Necator americanus (New World hookworm): NECAME_11271 Help Entry NECAME_11271      CDS       T04867                                  Name (RefSeq) histone methylation protein DOT1   KO K11427   [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360] Organism nai  Necator americanus (New World hookworm) Pathway nai00310   Lysine degradation nai01100   Metabolic pathways Brite KEGG Orthology (KO) [BR:nai00001]  09100 Metabolism   09105 Amino acid metabolism    00310 Lysine degradation     NECAME_11271  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:nai03036]     NECAME_11271 Enzymes [BR:nai01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.1  Methyltransferases     2.1.1.360  [histone H3]-lysine79 N-trimethyltransferase      NECAME_11271 Chromosome and associated proteins [BR:nai03036]  Eukaryotic type   Histone modification proteins    HMTs (histone methyltransferases)     HKMTs (histone lysine methyltransferases)      NECAME_11271    HMT complexes     Dot1-containing complex      NECAME_11271 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DOT1 DivIC She9_MDM33 GatB_N Motif Other DBs NCBI-GeneID:  25351300 NCBI-ProteinID:  XP_013299340 UniProt:  W2T5C2 LinkDB All DBs Position Unknown AA seq 1724 aa AA seqDB search MFSLCIKRLPCALPTIFAHLDNGASTFNNVDKTNLEEVRAVIEDFNKVAAPYAKLWKGQT NPAFESWSQDRADVELLTIICSLSFSRAVSNPQLLNNHYAPFSSGVYGETSYEQMQSIID QIGFRESDVFLDLGCGVGQLVLYVAGGTRVKRSVGIEINDLPARYGAAMGEDFSKWMKWW KKKCRPFQLFHGDMLDERFRSMITQEATIIFINNYAFEPELDLHIKNMLADCHVGTRIIS TKAYATGTKRVNMRNLGDVEAIMEVSQLKTVKQPTSWTPNNVPYYLHTVTHSKMMNFFTQ RKNGGGELSRSVSSSSKSGSRSPDSVERNRVQRSSDLVKSEGEDVHGDSDAKAHGPTTRN RWKVYVNQCEEKKKRGSPMPGSPRWNEADTDYVPPGMKKSRKSHHGNGSHHRSESSKKQA VRSRPVARVSEDAREGIEKMHAMITTPRPLDTNIDEGLVRVDIPITHNERLYSEGEELND GKSVVRIIDRETEKVLSIKNPMEAIFLSFMNQFVQFMEYMKTDSFIAALEKDIAHEKARN AELQERVRQANAAVAAQRSQGVNALYERLSDLGMSDVETPTELLQGSKQIVAHHKDLNQR VSCYETEVAMLEGKIRAVRPFGDKLIEALHSVGDNPVNIEELLQTVLQQTGNENASASLR LESENEGVEGLLMSPTGGPSNINTSHVGNTTRRPRQRPRTGPGARAKGKPEENSEEMQRQ INEIVQAALKVDSAAKEKERRSRGAERPARRSGAINSNSDSVGVPLQRTAPFPVTSRRED VEIDSVPVTVAANSSQLAYSTVTPSSGNRVIFAFFFAKLFIDPFEQINDHMDICKNELTS PFKIPLKDKEKSKNSPAVTTRSPLADAHDSREFSQRDINAIKMRQKKRIAAEQAQQARDA KKPRKPVDNPVTQDPLAVVDRICGEMAASRIKREQKRDSEERQRHVDNDSALSREALEKH AQDDTMAREFIRRESLMERLLGHKMLYGRLESYSSMGYMKTDPPPEAISTRIDPDPDFAC TSKPRRGPRTPPPPENPQLPSNDITPQRPKQPRGPKTPPGSPGPRTPPPPQPLQTSSPSV GPAMQSLLANIAAMAGTSGTQLASTLGDDLSRIVGNVNTGVFLESFVTALRSATAQNAVA PSFQTPAVQEKPPQPVTPVRDVSSRSLSRREVDTDSVKMELVSDCSLSPLRPDSQSRTQS PLKAPPAPPLIAPPPPPPILPAPSAPNASTQPPPPAPPMVSFIPIGPHSLPVQNIAMQAP PPLPPPPYAMPPNFASLPPPVPPYPGQVPPMAPPPHTAVSSISALPVSAQIPQMIPPPNI NAMPNLSMPPPGVPGQANVAQVVSAHPLPFMTPSRSSDVSATKTSSIAGTPQKPAPDMNV QNSEPPIIRVTIEDTTVNRGQQGTPAKIESRPADNWCNNNCASKFSGNFATRESQQPNRP IPGARFDPPRKPYAVDNSNNDNTQNFPGNDHSANNRGDKRVEIRPDNRPGQDHQRPQNPV PPSMKGSLAPLPSQLTKPMNSPEMTATSQSVTNTLLSALGIGSSSSGPSKSQPPSFSEQN MKKERSGQSSFLSGNSFGSEHNRLGPLGPAPRCPPGPGPVNSSGPHPRLGFTDSFGSSGP TRVCNSGLPGILGGAPSGAMGGAGIHGPSARMGSPSSPGLPSRGPLVPHSSIAPRGVPAI PPQFRGLPGIPGAHPFRPPNLPNRNIRQNRPHRGSGGRPYRPRE NT seq 5175 nt NT seq  +upstreamnt  +downstreamnt atgtttagcctatgtataaaacgtcttccgtgcgccctgccaacgatttttgctcatctg gataatggagcttccactttcaataacgtggataagacgaatttggaagaggtccgcgct gtgatagaagatttcaacaaagtcgctgctccatatgctaaactctggaaaggacaaaca aatccagcgtttgagtcgtggagccaggacagagctgatgtggagctgttgactataatt tgcagtctttcatttagccgggcggtttcaaacccccaacttctaaacaatcattatgca ccttttagcagtggggtatatggcgagacgtcgtatgaacaaatgcaatctatcattgat caaataggttttcgtgaatcagatgtctttctggatctaggttgtggagtgggacagttg gtgctgtacgttgcaggagggactagggtgaaacggtctgttggtattgaaattaacgat ttaccggcgaggtacggagcggcaatgggcgaggacttttcaaagtggatgaaatggtgg aagaaaaaatgccgtccatttcaactcttccacggcgatatgctggacgaacgattcagg agtatgattactcaggaggctacgatcatcttcatcaacaactacgctttcgagccagag ctcgatcttcacatcaaaaacatgcttgcggattgtcatgtaggtacccggatcatctca acgaaggcttatgcaacggggacgaagagagtaaatatgcggaacttgggagatgtcgaa gcaataatggaggtcagccaactgaagacagtgaaacaaccgacctcatggacaccgaac aatgtgccatattatctgcataccgtaacacatagtaagatgatgaactttttcactcag cgtaaaaatggtggtggtgagctttcgcgatcagtctcatcgtcaagcaaatcgggttcg agatctccagatagtgtggagagaaatcgtgttcagagaagcagcgatttggtcaagtca gaaggcgaagatgttcatggagatagcgacgcgaaagctcatggtcctacgactcgtaac cggtggaaagtgtatgtgaatcaatgtgaagaaaagaagaaacgaggctctccaatgcct ggaagtccacgttggaacgaagctgatacggactatgtgcctccggggatgaaaaaatcg agaaaatctcaccatggaaacggatcacatcacaggagcgaaagctcgaagaaacaagct gttcgttcacggcccgtggctcgtgtatccgaagatgctcgtgaaggtatagagaaaatg catgccatgataacaacaccacgtccattggatacgaacattgatgagggactagtacgc gttgatatacctattactcataacgagaggttgtatagtgaaggagaggagcttaacgac ggcaaatccgttgtacggatcattgacagagaaactgagaaagtgctttccatcaaaaat ccaatggaagcaattttcttgagcttcatgaaccaatttgtacagttcatggaatatatg aaaacggatagtttcattgctgcattggagaaagatattgctcacgagaaggcacgtaac gctgaattacaagagcgtgtccgtcaggcgaatgcagcggtggccgcacagagatcgcaa ggtgttaacgctctgtacgaaagattaagtgatcttgggatgagtgatgttgaaacgcca actgaactattgcaaggttccaaacaaattgtggcacatcacaaagatttgaatcaacgt gtgtcctgctatgaaacagaggtcgctatgttggaagggaaaattcgagcagttcgacca tttggtgacaagttgattgaagcccttcactctgtcggtgacaatcctgttaacattgaa gagctgctgcagacagtacttcaacagactggaaatgaaaacgcatctgcatcactgcgt ttggaatcggaaaatgaaggtgtcgagggtttgctgatgtcccctaccggtggaccatcc aatatcaacaccagtcatgtgggcaatacgacgcgtagacctcgtcaacgtcctcgaact ggacccggtgcaagagcaaaaggaaaacctgaagaaaactccgaagaaatgcaaaggcag atcaatgaaattgtgcaagcggcgttaaaggtggacagcgctgcaaaggagaaggaacgt cgttctagaggcgctgaacgtcctgctcgtcgttctggagccataaacagcaactctgac tctgtaggcgtccctctacaacgtaccgctccatttccggttacgtcacgtcgagaagat gttgagattgattctgtgccggttactgtggctgccaactcctctcaattggcttattcc accgtaacaccttcgtcaggaaacagagtcatctttgcgtttttttttgccaaattattt atcgatccatttgaacagattaatgaccatatggatatttgcaagaatgaattaacttca ccattcaaaattccgctcaaagataaggaaaaaagcaagaattcgccagctgttactacc aggtctcctttggcagatgctcatgatagtcgcgaattctctcaacgagatatcaacgca attaagatgcgacagaaaaagcggatcgctgctgaacaagctcaacaagcgcgtgatgct aagaaaccacgtaaacctgtggataaccctgtgacacaagatccactagctgtagttgat agaatttgtggtgaaatggcggcttcacgtatcaaacgagaacaaaaacgggactcagaa gagcgccaacgccatgttgataatgattccgctctcagccgggaagcccttgaaaaacat gcacaggatgatacaatggctagagagtttatccgtcgtgaatcgttaatggagcgatta cttggtcataaaatgttgtatggcaggcttgaatcgtactcgtcgatgggttacatgaaa actgatcctcctcctgaagcaatttccacgcgtattgaccctgatcccgacttcgcttgc acttcgaaaccacgtcgcggtccacgcactccaccacctccggaaaatccacaacttccc tctaatgatatcacacctcaacgtcctaaacagccaagagggccaaaaactccaccagga tcacccggtccccgaactccgccgccaccgcaacctttacagacatcttcgccttctgtg ggtcccgctatgcaatcgttgttagcaaatatagcagcaatggctgggacatcaggcact caactagcgtcaaccttaggcgacgatctgagtcgcattgttggaaatgttaatactggc gtgtttctcgaatcttttgtaactgctttgcgcagcgctacggcacaaaacgcagtggct ccaagttttcaaactcctgcggtacaagaaaaacctcctcaaccggtgactcctgttcgc gatgtgtcgtcaagatcgctttcacgacgtgaggttgatacggactcggtgaagatggag cttgtctcggattgttcgctctctcctcttcgtccagattctcaatcacgtactcaatca cctttgaaggctccaccagctccaccgcttatagctccaccaccgcctccaccaattttg ccagcaccttcagctcctaatgcttctactcagcctcctccacctgcacctcctatggtg tcgtttattccaatcgggcctcactcattacctgtccagaacattgctatgcaagctccg cctcctctgccaccaccgccctacgcaatgccgcccaatttcgcctcattaccaccacct gtgccgccgtatccgggtcaggttcccccaatggctcctcctccacacacagcagtttca tctatcagtgctttaccagtgtcagcgcaaattccacagatgatcccgccaccaaatata aatgccatgcctaacctgtctatgcccccaccaggtgttcccggtcaagcaaacgttgca caagtggtttctgcacatccgttgccgtttatgacaccatccagatcgtctgatgtatct gcaaccaaaacatcgtctatagctggtactccacaaaaaccagcaccagatatgaacgtg cagaattcggagcctcccataattcgcgtgacaattgaggacactaccgtcaatcgaggg cagcaaggaacacctgcgaaaatagaatcaagaccagcagataactggtgcaataataat tgtgctagcaaattttctgggaactttgctacccgggagagccagcagccgaacagacca atccccggagctcgtttcgatcctcccagaaaaccgtacgcggttgacaattcgaataac gacaacacccagaatttcccggggaacgaccacagtgccaacaatcgtggtgacaaacgt gttgaaattcgtccagacaatcgaccaggacaagaccatcagaggcctcaaaatccagtg cctccgtctatgaaaggatcactggctcctctaccttcgcagctgacgaagccaatgaat tctccagaaatgactgccacaagtcaaagtgtgaccaacacgttattgtcagccttgggt ataggatcttcatcttctggtccatcgaaatctcaaccaccctcgttttcggaacaaaat atgaaaaaagagcggagcggacaatctagtttcctttcagggaactcttttggtagtgaa cacaaccgtttaggtcctttgggtcctgctcctaggtgtccacccggtcctggtcctgtt aactcttcaggtccgcacccccgtctcggttttactgattcatttgggtcttcggggcca actcgagtttgtaattctggtctgcctggtattttgggtggggctccctcaggcgccatg ggaggtgcaggtattcatggcccttcagcccgcatgggatctccatcttctcctggtctt ccttcgcggggtcctctagttccacatagttcaatagctccccgaggtgttcccgctatt cctccccagtttaggggtcttcccgggattccaggtgctcatccctttcgtcctccaaac cttcccaatcgtaatattcgtcaaaatcgtccacaccgtggaagtggtggacgaccatac cgaccgcgggaatga

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