Sciurus carolinensis (gray squirrel): 124976781
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Entry
124976781 CDS
T08117
Name
(RefSeq) neuronal acetylcholine receptor subunit alpha-4 isoform X1
KO
K04806
nicotinic acetylcholine receptor alpha-4
Organism
ncar
Sciurus carolinensis (gray squirrel)
Pathway
ncar04080
Neuroactive ligand-receptor interaction
ncar04082
Neuroactive ligand signaling
ncar04725
Cholinergic synapse
ncar05033
Nicotine addiction
ncar05207
Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:
ncar00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
124976781
04082 Neuroactive ligand signaling
124976781
09150 Organismal Systems
09156 Nervous system
04725 Cholinergic synapse
124976781
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
124976781
09165 Substance dependence
05033 Nicotine addiction
124976781
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
ncar04040
]
124976781
Ion channels [BR:
ncar04040
]
Ligand-gated channels
Acetylcholine (nicotinic)
124976781
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Neur_chan_memb
Neur_chan_LBD
Motif
Other DBs
NCBI-GeneID:
124976781
NCBI-ProteinID:
XP_047395677
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All DBs
Position
2:747681..761742
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AA seq
626 aa
AA seq
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MELRGPRAPLLLLLLLLLGTGLLPVSSPAETRAHAEERLLKALFSGYNKWSRPVANISDV
VLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWRDYKLRWDPGDYENVTSIRIPSELIWRP
DIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGS
WTYDKAKIDLVSMHSRVDQLDFWESGEWVIVDAVGTYNTRKYECCAEVYPDITYAFVIRR
LPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLLITEIIPSTSL
VIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHSMPAWVRRVFLDIVPRLLFMKRP
SVVKDNCRRLIESMHKIASAPRFWPEPEGEPSILSGARSQGPSPTLSFCVPLDTPEPQPA
CKSPSNQVPALQPSEAEKASPCPSPAPCCPPNSTGAPGLTKARSLSVQHMSGPHEAEEGG
IRCRSRSIQYCVPRDRAASQADGQTAGSLASLKARSAELPPPDQLSPCKCTCKKEPSVVS
PVTVLKARSTAVPPRHLPLSPALTRAVEGVQYIADHLKAEDTDFSVREDWKYVAMVIDRI
FLWMFVIVCLLGTVGLFLPPWLAGMI
NT seq
1881 nt
NT seq
+upstream
nt +downstream
nt
atggagctccggggccccagggcgccgctgctgctgttgctgctcctgctcctggggacc
ggcctcctgcccgtgagcagtcctgcagagacccgggcccacgcggaggagcggctcctg
aaggcactcttctctggctacaacaagtggtcccgcccagtggccaacatctcagatgtg
gtcctggtccgcttcggcctgtccattgcccagctcattgacgtggacgagaagaaccag
atgatgaccacaaacgtgtgggtgaagcaggagtggcgtgactacaagctgcgctgggac
cccggggactacgagaacgtcacctccatccgcatcccctctgagctcatctggcggccg
gacatcgtcctctacaacaatgcggatggggactttgcggtcacccacctcaccaaggcc
cacctgttccacgacgggcgggtgcagtggacgcctccagccatctacaagagctcctgc
agcatcgacgtcaccttcttccccttcgaccagcagaactgcaccatgaagttcgggtcc
tggacctacgacaaggccaagatcgacctggtgagcatgcacagccgcgtagaccagctg
gacttctgggagagcggggagtgggtcatcgtggacgcggtgggcacctacaacacccgg
aagtacgagtgctgcgcggaggtctaccccgacatcacctacgccttcgtcatccgccgg
ctgccgctcttctacaccatcaacctcatcatcccctgcctgctcatctcctgcctcacc
gtgctggtcttctacctgccctccgactgtggcgagaaggtcacgctctgcatctccgtg
ctgctctcgctgaccgtcttcctgctgctcatcaccgagatcatcccgtccacctcgctg
gtcatcccgctcatcggcgagtacctgctcttcaccatgatcttcgtcacgctgtccatc
gtcatcaccgtcttcgtgctcaacgtgcaccaccgctccccccgcacccacagcatgccc
gcctgggtgcgcagggtcttcctggacatcgtgccccgcctgctcttcatgaagcggcca
tctgtggtcaaggacaactgccggcggctcatcgagtccatgcacaagatagccagtgcc
ccgcgattctggcctgagcccgagggggagcccagcatcctgagtggtgcgcgcagccag
ggaccgtcgcctactctgtccttctgcgtccccctggacacacctgaaccccagcctgcc
tgcaagtcaccctccaaccaggttcctgctctgcagccctcagaggccgagaaggccagt
ccctgcccctccccagccccctgttgcccacccaacagcacaggggccccagggctcacc
aaagccaggtccttgagcgtccagcacatgtccggcccccatgaagcagaggagggcggc
atccggtgccggtctcggagcatccagtactgcgttcctcgagaccgtgcagcctcccag
gctgatggccagacggctggctccctggcctccctgaaggcccgctcggctgagctccct
cccccagaccagctctctccatgcaaatgcacgtgcaagaaggagccctccgtggtgtcc
ccagtcaccgtgctcaaggcccgcagcactgcagtgccaccccggcacctgcccctgtca
ccagccctgactcgggcagttgagggtgtccagtacatcgctgaccacctgaaggcagaa
gacacggatttctcggtgagggaggactggaagtacgtggccatggtcatcgaccggatc
ttcctttggatgttcgtcatcgtctgcctgctgggcactgtgggcctcttcctgccacct
tggctggctggcatgatctag
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