KEGG   Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112401344
Entry
112401344         CDS       T08872                                 
Symbol
GCK
Name
(RefSeq) glucokinase isoform X1
  KO
K12407  glucokinase [EC:2.7.1.2]
Organism
nasi  Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi00010  Glycolysis / Gluconeogenesis
nasi00052  Galactose metabolism
nasi00500  Starch and sucrose metabolism
nasi00520  Amino sugar and nucleotide sugar metabolism
nasi00524  Neomycin, kanamycin and gentamicin biosynthesis
nasi01100  Metabolic pathways
nasi01200  Carbon metabolism
nasi01250  Biosynthesis of nucleotide sugars
nasi04910  Insulin signaling pathway
nasi04911  Insulin secretion
nasi04917  Prolactin signaling pathway
nasi04922  Glucagon signaling pathway
nasi04930  Type II diabetes mellitus
nasi04950  Maturity onset diabetes of the young
nasi05230  Central carbon metabolism in cancer
Module
nasi_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
nasi_M00549  UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:nasi00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    112401344 (GCK)
   00052 Galactose metabolism
    112401344 (GCK)
   00500 Starch and sucrose metabolism
    112401344 (GCK)
  09107 Glycan biosynthesis and metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    112401344 (GCK)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    112401344 (GCK)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    112401344 (GCK)
   04910 Insulin signaling pathway
    112401344 (GCK)
   04922 Glucagon signaling pathway
    112401344 (GCK)
   04917 Prolactin signaling pathway
    112401344 (GCK)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    112401344 (GCK)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    112401344 (GCK)
   04950 Maturity onset diabetes of the young
    112401344 (GCK)
Enzymes [BR:nasi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     112401344 (GCK)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1
Other DBs
NCBI-GeneID: 112401344
NCBI-ProteinID: XP_024603348
UniProt: A0A341BNK4
LinkDB
Position
Unknown
AA seq 537 aa
MLCPRDQPGLTLCSAGPALGPSGSLWPQETGSLHLTMRNWFPTVIWGTPSPILSLGHFPR
SSGRPWAGGDFSPRQGIPAAFPSSPLPSPQFILGSPRCLASGAPRPALLVPPPCLPLLLS
QSWGLLPGGAHETDVLLSVAAEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMY
SIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWT
KGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGT
GCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQL
FEKLIGGKYMGELVRLVLLKLVDENLLFHGEASEKLRTRGAFETRFVSQVESDSGDRKQI
YNILSTLGLRPSATDCDIVRRACESVSTRAARMCAAGLAGVINRMRESRSEDVMRITVGV
DGSVYKLHPSFKERFHASVRRLTPSCEITFIESEEGSGRGAALISAVACKKACMLGQ
NT seq 1614 nt   +upstreamnt  +downstreamnt
atgctgtgccccagggaccagccaggtctcaccctctgttccgctggccccgccctgggg
ccttcaggctcactctggcctcaggaaactggctctcttcatctcacaatgagaaactgg
tttcccacagtcatttgggggactcccagcccaatcctgagtctgggccattttcctagg
tcttcaggtaggccctgggctgggggcgacttcagcccaagacaagggattcctgctgcc
ttccccagttcacctttgccctctccacagtttatcctggggtcccccagatgtctggca
tcgggggcccctcgtccagctcttctggtccccccaccatgccttcccctcctcctctcc
cagtcttgggggctcctgcccggcggtgcccatgagactgatgtacttctctctgtggct
gcagaagtcggggatttcctctccctggacctgggcggcaccaacttcagggtgatgctt
gtgaaggtgggggaaggggaggagggacagtggagtgtgaaaaccaagcaccagatgtac
tccatccccgaggacgccatgacgggcactgctgagatgctctttgactacatctctgag
tgcatctccgacttcctggacaagcatcagatgaagcacaagaagctgcccttgggcttc
accttctcctttcctgtgaggcacgaagacatcgacaagggcatccttctcaactggacc
aagggcttcaaggcctcaggagcagaagggaacaacatcgtggggctcctgcgagatgcc
atcaaacggagaggggactttgagatggacgtggtggcgatggtgaacgacactgtggcc
acgatgatctcctgctactatgaagaccgccggtgtgaggttggcatgattgtgggcacg
ggctgcaacgcctgctacatggaggagatgcagaacgtggagctggtggaaggggacgag
ggccgcatgtgtgtcaacaccgagtggggtgccttcggggactcgggcgagctggacgag
ttcctgctggagtacgaccgtgtggtggacgagaactccctgaaccccggccagcagctg
ttcgagaagctcatcggcggcaagtacatgggcgagctggtgcggctcgtgctgctgaag
cttgtggacgagaacctactcttccacggggaggcctcggagaagctgcgcacgcgtggc
gccttcgagacacgcttcgtgtcgcaggtggagagtgactcgggcgaccgcaagcagatc
tacaacatcctgagcacgctggggctgaggccgtcggccaccgactgcgacatcgtgcgc
cgcgcctgcgagagcgtgtccacccgcgccgcgcgcatgtgcgccgcggggctggcgggc
gtcatcaaccgcatgcgcgagagccgcagcgaggacgtgatgcgcatcaccgtgggcgtg
gacggctcagtgtacaagctgcaccccagcttcaaggagcggttccacgccagcgtgcgc
aggctgacgcccagctgtgaaatcaccttcatcgagtcggaggagggcagcggccggggt
gcggccttgatctccgcggtggcctgtaagaaggcctgcatgctgggccagtga

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