KEGG   Sciurus carolinensis (gray squirrel): 124980599
Entry
124980599         CDS       T08117                                 
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
ncar  Sciurus carolinensis (gray squirrel)
Pathway
ncar04010  MAPK signaling pathway
ncar04015  Rap1 signaling pathway
ncar04218  Cellular senescence
ncar04620  Toll-like receptor signaling pathway
ncar04664  Fc epsilon RI signaling pathway
ncar04668  TNF signaling pathway
ncar04714  Thermogenesis
ncar04750  Inflammatory mediator regulation of TRP channels
ncar04912  GnRH signaling pathway
ncar04935  Growth hormone synthesis, secretion and action
ncar04936  Alcoholic liver disease
ncar05014  Amyotrophic lateral sclerosis
ncar05022  Pathways of neurodegeneration - multiple diseases
ncar05132  Salmonella infection
ncar05135  Yersinia infection
ncar05145  Toxoplasmosis
ncar05161  Hepatitis B
ncar05169  Epstein-Barr virus infection
ncar05170  Human immunodeficiency virus 1 infection
ncar05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ncar05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ncar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    124980599
   04015 Rap1 signaling pathway
    124980599
   04668 TNF signaling pathway
    124980599
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    124980599
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    124980599
   04664 Fc epsilon RI signaling pathway
    124980599
  09152 Endocrine system
   04912 GnRH signaling pathway
    124980599
   04935 Growth hormone synthesis, secretion and action
    124980599
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    124980599
  09159 Environmental adaptation
   04714 Thermogenesis
    124980599
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    124980599
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    124980599
   05161 Hepatitis B
    124980599
   05169 Epstein-Barr virus infection
    124980599
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    124980599
   05135 Yersinia infection
    124980599
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    124980599
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    124980599
   05022 Pathways of neurodegeneration - multiple diseases
    124980599
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    124980599
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    124980599
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ncar01001]
    124980599
Enzymes [BR:ncar01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     124980599
Protein kinases [BR:ncar01001]
 Serine/threonine kinases: STE group
  STE7 family
   124980599
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 Choline_kinase APH RIO1 DUF4344
Other DBs
NCBI-GeneID: 124980599
NCBI-ProteinID: XP_047402292
LinkDB
Position
3:complement(39799969..39825678)
AA seq 347 aa
MESPASSQPASMPQSKGKSKRRKDLRISCMTKPAVPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcgcctgcctcgagccagcctgccagcatgcctcagtcgaaaggaaaatccaag
agaaggaaggacttaaggatatcttgtatgactaagcccgctgtgcccaaccccacaccc
ccccggaacctggactcgcggaccttcatcaccattggagacagaaactttgaggtagag
gctgatgacctagtgaccatctcagagctgggccgtggagcctatggggtggtggagaag
gtgcggcatgcccagagtggcaccatcatggctgtgaagcggatccgggccacagtgaac
tcgcaggaacagaagcggctgcttatggacctggacatcaacatgcgcacagttgactgc
ttctacactgtcaccttctatggggctctcttcagagagggagatgtgtggatctgcatg
gagctgatggatacatccctagacaagttctaccggaaggtgctagataagaacatgacg
attccagaggacattctgggggagattgctgtgtctatcgtgcgggccctggagcacctg
catagcaagctgtctgtgatccacagagatgtgaagccatccaatgtcctcatcaacaag
gagggtcatgtgaagatgtgtgactttggcatcagtggctacttggtggactctgttgct
aagacaatggatgctggctgcaagccctacatggctcctgagagaatcaaccctgagctg
aaccagaagggctacaatgtcaagtctgatgtttggagtcttggcatcaccatgattgag
atggccattctacgattcccgtatgagtcctgggggaccccgttccagcagttgaagcag
gtggtggaggagccatccccccagctcccagctgaccgtttctcccccgagtttgtggac
ttcactgcccagtgcctgaggaagaatcctgcagagcgcatgagctacttggagctgatg
gagcaccctttcttcactttgcacaaaaccaagaagacggacattgctgccttcgtgaag
gagatcctgggagaagactcatag

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