Necator americanus (New World hookworm): NECAME_06519
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Entry
NECAME_06519 CDS
T04867
Name
(RefSeq) methylmalonate-semialdehyde dehydrogenase
KO
K00140
malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:
1.2.1.18
1.2.1.27
]
Organism
nai
Necator americanus (New World hookworm)
Pathway
nai00280
Valine, leucine and isoleucine degradation
nai00410
beta-Alanine metabolism
nai00562
Inositol phosphate metabolism
nai00640
Propanoate metabolism
nai01100
Metabolic pathways
nai01200
Carbon metabolism
Brite
KEGG Orthology (KO) [BR:
nai00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
NECAME_06519
00562 Inositol phosphate metabolism
NECAME_06519
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
NECAME_06519
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
NECAME_06519
Enzymes [BR:
nai01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
NECAME_06519
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
NECAME_06519
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Motif
Pfam:
Aldedh
LuxC
YCII
DUF5421
Motif
Other DBs
NCBI-GeneID:
25346551
NCBI-ProteinID:
XP_013307451
UniProt:
W2TUB1
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All DBs
Position
Unknown
AA seq
455 aa
AA seq
DB search
MEAATESCKKAFASWKNTSPLTRQQTLFRLQSLIKRDIKKIAENITLEQGKTLPDAEGDV
NRGLQVVEHACSVPSLMLGETLPNVSRDMDTYSFRIPLGVTAGICPFNFPAMIPLWMFPL
AIATGNTMLLKPSEQDPGACMMLVELAKEAGIPDGCVNVIHGQHDAVNFICDHPAIRAIS
FVGADTAGKHIYERGAQNGKRVQSNMGAKNHGVIMADCNKEQTLNQLTAAAFGAAGQRCM
ALTTAILVGEARAWLPEIVEKAKKLHVNAGWKPDTDVGPLISKAAKNRVISLIQGAKKEG
ANVALDGSDIVVPGFENGNFVGPSVIAGVKPNMTCYKEEIFGPVLVIMEAENLNEATEII
NQNPYGNGTAIFTSNGATARKFTNEVDVGQVGVNVPIPVPLPMFSFTGSRGSFLGDMNFY
GKAGINFYSQWKTVTQYWNESLTELKPQMSFPQLK
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atggaagcagctactgaatcgtgtaagaaagcttttgcttcgtggaagaatacatcacca
ttgactcgtcagcaaacgcttttccgccttcaaagcttaattaaacgcgacataaagaaa
attgctgaaaacatcactctagagcagggaaagactttgcccgacgccgaaggagatgtc
aatcgaggtcttcaggttgtggaacatgcctgctccgtcccatcgttgatgcttggagaa
acgcttccgaatgtttcgcgggatatggatacctattcttttcgcatccctctaggagtg
acagctggcatttgtcctttcaacttccctgctatgattccactgtggatgttcccgtta
gccattgctaccggcaatactatgcttctcaaaccctcagaacaagatcctggggcgtgc
atgatgcttgttgagctagccaaggaggctggaatacctgatggttgcgttaacgttatt
cacggacaacatgatgcagtaaatttcatatgcgatcatcctgctattcgtgccatatct
ttcgttggggctgacacagctggaaaacacatttacgaaagaggtgctcaaaacggaaag
cgtgtgcagtctaatatgggagcgaaaaatcatggagttataatggcggactgcaataag
gagcagaccctcaatcaattaaccgctgctgcatttggagccgctggtcagcgttgtatg
gctctaaccactgcgatactcgttggagaagcccgcgcctggcttccagaaattgtggaa
aaggccaagaaactgcatgtgaacgcaggatggaagccagacacagacgttggtccgctg
atctcaaaagcagccaaaaatcgcgtaatcagtcttatccaaggagccaaaaaggaagga
gctaatgtcgctctagatggaagcgacattgtcgtacccggattcgaaaatggtaacttc
gttggtccgtctgtcattgctggagtaaagccaaacatgacctgttacaaggaagaaata
ttcggtcctgtattagtgattatggaagctgagaatttgaacgaagcaacagaaattatc
aaccagaatccatacggaaacggaacagcaattttcacttcaaatggtgctactgccaga
aagtttacaaacgaggtagatgtcggacaagtcggtgtcaatgtgccaatcccggtccct
cttccgatgttctcctttactggttcacgtggatcattccttggagatatgaatttctat
ggaaaggccggcatcaatttttactcacaatggaagacagttacacaatactggaacgaa
agcttaacagagttgaagcctcaaatgtctttccctcagcttaagtga
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