Candidatus Nanosynbacter sp. HMT-352: LR957_03540
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Entry
LR957_03540 CDS
T09649
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nanh
Candidatus Nanosynbacter sp. HMT-352
Pathway
nanh00300
Lysine biosynthesis
nanh00550
Peptidoglycan biosynthesis
nanh01100
Metabolic pathways
nanh01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nanh00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LR957_03540
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LR957_03540
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LR957_03540
Enzymes [BR:
nanh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LR957_03540
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
UHA57362
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Position
complement(658840..660129)
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AA seq
429 aa
AA seq
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MQLFKHLLETILGSYVKKYLKSHSDAKLIVVVGSVGKTSVKSATATVLSEKFTVRHSRGN
LNTTLSAPLEILGVDGPKNAKSPLAWLKVFFAAHASIKNPKSPDIIIQECGIDCPGEMAT
FMRYIQPDIAIITSVAPEHMEFFKNMDTVAHEELSISQVAKKTIFNLHDIDEKYHNLIVG
NRVSYGDEYADVFLEIKKTTDAGCIVNLKHSEETSRDVNISVLGKHNIRSITGAAAAGLA
CGMNIEEVAAALTKIRPVSGRMNILRGIRGCTLLDDTYNASPIAMENSLKTLYSISANHK
IAVLGDMNELGETSESEHKKIGEICDPSQLELLITVGKMSKKYLAPIAEKNGCKVISFDT
ALEAGKFLKNSDIKDTTILFKGSQGGIYLEDAVKELLLDPSDAEKLVRQSQSWKQIKAKF
YDSFSQSQK
NT seq
1290 nt
NT seq
+upstream
nt +downstream
nt
atgcaattattcaaacatctcttagaaacaattctcggctcttatgtaaaaaaatatctt
aaatctcattctgacgccaaactaattgtcgtagtcggcagcgttggtaaaactagtgta
aaatcagcaaccgccactgttctatcagaaaaattcaccgtgcgccatagtcgtggcaat
ttgaacacaaccttaagtgcgccgctggaaatcttaggcgtagacggaccaaaaaacgcc
aaatctcccctagcctggctaaaagtcttcttcgcagcacacgccagcataaaaaatccc
aaatctccagatataatcattcaagaatgcggcattgattgccctggtgaaatggctact
tttatgcgctatattcagcccgacattgccataattacctctgttgcccctgagcatatg
gagtttttcaaaaatatggatacggtagctcatgaggaattgtccattagtcaagtcgct
aaaaaaaccatcttcaaccttcacgatatcgatgaaaaatatcataatctcatagttgga
aatcgcgtgagttacggcgacgaatatgccgacgttttcctggaaattaaaaagactaca
gatgctggttgtattgtcaatctaaaacactccgaagaaacttctcgggatgttaacatt
tccgtattaggtaaacataatattcgctcaatcactggcgcggcggcggcaggattagct
tgcggaatgaatattgaagaagttgcggcggctttaacaaaaatcagaccagtttcagga
agaatgaatattttacgtggcatacgcggctgcacattactggacgacacttacaacgcc
agtcctattgccatggaaaattcactaaaaactctctattccatctccgctaatcacaag
attgccgtattgggagatatgaatgaactgggcgaaacatccgaatcagagcataaaaaa
atcggtgaaatttgcgatcctagccaattagagttgcttattactgttggcaaaatgtca
aaaaaatacctcgcaccaatcgctgaaaaaaatggctgtaaagtaatctcttttgatacg
gcgcttgaagctggaaaattcctgaaaaatagcgacattaaagatacgacgattctgttc
aaaggctcacagggcggcatttaccttgaagacgccgtgaaagaattactactcgaccca
agcgatgcagaaaaattagttcgccaatcacaaagctggaaacagattaaagcgaaattt
tacgactctttttctcaatctcagaaataa
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