Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112403943
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Entry
112403943 CDS
T08872
Symbol
BACE1
Name
(RefSeq) beta-secretase 1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
nasi
Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
nasi00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
112403943 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
nasi01002
]
112403943 (BACE1)
Enzymes [BR:
nasi01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
112403943 (BACE1)
Peptidases and inhibitors [BR:
nasi01002
]
Aspartic peptidases
Family A1: pepsin family
112403943 (BACE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
112403943
NCBI-ProteinID:
XP_024607454
UniProt:
A0A341BZ12
LinkDB
All DBs
Position
Unknown
AA seq
498 aa
AA seq
DB search
MAQALPWLLLWMGSGVLPAHGSQPGIRLPLRSGLGGAPLGLRLPRETDEEPSRRGSFVEM
VDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRD
LRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLA
YAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHS
LYMGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFE
AAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILP
QQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRAQKRIGFAVSACHVH
DEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCL
RCLRHQHDDFADDISLLK
NT seq
1497 nt
NT seq
+upstream
nt +downstream
nt
atggcccaagcgctgccctggctcctgctgtggatgggctctggggtgctgcctgcccac
ggctcccagcctggcatccggctgcccctgcgaagcgggctggggggcgcccccctgggg
ctgcggctgccccgagagaccgacgaggagcccagccggaggggcagctttgtggagatg
gtggacaacctgaggggcaagtccggtcagggctactacgtggagatgaccgtgggcagc
cccccacagacgctcaacatcctggtggacacaggcagcagtaacttcgcagttggggcc
gccccccaccctttcctgcaccgctactaccagaggcagctgtccagtacataccgggac
ctccggaagggcgtgtatgtgccctacacccagggcaagtgggaaggggagctgggcacc
gacctggtgagcatcccccacggccccaatgtcaccgttcgtgccaacatcgctgccatc
actgaatcagacaagttcttcatcaatggctccaactgggagggcatcctggggctggcc
tacgctgagatcgccaggcctgacgactccctggagccattctttgactcgttggtaaag
cagacccacgtgcccaatctcttctccctgcagctctgtggtgctggcttccccctcaac
cagtcggaggtgctggcctcagttggagggagcatgatcatcgggggtatcgaccactcg
ctgtacatgggcagcctctggtacacacccatccggcgggaatggtattacgaggtgatc
attgtgcgggtggagatcaatggacaggatctgaaaatggactgcaaggagtacaactat
gacaagagcatcgttgacagtggcaccactaaccttcgtttgcccaagaaagtgtttgaa
gctgctgtcaaatccatcaaggcagcctcctcgacggagaagttcccagacggtttctgg
ctcggggagcagctggtgtgctggcaagcaggcaccaccccttggaacattttcccggtc
atctcactctacctaatgggtgaggtcaccaatcagtccttccgaatcaccatccttcca
cagcaatacctgcggccagtggaagatgtggccacgtcccaagacgactgttacaagttc
gccatctcacagtcatccacgggcactgtcatgggagccgttatcatggagggcttctac
gttgtctttgatcgggcccagaaacgaattggctttgctgtcagtgcttgccatgtgcac
gatgagttcaggacagcagcggtagaaggtccttttgtcaccctggacatggaagactgt
ggctacaacatcccacagacagatgaatcgaccctcatgaccatagcctatgtcatggct
gccatctgtgccctcttcatgctgcccctctgcctcatggtgtgtcagtggcgctgcctc
cgctgcctgcgccatcagcacgatgactttgctgatgacatctccctgctgaagtga
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