAMLKDPKSEINTDCLLDGLDALVYDLDFPALRKNKSIDN
FLNRYKETISNIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKATSKVYAMKLLSKFEMIK
RSDSAFFWEERDIMAFANSSWVVQLFFAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKW
ARFYTAEVVLALDGIHSMGFIHRDVKPDNMLLDKAGHLKLADFGTCMKMNKDGMVRCDTA
VGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHK
NALTFPDDSDISNDAKNLICAFLTDRDVRLGRNGVDEIKRHPFFKNDQWTWENIRETAAP
VVPELSSDTDTSNFDDIEEDRGEEETFPIPKAFVGNQLPFVGFTYYSNQHLLRRSADTKS
SDKRSSSTKEDKSHLENLQKRIYQLEEQLHSEMQLKDELEQKCRTSNNKIEKIMKELDEE
ANLRKSADASLSLLEKDKLMQQHRFTEYQRKADQESEKRRNLENEVSNLKEQLEDMKKIS
QNSQASNDKITQLQNQLEEANDLLRAESDTAGRLRKSHTEMTKSMAHLENLNRELQERSR
AVEGEKAQLEKELLLLQSTLDSERRNYSQDSEEIRELQARLSGLQEDNKNLKLSLSKMEA
ERKQAQERSNNLEKEKNNLEIDLNYKLKTLQQRLEQEQTEHRVTRAQLTDKYESIEEAKS
AAMSAVQQKMSEETGARMRAESRVVEVEKQCSMLEFDLKQSVQKMEQLMKQKERLEDEVK
NLQIQVEQESSKRIQIQNDLKTRMQEMDRLRCSEKQLKQEINTSLESKRSLEFQLAQLSK
QYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEERNRQIQEANKKVQDLCNERDS
LSAQLDLTVTKAESEQLARALQEEQYFELSQENKKAVTRHKQEIGEREATIARLEESYKT
LTKDVENLSREKTELSEKLRIQDEEYVAQKEEIEKSIKANYEKILYTERTLKTQAVNKLA
EIMNRKDMKLDQKKKGSTADLRKKEKENRKLQLELNQEKEKFNHMAIKYQKELSEMQAQL
AEESTYRNELQMQLDSKESDIEQLREKLNDLQQRMDNSSVTSLQTDETDSNIAESRLEGW
LSIPNRANIKRYGWKKQYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDV
YRAETDEIPRIFQILYANEGECRKEADLETVPQGDKTNCLPHKGHEFIPTLYHFPSNCEA
CAKPLWHVFKPPPALECRRCHVKCHKDHLDKKEDVIAPCKVNYDVTSARDMLLLALTQDE
QKKWIGHLGKKIPKTPPSTFTRASPRSMSTRSGPNQSFRKNPKSNTGKLSRAQSTLQAAD
TTSSTC
NT seq 4161 nt   +upstreamnt  +downstreamnt
atgagttttgcagcaaaaatgtctgctggggatacgatggaggctcgatttgaaaagatc
gatgccatgttgaaagacccaaagtcagaaataaacacggattgtctgctggatggcttg
gatgcactggtatatgaccttgacttccctgccctgaggaaaaacaagagtattgacaac
tttttgaatagatacaaagagacgattagtaacattcgtgatctgcgaatgaaagcggag
gactatgaggtggttaaagttattgggaggggtgcatttggagaggtgcagttggtaaga
cataaagcgacaagcaaagtatatgccatgaagctgctgagtaagtttgagatgatcaag
aggtcagactctgctttcttctgggaggagagggacatcatggcctttgccaatagttca
tgggtcgttcagctcttttttgcattccaagatgaccgctacctctacatggtgatggag
tacatgcctggtggtgatttggtaaacttgatgagcaactatgacgtcccagagaagtgg
gctcgcttttacacagccgaggtagtcctggccctggatggaatccactctatgggcttc
attcacagagatgtcaagcctgataacatgttgcttgacaaagcaggccacttaaagctc
gcagactttgggacctgcatgaaaatgaacaaggacggtatggtacgatgtgacacagca
gtgggaactccagactacatttcacctgaggtactgaaatcccaaggaggagatggctat
tatggcagagagtgcgactggtggtcagtgggagtgtttctgtatgaaatgttagttggc
gacactcctttctatgcagactcactagtggggacctatagcaaaattatgaaccacaag
aatgcgctgaccttccctgatgacagcgacatatccaatgacgccaagaatctgatctgt
gctttcctgaccgacagggatgttcgactcggccgtaatggtgtagatgaaatcaagagg
catcccttcttcaagaatgaccagtggacgtgggagaacatcagagagacggctgcccct
gtagtccccgaacttagcagtgacactgacaccagtaactttgatgacattgaggaggat
cggggagaggaggagacctttcccataccaaaggcctttgtgggcaaccagctcccgttt
gtaggcttcacctattacagtaatcaacaccttttgcgaaggtccgctgacacgaagagc
agtgacaagcgtagcagttccacaaaagaagataagagtcatttggagaacctgcaaaaa
cgaatctaccagctagaggagcagctgcacagtgaaatgcagttgaaagatgagttggag
cagaaatgcaggacatcaaacaacaagattgaaaagattatgaaagagctggatgaagag
gcaaacctgaggaagagcgccgatgccagcttgtctctgctggagaaggacaagcttatg
cagcagcacagattcacagagtaccaaagaaaagccgaccaggagtcagagaagagacgg
aatttggaaaacgaagtgtcaaatttgaaggagcagttggaagatatgaagaaaatcagt
cagaactcgcaagcctcaaatgacaagattacccagcttcagaatcagctggaagaggcc
aacgacttgctgcgtgcagagtcagacacggcggggagactgaggaagagccacacagag
atgaccaagtcaatggcacatttggagaatttgaaccgtgagctgcaggagaggagccgc
gcagtagaaggagagaaggcgcagctggagaaagagctcctgcttctacagagcaccctg
gactctgaacggaggaactacagtcaggactcagaggagatcagggagctgcaagcgaga
ttgtcggggttgcaagaggataacaaaaacttgaagcttagtctgtccaagatggaggcg
gaacgcaaacaggcccaggaaagaagcaataatttggagaaggaaaagaacaatttggag
atagacctgaattacaaactgaagaccttgcagcagcgtctggagcaagaacagacggag
cacagggtgacgcgggcacagctcactgacaaatacgagtctatcgaagaagccaaatca
gctgccatgtctgctgtccagcagaagatgtcagaggagacgggagcaaggatgagggca
gagagccgggtggtggaggttgagaagcagtgctcaatgttggagtttgaccttaagcag
tctgtgcagaaaatggagcagctgatgaagcaaaaggaacggctggaggatgaggtgaag
aatctgcagattcaggtagagcaggagtcaagcaaacgcatccagattcagaacgacctg
aagacccgcatgcaggagatggaccgtcttaggtgttcagagaaacagctcaaacaagag
atcaacacatcactggaaagtaaacgctcactggagtttcagctggcacagctgtccaaa
cagtacagaggcaacgagggacagatgagggaacttcaggaccagcttgaggctgaacag
tatttttctacgctttacaaaactcaggtcaaagaactaaaagaggagattgaggaaagg
aaccggcagatacaggaggctaataagaaggtgcaggatttgtgcaacgaaagggattcc
ttgtctgcacagctggatctgacagtgaccaaggccgagtcagaacagcttgctcgggca
cttcaggaggagcagtatttcgagctcagccaagagaacaagaaagcagtgacaaggcat
aagcaggagattggggagagagaggctactattgcacggcttgaggaatcctataaaact
ctgaccaaagatgtggagaatctcagcagagagaagacggagttaagtgaaaagcttcgt
attcaggatgaagaatatgtcgctcagaaggaagaaattgaaaaatcaatcaaggccaac
tacgagaagatcctctacacagagcgcacactgaagactcaggcggtgaacaaactggca
gagatcatgaatcgtaaagacatgaagctggaccagaagaagaagggtagcacagctgat
ctgcggaaaaaggagaaggaaaaccgcaagcttcagctggagcttaatcaggagaaggaa
aagtttaaccacatggccatcaaataccagaaggagctgagcgagatgcaggcgcaattg
gcagaggaaagcacgtatcgcaacgagttgcagatgcagctggacagcaaggagagcgac
atcgagcagctccgggagaaactgaacgacctgcagcagcgcatggataactccagcgtc
accagcctgcagacagacgagacggacagtaatatcgcagagtccagattggagggttgg
ctgtctattcctaatcgtgctaacatcaaaagatacggatggaagaagcagtatgtggtg
gtgagtagtaagaagattctgttctacaatgacgagcaggataaggagcagtccaacccc
tcgatggtactggatatcgacaaactgtttcatgtgaggccagtcacgcaaggagatgtg
taccgagctgagactgatgagattccaaggattttccagattttgtatgctaatgaggga
gagtgcaggaaggaggcggatctagagacagtccctcagggcgacaagaccaactgtctc
ccacacaaaggccacgagttcatccccacgttatatcacttcccttcaaactgcgaggcc
tgtgccaagcctctgtggcacgtcttcaagccgcctccggccctggagtgtcgccgctgc
cacgtgaagtgccacaaggaccaccttgacaaaaaggaggatgttattgctccttgcaaa
gtaaactacgacgtgacctctgcccgggacatgctgctgctggctctgacccaagacgag
cagaagaaatggatcggccacctcggaaagaagattcccaagaccccgccgtcgacattc
acaagagcctcgccgcggtccatgtccactcgctctggacccaaccaatccttccgcaag
aaccctaaaagcaatacaggaaagctgagcagagcgcagtccaccctccaagcagcagac
acaacatcgagcacttgttga

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