Sciurus carolinensis (gray squirrel): 124964042
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Entry
124964042 CDS
T08117
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
ncar
Sciurus carolinensis (gray squirrel)
Pathway
ncar05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
ncar00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
124964042
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
ncar03021
]
124964042
Enzymes [BR:
ncar01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
124964042
5.6.2.5 RNA 5'-3' helicase
124964042
Transcription machinery [BR:
ncar03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
124964042
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
nSTAND3
ResIII
SLFN-g3_helicase
AAA_16
NAT10_TcmA_helicase
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
124964042
NCBI-ProteinID:
XP_047379930
LinkDB
All DBs
Position
14:4158061..4235515
Genome browser
AA seq
2697 aa
AA seq
DB search
MKIVSHSQISQAVSTEDHISARFLPRYRMSTCCWCTPGGVSTIDFLKCYASRTLSSEFQT
ADEDLCYCLECVAEYHKARDELPFLHEVLWELETLRLINHFEKSMKAEIGDDDELYILDN
NGEAQPFDFTGQDFENKLRVPLLEILKYPYLLLHERVNELCVEALCRMEQANCSFQVFDK
HPGIYLFLVHPNEMVRRWAILTARNLGKVDRDDYYDLQEVLTCLFKVIELGLLESPDIYT
SSVLEKGKLILLPSHMYDTTNYKNYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILH
TMERQSDDDSVDPFWPALHCFMVILDRLGSKVWGQLIDPIEAFQTIINNGSYNREIKNIR
NSSIRTKLEPDSYLDDMVTCSQIVYNYNPEKAKKDSGWRSAICPDYCPNMYEEMETLANV
LQSDIGQDMRVHNSTFLWFIPFVQSLMDLKDLGVAYIVEVIHHLYSEVKDVLNQTDAVCD
KVTEFFLLILVSVIELHRNKKCLHLLWVSSQQWVEAVVKCAKLPTTAFARSTEKSSGNCS
KGTAMISSLSLHSVPSNSVQLACVLLIRSLLKEGYQLGQQTLCKRFLDKLNLFLRGNLSL
GWQLTSQETHELQTCLKQIIRNIKVKVPQCSTFVDLTPCKTPPAFFKEESEQIEKSKKDM
LCLENSSPTFSKEPMKIDTHQVQESILIKASSTVEDEGHEQNYIKDLNMEDNLSAESRLQ
QCSKSLFAERALNQSKVSKGVQKPVKESSHMPQSCPSRNGPDRACSRGIIKSTRSLTDSC
TDCLSKVTTSNEDFSLKDDVLGKTAKPKSKAQKEEICAKLSHVIKKQHRKSTLVSDAISL
EENLTASSMETFYSRKDAGVQKGDSFTHDLSLNPNGIPDDENGEQKSQNSLLLKKKHLKS
EELGMFSYENNCKVQDCYANDKDLVSFTEMTNTLVKKTSPFKDPVTILKSRDKDVNKSVD
LISSNLVREHVPGISPKSDTLTDSQVDRDLHKLSLIAQASVIKFPSDSTLKSTSQLQRRV
KDDKRFFSANQNNVVDTCHGQVIVISDSDDDDDERILGFEKHIEQDKVSIEKEHTRQHDS
IVTTTVEKKLIKEEKTNSLLQFEESDSQFFEFESPSEVFSVWQDHKVDNNSVQETEKSSC
VTYVADSTNNWGYGTEYASEEAIPRVVESVEEHLEPHSSSTSMEDLREIEVKKSKRKRFE
KPVLEDPLRPSSSVRNEDRSDVLNERDLTENDVQSTDVRTVTPSSSVQRATAVSLKKSPK
LRTYSKPIRRVPVSKTKKTHSDAKKGQNKSSHYLSCRTTPAVVPPKKFRQCPEPTSTVEK
LGLKKAPRKAFELSQRSLEYLVQLRDHGKTVGVVDTQKKTKLISPHTLSVKNNKKLQTSQ
GPQSPRQVRPKSQQNRQEFFDYESMDAPRAGTRKAQHSDILAPESERLDFKGTDALASSN
EKQLIKGMSSEPETKKAKYVSQVTDDACVLNQCNSGVLNGRLTTNEGMVSTSVDPLGGSD
LAVHRVEAAALKEVEPESNSDAEDDNLFLTQNDPEDMDLCSQMENGNDKLIELVHGKDTV
QIDEDSVSRPQLESLSVTKCKFKDGVENMKNQGECCSGPSETKADEDVFRKPGLPLSAAK
PLRPSTTKVFSSSSTSRIANLSRSLENASLPSALKNKSNGVQSILKVPQPASLVPQKPAG
DGKGLCNVLHSQAPNNSSKQGYKLPFGESKSFSVSSPVNILLSSQSISDTFVKEVLKWKY
EMFLNFDQCGPPASLCQSISRPVPVTFQDCGEYFNVFLPLMILNTFETVAQEWISSPNKE
NFFQLHLRKFPADYKKTWEFVVYLEECELAKQLHPKENDLVFLVPERVNGEKKDTERNCL
QDPQEYHCGYVHKFRRTSVVRNGKSECSLCIQTQDNLPANLNDLVKCIVISSLVTTQRKL
KAMSLLSGRNQLARAVLNPNPMDFCTKDLPTTTSERIIAYLRDFNEDQKKAIETAYAMVK
HSPSFAKICLIHGPPGTGKSKTIVGLLYRLLTENQRRGHSDENSNAKIKQNRVLVCAPSN
AAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMK
KDLPSHVQEMHRRKEYLDHQLDELSRQRALCRGGREIQRQELDEKIARVSKERQELASKI
KEVQGRPQKTQSIIILESHVICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVE
TLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFYKLLEEKVEQNVIGRLP
ILQLTIQYRMHPDICLFPSNYVYNRSLKTNRLTETNRCSSDWPFQPYLVFDVGDGSERRD
NDSYVNVQEIKLVMEIIRLIKDKRRDVTFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAE
VDTVDAFQGRQKDCVIVTCVRANAMQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLME
NQHWNHLIQDAQKRGAIIKTCDKNYRHDAMKILKLKPVLQRSLTHPPTIAPEVSRPQGGL
PSSKLDSEFAKTSFASSVYHTPSDSREAAVTSKDPERPPLQDRLRDPRLLRRLGADAKGK
FLRDPQPLSPQHPGATPPLGEPGFPITHQDLGSAVPLPAAKLPPQSNHTPPLQGEPPAVS
SDASTSKRKCDPEEGLSHRRETRAFSEGEQEKHSSVAYHTKRRLEKEESCSKKRKLS
NT seq
8094 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatcgtcagtcattcacagataagccaagcagtctcaactgaggatcacatctct
gcacgctttttgccaaggtacagaatgagcacatgttgttggtgtacaccaggtggtgtt
tccaccattgacttcctcaagtgctatgcatccaggaccctttccagtgaattccagaca
gctgatgaagacctctgctactgcttagaatgcgtagctgaataccacaaagcaagagat
gaattgccattcttgcatgaggtcttatgggaattagaaactttacgtctcataaaccac
tttgaaaaatccatgaaggcagaaattggagatgatgatgaattatatatactggacaac
aatggagaggcacagccatttgacttcactggccaagactttgaaaataagcttcgagtt
cctcttcttgaaatactgaaatacccttatctgcttctacatgagcgtgttaatgaatta
tgtgttgaagcactttgtcgaatggaacaagccaattgctcctttcaggtttttgacaaa
catccagggatctatttatttttggtccatcccaatgaaatggttcggcgttgggctatc
ttgactgcaagaaacttgggaaaagtggacagagatgattattatgacttacaggaggtt
ttaacttgcctcttcaaagtcatagagttggggcttttagaaagtccagacatctatact
tcttctgttcttgaaaagggtaaactgattcttctgccttcacacatgtatgatactacc
aactataaaaactactggttaggcatttgcatgttgctgaccattcttgaagagcaagcc
atggactcgctgttattgggctcagacaagcaaaacgactttatgcaatcaatccttcac
accatggagaggcaatcagatgatgatagtgtggatcctttctggccagccttacactgt
ttcatggtgatcctggatcgccttggatctaaggtatggggtcaactaattgatcccatt
gaggcatttcaaaccattatcaacaacgggagctacaatagggagataaaaaatatacgg
aacagctctataaggaccaagttagaaccagactcatatttggatgatatggtgacttgc
agccagattgtatacaattataatcctgaaaaggccaaaaaggattcagggtggagatca
gccatttgtccagattattgtcctaacatgtatgaagaaatggaaacattagccaatgta
ctgcagtcagacattggtcaagacatgcgtgtccacaacagcacatttctgtggttcata
ccttttgttcagtccctcatggatcttaaggacttgggtgtggcttacatagtagaggtt
attcatcatctgtactctgaagtcaaagatgtcctcaaccaaacagatgcagtgtgtgac
aaagtcactgaattttttcttctaattttggtgtcagtaattgaactgcatagaaataaa
aagtgtttgcatttgctgtgggttagctcccagcagtgggtggaagctgttgtaaaatgt
gccaagctccctaccactgcatttgcacggagtacagagaaatcatctggaaattgctcc
aaaggaacagcaatgatatcgtccctgtcattgcattcagtgccatctaactctgtacag
cttgcttgtgtgctactgataaggagtcttctgaaagaagggtaccaacttgggcagcag
actctttgtaaaaggttcctggataagctgaacttattccttcgaggaaatttgtctcta
ggttggcagttgactagtcaggaaacccatgagttacaaacatgtttaaaacaaattatt
agaaacataaaagtcaaagtacctcagtgtagcacttttgtggatctgactccatgtaaa
accccacctgcattttttaaagaagaaagtgaacagatagagaagtctaagaaggacatg
ctttgtctggaaaattccagcccaacattttctaaagagccgatgaaaattgacacacat
caagtgcaagagagtatattgattaaagccagtagtactgtagaagatgagggtcatgag
cagaattacataaaggacttgaatatggaagacaatctctcagctgagtcacgcttacag
cagtgcagcaaaagcctgtttgctgaaagagctctaaaccaaagtaaagtgagcaaaggg
gtacagaagcctgtgaaggagagctctcatatgccacagagctgtccttcaagaaatggg
ccagacagggcctgtagccgaggaatcatcaagtcaacacgttcactgactgattcctgc
actgattgtctgtcaaaggtaaccacatcaaatgaggatttctctttaaaggatgatgtt
cttggtaaaaccgcaaaaccaaaatctaaggcacagaaagaggaaatctgtgcaaagtta
tcacatgtcataaagaagcaacacaggaaaagtactttggtcagtgatgctatcagttta
gaggaaaatctgactgcatctagcatggagactttctattcaaggaaagatgcaggagtc
cagaaaggggatagcttcacacatgatctatctttaaaccctaatggtattccagatgat
gaaaatggagaacaaaaatcccaaaacagtttattactgaaaaagaaacacttaaagagc
gaagagttgggtatgttctcttatgaaaataattgcaaagtgcaggactgttacgctaat
gataaagatttggtctcatttacagaaatgaccaatactttggtgaagaaaacatctccc
tttaaagatcctgtgactatacttaaatcaagagataaggatgtgaataagagtgtggat
ctgatttcatctaacttggtaagagaacatgtccctggcatcagtcctaagtctgacact
ttaacagattctcaagtggacagagacctccacaaattatctttaatagctcaagccagt
gttattaagtttccttcagattcaactctaaaaagtacatcccagctgcagagaagagta
aaagacgataaaagatttttctcagctaaccaaaataatgttgtggatacatgccatgga
caagttattgttatttcagattctgatgatgatgatgatgagagaattcttggttttgaa
aaacacattgaacaggacaaagtatccattgagaaagaacataccaggcagcacgattca
atagttactactactgtagaaaagaagcttataaaggaagaaaaaacaaactcccttttg
cagtttgaggaatctgattctcagttttttgagtttgaaagtccatctgaagtgttttca
gtatggcaagatcataaagtggacaataattcagttcaggagactgagaaaagttcctgt
gtgacttacgtagctgacagcacaaataattggggttatggtacagaatatgcatctgaa
gaggctattcccagagtagtggagagtgtcgaagagcacctagagccacacagtagcagc
acttccatggaggatcttcgtgaaatcgaagttaaaaagtctaagagaaaacgatttgaa
aaacctgtgttggaagatcctctcagaccttcgtcatctgtcagaaatgaggaccggtct
gatgttcttaatgagcgagatcttactgaaaatgatgtacaaagtacagacgtaaggact
gtaactcccagttcaagtgttcagagggccacggcggtttcactaaaaaagtcaccaaag
cttcgaacttactcaaaacccattaggagagtcccagtttctaaaacaaagaaaacacat
tcagatgccaaaaaagggcagaataaaagttcacattacctaagttgtaggacaactcct
gctgtagttccaccaaagaaatttcgccagtgtcctgaaccaacttcaacagttgagaag
cttggtctgaaaaaagctcctcggaaggcctttgagttgtcccagcgatctttagagtat
ttagttcagttacgcgatcatggcaaaactgtcggagtagttgacacccaaaaaaagacc
aaattaatttctcctcacactctttctgttaaaaataataagaaactgcagacaagtcag
ggtcctcagtcaccaaggcaggtgagacctaaatcacaacaaaacagacaagaatttttt
gattatgaaagtatggatgctccaagggcagggacacgtaaagcacagcattctgacata
cttgcaccagagtctgagaggttggattttaaaggaaccgatgcacttgccagcagcaat
gaaaaacagttaataaaaggcatgtcttcagaaccagaaaccaaaaaagcaaagtatgtt
tcccaggtaacagatgatgcttgtgttttgaaccagtgcaattctggagtgctgaacgga
agactcacaacaaacgaaggaatggtttctacatcagtggaccctttaggtggaagtgac
cttgcagtgcatcgtgttgaagcagcagcgctgaaggaggtggagcctgagtccaacagc
gatgcagaggacgataacttatttttaacacagaatgatcctgaagatatggatttatgt
tcacaaatggagaatggcaatgataagctcattgagttggttcatggaaaagatacagtt
cagatagatgaagattctgtgagtcgacctcagttggaatctctgagtgtcacaaagtgt
aagttcaaagatggtgttgaaaacatgaaaaaccagggtgaatgctgctcaggaccctct
gaaaccaaagcagatgaagatgtgttccggaaacctggcttgcctctttctgcagccaaa
cctttaagaccttccaccactaaggtttttagttcaagtagtacttctcgcattgctaat
ctttccaggtctttggaaaatgcttcacttccatcagctctaaaaaataaatcaaatgga
gtacagtctattctgaaagtgccacagcctgcttccctggtccctcagaagccagcaggt
gacgggaagggtttgtgtaatgttcttcattctcaggctccaaataattccagcaagcaa
ggttacaaacttccatttggtgaaagcaaatctttttcagtttcttctccagtaaatatt
ctcttgtcatcacagtctatctccgacacctttgttaaagaggtcttaaaatggaaatat
gaaatgtttttgaactttgatcagtgtgggcccccagcaagtctttgtcagtccatctca
agacctgtacctgtcacatttcaagattgtggagagtattttaatgtgtttttacctttg
atgatattgaatacttttgaaacagtggcacaggaatggatcagctctccaaacaaagaa
aatttctttcagttgcatttacgaaaatttccagctgattataagaaaacctgggaattt
gtggtttatctggaagaatgtgaactggctaaacagcttcatccaaaggaaaatgatttg
gtgtttttagttcctgagagagtaaatggagagaaaaaagatacagagagaaactgcttg
caagatccccaggaatatcactgtggttatgttcataaatttcgccgcacttcagttgtt
cgtaatgggaaatctgagtgttccctttgcatccagactcaagataacttgccagccaac
ttaaatgaccttgtgaaatgcattgtaatcagttctctggtaactacacaaaggaaattg
aaagccatgtctctgttaagtggtcggaatcaactagccagagctgttctgaatccaaac
cccatggacttttgtaccaaagatttaccaactacgacgtctgagagaattattgcctac
ttaagagatttcaatgaagaccaaaagaaagcaatagaaactgcatatgccatggtgaaa
cactcaccatcatttgccaaaatctgtctgattcatggaccacctggcacaggaaaatca
aaaaccattgttggcctcctttaccgcttactgacagagaaccagaggagggggcattca
gatgaaaattccaatgccaaaatcaagcagaaccgtgtccttgtgtgtgcaccttccaat
gcagctgttgatgagctcatgaaaaagatcatcctcgagttcaaagaaaaatgcaaagat
aagaagaatcctttgggaaactgtggtgatattaatttagtacgattgggtccagaaaag
tctattaataatgaggtcctgaaattcagtctggacagccaagtcaaccacagaatgaaa
aaagacttaccttctcacgttcaggagatgcatagaagaaaggagtatctagatcatcag
ctagatgagctttcacgtcagcgagctctgtgccgaggtggacgggaaatacagaggcaa
gaattagatgaaaaaattgccagagtttcaaaagaaaggcaagaacttgcttctaaaatt
aaagaggttcaagggcgcccacagaaaacacagagcatcattatcttggagtcccatgtc
atctgctgcactctgagcacgagcgggggtctgctgctggagtctgctttccgagggcag
gggggtgttcccttcagttgtgtcattgttgatgaggccgggcagtcttgtgaagtggag
actctcacgccactcattcaccgctgcaacaagctcattctggtgggcgatcccaagcag
ctccctcccacggtcatttccatgaaagcacaggagtatggctacgaccagtcaatgatg
gctcgcttctacaaactgctggaggagaaggtagagcagaatgtgattggcagactgcca
attttacagctcactattcagtacaggatgcatccagatatatgtctcttcccttctaat
tatgtttataacagaagtttgaaaacaaataggctgactgaaaccaaccgatgttcatca
gactggccatttcaaccttatcttgtgtttgatgttggagatggttcagaaagacgggat
aatgactcatatgtaaatgttcaagaaataaaattggtgatggaaataattagacttatt
aaagacaaaagaagagatgtcacttttcgaaacattggcattataacccattacaaggct
cagaagacaatgattcagaaggatttggacaaagaatttgataggaaaggaccagcagaa
gtggatactgtggacgccttccagggtcgtcagaaggattgtgtcattgttacatgtgtc
agagcaaatgccatgcagggctcaattggattcctggccagtttgcagagattgaatgtc
accattacacgagccaagtacagcctcttcatcctcggacatctgaggactctgatggaa
aaccagcattggaatcacctgattcaggatgctcagaagcgtggtgccatcattaagacc
tgtgacaaaaactatagacatgatgcaatgaagattctgaaactcaagcctgtgctacag
agaagtctgacccacccacctaccatcgcccctgaggtgtcccgaccccaaggcggcttg
cctagcagcaagctagacagtgaatttgccaagacgtcttttgcatcttctgtataccac
acgccttctgactccagggaagctgctgttacttcaaaagaccctgaaaggccgcctctt
caggaccgacttcgggaccctcggctgctgaggagattgggtgctgacgccaaggggaag
ttcctaagagatccacaacccctgagcccccagcatcctggagcaacacctcccctggga
gagccaggctttcccatcactcaccaggacctgggcagtgcagtgccactgcctgctgct
aaactcccccctcagagcaaccacacacctcctttgcagggcgagcctccagccgtgagc
tcggatgcttccacgagtaaacgcaaatgtgacccggaagaggggctcagtcacaggaga
gagaccagggctttcagtgagggggaacaggagaagcatagctctgtcgcatatcacaca
aagaggagactggagaaagaggagagctgttccaagaagaggaagctttcatag
DBGET
integrated database retrieval system
