KEGG   Sciurus carolinensis (gray squirrel): 124990426
Entry
124990426         CDS       T08117                                 
Name
(RefSeq) hepatocyte growth factor receptor
  KO
K05099  proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
Organism
ncar  Sciurus carolinensis (gray squirrel)
Pathway
ncar01521  EGFR tyrosine kinase inhibitor resistance
ncar04010  MAPK signaling pathway
ncar04014  Ras signaling pathway
ncar04015  Rap1 signaling pathway
ncar04020  Calcium signaling pathway
ncar04151  PI3K-Akt signaling pathway
ncar04360  Axon guidance
ncar04510  Focal adhesion
ncar04520  Adherens junction
ncar05100  Bacterial invasion of epithelial cells
ncar05144  Malaria
ncar05200  Pathways in cancer
ncar05202  Transcriptional misregulation in cancer
ncar05205  Proteoglycans in cancer
ncar05206  MicroRNAs in cancer
ncar05208  Chemical carcinogenesis - reactive oxygen species
ncar05211  Renal cell carcinoma
ncar05218  Melanoma
ncar05223  Non-small cell lung cancer
ncar05225  Hepatocellular carcinoma
ncar05226  Gastric cancer
ncar05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ncar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    124990426
   04014 Ras signaling pathway
    124990426
   04015 Rap1 signaling pathway
    124990426
   04020 Calcium signaling pathway
    124990426
   04151 PI3K-Akt signaling pathway
    124990426
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    124990426
   04520 Adherens junction
    124990426
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    124990426
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    124990426
   05202 Transcriptional misregulation in cancer
    124990426
   05206 MicroRNAs in cancer
    124990426
   05205 Proteoglycans in cancer
    124990426
   05208 Chemical carcinogenesis - reactive oxygen species
    124990426
   05230 Central carbon metabolism in cancer
    124990426
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    124990426
   05226 Gastric cancer
    124990426
   05218 Melanoma
    124990426
   05211 Renal cell carcinoma
    124990426
   05223 Non-small cell lung cancer
    124990426
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    124990426
  09174 Infectious disease: parasitic
   05144 Malaria
    124990426
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    124990426
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ncar01001]
    124990426
Enzymes [BR:ncar01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     124990426
Protein kinases [BR:ncar01001]
 Receptor tyrosine kinases (RTK)
  MET family
   124990426
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr TIG Pkinase Sema PSI Kinase-like Pkinase_fungal Linker_histone
Other DBs
NCBI-GeneID: 124990426
NCBI-ProteinID: XP_047416437
LinkDB
Position
8:complement(36148070..36258672)
AA seq 1380 aa
MKVPAVLAPGLLVLLFTWVQRSDGECKEALAKSEMNVNVNYQLPNFTAETPIQNVVLHEH
HIYLGATNYIYVLNEKDLQKVAEYKTGPVLEHPDCLPCQDCSSKANLSGGVWKDNVNMAL
LLDTYYDDQLISCGSVNRGTCQRHVLPPHNAADIQREVHCMFSPQADEEPGQCPDCVVSA
LGAKVLLSEKERFVNFFVGNTINSSYLPDHSLHSISVRRLKETQDGFKFLTDQSYIDVLP
EFRDSYPIKYVHAFESNHFIYFLTVQRETLNAQTFHTRIIRFCSMDSGLHSYMEMPLECI
LTEKRRKRSTREEVFNILQAAYVSKPGAHLAKQIGANLNDDILYGVFAQSKPDSAEPMNR
SAVCAFPIKYVNEYFNKIVNKNNVRCLQHFYGPNHEHCFNRMLLRNSSGCEVRSDEYRTE
FTTPLPRIDLFMGQFNQVLLTSISTFIKGNLTIANLGTSEGRFMQVVVSRTVSSTPHVNF
RLDSHPVSPEVIVEHPLNQNGYTLVITGKKITKIPLNGLGCGHFQSCSQCLSAPPFVQCG
WCHDQCVRSDECPSGTQEICLPTVYKVFPTSAPLEGGTMLTICGWDFGFRKNNKFDLKKT
KVLLGNESCTLTLSESTKNTLKCTVGPAMNEHFNMSIIISNSRGTAQYSTFSYVDPVITR
ISPSYGPKAGGTLLTLTGKYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISAEFP
VKLKIDLANRETSSFSYREDPVVYEIHPTKSFISGGSTITGVGKNLNSVSVPRLVINVHE
AGRNYTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKALFMLDGILSKYFDLIYVHNPVF
KPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIRSHSEAILCTVPNDLL
KLNSELNIEWKQAVTSTVLGKVIVQPDQNFTGLVVGVVSISIILLLLFGLFLWLKKRKQI
KDLGSDLVRYDARVHTPHLDRLVSARSVSPTAEMVSNESVDYRATFPEDQFPNSSQNGSC
RQGQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFN
EVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLS
LLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFV
HRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFT
TKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWH
PKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNVDGVVDT
NT seq 4143 nt   +upstreamnt  +downstreamnt
atgaaggtccccgctgtgcttgcacctggcctccttgtgctgctgttcacctgggtgcag
aggagtgatggggagtgtaaagaggcactagcgaagtccgagatgaatgtgaacgtgaac
tatcagcttcccaacttcaccgcagaaacgcccatccagaatgtcgttctacatgagcat
cacatttacctcggtgccactaactacatttatgtcttaaatgagaaggaccttcagaag
gtggcggagtacaagactgggcctgtgctggaacacccggattgtcttccatgtcaggac
tgcagcagcaaagccaatttgtcagggggtgtttggaaagataacgtcaacatggccctg
ctcttggacacatactatgatgaccaactcattagctgcggcagtgtcaaccgagggacc
tgccagcgacacgtccttccaccccataatgctgctgacatacagcgggaggtccactgc
atgttctccccacaagcagatgaagagccggggcagtgtcctgactgtgtggtgagcgcc
ctgggagccaaagtcctcctctctgaaaaggagaggttcgtcaacttctttgtgggcaat
acaataaattcttcttaccttccagatcattcgttgcattcaatatcagtgagaaggcta
aaggaaacacaagacggctttaagttcttgacagatcagtcctatatagatgttttgcct
gagttccgagattcttatcccattaagtatgtccacgccttcgaaagcaatcattttatt
tactttctgacggtccagagggaaactctgaatgctcagacttttcataccagaataatc
aggttctgttccatggactctggattgcattcctacatggaaatgcctctggagtgtatt
ctcacggaaaagagaagaaagagatccacgagggaggaggtatttaatatccttcaagct
gcatatgtcagtaagcctggggcccatcttgctaagcaaataggcgccaacctaaatgat
gacattctctatggggtgttcgcacagagtaagccagattctgctgaaccaatgaatcga
tcggctgtctgtgccttccctatcaaatatgtcaatgaatacttcaacaagatcgtcaac
aaaaacaacgtgagatgtctccagcatttttatggacccaatcatgagcactgttttaat
aggatgctcctgagaaattcatcaggctgtgaagtgcgcagtgatgaatatcgaacagag
tttaccacacctttgccacgcattgacttattcatgggccaattcaaccaagtgctctta
acatctatatctaccttcattaaaggaaatctcaccattgctaatcttggaacatcagag
ggtcgcttcatgcaggttgtggtttctcgaacagtatcatccaccccccatgtgaatttt
cgcctggattcccaccctgtgtccccagaagtgattgtggagcacccattaaaccaaaat
ggctataccctggttatcactgggaaaaagatcaccaaaatcccactaaatggcttgggc
tgtggacatttccagtcctgcagtcagtgtctctctgcccctccttttgtgcagtgtggt
tggtgccacgatcaatgtgtgcgatcagacgaatgtcccagtgggactcaagagatctgt
ctgcctacagtctataaggtttttccaactagtgcaccccttgaaggagggacaatgctg
accatatgtggctgggactttggattcaggaagaacaacaaatttgatttaaaaaaaacc
aaagttctccttggaaatgagagctgcaccttgaccttgagtgagagcacaaaaaatacg
ctgaaatgcacagttggtcctgcaatgaatgaacatttcaatatgtccataattatttca
aacagtcggggcacagcacaatatagtacattttcttacgtagatcctgtgataaccagg
atttctccaagttatggtcccaaagctggaggcactttactcactttaactggaaagtat
ctaaacagtgggaattctagacacatttcaattggtggaaaaacatgtactttaaaaagt
gtgtcaaatagtattctcgaatgttataccccagcccaaaccatttcagctgagtttccg
gtgaaattgaaaattgacttagccaaccgagagaccagcagcttcagttaccgggaagac
cccgtggtctatgaaattcacccaaccaaatcctttattagtggtgggagcacaataaca
ggtgttggaaaaaatctgaattcggttagcgtcccaaggctggtaattaatgtgcatgaa
gcaggaaggaactatacagtggcatgtcagcatcgctcaaattcagagataatctgctgc
accactccctcactgcaacagctgaatctgcaactccccctgaagaccaaagccttgttc
atgttagacgggatcctttccaaatactttgatctcatttatgtacataatcctgtgttt
aagccttttgaaaagccagtgatgatctcaatgggtaatgaaaatgtactagaaattaag
ggaaatgatattgaccctgaagcagttaaaggtgaagtgttaaaagttggaaataagagc
tgtgagaatatacgctcacattctgaagccattttatgtacggtccccaatgacctgctg
aaattgaacagcgagctaaatatagagtggaagcaagccgtcacttcaaccgtccttgga
aaagtcatagttcaaccagatcagaatttcacaggactggttgttggtgtcgtctccata
tcaataattctcttattattattcgggcttttcctgtggctgaaaaagagaaagcaaatt
aaagatcttggcagtgacttggttcgatatgatgcaagagtccacactccacatttggat
aggcttgtaagtgcccggagtgtgagtccaactgcagaaatggtttcaaatgaatctgtg
gactaccgagctacttttccagaagaccagtttcctaactcatctcagaatggatcatgc
agacaagggcagtatcctctgacggacctgtcccccatcctaactagtggggactctgac
atatccagtccattacttcaaaatacggtccacattgacctcagtgctctaaatccagag
ctggtccaggcagttcagcacgtagtgattgggcccagtagcctgattgtgcatttcaat
gaagtcataggaagagggcattttggctgtgtatatcatggaactttgttggacaatgat
ggcaagaaaattcactgtgctgtaaaatctttgaatagaatcactgacataggagaagtt
tcccagtttttgaccgaggggataatcatgaaagattttagccatcccaatgttctctca
ctcttgggaatctgccttcggagtgaagggtctcccctggtggtcctaccatatatgaag
catggagatctgcgaaatttcattcgaaatgagactcataatccaactgtaaaagatctt
ataggctttggtcttcaagtagccaaaggcatgaaatatcttgcaagcaaaaagtttgtc
cacagagacttggctgcaagaaactgtatgctggatgaaaaattcactgtcaaggtcgct
gattttggtcttgccagggatatgtatgacaaagaatactacagcgtacacaacaaaaca
ggcgcgaaactgccagtgaagtggatggctttagaaagtctgcaaactcagaagttcacc
accaaatcagatgtgtggtcctttggtgtgcttctctgggagctgatgacaaggggagcc
ccaccttatcccgatgtgaacacctttgatatcaccgtgtacctgttgcagggtagaagg
ctcttacaacctgagtactgcccagatcccttatatgaagtgatgcttaaatgttggcac
cccaaagcggaaatgcgcccatccttctctgagctggtctccaggatatctgccatcttt
tccactttcatcggagagcactatgtccatgtgaacgctacctatgtgaatgtaaagtgt
gttgctccatatccttctctcttgtcatcacaagataacgtcgatggtgtggtggacaca
tga

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