| Entry |
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| Symbol |
ABCC1
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| Name |
(RefSeq) multidrug resistance-associated protein 1 isoform X1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
nasi Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:nasi00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
112399398 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
112399398 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
112399398 (ABCC1)
04981 Folate transport and metabolism
112399398 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
112399398 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112399398 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:nasi02000]
112399398 (ABCC1)
Enzymes [BR:nasi01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
112399398 (ABCC1)
Transporters [BR:nasi02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
112399398 (ABCC1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1464 aa
MTHLNKAKTALGFLLWIVCWADLFYSFWERSLGKLLAPVFLVSPTLLGITMLLATFLIQI
ERRRGVQSSGIMLTFWLIALLCALAILRSKIMTALKEDAQVDVFRDVTFYIYFSLVLIQL
VLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGMMVQGYRQPLESTDLWSLNK
EDTSEQVVPVLVKNWKKECAKSRKQPVKIVYSSKDPAKPKGSSKVDVNEEAEALIIKSPQ
KDWNPSLFKVLYKTFGPYFLMSFLFKAVHDLMMFTGPEILKLLISFVNDRKAPDWQGYFY
TALLFVSACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNL
MSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMIFMVPLNAVMAMK
TKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLA
AVGTFTWVCTPFLVALCTFAVYVTIDKNNILDAQKAFVSLALFNILRFPLNILPMVISSI
VQASVSLKRLRIFLSHEELEPDSIQRWPIKDAGATNSITVKNATFTWARSEPPTLHGITF
SIPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNVSLRENI
LFGRQLQERYYKAVIEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDS
DIYLFDDPLSAVDAHVGKHIFENVVGPKGMLKNKTRILVTHGISYLPQVDVIIVMSGGKI
SEMGSYQELLARDGAFAEFLRTYASAEQEQGEPDDGLAGVGRPGKEMKQVENGMLVTDAV
GKQLQRQLSSSSYGGDVSRHHTSTAELQKPRPVEEDTWKLMEADKAQTGQVKLSVYWDYM
KAIGLFISFLSIFLFLCNHVASLASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQG
ITVFGYSMVVSVGGIFASRRLHLDLLHNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMI
PQVIKMFMGSLFNVIGACIIILLATPMVAVIIPPLGLIYFFVQRFYVASSRQLKRLESVS
RSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVG
NCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEY
SETEKEAPWRIQEMAPPSNWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGEKVGIVG
RTGAGKSSLTLGLFRINESAEGEIIIDDVNIAKIGLHDLRFKITIIPQDPVLFSGSLRMN
LDPFSQYSDEEVWTSLELAHLKGFVSALPHKLNHECAEGGENLSVGQRQLVCLARALLRK
TKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIRE
CGPPSGLLQQRSLFYSMAKDAGLV |
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| NT seq |
4395 nt +upstreamnt +downstreamnt
atgacacatctcaacaaagccaaaactgccttgggatttttgctatggattgtctgctgg
gcagacctcttctactctttctgggaaagaagtttgggcaagctcctggccccagtgttt
ctggtcagcccaaccctcttgggcatcaccatgctgcttgctacctttttaattcagatc
gagagaaggaggggagttcagtcctcagggatcatgctcactttctggcttatagcccta
ctgtgtgccctggccatcctgagatccaaaatcatgactgccttaaaagaggatgcccaa
gtcgacgtctttcgcgatgtcactttctacatttacttctccctcgtgctgatccagctt
gtgttgtcctgcttctcagaccgctcacccctgttctccgaaaccatccacgatcccaat
ccttgcccagaatccagcgcctccttcctttccaggatcaccttctggtggatcacaggg
atgatggtccagggctaccgccaacccctggagagcactgacctctggtccctgaataag
gaggatacgtcagaacaagttgtgcccgttttggtaaagaactggaagaaggaatgtgca
aagtccagaaaacagccggtgaagatcgtgtactcctccaaggatcccgccaagccgaaa
gggagttccaaggtggatgtgaacgaggaggccgaggctttgatcatcaagtccccccag
aaggattggaacccgtccctgttcaaggtgttatacaagacatttgggccctacttcctc
atgagcttcttgttcaaggctgtgcacgacctgatgatgtttaccggcccagagatctta
aagttgctcatcagcttcgtgaacgacaggaaggccccagactggcagggctacttctac
acggcgctgctgttcgtcagcgcctgcctgcagaccctcgtgctgcaccagtacttccac
atctgcttcgtcagcggcatgcggatcaagaccgccgtcatcggggctgtgtaccggaag
gccctggtgatcaccaattcagccagaaaatcgtccaccgtcggggagatcgtcaacctc
atgtctgtggatgcccagaggttcatggacctggccacgtacattaacatgatctggtca
gctcctctgcaagtcatccttgccctctacctcctgtggctgaacctgggcccctccgtt
ctggctggagtggctgtgatgatcttcatggttcccctcaatgcagtgatggccatgaag
accaagacctaccaggtggcccacatgaagagcaaagacaatcggattaagctgatgaat
gaaattctgaatgggatcaaagtgctaaagctttacgcctgggagctggcattcaaagat
aaggtgctggccatcaggcaggaggagctgaaggtgctgaagaaatctgcctacctggcc
gccgtggggaccttcacctgggtctgcacacctttcctggtggccttgtgcacgtttgcc
gtctacgtgaccatcgacaagaacaacatcctggatgcccagaaggccttcgtgtccttg
gccttgttcaacatccttcgcttccccctgaatattctccccatggtcatcagcagcatc
gtgcaggcgagtgtctccctcaagcgcctcaggatcttcctctcccacgaggagctggaa
cccgacagcatccagcgatggcccatcaaagacgctggggccacaaacagcatcactgtg
aagaatgccacgttcacttgggccaggagcgagcctcccacgctgcatggcatcactttc
tccattccggaaggttccctggtggccgtggtgggccaggtgggctgtgggaagtcgtct
ctgctctcagcgctcttggctgagatggacaaggtggagggacacgtggctatcaagggt
tcagtggcctacgtcccccagcaggcctggattcagaatgtttctctccgagaaaacatc
ctttttggacgccagctacaggaacggtattataaggctgtgatagaagcctgtgccctc
ctcccagacctggaaatcctgcccagtggggaccggacagagattggtgagaagggcgtg
aacctgtctggcggccagaagcaacgcgtgagcctggcccgggccgtgtattgcgactcc
gacatctacctctttgacgatcccctctcggcggtggatgcccacgtggggaagcacata
tttgaaaacgtggttggccccaaggggatgctgaagaacaagacgcggatcctggtcacg
cacggcatcagctacctgccccaggtggatgtcatcatcgtcatgagtggtggcaagatc
tccgagatgggctcctaccaggagctgctggcccgggacggggcctttgccgagttcctg
cgcacgtacgccagcgccgagcaggagcagggggagcccgacgacggcttagcaggtgtt
ggcaggccagggaaggagatgaagcaggtggagaacggcatgctggtgacggacgctgtg
gggaagcaactgcagagacagctcagcagctcctcctatggcggggatgtcagccggcac
cacaccagcaccgcggagctgcagaagcccaggcccgtggaggaggacacctggaagctg
atggaggcagacaaggctcagactgggcaggtcaagctctccgtgtactgggactacatg
aaggcgataggacttttcatctcctttctgagcatcttccttttcctgtgtaaccacgtt
gcttctctggcctctaactattggctcagtctctggactgatgaccccatcgtcaatggg
acccaggagcacacgaaagtccggctgagcgtctatggagccctgggcatttctcaaggt
atcacagtgttcggctactccatggtggtgtccgtcgggggcatcttcgcctcgcgccgc
ctgcacctggacctgctgcataacgtcctcaggtcgcccatgagcttcttcgagcggacc
cccagcgggaacctggtgaaccgcttctccaaggagctggacacagtggactcgatgatc
cctcaggtcatcaagatgttcatgggctccctgttcaacgtcattggcgcctgcatcatc
atcctgctggccactcccatggtggccgtcatcatcccgcccctgggcctcatctacttc
tttgtccagaggttctacgtggcctcctcccggcagctgaagcgcctcgagtcagtcagc
cgctcccccgtttattcccacttcaacgagaccctgctgggggtcagcgtcatccgcgcc
ttcgaggaacaggagcgcttcatccgccagagcgacctgaaggtggacgagaaccagaag
gcctattaccccagcattgtggccaacaggtggctggctgtgcggctggagtgtgtaggc
aactgcattgtcctgtttgccgccctgtttgcagtgatctcccggcacagtctcagtgct
ggcttggtgggcctctcggtgtcttactcactgcaggtcaccacgtacttgaactggctt
gttcggatgtcgtccgagatggagaccaacattgtggccgtggagagactcaaggagtat
tcagagactgagaaggaggctccctggcgaatccaggagatggcaccccccagcaactgg
ccccaggtgggccgagtggagttccgagactacggcctgcgttaccgagaggacctggac
ctggttctcaagcacatcaacgtcaccatcgatggaggggagaaggttggcatcgtgggg
cggacaggagctgggaagtcatccctgaccctgggcttgtttcgtatcaacgagtctgcc
gagggagagatcatcattgacgatgtcaacattgccaagatcggcctgcacgacctccgc
ttcaagatcaccatcatcccccaggaccccgttttgttttcgggttccctccgcatgaac
ctggacccattcagccagtattcagatgaagaggtctggacgtctctggagctggcccac
ctgaagggcttcgtgtcggcccttccccataagctgaaccacgagtgcgcagaaggcggg
gagaacctcagcgtcgggcagcgccagcttgtctgcctggcccgggccctgctgaggaag
acgaagatccttgtgttggatgaggccacggcggctgtggacctggaaacggatgacctc
attcagtccaccatccggacacagtttgacgactgtaccgtcctcaccattgctcaccgg
ctcaacaccatcatggactacacgagggtgattgtcctggacaaaggggagatccgggag
tgtggtcccccctccggcctcctgcaacagagaagtctcttctacagcatggccaaagat
gctggcttggtgtga |
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