Sciurus carolinensis (gray squirrel): 124981155
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Entry
124981155 CDS
T08117
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
ncar
Sciurus carolinensis (gray squirrel)
Pathway
ncar01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
ncar00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
124981155
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ncar03032
]
124981155
03036 Chromosome and associated proteins [BR:
ncar03036
]
124981155
Enzymes [BR:
ncar01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
124981155
DNA replication proteins [BR:
ncar03032
]
Eukaryotic type
DNA Topoisomerases
124981155
Chromosome and associated proteins [BR:
ncar03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
124981155
Centrosome formation proteins
Centriole proteins
124981155
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Motif
Other DBs
NCBI-GeneID:
124981155
NCBI-ProteinID:
XP_047403295
LinkDB
All DBs
Position
3:22095785..22121720
Genome browser
AA seq
1533 aa
AA seq
DB search
MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDIGMNYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFSGEDFTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDVAGSTKDVKVFLNGIKLPVKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEIAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQVDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVINGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFYELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKGDSVTDSGPTFNYLLDMPLWYLTKEK
KDELCKQRNEKEQELNTLKRKSPSDLWKEDLAAFIEELEAVEAKEKQDEQVGLPGKGGKA
KGKKIQVTEVLPSPRGKRVIPRVTIEMKAEAEKKIKKKIKSENTEGTFKEDGVELENLKQ
RLEKKQKKEPGTKAKKQTTLPFKPIKKGKKRNPWSDSESDMSSTESNFDVPPRETEPRRA
ATKTKFTMDLDSDEDFSDFDEKTEDEDFVPSDASPPKAKTPPKHTKKELKPQKSTTSVTD
LEADDAKDSVPSSSSPPAADLLTETEIMKPSSKKTVTVKKTAAKSQSSTSTNATKKKAAP
KGTKKDPDLNSDVSQKPDPAKTKNRRKRKPSTSDDSDSNFEKIISKAGTSKKPRGESDDF
HLDLDSTVAPRAKSGRAKKPIKYLEESDEDDLF
NT seq
4602 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccactgcagcctgtaaacgaaaacatgcaagtgaacaaaattaagaaa
aatgaagatgctaagaaaagactatctattgaaagaatctatcaaaagaaaacgcaattg
gaacatatattgctccgcccagacacctacattggctctgtggaattagtgacccagcaa
atgtgggtttacgatgaagatattggcatgaactatagggaagtcacttttgttcctggt
ttgtacaaaatctttgatgaaattctagttaatgctgcagacaacaaacaaagggatccc
aaaatgtcttgtattagagtcactattgacccagaaaacaatttaattagtatatggaat
aatggaaaaggaattcctgttgttgaacacaaagttgaaaagatgtatgtcccagctctt
atatttggacagctcttaacttctagtaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggctatggagccaaattatgtaatatattcagcaccaaatttactgtggaa
acagccagtagagaatacaagaaaatgttcaaacagacatggatggataacatggggcga
gctggtgagatggaactcaagccttttagtggagaagattttacatgtatcaccttccag
cctgatttgtctaagtttaaaatgcaaagcctagacaaagatattgttgcactgatggtt
agaagagcatatgatgttgctggatccactaaagatgtcaaagtctttcttaatggaatt
aagttgccagtaaaaggattccgcagttatgtggatatgtatttgaaggataagttagat
gaaactggcaacccattgaaagtaatacatgaacaagtaaaccacagatgggaggtgtgt
ctaacaatgagtgaaaaaggctttcagcaaattagtttcgtcaatagcattgctacttcc
aagggtggcagacatgttgattatgtagctgatcagattgtgactaaacttgttgatgta
gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaatccaacctttgactctcagaccaaagaaaat
atgactttgcaagccaagagctttggatcaacatgccaattaagtgaaaaattcatcaaa
gctgcaattggctgtggtattgtagaaagcatactaaactgggtaaaatttaaggcccaa
gtccagttaaacaagaagtgttcagctgtaaaacataacagaatcaagggaattccaaaa
cttgatgatgctaatgatgcaggaagtcgaaactccactgagtgtacacttatcctgact
gagggagactcagccaaaactttggctgtttcaggccttggtgtggttgggagagacaaa
tatggtgttttccctcttagaggtaaaatactcaatgtccgagaagcttctcataaacag
atcatggaaaatgctgaaattaacaatatcatcaaaattgtgggtcttcagtataagaaa
aactatgaagatgaagattcattgaagactcttcgttatgggaagataatgattatgaca
gatcaggaccaagatggttcccatatcaaaggcttgctgattaattttatccatcacaac
tggccctctcttctgcgacatcgttttctggaggagtttatcactcccattgtaaaggta
tctaaaaacaagcaagaaatagcattctatagccttcctgaatttgaagaatggaaaagt
tctactccaaaccataaaaaatggaaagtcaagtattacaaaggtttgggcaccagtaca
tcaaaagaagctaaggaatactttgcagatatgaaaagacatcgtattcagtttaaatat
tctgggcccgaagatgatgctgcaatcagcctagcctttagcaaaaagcaggtagatgat
cgaaaggaatggttaactcacttcatggaggatagaagacagcgaaagttacttggcctt
cctgaggattatttgtatgggcaaactaccacttacctgacatacaatgactttataaac
aaggaacttatcctgttctcaaattctgataatgagagatctatcccatctatggtggat
ggtttgaaacctggtcagagaaaggttttgtttacttgtttcaaacgaaatgataagcgg
gaggtgaaggttgcccagttagctgggtcagtggcagaaatgtcctcttaccatcatggt
gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat
ctgaacctcttgcaacccattggtcaatttggtacccggctacatggtggcaaggattct
gctagccctcgatacatcttcacaatgctcagccctttggctaggttgttatttccacca
aaagatgatcatacgttgaagttcttatatgatgacaaccaacgagttgaacctgaatgg
tacattcctattatacccatggtcctgataaatggtgctgaaggaattggtactggatgg
tcctgcaaaattcccaactttgatgttcgtgaagttgtaaataacatcaggcgtttgatg
gatggagaagaacctttgccaatgcttccaagttacaagaacttcaaaggtactattgaa
gagctggctccaaatcaatatgtgattaatggtgaagtagctattcttaattccacaacc
attgaaatctcagaacttcccatcagaacgtggacccaaacatataaagaacaggtccta
gaacccatgctaaatggcactgagaagacaccccctctcataacagactatcgggaatac
cacacagataccactgtgaagtttgttgtaaagatgactgaggaaaaattggcagaggca
gagagagttgggctacacaaagtcttcaaactccaaactagtctcacctgcaattctatg
gtactttttgaccatgtaggctgtttaaagaaatatgacacagtgttggatattctaaga
gacttctatgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg
cttggtgctgaatctgctaaactgaataatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataagcctaaaaaagagttaattaaagttctaattcagaga
ggatatgattctgatcctgtgaaggcctggaaagaagcccagcaaaaggttccagatgaa
gaagagaacgaagagagtgacaatgaaaaggagacagaaaagggtgactctgtaacagat
tctgggccaaccttcaactaccttcttgatatgcccctttggtatctaaccaaggaaaag
aaagatgaactgtgcaaacaaagaaatgaaaaggagcaagagctgaacacattaaagaga
aagagtccatcagatttgtggaaagaagatttagctgcttttattgaggaattggaggct
gttgaagccaaggaaaaacaagatgaacaagtaggtctaccagggaaaggtggaaaggca
aagggaaaaaaaatacaagtgactgaagttttgccttctccacgaggaaaaagagtcatt
ccccgagttaccatagagatgaaagcagaggcagaaaagaaaattaaaaagaaaattaag
agtgaaaatactgagggaacctttaaggaggatggtgtagaactagaaaacctaaaacaa
agactggagaagaaacagaaaaaagaaccaggcaccaaggcaaagaaacagactacattg
ccatttaaacctatcaaaaaaggaaaaaagagaaacccctggtctgattctgaatcggat
atgagcagtactgaaagtaattttgatgtccctccacgagaaacagagccacggagagct
gcaacaaaaaccaaattcacaatggatttggattcagatgaagatttctcagattttgat
gaaaaaactgaagatgaagatttcgtcccatcagatgctagcccacctaaggccaaaact
cccccaaaacatactaaaaaagaactgaagccacagaaaagtaccacgtctgtgactgac
cttgaggctgacgatgctaaagacagtgtaccatcttcttcaagccctcctgcagccgat
ctcctaactgaaactgaaattatgaagccgtcttcaaaaaagactgtgacagtgaagaag
acagcagcaaaaagtcagtcttccacctccactaatgctaccaagaaaaaggctgcacca
aaaggaacgaagaaggatccagacttgaattctgatgtttctcaaaagcctgatcctgcc
aaaaccaagaatcgacgcaaaaggaagccatccacttctgatgattctgactctaatttt
gagaaaatcatttctaaagcaggcacaagcaagaagccccggggggagagcgatgacttt
catctggacttggactcaactgtggctcctcgggcaaaatctggacgggcaaagaaacct
ataaagtacctggaagagtcagatgaagatgatctgttttaa
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