Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112408602
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Entry
112408602 CDS
T08872
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
nasi
Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi00230
Purine metabolism
nasi00670
One carbon pool by folate
nasi01100
Metabolic pathways
nasi01523
Antifolate resistance
Module
nasi_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
nasi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
112408602 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
112408602 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112408602 (GART)
Enzymes [BR:
nasi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
112408602 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
112408602 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
112408602 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_3
CPSase_L_D2
ATP-grasp_2
DUF498
ATP-grasp_4
Dala_Dala_lig_C
LUD_dom
SNF5
Motif
Other DBs
NCBI-GeneID:
112408602
NCBI-ProteinID:
XP_024614060
UniProt:
A0A341CHQ3
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAARVLVIGNGGREHTLAWKLAQSNHVKQVLVTPGNAGTACSEKISNTDISISDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGSLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWRAFTKAEEACCFIMSADFPALVVKASGLAAGKGVVVAKSKEEACKAVQEIMQDKAF
GEAGETTVIEELLEGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPAP
QVSKDLLLEIKNTILQKTVDGMQQEGVPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWLDNRTAVTVVMASKGYPGDYTKGVEITGFPEA
QALGLEVFQAGTALKDGKVVTNGGRVLTVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
IGYHAIAFLQQPRGLTYKDSGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFNDPLLACGTDGVGTKLKIAQQCHKHETIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDPSTTEAVVAGIATACKKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAVERDQKLP
HLERITEGDAVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGGQALGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQTWRIPRIFSWLQQEG
HLSEEEMARTFNCGIGAALVVSKDLTQQILQDIQQHKEEAWAIGRVVACPEGSPRVKVKH
LIETMQINRSELENGTLKNHVSVQPKKARVAVLISGTGSNLQALIDSTREPSSSAHIVVV
ISNTAAVSGLDKAERAGIPTRVINHKLYKNRVAFDTTVDQVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDAGVTVTGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVETLSERVKLAEHKIFPSALQLVASGTVRLGENGKICWVKEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtaattggcaatggaggaagggaacatactctggcctggaaa
cttgcacagtctaatcatgtcaaacaagtgttagttaccccaggaaatgcaggcactgcc
tgctctgaaaagatttcgaacactgacatctcaatcagtgatcacactgcccttgcacag
ttctgcaaagatgagaaaattgaatttgtagttgttggaccagaggcacctctggctgct
ggaattgttgggagcctgacatctgcaggagtgcggtgctttggccctacagcagaagca
gctcagttagagtccagcaagagatttgccaaagagtttatggaccgacatggaatccca
actgcacagtggagagctttcaccaaagctgaagaagcctgctgcttcattatgagtgca
gacttccctgctttggttgtgaaggccagtggtcttgcagctgggaaaggggtagttgtc
gcaaagagcaaagaagaggcctgcaaagctgtacaggagattatgcaggataaagctttt
ggagaagctggagaaacaactgtcattgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggaaagactgtggcccctatgcccccagcacaggaccataagcga
ttgctggagggagatcagggccccaacacagggggaatgggagcctattgtccagcacct
caggtttctaaggatttgttgctagaaattaaaaatactattcttcagaagacagtggat
ggcatgcagcaggagggtgtgccatacacaggtatcctctatgctggtataatgctgacc
aaggatggcccaaaagttctggagtttaattgccgttttggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgacctttatgaagtgattcagtctaccttagatggcctg
ctctgcacatctctgcctgtttggcttgacaaccgcactgccgtaactgtggtcatggca
agtaaaggttatccaggagactacaccaaaggtgtagagataacagggtttcctgaggct
caagctttaggactagaggtgttccaagcaggcactgccctaaaagatggcaaagtggtg
actaacgggggtagggtccttacagtaacggccatccgggaaaatctcatctcagccctt
gaagaagccaagaaaggactagctgctataaagtttgagggggccatttataggaaggac
attggctatcatgccatagctttcctccagcagcccaggggcctgacttacaaggactct
ggggtagatattgcagctggaaatatgctggtcaagaaaattaagcctttagcaaaagcc
acctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagccggtttcaacgatcctcttctggcctgtggaacagacggcgttggaactaaactg
aagattgcccaacagtgccataaacatgaaaccattggtcaagatttggttgcgatgtgt
gtaaatgatattctggcgcaaggagcggagcccctctttttcctcgattacttttcctgt
ggaaaacttgaccccagtacaactgaagctgttgttgctggaatcgctacagcttgtaaa
aaagccggatgtgctctcctcggaggtgaaacggcagaaatgcctgacatgtaccctcct
ggagagtatgatctagccggttttgccgttggtgcagtggagcgggatcagaaactccct
cacctggaaagaatcactgaaggggacgctgttattggaatagcttcatctggtcttcac
agcaatggatttagccttgtgaggaaaattgtagcgaaatcttcccttcagtactcctct
ccagcacctgatggctgtggtggccaggccttaggtgatttacttctaactccaaccaga
atctacagccattcactgttacctgtcctgcgttcaggacatgttaaggcctttgcacat
attaccggtgggggattgctagaaaacatccccagagtcctgcctcagaaatttggggtg
gatttagatgcccagacctggaggatccccaggatcttctcgtggttacagcaggaagga
cacctctctgaagaagagatggccagaacatttaactgtgggattggggctgccctcgtg
gtatcaaaggatctgacacagcagattctgcaggatattcagcagcacaaggaagaagcc
tgggcgatcggcagagtggtcgcatgtcctgaaggttctcctcgtgtgaaagtcaagcat
ctgattgaaaccatgcagataaatagatcagagttggagaatggcaccctgaaaaatcat
gtctctgttcaaccaaaaaaggcaagagtagctgtcttaatatctgggacaggatcaaac
ctccaagctctcatagacagcactagggagccaagtagctctgcacacattgttgttgtg
atctccaacacagctgcagtgtctggcttagataaagcagaaagagccggaattcccacc
agagtaattaatcataaattatataaaaatcgtgtagcatttgacactacagtagaccaa
gtccttgaagagttctccacagacatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtcagaaaatggaatgggaaaatgctcaacatccacccatccttgctccct
tcgtttaagggttcaaatgcccatgaacaagtcctggatgccggggtcaccgtcactggg
tgcaccgtgcactttgtagctgaagatgtagatgctggacaaattattttacaagaagct
gttccggtgaagaggggtgacactgttgaaactctatctgaaagagtaaaattagcagaa
cataaaatatttccctcagccctccagctggtggccagtggaactgtacggcttggagaa
aatggcaagatctgttgggtcaaagaggaatga
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