Necator americanus (New World hookworm): NECAME_11856
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Entry
NECAME_11856 CDS
T04867
Name
(RefSeq) oxidoreductase, short chain dehydrogenase/reductase family protein
KO
K04708
3-dehydrosphinganine reductase [EC:
1.1.1.102
]
Organism
nai
Necator americanus (New World hookworm)
Pathway
nai00600
Sphingolipid metabolism
nai01100
Metabolic pathways
Module
nai_M00094
Ceramide biosynthesis
nai_M00099
Sphingosine biosynthesis
Brite
KEGG Orthology (KO) [BR:
nai00001
]
09100 Metabolism
09103 Lipid metabolism
00600 Sphingolipid metabolism
NECAME_11856
Enzymes [BR:
nai01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.102 3-dehydrosphinganine reductase
NECAME_11856
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Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
3HCDH_N
THF_DHG_CYH_C
Pyr_redox_2
Motif
Other DBs
NCBI-GeneID:
25351884
NCBI-ProteinID:
XP_013298417
UniProt:
W2T2F8
LinkDB
All DBs
Position
Unknown
AA seq
853 aa
AA seq
DB search
MPLSFLMLILVVFVLLYFTLPKRRKIDLNMKHVVVTGGSKGIGRELAFCFIEKGCNVSII
ARNEADLKKAHRDLQCAADSRGQQQKVLWYSLDLSRNFDEIKDVFDRIEHELGPIHVLIN
NAGTIVQGAFDDLPLSAFEDQISLNYYTAVYPTRCVISGMKDRGFGHISFVSSAAGQFAI
WGYSSYSASKFALRGLADALQMELLPYNISVSILCPPNTDTDVFKSFHTTTMPVIMRKMT
AVAGIVSPEEVARAHVTDIENGNYLTTNGLMGWFLGVGTAGSSPEKSTLQAFAQIALAGP
VRGALLVIIGYFNALSKSYALSGKNQRETVPPSGCSDYYEELLVFAYFLVTVVYLDSFIE
LFDRFYGRRRKYADDFPVKDGRHGRFVDVLICLNFHLIFLRFRLMVSPWLALIPVGVLIV
TLILFLVLYFSTPSRKNFLLNKKHAVVTVWSSASATAFQSLSLIAKAFRHANITSVLECI
NVLYEQSQKGTRKISQGSRSAERHYVDLLKDRLVPWGNAHLDLPAGGSKGIGKQLAHSLI
SRGCNVSIIARNEKDLKAACEDLQVAADQRCQQQKVRCYSLDLVKGFTEVEAVIRRVEAE
LGPVEVLINNAGTSVQAPFHEQPITDFENQMKVNYLSAVCFFINVEYKFVNSIKVYATRC
VVPGMMSRRSGHISFVSSAAGQCAIYGYTAYAPAKFALRGFADALQMELSPYNINISLLY
PPNTDTEGFKVESATMPEETRLISEAAGLFSPEHVAEAHVKDIEGGHYATSIGLDGWMLS
VLTAGASPERNMLRAVTQVILAGLFRGIMLIYIGYFYGIVKKCYRRRKSEKETQLSEQAS
WFPVANESNKKSD
NT seq
2562 nt
NT seq
+upstream
nt +downstream
nt
atgcctctaagttttctaatgctgatactggttgtttttgtcttgctgtacttcacctta
cctaaacggagaaaaatcgatctaaatatgaaacatgttgttgttacaggaggatcgaag
ggtatcggtagagaactagcattttgttttatcgaaaaaggttgcaatgtatcaataatc
gctaggaatgaagcagatctgaagaaggctcatcgtgatttacagtgtgctgctgacagt
cgaggccagcagcaaaaggtcctgtggtactcactcgacctgagtaggaacttcgatgag
atcaaagatgtctttgaccgcatcgaacatgaacttggtcctattcatgtgctgatcaat
aacgctggtactattgtacaaggagctttcgatgatctgccgctatccgcatttgaggat
caaatatccctaaactattataccgctgtatacccaacgcggtgtgttatttctggaatg
aaggataggggttttggacacatctctttcgtttcttctgctgctggacagtttgcaatc
tggggttattcgtcatattcggcgagcaagttcgccctcagaggtcttgctgacgctctt
caaatggagttgttgccgtataatatcagcgtctcgatattatgtccacctaatacagat
acagacgtcttcaagagttttcacacaacgacaatgccagtgattatgcgtaagatgaca
gctgttgctgggatagtttctcctgaggaagtcgccagggcgcatgtgacggatatcgaa
aacggaaattacttgacaacaaatggtctcatgggatggtttctaggtgttgggacggct
ggatcttcccctgagaaaagtacgctgcaggcatttgctcagatagcacttgctgggccc
gtccgaggagctttactcgttattattggatatttcaatgcactttctaaaagttacgcg
ttgagcgggaagaaccaacgagaaactgttcctccttctgggtgttccgattattacgaa
gagttgctggtatttgcttacttccttgtaactgtcgtatatcttgattcattcatagaa
ctctttgaccgtttctacggtcgaagacgaaagtatgctgacgactttcccgtgaaggat
ggtcgccatggtcgattcgtagatgttttgatttgtttaaactttcacttgatcttcctt
cgtttcagactgatggtttctccttggttggcactgattccggtcggtgtactaatagtt
actctgatattattcttagtgctgtacttctcgactccatcacgtaaaaattttttattg
aataagaaacatgctgtagttaccgtatggtcaagcgcttctgccaccgcttttcaatca
ttgagcctcatcgccaaggcttttcggcacgcgaacatcaccagcgtgttggagtgcatc
aatgtgttatacgagcaatctcagaaaggtacgcgaaagatttcgcagggatctcggtcc
gccgaacgtcactatgtggaccttctgaaggacagattggtaccttggggtaatgctcac
ttggatctaccagcaggaggatcaaagggaattggaaaacaattagcacactctttgata
tcaagaggctgtaatgtttcaattatagcaaggaatgaaaaagacttgaaggctgcgtgt
gaggatctccaagttgctgctgatcaacgctgtcagcaacaaaaagttcgatgttactct
ctagaccttgttaaaggctttactgaggtcgaggcagttatccgccgtgttgaagcagag
ttaggccctgtggaggtgcttattaacaatgctggaacaagtgtgcaggcacccttccat
gagcaaccaattactgacttcgaaaatcaaatgaaagtcaactacttgagtgccgtatgt
ttctttataaacgtagagtataaatttgttaactcaattaaggtgtatgccacccgttgt
gtggtacctggcatgatgtccagacgctccgggcatatttcttttgtttcctcagccgct
ggtcaatgtgctatctatggttacactgcgtacgcgccggcgaaattcgccttgagagga
ttcgctgatgcactgcagatggaactcagcccttataatatcaacatctctttgctgtat
cctccaaatacggatactgaaggcttcaaggtggaatcagctacgatgcctgaagaaaca
cggttgatttctgaggctgcaggacttttctctccagagcatgttgctgaggcccatgtt
aaagacattgaaggcggacattacgctacatcgataggtcttgatggatggatgttaagt
gtgcttacagccggggcatccccagaacgtaatatgttgagagcagttactcaggttata
ctggctggattattccgaggcatcatgcttatttatataggatatttctatggcatcgtg
aagaaatgctatcgaagaagaaaatccgaaaaagaaacacagctaagtgagcaagcatct
tggtttcctgtagcgaatgagagcaacaagaagtcggattga
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