KEGG   Sciurus carolinensis (gray squirrel): 124962389
Entry
124962389         CDS       T08117                                 
Name
(RefSeq) GTPase NRas
  KO
K07828  GTPase NRas
Organism
ncar  Sciurus carolinensis (gray squirrel)
Pathway
ncar01521  EGFR tyrosine kinase inhibitor resistance
ncar01522  Endocrine resistance
ncar04010  MAPK signaling pathway
ncar04012  ErbB signaling pathway
ncar04014  Ras signaling pathway
ncar04015  Rap1 signaling pathway
ncar04062  Chemokine signaling pathway
ncar04068  FoxO signaling pathway
ncar04071  Sphingolipid signaling pathway
ncar04072  Phospholipase D signaling pathway
ncar04137  Mitophagy - animal
ncar04140  Autophagy - animal
ncar04150  mTOR signaling pathway
ncar04151  PI3K-Akt signaling pathway
ncar04210  Apoptosis
ncar04211  Longevity regulating pathway
ncar04213  Longevity regulating pathway - multiple species
ncar04218  Cellular senescence
ncar04360  Axon guidance
ncar04370  VEGF signaling pathway
ncar04371  Apelin signaling pathway
ncar04540  Gap junction
ncar04550  Signaling pathways regulating pluripotency of stem cells
ncar04625  C-type lectin receptor signaling pathway
ncar04650  Natural killer cell mediated cytotoxicity
ncar04660  T cell receptor signaling pathway
ncar04662  B cell receptor signaling pathway
ncar04664  Fc epsilon RI signaling pathway
ncar04714  Thermogenesis
ncar04720  Long-term potentiation
ncar04722  Neurotrophin signaling pathway
ncar04725  Cholinergic synapse
ncar04726  Serotonergic synapse
ncar04730  Long-term depression
ncar04810  Regulation of actin cytoskeleton
ncar04910  Insulin signaling pathway
ncar04912  GnRH signaling pathway
ncar04915  Estrogen signaling pathway
ncar04916  Melanogenesis
ncar04917  Prolactin signaling pathway
ncar04919  Thyroid hormone signaling pathway
ncar04921  Oxytocin signaling pathway
ncar04926  Relaxin signaling pathway
ncar04929  GnRH secretion
ncar04933  AGE-RAGE signaling pathway in diabetic complications
ncar04935  Growth hormone synthesis, secretion and action
ncar05010  Alzheimer disease
ncar05022  Pathways of neurodegeneration - multiple diseases
ncar05034  Alcoholism
ncar05160  Hepatitis C
ncar05161  Hepatitis B
ncar05163  Human cytomegalovirus infection
ncar05165  Human papillomavirus infection
ncar05166  Human T-cell leukemia virus 1 infection
ncar05167  Kaposi sarcoma-associated herpesvirus infection
ncar05170  Human immunodeficiency virus 1 infection
ncar05200  Pathways in cancer
ncar05203  Viral carcinogenesis
ncar05205  Proteoglycans in cancer
ncar05206  MicroRNAs in cancer
ncar05207  Chemical carcinogenesis - receptor activation
ncar05208  Chemical carcinogenesis - reactive oxygen species
ncar05210  Colorectal cancer
ncar05211  Renal cell carcinoma
ncar05213  Endometrial cancer
ncar05214  Glioma
ncar05215  Prostate cancer
ncar05216  Thyroid cancer
ncar05218  Melanoma
ncar05219  Bladder cancer
ncar05220  Chronic myeloid leukemia
ncar05221  Acute myeloid leukemia
ncar05223  Non-small cell lung cancer
ncar05224  Breast cancer
ncar05225  Hepatocellular carcinoma
ncar05226  Gastric cancer
ncar05230  Central carbon metabolism in cancer
ncar05231  Choline metabolism in cancer
ncar05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ncar05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ncar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    124962389
   04012 ErbB signaling pathway
    124962389
   04014 Ras signaling pathway
    124962389
   04015 Rap1 signaling pathway
    124962389
   04370 VEGF signaling pathway
    124962389
   04371 Apelin signaling pathway
    124962389
   04068 FoxO signaling pathway
    124962389
   04072 Phospholipase D signaling pathway
    124962389
   04071 Sphingolipid signaling pathway
    124962389
   04151 PI3K-Akt signaling pathway
    124962389
   04150 mTOR signaling pathway
    124962389
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    124962389
   04137 Mitophagy - animal
    124962389
  09143 Cell growth and death
   04210 Apoptosis
    124962389
   04218 Cellular senescence
    124962389
  09144 Cellular community - eukaryotes
   04540 Gap junction
    124962389
   04550 Signaling pathways regulating pluripotency of stem cells
    124962389
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    124962389
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    124962389
   04650 Natural killer cell mediated cytotoxicity
    124962389
   04660 T cell receptor signaling pathway
    124962389
   04662 B cell receptor signaling pathway
    124962389
   04664 Fc epsilon RI signaling pathway
    124962389
   04062 Chemokine signaling pathway
    124962389
  09152 Endocrine system
   04910 Insulin signaling pathway
    124962389
   04929 GnRH secretion
    124962389
   04912 GnRH signaling pathway
    124962389
   04915 Estrogen signaling pathway
    124962389
   04917 Prolactin signaling pathway
    124962389
   04921 Oxytocin signaling pathway
    124962389
   04926 Relaxin signaling pathway
    124962389
   04935 Growth hormone synthesis, secretion and action
    124962389
   04919 Thyroid hormone signaling pathway
    124962389
   04916 Melanogenesis
    124962389
  09156 Nervous system
   04725 Cholinergic synapse
    124962389
   04726 Serotonergic synapse
    124962389
   04720 Long-term potentiation
    124962389
   04730 Long-term depression
    124962389
   04722 Neurotrophin signaling pathway
    124962389
  09158 Development and regeneration
   04360 Axon guidance
    124962389
  09149 Aging
   04211 Longevity regulating pathway
    124962389
   04213 Longevity regulating pathway - multiple species
    124962389
  09159 Environmental adaptation
   04714 Thermogenesis
    124962389
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    124962389
   05206 MicroRNAs in cancer
    124962389
   05205 Proteoglycans in cancer
    124962389
   05207 Chemical carcinogenesis - receptor activation
    124962389
   05208 Chemical carcinogenesis - reactive oxygen species
    124962389
   05203 Viral carcinogenesis
    124962389
   05230 Central carbon metabolism in cancer
    124962389
   05231 Choline metabolism in cancer
    124962389
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    124962389
  09162 Cancer: specific types
   05210 Colorectal cancer
    124962389
   05225 Hepatocellular carcinoma
    124962389
   05226 Gastric cancer
    124962389
   05214 Glioma
    124962389
   05216 Thyroid cancer
    124962389
   05221 Acute myeloid leukemia
    124962389
   05220 Chronic myeloid leukemia
    124962389
   05218 Melanoma
    124962389
   05211 Renal cell carcinoma
    124962389
   05219 Bladder cancer
    124962389
   05215 Prostate cancer
    124962389
   05213 Endometrial cancer
    124962389
   05224 Breast cancer
    124962389
   05223 Non-small cell lung cancer
    124962389
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    124962389
   05170 Human immunodeficiency virus 1 infection
    124962389
   05161 Hepatitis B
    124962389
   05160 Hepatitis C
    124962389
   05163 Human cytomegalovirus infection
    124962389
   05167 Kaposi sarcoma-associated herpesvirus infection
    124962389
   05165 Human papillomavirus infection
    124962389
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    124962389
   05022 Pathways of neurodegeneration - multiple diseases
    124962389
  09165 Substance dependence
   05034 Alcoholism
    124962389
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    124962389
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    124962389
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    124962389
   01522 Endocrine resistance
    124962389
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ncar04131]
    124962389
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ncar04147]
    124962389
   04031 GTP-binding proteins [BR:ncar04031]
    124962389
Membrane trafficking [BR:ncar04131]
 Exocytosis
  Small GTPases and associated proteins
   Other small GTPases and associated proteins
    124962389
 Endocytosis
  Macropinocytosis
   Ras GTPases
    124962389
Exosome [BR:ncar04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   124962389
  Exosomal proteins of other body fluids (saliva and urine)
   124962389
  Exosomal proteins of breast cancer cells
   124962389
  Exosomal proteins of colorectal cancer cells
   124962389
GTP-binding proteins [BR:ncar04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    124962389
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N Septin Ldh_1_N
Other DBs
NCBI-GeneID: 124962389
NCBI-ProteinID: XP_047377658
LinkDB
Position
1:106959297..106969883
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL
PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQG
CMGLPCVVM
NT seq 570 nt   +upstreamnt  +downstreamnt
atgaccgagtacaaactggtggtggttggagcaggtggtgtgggtaaaagtgcactgaca
attcagctaatccagaaccattttgtggatgaatatgatcccaccatagaggattcttat
cgaaaacaggtggtaatagatggtgaaacctgtctattggacatactggatacagctgga
caagaggagtacagtgccatgagagaccagtatatgaggacaggcgaaggcttcctttgt
gtatttgccatcaataatagcaaatcatttgcagatattaatctctacagggagcagatt
aagcgagtaaaagactcagatgatgtacctatggtgctggtaggaaacaagtgtgatttg
ccaacaagaacagttgacacaaaacaagcccatgaactggccaagagttacgggataccg
ttcattgaaacctcagccaagaccagacagggtgttgaagatgctttctacacactggta
agagaaatacgccagtaccgaatgaaaaaactcaacagcagtgatgatgggactcaaggt
tgtatgggtttgccatgtgtggtgatgtaa

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