Necator americanus (New World hookworm): NECAME_01399
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Entry
NECAME_01399 CDS
T04867
Name
(RefSeq) 3'5'-cyclic nucleotide phosphodiesterase
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
nai
Necator americanus (New World hookworm)
Pathway
nai00230
Purine metabolism
nai01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
nai00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NECAME_01399
Enzymes [BR:
nai01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
NECAME_01399
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
NECAME_01399
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
HD-CE
Motif
Other DBs
NCBI-GeneID:
25341441
NCBI-ProteinID:
XP_013307737
UniProt:
W2TTV3
LinkDB
All DBs
Position
Unknown
AA seq
716 aa
AA seq
DB search
MARISANRIVYLICITLQDVFRFQSEDLESRRRIILDHGDDQVRILYELAQCCAQIANTD
LCELFVQNEEGVFLVYKEMGEKPQIKCRKVKRARRNPMHLQKLIDIDEGNIGEIHFNTPV
SERDRQIINVICTWAAASLHYAQVAAQLERTGSSSEIFARQRRLNQFLLDVAKSIFQDIV
SMDTVIIKVMNFAAKLVDADRASLFLVDNKNHELYARIFDIGRGSEELEKINKEGHKEIR
FSMNRGIAGHVASTGEGLNIEDAYEDSRFNPEVDSKTGYTTKTILCMPIFIRGSVIGVVQ
MVNKHEGVFTKADEDSFEVFAVYCGLALHHAKLYDKIRRSEQKYRVALEVLAYHSVCNKD
EVAKLQKMEIRDRVEELETFEFNYLRMSELEKPLYAIAMFKTLFQEQFRYDRDDLIRFVL
TVRKNYRRVAYHNWAHGWSVAHAMFVLLMHTSRDIFNTHEALALYVSCLCHDLDHRGKNN
AYMKSMMTPLASIYTTSVMEHHHFNQTVTILQQDGHNILKTMNSSDYKQALSLIKHCILA
TDLALFFTNKAELNKILDSGKYDIHDEHHRRLTQAILMTGCDLIASAKPWYIQTETVKVI
FEEFYEQGDAERQNGREPIAMMDRNKAHELPQMQVTLLSFLLLAQYSNFLSTILMVGFMR
GICLPCYELVAKVIPDAAFLRDQCEYNAKKWEELAAEQAELNKQKTEETTIEKGKE
NT seq
2151 nt
NT seq
+upstream
nt +downstream
nt
atggcaaggataagcgcgaatagaatagtatatctaatatgtataactctacaagatgtt
ttccgttttcagtcagaagatctcgagtccagacgccgtattatcctggaccacggagac
gatcaggtccggattctatatgaattggcgcaatgttgtgctcaaatcgccaacaccgac
ctctgcgaattatttgtccagaacgaggagggcgtttttcttgtctacaaggaaatgggc
gagaagccacaaattaaatgtcgtaaagtgaaacgcgctcgtagaaatcctatgcatcta
cagaagttgatcgatatcgacgaaggaaatattggagaaatccacttcaatacgcctgtc
tcagaacgggaccgacaaatcatcaatgtgatttgtacgtgggctgcagcttcactgcac
tatgcgcaggtagctgctcaacttgagcgaacaggtagcagctcggaaatatttgctcga
caacgacgtcttaaccagtttctccttgacgtcgcgaaaagtatcttccaggatatcgtc
tccatggacacggtgataatcaaggttatgaacttcgctgcaaaactggtcgatgcggac
agagcatcgttgtttcttgttgacaacaaaaatcatgagctctacgccagaatattcgac
attggtagaggaagcgaggaactggagaagattaacaaggaaggacataaggaaattcgg
ttcagcatgaatcgaggaatagcagggcacgtggcttcaactggcgagggactcaatata
gaggatgcctacgaggatagcaggtttaatcctgaagtggactcaaagactggatacact
acaaaaactattctttgtatgccgatattcattcgtggcagtgtaattggcgtcgtgcaa
atggtgaacaaacacgagggtgtattcacgaaagccgacgaggacagttttgaggtgttc
gctgtatattgcggattagcactgcaccacgctaaactctacgataaaatcagaagatct
gaacaaaaatatcgcgtcgctttggaagttctcgcttatcatagcgtgtgtaataaagat
gaggtggctaagctacaaaagatggagatcagagaccgagtggaagagcttgagacgttt
gaattcaactatttgcgtatgtcggagctggagaagccactgtacgcaatcgctatgttc
aaaacattattccaggagcaattccgttatgatcgcgacgacttgattcgttttgttctc
actgtgaggaagaactatcgacgagtggcgtatcataactgggcgcatggatggtccgta
gctcatgccatgtttgttttgttaatgcatacatctcgtgacatcttcaacactcacgag
gcactagcgctgtatgtgtcgtgtctgtgtcatgacttggatcatcgtggaaaaaacaac
gcctacatgaaatcaatgatgacaccgttggctagtatttatacgacatctgtaatggag
catcatcacttcaatcaaacggtgaccatccttcaacaagatggtcataatatcctgaaa
acaatgaactcatccgactataaacaagcgttgtccctcatcaagcactgcatcctcgcc
acggatctcgcgctattcttcactaacaaagcagaacttaacaaaatcctcgacagcggc
aaatacgatatccatgacgagcatcaccggagactgactcaagcgattttaatgaccggt
tgtgacctgatcgcttccgctaagccatggtacattcagacggagaccgtgaaggtcata
ttcgaggagttctacgagcagggtgacgctgaacgacagaacggacgtgaaccgatcgca
atgatggatcgtaacaaggcacatgaacttccccagatgcaggttacgcttctgtcattt
ttgttgcttgcgcagtactcgaatttccttagcaccattttaatggtaggatttatgcgt
ggtatttgtctgccatgttatgaactagtcgctaaagtgattccggatgcagcgtttctg
agggatcagtgcgagtacaacgctaaaaaatgggaggagttggcagccgaacaagcggaa
ttaaacaaacaaaaaactgaagagacaacaatcgagaaaggaaaggagtga
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