Nocardia brasiliensis: O3I_011705
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Entry
O3I_011705 CDS
T02270
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nbr
Nocardia brasiliensis
Pathway
nbr00300
Lysine biosynthesis
nbr00550
Peptidoglycan biosynthesis
nbr01100
Metabolic pathways
nbr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nbr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
O3I_011705
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
O3I_011705
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
O3I_011705
Enzymes [BR:
nbr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
O3I_011705
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AFU00302
UniProt:
K0ES64
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Position
2651937..2653442
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AA seq
501 aa
AA seq
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MIEMTLREIADVVGGTLHDVPDPEVRVTGSVEFDSRRIGSGDLFLALPGEHVDGHAYADA
AIAAGATAVLAARPVGVPAIVVAPNPGSVPSSSVALSGDSDGSGAAVLAALADLARASVQ
RLTAAGSLTVIGVTGSSGKTSTKDLLAAVLAPLGPVVAPPGSFNNELGHPWTALRANAET
RFLVLELSARGPGHIAALAEVAPPAIGVVLNVGTAHLGEFGSREAIAKTKGELVQALPPT
GLAVLNADDPQVAAMSARTTARVVRVGLSEGADIRATDVRLDDEARAGFILHTAAGSAAV
RLAVHGEHQVGNALSATAVALECGAELDAIAAALSGAHAASARRMDVRTTAGGVTVVNDS
YNANPDSVRAALKALVTMARSGETPRRSWAVLGEMGELGEESVLEHDRIGRLAVRLDVDR
LIVVGSGRPSRAMHQGAVMEGSWGEESILVPDIGAAIALLDDEIESGDVVLVKASKSVGL
WEVAEHLINTERDHDKAEALE
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atgatcgagatgacactgcgggagatcgcggacgtcgtgggcggcacgctgcacgacgta
cccgacccggaggtgcgggtgaccggttcggtcgaattcgattcgcgccgaatcggttcc
ggcgatctgttcctggccctgccgggggagcacgtggacggccacgcctacgcggacgcg
gcgatcgccgcgggcgcgaccgccgtgctcgccgcgcgcccggtgggagtgcccgccatc
gtggtcgcgccgaaccccggctcggtgccgtcgagttcggttgcgctgagcggggattcg
gatggatcgggcgccgcggtgctggccgcgctggccgacctggcgcgcgcgagcgtgcaa
cgcctcaccgcggcaggcagtctcacggtgatcggggtgaccgggtcgtccggcaagacc
tccaccaaggatctgctcgcggcggtgctcgcgccgctcggccccgtggtcgccccgccc
ggttcgttcaacaacgagctgggtcatccgtggacggcgttgcgcgccaacgccgagacc
cggttcctggtgctcgagctgtcggcccgcgggccggggcatatcgccgcgctcgccgag
gtcgcgccgccggcgatcggcgtcgtgctcaatgtcggcaccgcgcatctcggggaattc
ggcagccgcgaagccatcgcaaagaccaaaggcgaactggtgcaggcgcttccgccgacc
ggcttggccgtgctcaacgccgacgacccgcaggtcgccgccatgtccgcgcgcacgacc
gcgcgggtggtgcgcgtcgggctttccgagggcgccgatatccgggccaccgacgttcgc
ctcgacgacgaagcgcgcgccggtttcatcctgcacaccgccgcgggcagcgcggcggtg
cggctggcggtgcacggcgaacatcaggtcggcaacgcgctttccgcgaccgcggtcgcc
ctggaatgcggcgccgaactcgacgcgatcgctgccgcgctgtcgggcgcgcacgccgcg
tcggcccggcgcatggacgtgcgcaccaccgccggcggggtcaccgtcgtcaacgactcc
tacaacgccaaccccgactcggtgcgcgccgcgctcaaggcgctggtcaccatggcgcgg
tccggcgaaaccccgcggcgcagctgggcggtgctcggcgaaatgggtgaactgggcgag
gaatccgtgctcgagcacgaccggatcgggcggctcgcggtgcgcctggacgtggaccgg
ctcatcgtcgtcgggtccggaaggccgtcccgcgcgatgcaccagggagccgtgatggaa
ggctcatggggtgaggagtcgatcctggtgcccgatatcggcgccgccatcgcgttgctc
gacgacgaaatcgagtccggcgacgtggtgctcgtgaaagcgtcgaagtcggtgggcctc
tgggaggtcgccgaacacctgatcaacaccgagcgcgaccacgataaggcggaggctctc
gagtga
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