Sciurus carolinensis (gray squirrel): 124981017
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Entry
124981017 CDS
T08117
Name
(RefSeq) LOW QUALITY PROTEIN: bifunctional purine biosynthesis protein ATIC-like
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
ncar
Sciurus carolinensis (gray squirrel)
Pathway
ncar00230
Purine metabolism
ncar00670
One carbon pool by folate
ncar01100
Metabolic pathways
ncar01523
Antifolate resistance
Module
ncar_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ncar00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
124981017
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
124981017
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
124981017
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ncar04147
]
124981017
Enzymes [BR:
ncar01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
124981017
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
124981017
Exosome [BR:
ncar04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
124981017
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Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
124981017
NCBI-ProteinID:
XP_047403128
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Position
3:161437257..161470965
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AA seq
592 aa
AA seq
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MAPGQLALFSVSDKTGLVEFARNLTSLGLNLVASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPQDNADMARLDFNLIRVVACNLYPFVKTVSSPDVTVEEA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVAVSTEMQRSDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRKQYSKGISQMPLRYGMNPHQTPAQLYTLKPRLPITVLNGAPGFINL
CDALNAWQLVKELREALDIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYNTLTPIS
TAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIVAPGYEEEALKILCKKKNG
NYCVLQMDQSYKPDEDEVRTLFGLRLSQKRNNGVIDRSLFSNVVTKNKEVPESALRDLIV
ATVAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANSWWLRHHPRVLSMKFKT
GVKRAEISNAIDQYVTGTIGEGEDLRKWQALFEEVPELLTEAEKKEWVDKLSEVSVSSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTDLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcccccggccagctcgccttgttcagtgtctctgacaaaactggccttgtggaattt
gccagaaacctaacgtctcttggtttgaatctggtcgcttccggagggactgcaaaagct
ctcagggatgctggcctggcggtcagagatgtctctgagctaactggatttcctgaaatg
ttaggggggcgagtgaaaaccttgcatcctgcagtccacgctggaatcctggctcgtaat
atcccgcaagataatgctgacatggccagacttgattttaatcttataagagttgttgcc
tgcaatttgtatccctttgtgaagacagtttcttctccagatgtaactgttgaggaggct
gttgagcaaattgatattggtggagtgaccttactgagagctgcagccaaaaaccatgcc
cgagtgacagttgtgtgtgaaccagaggactatgtggcagtgtccacagagatgcaaaga
tctgatagtaaagacacctccttggagacgaggcgccagttggccttgaaggcattcact
cacacagcacaatatgatgaagcaatttcagattacttcaggaagcagtacagtaaagga
atatctcagatgcccttgcggtatggaatgaaccctcatcagactcctgcccagctctac
acactgaagccccggcttcccatcacagttctcaatggagcgcctggattcataaacctg
tgcgatgctttgaatgcgtggcagctggtgaaggaactgagggaggctttagacattcca
gctgcggcctctttcaaacacgtcagcccagcaggagctgcagttggaattccactcagt
gaagatgaggccaaagtttgcatggtctatgacctctataacacccttacaccaatatca
actgcatatgcaagagcaagaggggctgataggatgtcttcttttggtgattttgttgca
ttatctgatgtttgtgatgtcccaactgcgaaaattatctccagagaagtgtctgatggt
attgttgccccaggatatgaagaagaagccttgaaaatactttgtaaaaaaaaaaatggg
aactactgtgttcttcagatggatcaatcttacaaaccagatgaggatgaagttcgaact
ctctttggtcttcgcttaagccagaagagaaataatggtgtcattgacaggtcattattt
agcaatgttgttaccaagaataaagaggttccggagtctgccctcagagacctcatcgtg
gccaccgttgctgtcaagtacactcagtctaactctgtgtgctatgccaagaacggacag
gttattggcattggagcaggacagcagtctcgaatacactgtacacgcctcgcaggggat
aaagcaaactcttggtggcttagacatcacccacgagtgctctcgatgaagtttaaaaca
ggggtaaagagagcagaaatctccaatgccatcgatcagtacgtgactggcactattggt
gagggtgaagatttgcggaagtggcaggcactatttgaggaagtccctgagttgttaact
gaggctgagaagaaggagtgggtggacaaactgagtgaggtttccgtcagctccgatgcc
ttctttcctttcagggataatgtagacagagctaaaaggagcggcgtggcgtacattgca
gccccttctggttctgctgctgacaaggttgtgattgaggcttgcgatgaactgggaatc
atcttggctcacacggatcttcggctcttccaccactaa
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