Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112407243
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Entry
112407243 CDS
T08872
Symbol
RAF1
Name
(RefSeq) RAF proto-oncogene serine/threonine-protein kinase isoform X1
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
nasi
Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi01521
EGFR tyrosine kinase inhibitor resistance
nasi01522
Endocrine resistance
nasi04010
MAPK signaling pathway
nasi04012
ErbB signaling pathway
nasi04014
Ras signaling pathway
nasi04015
Rap1 signaling pathway
nasi04022
cGMP-PKG signaling pathway
nasi04024
cAMP signaling pathway
nasi04062
Chemokine signaling pathway
nasi04068
FoxO signaling pathway
nasi04071
Sphingolipid signaling pathway
nasi04072
Phospholipase D signaling pathway
nasi04140
Autophagy - animal
nasi04150
mTOR signaling pathway
nasi04151
PI3K-Akt signaling pathway
nasi04210
Apoptosis
nasi04218
Cellular senescence
nasi04270
Vascular smooth muscle contraction
nasi04360
Axon guidance
nasi04370
VEGF signaling pathway
nasi04371
Apelin signaling pathway
nasi04510
Focal adhesion
nasi04540
Gap junction
nasi04550
Signaling pathways regulating pluripotency of stem cells
nasi04613
Neutrophil extracellular trap formation
nasi04625
C-type lectin receptor signaling pathway
nasi04630
JAK-STAT signaling pathway
nasi04650
Natural killer cell mediated cytotoxicity
nasi04660
T cell receptor signaling pathway
nasi04662
B cell receptor signaling pathway
nasi04664
Fc epsilon RI signaling pathway
nasi04666
Fc gamma R-mediated phagocytosis
nasi04720
Long-term potentiation
nasi04722
Neurotrophin signaling pathway
nasi04726
Serotonergic synapse
nasi04730
Long-term depression
nasi04810
Regulation of actin cytoskeleton
nasi04910
Insulin signaling pathway
nasi04912
GnRH signaling pathway
nasi04914
Progesterone-mediated oocyte maturation
nasi04915
Estrogen signaling pathway
nasi04916
Melanogenesis
nasi04917
Prolactin signaling pathway
nasi04919
Thyroid hormone signaling pathway
nasi04921
Oxytocin signaling pathway
nasi04926
Relaxin signaling pathway
nasi04928
Parathyroid hormone synthesis, secretion and action
nasi04929
GnRH secretion
nasi04935
Growth hormone synthesis, secretion and action
nasi05010
Alzheimer disease
nasi05022
Pathways of neurodegeneration - multiple diseases
nasi05034
Alcoholism
nasi05132
Salmonella infection
nasi05152
Tuberculosis
nasi05160
Hepatitis C
nasi05161
Hepatitis B
nasi05163
Human cytomegalovirus infection
nasi05164
Influenza A
nasi05165
Human papillomavirus infection
nasi05167
Kaposi sarcoma-associated herpesvirus infection
nasi05170
Human immunodeficiency virus 1 infection
nasi05200
Pathways in cancer
nasi05205
Proteoglycans in cancer
nasi05206
MicroRNAs in cancer
nasi05207
Chemical carcinogenesis - receptor activation
nasi05208
Chemical carcinogenesis - reactive oxygen species
nasi05210
Colorectal cancer
nasi05211
Renal cell carcinoma
nasi05212
Pancreatic cancer
nasi05213
Endometrial cancer
nasi05214
Glioma
nasi05215
Prostate cancer
nasi05218
Melanoma
nasi05219
Bladder cancer
nasi05220
Chronic myeloid leukemia
nasi05221
Acute myeloid leukemia
nasi05223
Non-small cell lung cancer
nasi05224
Breast cancer
nasi05225
Hepatocellular carcinoma
nasi05226
Gastric cancer
nasi05230
Central carbon metabolism in cancer
nasi05231
Choline metabolism in cancer
nasi05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
nasi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112407243 (RAF1)
04012 ErbB signaling pathway
112407243 (RAF1)
04014 Ras signaling pathway
112407243 (RAF1)
04015 Rap1 signaling pathway
112407243 (RAF1)
04370 VEGF signaling pathway
112407243 (RAF1)
04371 Apelin signaling pathway
112407243 (RAF1)
04630 JAK-STAT signaling pathway
112407243 (RAF1)
04068 FoxO signaling pathway
112407243 (RAF1)
04072 Phospholipase D signaling pathway
112407243 (RAF1)
04071 Sphingolipid signaling pathway
112407243 (RAF1)
04024 cAMP signaling pathway
112407243 (RAF1)
04022 cGMP-PKG signaling pathway
112407243 (RAF1)
04151 PI3K-Akt signaling pathway
112407243 (RAF1)
04150 mTOR signaling pathway
112407243 (RAF1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
112407243 (RAF1)
09143 Cell growth and death
04210 Apoptosis
112407243 (RAF1)
04218 Cellular senescence
112407243 (RAF1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
112407243 (RAF1)
04540 Gap junction
112407243 (RAF1)
04550 Signaling pathways regulating pluripotency of stem cells
112407243 (RAF1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
112407243 (RAF1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
112407243 (RAF1)
04625 C-type lectin receptor signaling pathway
112407243 (RAF1)
04650 Natural killer cell mediated cytotoxicity
112407243 (RAF1)
04660 T cell receptor signaling pathway
112407243 (RAF1)
04662 B cell receptor signaling pathway
112407243 (RAF1)
04664 Fc epsilon RI signaling pathway
112407243 (RAF1)
04666 Fc gamma R-mediated phagocytosis
112407243 (RAF1)
04062 Chemokine signaling pathway
112407243 (RAF1)
09152 Endocrine system
04910 Insulin signaling pathway
112407243 (RAF1)
04929 GnRH secretion
112407243 (RAF1)
04912 GnRH signaling pathway
112407243 (RAF1)
04915 Estrogen signaling pathway
112407243 (RAF1)
04914 Progesterone-mediated oocyte maturation
112407243 (RAF1)
04917 Prolactin signaling pathway
112407243 (RAF1)
04921 Oxytocin signaling pathway
112407243 (RAF1)
04926 Relaxin signaling pathway
112407243 (RAF1)
04935 Growth hormone synthesis, secretion and action
112407243 (RAF1)
04919 Thyroid hormone signaling pathway
112407243 (RAF1)
04928 Parathyroid hormone synthesis, secretion and action
112407243 (RAF1)
04916 Melanogenesis
112407243 (RAF1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
112407243 (RAF1)
09156 Nervous system
04726 Serotonergic synapse
112407243 (RAF1)
04720 Long-term potentiation
112407243 (RAF1)
04730 Long-term depression
112407243 (RAF1)
04722 Neurotrophin signaling pathway
112407243 (RAF1)
09158 Development and regeneration
04360 Axon guidance
112407243 (RAF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112407243 (RAF1)
05206 MicroRNAs in cancer
112407243 (RAF1)
05205 Proteoglycans in cancer
112407243 (RAF1)
05207 Chemical carcinogenesis - receptor activation
112407243 (RAF1)
05208 Chemical carcinogenesis - reactive oxygen species
112407243 (RAF1)
05230 Central carbon metabolism in cancer
112407243 (RAF1)
05231 Choline metabolism in cancer
112407243 (RAF1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
112407243 (RAF1)
09162 Cancer: specific types
05210 Colorectal cancer
112407243 (RAF1)
05212 Pancreatic cancer
112407243 (RAF1)
05225 Hepatocellular carcinoma
112407243 (RAF1)
05226 Gastric cancer
112407243 (RAF1)
05214 Glioma
112407243 (RAF1)
05221 Acute myeloid leukemia
112407243 (RAF1)
05220 Chronic myeloid leukemia
112407243 (RAF1)
05218 Melanoma
112407243 (RAF1)
05211 Renal cell carcinoma
112407243 (RAF1)
05219 Bladder cancer
112407243 (RAF1)
05215 Prostate cancer
112407243 (RAF1)
05213 Endometrial cancer
112407243 (RAF1)
05224 Breast cancer
112407243 (RAF1)
05223 Non-small cell lung cancer
112407243 (RAF1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
112407243 (RAF1)
05161 Hepatitis B
112407243 (RAF1)
05160 Hepatitis C
112407243 (RAF1)
05164 Influenza A
112407243 (RAF1)
05163 Human cytomegalovirus infection
112407243 (RAF1)
05167 Kaposi sarcoma-associated herpesvirus infection
112407243 (RAF1)
05165 Human papillomavirus infection
112407243 (RAF1)
09171 Infectious disease: bacterial
05132 Salmonella infection
112407243 (RAF1)
05152 Tuberculosis
112407243 (RAF1)
09164 Neurodegenerative disease
05010 Alzheimer disease
112407243 (RAF1)
05022 Pathways of neurodegeneration - multiple diseases
112407243 (RAF1)
09165 Substance dependence
05034 Alcoholism
112407243 (RAF1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112407243 (RAF1)
01522 Endocrine resistance
112407243 (RAF1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nasi01001
]
112407243 (RAF1)
Enzymes [BR:
nasi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
112407243 (RAF1)
Protein kinases [BR:
nasi01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
112407243 (RAF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RBD
C1_1
Kinase-like
ABC1
zf-RING-like
Pkinase_fungal
C1_2
Motif
Other DBs
NCBI-GeneID:
112407243
NCBI-ProteinID:
XP_024612205
UniProt:
A0A341CBZ0
LinkDB
All DBs
Position
Unknown
AA seq
648 aa
AA seq
DB search
MEHIQGAWKTISNGFGFKDAVFDGPSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRV
FLPNKQRTVVNVRNGMSLQDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSIVGDSGFPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTF
NTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHGESASPSALSSSPNNL
SPTGWSQPKTPVPAQRERAPGSSAQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF
GTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIV
TQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGL
TVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDNNPFSFQSDVYSYGIVLYE
LMTGELPYSHISNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFP
QILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
NT seq
1947 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacagggggcctggaagacgatcagcaatggttttggattcaaagacgct
gtgtttgatggccccagctgcatctcccctacaatagttcagcagtttggctatcagcgt
cgggcatcagatgatggcaaacttacggacccttctaagacaagcaacactatccgtgtt
tttttgccaaacaagcaaagaacagtggtcaatgtgcggaatggaatgagcttgcaagac
tgccttatgaaagctctcaaggtgaggggcctgcaaccagagtgctgtgcagttttcaga
cttctccacgaacacaagggtaaaaaagcacgtttagattggaatactgatgctgcctcg
ttgattggagaggaacttcaagtagatttcctggatcatgttccactcacaacacacaac
tttgctcggaagaccttcctgaaacttgccttctgtgacatctgtcagaagttcctgcta
aatgggtttagatgtcagacttgtggctacaagtttcacgagcattgtagcaccaaagta
cctactatgtgtgtggactggagtaatatcagacaactcttgctgttcccaaattccatt
gttggtgatagtgggttcccagcactgccttctttgacaatgcgtcggatgcgagagtct
gtctcccggatgcctgttagttcccagcacagatactccacaccccacgctttcacattc
aacacctccagcccctcctctgaaggttccctctctcagaggcagaggtcgacgtccaca
cctaatgtccacatggtcagcaccaccttgcccgtggacagcaggatgattgaggatgca
attcgaagtcacggtgaatcagcctcaccttcagccttgtccagcagtcccaacaatctg
agcccaacaggctggtcacagcccaaaacccctgtgccggcacagagagagcgggcaccg
ggatccagcgcccaggagaagaataaaattaggcctcgtggacagagagattcaagctat
tactgggaaatagaagccagtgaagtgatgctctccactcggattgggtcaggctccttt
gggactgtttataagggcaagtggcatggagacgttgcagtaaagattctaaaggttgtt
gaccccacaccagagcagttccaggccttcaggaatgaagtggctgtccttcgcaaaacc
cggcacgtgaacatcctgctcttcatggggtacatgacgaaggacaacctggcaattgtg
acccagtggtgcgagggcagcagcctctataaacacctgcacgtccaggagaccaagttc
cagatgttccagttgattgacattgcccggcagacggctcagggaatggactacttgcat
gcaaagaacatcatccacagagacatgaaatccaacaatatatttctccatgaaggcctg
acggtgaaaattggagactttggtttggcaacagtgaagtcgcgctggagtggttctcag
caggttgaacaacccaccggctccatcttgtggatggccccagaggtgattcgaatgcag
gacaataacccgttcagcttccagtctgacgtctactcttacggcatcgtgctatacgag
cttatgacgggggagctgccctactcccacatcagcaaccgcgatcagatcatcttcatg
gtaggccgagggtacgcctccccagaccttagtaagctgtacaagaactgccccaaagca
atgaagaggctggtagccgactgtgtgaagaaagttaaggaagagaggcctctttttccc
cagatcctgtcttccattgagctgctccaacactctctaccgaaaatcaaccggagcgct
tctgagccatccctgcaccgggcggcccataccgaggacatcaatgcctgcacgctgacc
acatcccctagattgcctgtcttctag
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