Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112410245
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Entry
112410245 CDS
T08872
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
nasi
Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi04140
Autophagy - animal
nasi04141
Protein processing in endoplasmic reticulum
nasi04210
Apoptosis
nasi04932
Non-alcoholic fatty liver disease
nasi05010
Alzheimer disease
nasi05012
Parkinson disease
nasi05014
Amyotrophic lateral sclerosis
nasi05016
Huntington disease
nasi05017
Spinocerebellar ataxia
nasi05022
Pathways of neurodegeneration - multiple diseases
nasi05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nasi00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
112410245 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
112410245 (ERN1)
09143 Cell growth and death
04210 Apoptosis
112410245 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
112410245 (ERN1)
05012 Parkinson disease
112410245 (ERN1)
05014 Amyotrophic lateral sclerosis
112410245 (ERN1)
05016 Huntington disease
112410245 (ERN1)
05017 Spinocerebellar ataxia
112410245 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
112410245 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
112410245 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
112410245 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nasi01001
]
112410245 (ERN1)
Enzymes [BR:
nasi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
112410245 (ERN1)
Protein kinases [BR:
nasi01001
]
Serine/threonine kinases: Other
IRE family
112410245 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Pkinase_fungal
Kdo
APH
Tricorn_N
PQQ_2
Beta-prop_ACSF4
Motif
Other DBs
NCBI-GeneID:
112410245
NCBI-ProteinID:
XP_024616469
UniProt:
A0A341CP62
LinkDB
All DBs
Position
Unknown
AA seq
858 aa
AA seq
DB search
MGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNA
TYFDYAAALPEDDVEYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGL
RKVVHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLMPTLYVGKYSTSLYASP
SMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLHN
YWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVIDLVDQTSENAPTT
VSPDVEEKFAHVPPRPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSRRQQRQLQHQ
RFQKELEKIQLLQQQQLPFHPPGDVAAQDTDLLDSCGQYSESSATSSPSTSPRVSNHSLH
SSGSTSRAATGPFPEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAV
KRILPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDF
AHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPSAHGRIKAMISDFGLCKKL
AVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKS
LQRQANILLGACSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQ
LQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVR
DLLRAMRNKKHHYRELPEEGRETLGPLPNGFVRYFTSRFPHLLSHTYRAMELCRRERPFQ
PYYHEPPEPRPPVTPDAL
NT seq
2577 nt
NT seq
+upstream
nt +downstream
nt
atgggtaaaaagcaggacatctggtacgtcattgacctcctgaccggggagaaacagcag
actttgtcatcggcctttgcagatagtctctgcccatcaacctctcttctgtatcttggg
cgaacagagtacaccatcaccatgtacgacaccaaaacccgcgagctccggtggaacgcc
acctacttcgactacgcagctgcgctgcccgaggacgacgtggaatataaaatgtcccac
tttgtgtccaatggcgatgggctggtggtgaccgtggacagcgaatctggggacgtcctg
tggatccaaaactacgcttcccccgtggtggctttttacatctggcagcgggagggcctg
cggaaggtggtacacatcaacgtcgccgtggagaccctgcgctacctgaccttcatgtcg
ggggaggtggggcgcatcaccaagtggaagtacccgttccccaaggagacggaggccaag
agcaagctgatgcccaccctgtatgtggggaaatactctaccagtctctacgcttccccc
tcaatggtacacgagggggtcgccgttgtgccccgaggcagcacccttcctttgctggaa
ggaccccagaccgacggtgtcaccatcggggacaaaggggagtgtgtgatcacacccagc
acggacctgaagttcgaccctgggctcaaggggaagagcaagctcaactacctgcacaac
tactggctgctcatcggacaccacgagaccccactgtctgcatctaccaagatgctggag
cgattccccaacaatctgcccaaacaccgggaaaatgtgattcctgctgactcagagaaa
aagagctttgaggaggttatcgacctggttgaccagacttcagaaaacgcacccaccaca
gtttctccagatgtggaagagaagttcgctcatgtcccacccaggcccgaggcccccgtg
gactccatgctcaaggacatggccaccatcatcctgagcaccttcctgctcattggctgg
gtggccttcatcatcacctaccccctgagcagacgtcagcagcggcagctccagcaccag
cggtttcagaaggaactggagaagatccagctcctgcaacagcagcaactgcccttccac
ccacctggagacgtcgcagcccaggacaccgacctcctggactcgtgcggacagtactcg
gagagctcggccaccagcagccccagcacgtcccccagagtctccaaccactcgctccac
tccagcggctccacctccagggccgccaccggccccttcccggagcaggatgacgaggat
gaggaaaccagcatggtgatagttgggaaaatctcattctgtccgaaggacgtcctgggc
cacggagccgagggcacaattgtgtaccgtggcatgtttgacaaccgcgacgtggccgtc
aagaggatcctccccgagtgttttagtttcgcagaccgtgaggtccagctgctgcgagag
tcagacgagcacccaaacgtgatccgttacttctgcaccgagagggaccggcagttccag
tacatcgccatcgagctgtgcgcggccaccctgcaggagtacgtggagcagaaagacttt
gcccacctcggcctggagcccatcaccttgctgcagcagaccacctcgggcctggcccac
ctgcactccctcaacatcgttcacagagacctgaagccacacaacatcctcctctccatg
cccagcgcacacggcaggatcaaggccatgatctccgacttcggcctctgtaagaagctg
gcggtgggcagacacagcttcagccgccgctcaggggtgcccggcacagaaggctggatc
gccccggagatgctgagcgaagactgcaaggagaaccccacctacacggtggacatcttc
tctgcgggctgcgtcttttactacgtgatatctgagggcagccacccttttggcaagtcc
ctgcagcggcaggccaacatcctcctgggcgcctgcagcctggactgcctgcaccctgag
aagcacgaagacgttattgcccgggagttaatagagaagatgattgcaatggatcctcag
aagcgcccgtcagcgaagcatgtgctgaaacacccgttcttctggagcctagaaaagcag
ctccagttcttccaggacgtgagtgaccggatagagaaggagtccctagacggcccgata
gtgaagcagctggagcgcggcgggcgggctgtggtgaagatggactggagggagaacatc
actgtccccctccagacagatctgcgtaaattcagaacctataaaggcggctctgtccga
gatctcctccgggccatgagaaataagaagcaccactaccgggagctgcccgaggagggg
cgggagacgctaggcccccttcccaacggcttcgtgcgctacttcacctcgcgcttcccc
cacctcctctcccacacctaccgtgccatggagctgtgccgccgcgagaggcccttccag
ccctactaccacgagccccccgagccccggcccccagtgactccagacgccctctga
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