Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112395723
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Entry
112395723 CDS
T08872
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
KO
K04440
mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:
2.7.11.24
]
Organism
nasi
Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi01522
Endocrine resistance
nasi04010
MAPK signaling pathway
nasi04012
ErbB signaling pathway
nasi04014
Ras signaling pathway
nasi04024
cAMP signaling pathway
nasi04068
FoxO signaling pathway
nasi04071
Sphingolipid signaling pathway
nasi04137
Mitophagy - animal
nasi04140
Autophagy - animal
nasi04141
Protein processing in endoplasmic reticulum
nasi04210
Apoptosis
nasi04215
Apoptosis - multiple species
nasi04217
Necroptosis
nasi04310
Wnt signaling pathway
nasi04380
Osteoclast differentiation
nasi04510
Focal adhesion
nasi04530
Tight junction
nasi04620
Toll-like receptor signaling pathway
nasi04621
NOD-like receptor signaling pathway
nasi04622
RIG-I-like receptor signaling pathway
nasi04625
C-type lectin receptor signaling pathway
nasi04657
IL-17 signaling pathway
nasi04658
Th1 and Th2 cell differentiation
nasi04659
Th17 cell differentiation
nasi04660
T cell receptor signaling pathway
nasi04664
Fc epsilon RI signaling pathway
nasi04668
TNF signaling pathway
nasi04722
Neurotrophin signaling pathway
nasi04723
Retrograde endocannabinoid signaling
nasi04728
Dopaminergic synapse
nasi04750
Inflammatory mediator regulation of TRP channels
nasi04910
Insulin signaling pathway
nasi04912
GnRH signaling pathway
nasi04914
Progesterone-mediated oocyte maturation
nasi04917
Prolactin signaling pathway
nasi04920
Adipocytokine signaling pathway
nasi04926
Relaxin signaling pathway
nasi04930
Type II diabetes mellitus
nasi04931
Insulin resistance
nasi04932
Non-alcoholic fatty liver disease
nasi04933
AGE-RAGE signaling pathway in diabetic complications
nasi04935
Growth hormone synthesis, secretion and action
nasi04936
Alcoholic liver disease
nasi05010
Alzheimer disease
nasi05012
Parkinson disease
nasi05016
Huntington disease
nasi05017
Spinocerebellar ataxia
nasi05020
Prion disease
nasi05022
Pathways of neurodegeneration - multiple diseases
nasi05132
Salmonella infection
nasi05133
Pertussis
nasi05135
Yersinia infection
nasi05142
Chagas disease
nasi05145
Toxoplasmosis
nasi05152
Tuberculosis
nasi05161
Hepatitis B
nasi05162
Measles
nasi05166
Human T-cell leukemia virus 1 infection
nasi05167
Kaposi sarcoma-associated herpesvirus infection
nasi05169
Epstein-Barr virus infection
nasi05170
Human immunodeficiency virus 1 infection
nasi05171
Coronavirus disease - COVID-19
nasi05200
Pathways in cancer
nasi05208
Chemical carcinogenesis - reactive oxygen species
nasi05210
Colorectal cancer
nasi05212
Pancreatic cancer
nasi05231
Choline metabolism in cancer
nasi05415
Diabetic cardiomyopathy
nasi05417
Lipid and atherosclerosis
nasi05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nasi00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
112395723 (MAPK8)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112395723 (MAPK8)
04012 ErbB signaling pathway
112395723 (MAPK8)
04014 Ras signaling pathway
112395723 (MAPK8)
04310 Wnt signaling pathway
112395723 (MAPK8)
04668 TNF signaling pathway
112395723 (MAPK8)
04068 FoxO signaling pathway
112395723 (MAPK8)
04071 Sphingolipid signaling pathway
112395723 (MAPK8)
04024 cAMP signaling pathway
112395723 (MAPK8)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
112395723 (MAPK8)
04137 Mitophagy - animal
112395723 (MAPK8)
09143 Cell growth and death
04210 Apoptosis
112395723 (MAPK8)
04215 Apoptosis - multiple species
112395723 (MAPK8)
04217 Necroptosis
112395723 (MAPK8)
09144 Cellular community - eukaryotes
04510 Focal adhesion
112395723 (MAPK8)
04530 Tight junction
112395723 (MAPK8)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
112395723 (MAPK8)
04621 NOD-like receptor signaling pathway
112395723 (MAPK8)
04622 RIG-I-like receptor signaling pathway
112395723 (MAPK8)
04625 C-type lectin receptor signaling pathway
112395723 (MAPK8)
04660 T cell receptor signaling pathway
112395723 (MAPK8)
04658 Th1 and Th2 cell differentiation
112395723 (MAPK8)
04659 Th17 cell differentiation
112395723 (MAPK8)
04657 IL-17 signaling pathway
112395723 (MAPK8)
04664 Fc epsilon RI signaling pathway
112395723 (MAPK8)
09152 Endocrine system
04910 Insulin signaling pathway
112395723 (MAPK8)
04920 Adipocytokine signaling pathway
112395723 (MAPK8)
04912 GnRH signaling pathway
112395723 (MAPK8)
04914 Progesterone-mediated oocyte maturation
112395723 (MAPK8)
04917 Prolactin signaling pathway
112395723 (MAPK8)
04926 Relaxin signaling pathway
112395723 (MAPK8)
04935 Growth hormone synthesis, secretion and action
112395723 (MAPK8)
09156 Nervous system
04728 Dopaminergic synapse
112395723 (MAPK8)
04723 Retrograde endocannabinoid signaling
112395723 (MAPK8)
04722 Neurotrophin signaling pathway
112395723 (MAPK8)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
112395723 (MAPK8)
09158 Development and regeneration
04380 Osteoclast differentiation
112395723 (MAPK8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112395723 (MAPK8)
05208 Chemical carcinogenesis - reactive oxygen species
112395723 (MAPK8)
05231 Choline metabolism in cancer
112395723 (MAPK8)
09162 Cancer: specific types
05210 Colorectal cancer
112395723 (MAPK8)
05212 Pancreatic cancer
112395723 (MAPK8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
112395723 (MAPK8)
05170 Human immunodeficiency virus 1 infection
112395723 (MAPK8)
05161 Hepatitis B
112395723 (MAPK8)
05171 Coronavirus disease - COVID-19
112395723 (MAPK8)
05162 Measles
112395723 (MAPK8)
05167 Kaposi sarcoma-associated herpesvirus infection
112395723 (MAPK8)
05169 Epstein-Barr virus infection
112395723 (MAPK8)
09171 Infectious disease: bacterial
05132 Salmonella infection
112395723 (MAPK8)
05135 Yersinia infection
112395723 (MAPK8)
05133 Pertussis
112395723 (MAPK8)
05152 Tuberculosis
112395723 (MAPK8)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
112395723 (MAPK8)
05142 Chagas disease
112395723 (MAPK8)
09164 Neurodegenerative disease
05010 Alzheimer disease
112395723 (MAPK8)
05012 Parkinson disease
112395723 (MAPK8)
05016 Huntington disease
112395723 (MAPK8)
05017 Spinocerebellar ataxia
112395723 (MAPK8)
05020 Prion disease
112395723 (MAPK8)
05022 Pathways of neurodegeneration - multiple diseases
112395723 (MAPK8)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
112395723 (MAPK8)
05418 Fluid shear stress and atherosclerosis
112395723 (MAPK8)
05415 Diabetic cardiomyopathy
112395723 (MAPK8)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
112395723 (MAPK8)
04936 Alcoholic liver disease
112395723 (MAPK8)
04932 Non-alcoholic fatty liver disease
112395723 (MAPK8)
04931 Insulin resistance
112395723 (MAPK8)
04933 AGE-RAGE signaling pathway in diabetic complications
112395723 (MAPK8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
112395723 (MAPK8)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nasi01001
]
112395723 (MAPK8)
Enzymes [BR:
nasi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
112395723 (MAPK8)
Protein kinases [BR:
nasi01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
112395723 (MAPK8)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kdo
ABC1
RIO1
Kinase-like
FTA2
APH
DUF530
Motif
Other DBs
NCBI-GeneID:
112395723
NCBI-ProteinID:
XP_024594845
UniProt:
A0A341AWG0
LinkDB
All DBs
Position
Unknown
AA seq
427 aa
AA seq
DB search
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
atgagcagaagcaagcgtgacagcaatttttatagtgtagagattggagattctacattc
acagtcctgaaacggtatcagaatttaaaacctataggttcaggagcccaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccggcca
tttcagaatcaaactcatgctaagcgtgcttacagagagctagttcttatgaaatgtgta
aatcacaaaaatataattggccttttgaatgtttttacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgtcaagtgattcag
atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaaa
caccttcactctgctggaattattcatcgggacttaaagcccagtaatatagtagtaaaa
tcagactgcactttgaagattcttgactttggactggccaggactgcaggaactagtttt
atgatgacaccttacgtagtgacacgctactacagagcacctgaggtcatcctagggatg
ggctacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtactgatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgtcctgaattcatgaagaaactacaaccaacagtaaggacttatgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccctgatgtacttttc
ccagctgactcggaacacaataaacttaaagccagtcaggcaagggatttgttatctaaa
atgctggtaattgatgcatctaaaaggatttctgtagatgaagctctccagcacccatat
atcaacgtctggtatgatccttctgaagcagaagctccaccaccaaagatacctgacaag
cagttagatgaaagggaacacacaatagaagagtggaaagaattgatatacaaagaagtt
atggacttggaggagagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcatcgtctgtcaatgatgtgtct
tcaatgtcaacagatccgactttggcctcggatacagacagcagtctagaagcatcagct
ggacctctgggctgctgtagatga
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integrated database retrieval system