KEGG   Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112395723
Entry
112395723         CDS       T08872                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
nasi  Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi01522  Endocrine resistance
nasi04010  MAPK signaling pathway
nasi04012  ErbB signaling pathway
nasi04014  Ras signaling pathway
nasi04024  cAMP signaling pathway
nasi04068  FoxO signaling pathway
nasi04071  Sphingolipid signaling pathway
nasi04137  Mitophagy - animal
nasi04140  Autophagy - animal
nasi04141  Protein processing in endoplasmic reticulum
nasi04210  Apoptosis
nasi04215  Apoptosis - multiple species
nasi04217  Necroptosis
nasi04310  Wnt signaling pathway
nasi04380  Osteoclast differentiation
nasi04510  Focal adhesion
nasi04530  Tight junction
nasi04620  Toll-like receptor signaling pathway
nasi04621  NOD-like receptor signaling pathway
nasi04622  RIG-I-like receptor signaling pathway
nasi04625  C-type lectin receptor signaling pathway
nasi04657  IL-17 signaling pathway
nasi04658  Th1 and Th2 cell differentiation
nasi04659  Th17 cell differentiation
nasi04660  T cell receptor signaling pathway
nasi04664  Fc epsilon RI signaling pathway
nasi04668  TNF signaling pathway
nasi04722  Neurotrophin signaling pathway
nasi04723  Retrograde endocannabinoid signaling
nasi04728  Dopaminergic synapse
nasi04750  Inflammatory mediator regulation of TRP channels
nasi04910  Insulin signaling pathway
nasi04912  GnRH signaling pathway
nasi04914  Progesterone-mediated oocyte maturation
nasi04917  Prolactin signaling pathway
nasi04920  Adipocytokine signaling pathway
nasi04926  Relaxin signaling pathway
nasi04930  Type II diabetes mellitus
nasi04931  Insulin resistance
nasi04932  Non-alcoholic fatty liver disease
nasi04933  AGE-RAGE signaling pathway in diabetic complications
nasi04935  Growth hormone synthesis, secretion and action
nasi04936  Alcoholic liver disease
nasi05010  Alzheimer disease
nasi05012  Parkinson disease
nasi05016  Huntington disease
nasi05017  Spinocerebellar ataxia
nasi05020  Prion disease
nasi05022  Pathways of neurodegeneration - multiple diseases
nasi05132  Salmonella infection
nasi05133  Pertussis
nasi05135  Yersinia infection
nasi05142  Chagas disease
nasi05145  Toxoplasmosis
nasi05152  Tuberculosis
nasi05161  Hepatitis B
nasi05162  Measles
nasi05166  Human T-cell leukemia virus 1 infection
nasi05167  Kaposi sarcoma-associated herpesvirus infection
nasi05169  Epstein-Barr virus infection
nasi05170  Human immunodeficiency virus 1 infection
nasi05171  Coronavirus disease - COVID-19
nasi05200  Pathways in cancer
nasi05208  Chemical carcinogenesis - reactive oxygen species
nasi05210  Colorectal cancer
nasi05212  Pancreatic cancer
nasi05231  Choline metabolism in cancer
nasi05415  Diabetic cardiomyopathy
nasi05417  Lipid and atherosclerosis
nasi05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nasi00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    112395723 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112395723 (MAPK8)
   04012 ErbB signaling pathway
    112395723 (MAPK8)
   04014 Ras signaling pathway
    112395723 (MAPK8)
   04310 Wnt signaling pathway
    112395723 (MAPK8)
   04668 TNF signaling pathway
    112395723 (MAPK8)
   04068 FoxO signaling pathway
    112395723 (MAPK8)
   04071 Sphingolipid signaling pathway
    112395723 (MAPK8)
   04024 cAMP signaling pathway
    112395723 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    112395723 (MAPK8)
   04137 Mitophagy - animal
    112395723 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    112395723 (MAPK8)
   04215 Apoptosis - multiple species
    112395723 (MAPK8)
   04217 Necroptosis
    112395723 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112395723 (MAPK8)
   04530 Tight junction
    112395723 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    112395723 (MAPK8)
   04621 NOD-like receptor signaling pathway
    112395723 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    112395723 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    112395723 (MAPK8)
   04660 T cell receptor signaling pathway
    112395723 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    112395723 (MAPK8)
   04659 Th17 cell differentiation
    112395723 (MAPK8)
   04657 IL-17 signaling pathway
    112395723 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    112395723 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    112395723 (MAPK8)
   04920 Adipocytokine signaling pathway
    112395723 (MAPK8)
   04912 GnRH signaling pathway
    112395723 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    112395723 (MAPK8)
   04917 Prolactin signaling pathway
    112395723 (MAPK8)
   04926 Relaxin signaling pathway
    112395723 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    112395723 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    112395723 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    112395723 (MAPK8)
   04722 Neurotrophin signaling pathway
    112395723 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    112395723 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    112395723 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112395723 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    112395723 (MAPK8)
   05231 Choline metabolism in cancer
    112395723 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    112395723 (MAPK8)
   05212 Pancreatic cancer
    112395723 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    112395723 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    112395723 (MAPK8)
   05161 Hepatitis B
    112395723 (MAPK8)
   05171 Coronavirus disease - COVID-19
    112395723 (MAPK8)
   05162 Measles
    112395723 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112395723 (MAPK8)
   05169 Epstein-Barr virus infection
    112395723 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    112395723 (MAPK8)
   05135 Yersinia infection
    112395723 (MAPK8)
   05133 Pertussis
    112395723 (MAPK8)
   05152 Tuberculosis
    112395723 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    112395723 (MAPK8)
   05142 Chagas disease
    112395723 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    112395723 (MAPK8)
   05012 Parkinson disease
    112395723 (MAPK8)
   05016 Huntington disease
    112395723 (MAPK8)
   05017 Spinocerebellar ataxia
    112395723 (MAPK8)
   05020 Prion disease
    112395723 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    112395723 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112395723 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    112395723 (MAPK8)
   05415 Diabetic cardiomyopathy
    112395723 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    112395723 (MAPK8)
   04936 Alcoholic liver disease
    112395723 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    112395723 (MAPK8)
   04931 Insulin resistance
    112395723 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    112395723 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    112395723 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nasi01001]
    112395723 (MAPK8)
Enzymes [BR:nasi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     112395723 (MAPK8)
Protein kinases [BR:nasi01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   112395723 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH DUF530
Other DBs
NCBI-GeneID: 112395723
NCBI-ProteinID: XP_024594845
UniProt: A0A341AWG0
LinkDB
Position
Unknown
AA seq 427 aa
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacagcaatttttatagtgtagagattggagattctacattc
acagtcctgaaacggtatcagaatttaaaacctataggttcaggagcccaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccggcca
tttcagaatcaaactcatgctaagcgtgcttacagagagctagttcttatgaaatgtgta
aatcacaaaaatataattggccttttgaatgtttttacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgtcaagtgattcag
atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaaa
caccttcactctgctggaattattcatcgggacttaaagcccagtaatatagtagtaaaa
tcagactgcactttgaagattcttgactttggactggccaggactgcaggaactagtttt
atgatgacaccttacgtagtgacacgctactacagagcacctgaggtcatcctagggatg
ggctacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtactgatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgtcctgaattcatgaagaaactacaaccaacagtaaggacttatgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccctgatgtacttttc
ccagctgactcggaacacaataaacttaaagccagtcaggcaagggatttgttatctaaa
atgctggtaattgatgcatctaaaaggatttctgtagatgaagctctccagcacccatat
atcaacgtctggtatgatccttctgaagcagaagctccaccaccaaagatacctgacaag
cagttagatgaaagggaacacacaatagaagagtggaaagaattgatatacaaagaagtt
atggacttggaggagagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcatcgtctgtcaatgatgtgtct
tcaatgtcaacagatccgactttggcctcggatacagacagcagtctagaagcatcagct
ggacctctgggctgctgtagatga

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