Nisaea acidiphila: NUH88_11450
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Entry
NUH88_11450 CDS
T08369
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
naci
Nisaea acidiphila
Pathway
naci00290
Valine, leucine and isoleucine biosynthesis
naci00660
C5-Branched dibasic acid metabolism
naci01100
Metabolic pathways
naci01110
Biosynthesis of secondary metabolites
naci01210
2-Oxocarboxylic acid metabolism
naci01230
Biosynthesis of amino acids
Module
naci_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
naci00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
NUH88_11450 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NUH88_11450 (leuC)
Enzymes [BR:
naci01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
NUH88_11450 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
NUH88_11450 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
UUX48034
UniProt:
A0A9J7AM48
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Position
2486388..2487797
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AA seq
469 aa
AA seq
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MSKPRTLFDKIWQDHLVDVQDDGTCLIYIDRHLVHEVTSPQAFEGLRNAGRKVRRPEFTL
AVADHNVPTKDLDKGIADEDSRIQVATLEQNVSDFGVPYFDMKDNRRGIVHIIGPEQGFT
LPGTTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLVQKPAKNMRITVKGELPKGV
NSKDIVLAIIGKIGTAGGTGHVIEFAGEAVRGLSMEARMTICNMSIEAGARAGLIAPDET
TFEYLKGRPFAPKAGAWEQAVAYWKTLPSDEGAVYDTEVELNAADIVPQVTWGTNPEEVV
PITANIPDPEQMSDPVRKAKIARSLEYMGLTAGTPINEVKIDKIFIGSCTNGRLEDLRIA
AGVLKGRKLADGVQAIIVPGSGLVKEKAEEEGLDKVFIEAGCEWREPGCSMCLAMNADRL
EPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVAGHLTDVRDLLN
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atgtcaaagccgcgtacgctgttcgataagatctggcaggaccatctggttgacgttcag
gacgacggaacgtgccttatctatatcgaccgccacctggtgcacgaagtcaccagcccg
caggccttcgagggactccggaatgccggccgcaaggtgcgccgcccggaattcacgctc
gcagtcgccgatcacaacgtgccgacgaaggatctcgacaaggggatcgccgacgaggac
tcccggatccaggtcgcgacgcttgagcagaatgtctccgatttcggcgtgccctatttc
gatatgaaggacaaccggcgcggcatcgtgcacatcatcggtccggagcagggtttcacc
ctgccgggcacgacgatcgtctgcggcgacagccacacctcgacccacggcgccttcggc
gcactcgccttcggcatcggcacctcggaggtcgagcatgtgctcgccacccagaccctg
gtgcagaagccggccaagaacatgcggatcacggtcaagggagagctgcccaagggcgtg
aactccaaggatatcgtgctcgccatcatcggtaagatcggcacggccggcggcaccggc
catgtgatcgagttcgcgggcgaggccgtccgcgggctttccatggaagcgcggatgacg
atctgcaacatgtcgatcgaggcgggcgcccgcgccggcctgattgcgccggacgaaact
accttcgaatatctgaagggtcgtcccttcgccccgaaggccggtgcctgggagcaggcc
gtcgcctactggaagacgctgccgtccgacgaaggcgcggtctacgacaccgaggtcgaa
ctgaacgcggccgatatcgtgccgcaggtgacctggggcacgaacccggaagaggtcgtt
ccgatcaccgcgaacattccggatccggaacagatgtccgatccggtccgcaaggcgaag
atcgcccgctcgctcgaatatatgggcctcaccgccggcacgccgatcaacgaggtcaag
atcgacaagatcttcatcggctcctgcaccaacgggcgcctcgaggacctgcggatcgcc
gccggcgttctcaagggccgcaaactggccgacggggtacaggcaatcatcgtcccgggc
tccggcctggtgaaggagaaggccgaggaagaaggtctggacaaggtcttcatcgaggcc
ggctgcgaatggcgcgagccgggctgctccatgtgcttggcgatgaatgcagaccggctg
gagccgggcgagcgttgcgcctcgacctcgaaccggaacttcgaaggccggcagggtcgc
ggcgggcgaacccatctggtgagcccggcaatggcggcagcggccgccgtggccggtcac
ctgaccgatgtccgcgatctgctgaactaa
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