KEGG   Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112408295
Entry
112408295         CDS       T08872                                 
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
  KO
K04514  Rho-associated protein kinase 1 [EC:2.7.11.39]
Organism
nasi  Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi04022  cGMP-PKG signaling pathway
nasi04024  cAMP signaling pathway
nasi04062  Chemokine signaling pathway
nasi04071  Sphingolipid signaling pathway
nasi04270  Vascular smooth muscle contraction
nasi04350  TGF-beta signaling pathway
nasi04360  Axon guidance
nasi04510  Focal adhesion
nasi04520  Adherens junction
nasi04530  Tight junction
nasi04611  Platelet activation
nasi04670  Leukocyte transendothelial migration
nasi04810  Regulation of actin cytoskeleton
nasi04921  Oxytocin signaling pathway
nasi05135  Yersinia infection
nasi05163  Human cytomegalovirus infection
nasi05200  Pathways in cancer
nasi05205  Proteoglycans in cancer
nasi05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:nasi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    112408295 (ROCK1)
   04071 Sphingolipid signaling pathway
    112408295 (ROCK1)
   04024 cAMP signaling pathway
    112408295 (ROCK1)
   04022 cGMP-PKG signaling pathway
    112408295 (ROCK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112408295 (ROCK1)
   04520 Adherens junction
    112408295 (ROCK1)
   04530 Tight junction
    112408295 (ROCK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    112408295 (ROCK1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    112408295 (ROCK1)
   04670 Leukocyte transendothelial migration
    112408295 (ROCK1)
   04062 Chemokine signaling pathway
    112408295 (ROCK1)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    112408295 (ROCK1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    112408295 (ROCK1)
  09158 Development and regeneration
   04360 Axon guidance
    112408295 (ROCK1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112408295 (ROCK1)
   05206 MicroRNAs in cancer
    112408295 (ROCK1)
   05205 Proteoglycans in cancer
    112408295 (ROCK1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    112408295 (ROCK1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    112408295 (ROCK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nasi01001]
    112408295 (ROCK1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:nasi03036]
    112408295 (ROCK1)
Enzymes [BR:nasi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.39  ROCK-subfamily protein kinase
     112408295 (ROCK1)
Protein kinases [BR:nasi01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   112408295 (ROCK1)
Chromosome and associated proteins [BR:nasi03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    112408295 (ROCK1)
SSDB
Motif
Pfam: Rho_Binding Pkinase PH C1_1 Cortex-I_coil Pkinase_C FPP
Other DBs
NCBI-GeneID: 112408295
NCBI-ProteinID: XP_024613658
UniProt: A0A341CGJ9
LinkDB
Position
Unknown
AA seq 1132 aa
MNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADS
LVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQ
WAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSN
RRYLSSANPNENRTSSNVDKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDK
IMKELDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQ
LEDLKKVSQNSHLANEKLAQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSITQLESLN
RELQERNRILENSKSQMDKDYYQLQAVLEAERRDRGHDSEMIGDLQARNTSLQEEVKHLK
HNLERAEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKH
QSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENK
ERMEDEVKNLSLQLEQESNKRLLLQNELKTHAFEADNLKGLEKQMKQEINTLLEAKRLLE
FELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENSKKIQELQ
SEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNRQEITDKEHTVSRLE
ETNSMLTKDIELLRKENEELADKMKKAEEEYKLKKEEEINNLKAAFEKNINTERTLKTQA
VNKLAEIMNRKDFKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDM
QAQLVEECTHRNELQMQLASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIE
GWLSIPNRGNIKRYGWKKQYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQG
DVYRAETEEIPKIFQILYANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANC
EACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQ
DEQKKWVTHLVKKIPKNPPSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS
NT seq 3399 nt   +upstreamnt  +downstreamnt
atgaataaggaaggtatggtacgatgtgatacagcagttgggacacctgattatatttcc
cctgaagtattaaaatctcaaggtggtgatggttattatggacgagaatgtgactggtgg
tcagttggggtatttttatatgaaatgcttgtaggtgatacaccattttatgcagattct
ctggttggaacttacagtaagattatgaaccataaaaattcacttaccttccctgatgat
aatgacatatcaaaagaagcaaaaaatcttatttgtgccttccttactgacagagaggtg
agattagggcggaatggtgtagaagaaatcaaacgacatctcttcttcaaaaatgatcag
tgggcttgggaaacactccgagacactgtagcgccagttgtacctgatttaagtagtgac
attgacacaagtaactttgatgacttggaagaagataaaggagatgaagaaacattccct
atacctaaagcttttgttggcaatcaactaccctttgtaggatttacgtattatagcaat
cgtagatacttatcttcagcaaatcctaatgaaaacagaactagctctaatgtggataaa
agcttgcaggaaaatttgcaaaaaacaatttataagctggaagaacagttgcataatgaa
atgcaattaaaagatgaaatggagcagaagtgcagaacttcaaacataaaactcgacaag
ataatgaaagaattggatgaagaggggaatcaaagaagaaacctagaatctacagtgtct
cagattgagaaggagaaaatgttgctacagcatagaattaatgagtaccaaagaaaagca
gaacaggaaaatgagaagaggaggaatgtagaaaatgaagtttctacattaaaggatcag
ttggaagacttaaagaaagtcagtcagaattcacaccttgctaatgagaaactggcacaa
ttacaaaagcagctagaagaagccaatgacttacttaggacagaatcagacacagctgta
agattaaggaagagtcacaccgagatgagcaaatcaattactcagctagagtccctgaat
agagaattgcaggagagaaatagaattttggagaattccaagtcacaaatggacaaggat
tattaccagctgcaagctgtattagaagctgaacgaagagacagaggtcatgattctgag
atgattggagacctgcaagctcgaaatacatctttacaagaggaggtgaagcatctcaaa
cataatcttgaaagagcggaaggagaaagaaaagaggctcaagacatgcttaatcattca
gaaaaggaaaagaataacttagaaatagatttaaactacaagcttaaatcattacagcaa
aggttagaacaagaggtaaatgaacataaagtaaccaaagctcgtttaactgacaaacat
caatctattgaagaggccaagtctgttgcaatgtgtgagatggaaaaaaagctgaaggaa
gagagggaagctcgagagaaggctgaaaatagggttgttcagattgagaagcagtgctcc
atgctagatgttgatctaaaacaatctcagcagaagctagagcatttgactgaaaataaa
gaaaggatggaggatgaagttaagaatctatccctgcaactggagcaggagtcaaataag
cgactgttgttacaaaatgaattgaagacccacgcatttgaggcagacaatttaaaaggt
ttagaaaagcagatgaaacaggaaataaatactttattggaagcaaagagattattagag
tttgaattagctcagcttacaaaacaatacagaggaaatgaaggacagatgcgggagcta
caagatcagcttgaagctgagcaatatttctcgacactttataaaactcaggtaaaggaa
cttaaggaagaaattgaagaaaaaaacagagaaaattcaaagaaaatacaggaactacaa
agtgaaaaagaaactcttgctactcagttggatctagcagaaacaaaagccgagtctgag
cagttggctcgagggcttctggaagaacagtattttgaattgacccaagaaagcaagaaa
gctgcttcaagaaatagacaagagattacagataaagagcacactgttagtcggctcgaa
gaaacgaacagtatgctaaccaaagatattgaattattaagaaaagaaaatgaagagcta
gctgataaaatgaagaaggcagaggaagaatataaactgaagaaggaggaggagatcaat
aatcttaaggctgcctttgaaaagaatatcaatacagaacgaacccttaaaacgcaggct
gttaacaagttggcagaaataatgaatcggaaagactttaaaattgatagaaagaaagct
aatacacaggatttgagaaagaaggaaaaggaaaatcgaaagctacaacttgaactcaac
caggaaagagagaaattcaaccagatggtagtgaaacatcagaaggaactgaatgacatg
caagcgcaattggtagaagaatgtacacataggaatgagcttcagatgcagttggctagc
aaagagagtgacattgagcaattgcgtgcgaaacttttggacctatcagattctacaagt
gttgctagttttcctagtgctgatgaaactgatggaaaccttccagaatcaagaattgaa
ggttggctttcaataccaaatagaggaaatatcaaaagatacggctggaagaaacagtat
gttgtggtaagcagcaaaaaaattttgttttataatgatgaacaagataaggaacaatcc
aatccatctatggtattggacattgataaattgtttcatgttcgtcctgtaacccaagga
gatgtgtacagagctgaaactgaagaaattcctaaaatattccagatactatacgcaaat
gaaggtgaatgtagaaaagatgtagagatggaaccagtacaacaagctgagaaaactaat
tttcaaaaccacaaaggtcatgagttcattcctaccctctaccactttcccgccaactgt
gaggcctgtgccaaacctctctggcatgtttttaagccaccccctgccctggaatgtcga
aggtgccacgttaagtgccacagagatcacttagataagaaagaggacttaatttctcca
tgtaaagtaagttatgatgtaacatcagcaagagatatgctgctactagcatgttctcag
gatgaacaaaaaaaatgggtaactcatttagtaaagaagattcctaagaatccaccatct
ggttttgttcgtgcatcgcctcgaacactttctacaagatccactgcaaatcagtctttc
cggaaagtggtcaaaaatacatctggaaaaactagttaa

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