Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112412959
Help
Entry
112412959 CDS
T08872
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
nasi
Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi01521
EGFR tyrosine kinase inhibitor resistance
nasi04151
PI3K-Akt signaling pathway
nasi04217
Necroptosis
nasi04380
Osteoclast differentiation
nasi04550
Signaling pathways regulating pluripotency of stem cells
nasi04620
Toll-like receptor signaling pathway
nasi04621
NOD-like receptor signaling pathway
nasi04630
JAK-STAT signaling pathway
nasi04658
Th1 and Th2 cell differentiation
nasi04659
Th17 cell differentiation
nasi05140
Leishmaniasis
nasi05145
Toxoplasmosis
nasi05152
Tuberculosis
nasi05160
Hepatitis C
nasi05161
Hepatitis B
nasi05162
Measles
nasi05163
Human cytomegalovirus infection
nasi05164
Influenza A
nasi05165
Human papillomavirus infection
nasi05166
Human T-cell leukemia virus 1 infection
nasi05167
Kaposi sarcoma-associated herpesvirus infection
nasi05168
Herpes simplex virus 1 infection
nasi05169
Epstein-Barr virus infection
nasi05171
Coronavirus disease - COVID-19
nasi05200
Pathways in cancer
nasi05203
Viral carcinogenesis
nasi05212
Pancreatic cancer
nasi05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
nasi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
112412959 (JAK1)
04151 PI3K-Akt signaling pathway
112412959 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
112412959 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
112412959 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
112412959 (JAK1)
04621 NOD-like receptor signaling pathway
112412959 (JAK1)
04658 Th1 and Th2 cell differentiation
112412959 (JAK1)
04659 Th17 cell differentiation
112412959 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
112412959 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112412959 (JAK1)
05203 Viral carcinogenesis
112412959 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
112412959 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
112412959 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
112412959 (JAK1)
05161 Hepatitis B
112412959 (JAK1)
05160 Hepatitis C
112412959 (JAK1)
05171 Coronavirus disease - COVID-19
112412959 (JAK1)
05164 Influenza A
112412959 (JAK1)
05162 Measles
112412959 (JAK1)
05168 Herpes simplex virus 1 infection
112412959 (JAK1)
05163 Human cytomegalovirus infection
112412959 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
112412959 (JAK1)
05169 Epstein-Barr virus infection
112412959 (JAK1)
05165 Human papillomavirus infection
112412959 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
112412959 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
112412959 (JAK1)
05140 Leishmaniasis
112412959 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112412959 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nasi01001
]
112412959 (JAK1)
Enzymes [BR:
nasi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
112412959 (JAK1)
Protein kinases [BR:
nasi01001
]
Non-receptor tyrosine kinases
JAK family [OT]
112412959 (JAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
ABC1
SH2
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
112412959
NCBI-ProteinID:
XP_024620523
UniProt:
A0A341D0I0
LinkDB
All DBs
Position
Unknown
AA seq
1153 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKTDVNLEAPEPGVEVLFYLSDREPLRLGGGEYTAEEL
CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNSYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
RFHPNDNGNILCYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR
EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKSELLGVQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK
RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIYSGT
LMDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL
LAREGTDSECGPFIKLSDPGIPVTVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI
MRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS
GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD
FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD
SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPEEVYQLMRKCWEFQPSIRTT
FQNLIEGFEALLK
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatttaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg
agctccaagaagactgacgtgaatctggaggcccctgagccaggggtggaagtgctcttc
tatctgtcggacagggagcccctccggttgggcggcggagagtacacagcggaggagctg
tgcatcagggcggcgcaggaatgctgtatatctcctctgtgtcacaacctctttgccctg
tatgatgagaacaccaagctctggtatgctccgaatcgcaccatcaccgtcgacgacaag
atgtcactccggctccactaccggatgaggttctatttcaccaactggcacgggaccaat
gataacgagcagtcagtatggcgacattctccaaagaagcagaagaatagctacgagaaa
aaaaaagttccagatgcaacccctctccttgacgccagctcattggagtatctgtttgct
cagggacagtatgatttggtcaaatgcctggctcccattcgagaccccaagacggagcag
gatgggcatgatattgagaacgagtgtctgggaatggccgtcctggccatctcccactat
gccatgatgaagaagatgcagttgccagaacttcccaaggacatcagctacaagcgatat
attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata
aataatgttttcaaggatttcctaaaggagtttaacaacaagaccatttgtgacagcagt
gtgtccacacatgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat
tatggtgctgaaatatttgagacttccatgctactgatttcatcagaaaatgagatgaat
cggttccatccgaatgataatggaaacattctctgctatgaagtgatggtgactggaaat
cttggaatccagtggaggcagaaaccaaatgttgttcctgttgaaaaggaaaaaaataaa
ctgaaacggaaaaaactggaaaataaacacaagaaggatgaggagaaaaataaaatccgg
gaagagtggaacaatttttcttacttccctgagatcactcacattgtaatcaaggagtct
gtggtcagcattaataagcaggacaacaaaaaaatggaactgaagctctcttcccacgag
gaggccttgtcctttgtgtccctcgtggacggctacttccggctcacagcagatgcccat
cattacctctgcaccgacgtggctcccccgttgatcgtccacaacatacagaatggctgt
cacggtccaatctgcacagaatatgccatcaataagttgcggcaagaaggaagcgaggag
ggaatgtacgtgctgcggtggagctgcaccgacttcgacaacatcctcatgaccgtcact
tgctttgaaaagtctgagttgctgggtgtccagaagcagttcaagaactttcagattgag
gtgcagaagggccgctacagcctgcatggctcagaccgaagcttccccagccttggagac
ctcatgagccacctgaagaagcagatcctgcgcacggacaacatcagctttgtgctgaag
cgctgctgccagcccaagccccgagaaatctccaatctgctggtggccaccaagaaagcc
caggagtggcagcctgtctaccccatgagccagctgagttttgatcggatcctcaagaaa
gatattatgcagggcgagcaccttgggagaggcacgcgaacacacatctactctgggacc
ctcatggattacaaggatgacgaaggaacttccgaagagaagagaataaaagtgatcctc
aaagtcttagaccccagccacagggacatttctctggccttctttgaggcagccagcatg
atgagacaggtctcccataaacacatcgtgtacctctatggcgtttgtgtccgagacgtg
gagaatatcatggtggaagagtttgtggagggagggcccctggatctcttcatgcaccgg
aaaagtgatgtcctcaccacaccctggaagttcaaagttgccaaacagctggccagcgcc
ctgagttacttggaggataaagatctggtccacggaaatgtgtgcactaaaaacctcctc
ctggcccgcgagggcactgacagcgagtgcggccccttcatcaagctcagtgaccccggc
atccccgtcactgtgctgtccaggcaagagtgcatagaacgaatcccatggatcgctcct
gagtgtgttgaagactccaagaacctgagtgtggccgctgacaagtggagctttggaacc
acgctctgggagatctgctacaatggcgagatccccttgaaagacaagacactgattgag
aaagagaggttctatgaaagccggtgcaggccagtgaccccgtcttgtaaggagctagct
gaccttatgacccgctgcatgaactacgaccccaaccagagacccttcttccgagccatc
atgagagacatcaataagctggaggagcagaatccagacatcgtatcagaaaaaaagcca
gcaactgaagtggatcccacacattttgaaaagcggttcttaaagaggatccgtgacttg
ggagagggccactttgggaaggtcgagctctgcaggtatgaccctgagggggacaataca
ggggagcaggtggccgtcaaatccctgaagcccgagagcggagggaaccacatagctgat
ctgaagaaggaaattgaaatcttaagaaacctttatcatgagaacattgtgaagtataaa
ggcatctgcacagaagacggaggaaacggtattaagctcatcatggaatttctgccttca
ggaagtcttaaggagtatcttccaaagaataagaacaaaattaacctcaaacagcagtta
aaatatgccgttcagatttgtaagggaatggactatttgggttctcggcaatacgttcac
cgtgacttagcagcaagaaatgtccttgttgagagtgaacaccaagtgaaaattggggac
tttggtctaaccaaagccattgaaactgataaggagtactacacagtcaaggacgatcgg
gacagccctgtgttttggtatgctccagaatgtttaattcagtgtaagttttatatcgcc
tctgatgtctggtcttttggagtaactctgcatgagctgcttacttactgtgattcagat
tccagtcccatggcgttgttcctgaaaatgataggcccaactcatggccagatgacagta
acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacctaactgtcca
gaagaggtttatcaacttatgagaaaatgctgggaattccaaccatccattcggacaacc
tttcagaaccttattgagggatttgaagcgcttctaaaataa
DBGET
integrated database retrieval system
