KEGG   Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112410494
Entry
112410494         CDS       T08872                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
nasi  Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi04120  Ubiquitin mediated proteolysis
nasi04380  Osteoclast differentiation
nasi04630  JAK-STAT signaling pathway
nasi04668  TNF signaling pathway
nasi04910  Insulin signaling pathway
nasi04917  Prolactin signaling pathway
nasi04920  Adipocytokine signaling pathway
nasi04930  Type II diabetes mellitus
nasi04931  Insulin resistance
nasi04932  Non-alcoholic fatty liver disease
nasi04935  Growth hormone synthesis, secretion and action
nasi05160  Hepatitis C
nasi05164  Influenza A
nasi05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:nasi00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    112410494 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    112410494 (SOCS3)
   04668 TNF signaling pathway
    112410494 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    112410494 (SOCS3)
   04920 Adipocytokine signaling pathway
    112410494 (SOCS3)
   04917 Prolactin signaling pathway
    112410494 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    112410494 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    112410494 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    112410494 (SOCS3)
   05164 Influenza A
    112410494 (SOCS3)
   05168 Herpes simplex virus 1 infection
    112410494 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    112410494 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    112410494 (SOCS3)
   04931 Insulin resistance
    112410494 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:nasi04121]
    112410494 (SOCS3)
Ubiquitin system [BR:nasi04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     112410494 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 112410494
NCBI-ProteinID: XP_024616945
UniProt: A0A341CRI7
LinkDB
Position
Unknown
AA seq 237 aa
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPSGAPSSSSPPAEPSSSPPAEPSSSPSSEVPEQPSAQPLPGSPPRRAYYIY
SGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 714 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacaccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ctgcaggagagcggcttctactggagcgccgtgacgggcggcgaggcgaacctactgctc
agcgccgagcccgccggcaccttcctcatacgcgacagctcggatcagcgccacttcttc
acgctcagcgtcaagacgcagtcggggaccaagaacctgcgcatccagtgcgaggggggc
agcttctcgctgcagagcgatcctcggagcacgcagccagtgccccgcttcgactgcgtg
ctcaagctggtgcatcactacatgccgccctccggcgccccctcctcctcctcgccccca
gctgaaccctcctcctcgcccccagctgaaccctcctcctcgccctcctccgaggtgccc
gagcagccgtcggcccagccgctcccggggagcccccccaggagagcctattacatctac
tcggggggcgagaagatccctctggtgttgagccggcccctctcctccaacgtggccact
ctccaacatctgtgtcggaagaccgttaacggccacctggactcctatgagaaagtcacc
cagctgcctgggcccattcgggagttcctggaccagtacgatgcccccctttag

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