Sciurus carolinensis (gray squirrel): 124969605
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Entry
124969605 CDS
T08117
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit beta, mitochondrial
KO
K00162
pyruvate dehydrogenase E1 component subunit beta [EC:
1.2.4.1
]
Organism
ncar
Sciurus carolinensis (gray squirrel)
Pathway
ncar00010
Glycolysis / Gluconeogenesis
ncar00020
Citrate cycle (TCA cycle)
ncar00620
Pyruvate metabolism
ncar00785
Lipoic acid metabolism
ncar01100
Metabolic pathways
ncar01200
Carbon metabolism
ncar01210
2-Oxocarboxylic acid metabolism
ncar04066
HIF-1 signaling pathway
ncar04922
Glucagon signaling pathway
ncar05230
Central carbon metabolism in cancer
ncar05415
Diabetic cardiomyopathy
Module
ncar_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ncar00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
124969605
00020 Citrate cycle (TCA cycle)
124969605
00620 Pyruvate metabolism
124969605
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
124969605
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
124969605
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
124969605
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
124969605
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
124969605
Enzymes [BR:
ncar01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
124969605
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Motif
Pfam:
Transket_pyr
Transketolase_C
Motif
Other DBs
NCBI-GeneID:
124969605
NCBI-ProteinID:
XP_047388622
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Position
17:complement(57180842..57186529)
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AA seq
359 aa
AA seq
DB search
MAAVSGLVRRPLQQVSGLLRRRFHRTAPAALQMTVRDAINQGMDEELERDEKVFLLGEEV
AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
DQVINSAAKTYYMSGGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNS
EDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPAEAQSKDFLVPIGKAKVERQGTHITVV
SHSRPVGHCLEAATVLSKEGIECEVINMRTIRPMDIDTIEASVMKTNHLITVEGGWPQFG
VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSVPQVKDIIFAIKKTLNI
NT seq
1080 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggtatctgggctggtgcggagaccccttcagcaggtctccgggctgctgagg
aggcgctttcaccggaccgcgccggcggcgctgcagatgacagttcgtgatgctataaat
caaggtatggatgaggaactggaaagagatgagaaggtatttctgcttggggaagaagtt
gcccagtatgatggggcatacaaggttagccgaggcctgtggaagaagtacggagacaag
aggattatagatactcccatatctgagatgggctttgctggaattgctgttggtgcagct
atggctgggttgcggcccatttgtgaatttatgacctttaatttctccatgcaagccatt
gaccaggttataaactcagctgctaaaacctactatatgtcagggggcctccagcctgtg
cccatagtcttcagggggcccaatggtgcctcagcaggcgtagctgcccagcactcacag
tgctttgctgcgtggtatgggcactgcccaggcttgaaggtggtcagcccctggaattca
gaagatgcgaaaggactcatcaaatcagccattcgagataacaatccagtggtggtacta
gagaatgaattgatgtatggagttccttttgaatttcctgcagaagctcaatcaaaagat
tttctggttcctattggaaaagccaaagtagaaaggcaagggacacatataacggtggtt
tcccactcaagacctgtgggccactgcttagaagctgcaacggtgctatctaaagaggga
attgaatgtgaggtgataaatatgcgtaccatcagaccaatggacattgacaccatagaa
gccagtgtaatgaagacaaatcatctcataactgtggaaggaggctggccgcaatttgga
gtaggagctgaaatttgtgccaggatcatggaaggccctgcattcaacttcctggatgct
cctgctgttcgagtcactggtgctgacgtccctatgccttatgcaaagattctagaagac
aattctgtacctcaggtcaaggacatcatatttgcaataaagaaaacattaaatatctag
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