Sciurus carolinensis (gray squirrel): 124993425
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Entry
124993425 CDS
T08117
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
ncar
Sciurus carolinensis (gray squirrel)
Pathway
ncar00230
Purine metabolism
ncar00670
One carbon pool by folate
ncar01100
Metabolic pathways
ncar01523
Antifolate resistance
Module
ncar_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ncar00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
124993425
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
124993425
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
124993425
Enzymes [BR:
ncar01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
124993425
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
124993425
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
124993425
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_4
ATP-grasp_3
ATP-grasp_2
Dala_Dala_lig_C
LUD_dom
Sacchrp_dh_NADP
RimK
Motif
Other DBs
NCBI-GeneID:
124993425
NCBI-ProteinID:
XP_047421207
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All DBs
Position
9:complement(130964095..130990937)
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AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGAREHTLAWKLAQSHHVQQVLVAPGNAGTACSEKISNTAISISDHTALTQ
FCKDEKIEFVVVGPEAPLAAGIVGDLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHRIP
TAQWSAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
GVAGETIVVEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPTP
QVSKDLLLKIKNTVLQRTVDGMQQEGTPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQATLDGLLCTSLPIWLENHTAITVVMASKGYPGAYTKGVEITGLSDA
KALGLEVFHAGTTLKDGKVVTSGGRVLTVTAIQENLTSALEEAKKGLTAIKFEGAIYRKD
IGFRAIAFLQQPRGLTYKGSGVDIAAGNMLVTKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTVGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLNMSEAVIAGIATACGQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLEKITEGDVIVGVASSGLHSNGYSLVRKIVAKSSLQYSSPAPDGCGDQSLGDLLLTPTK
IYSRSLLPIIRSGHVKAFAHITGGGLLENIPRVLPQKLGVDLDAQTWKIPRVFSWLQREG
QLSEEEMARTFNCGIGAVLVVSKDQTGQILGDIQQCQEEAWVIGSVVACPEGSPRVKIKN
LLETMQVSKSVSVNGSLKNHFSAQPKKARVAVLISGTGSNLQALIDSTQDPKSHAHIVVV
ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDQVLEEFSTDIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGSNAHEQALEAGVTITGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVATLSERVKSAEHKIFPAALQLVASGTVQLGENGKICWVKEK
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtcattggcagtggcgcgagggaacatacactggcctggaag
cttgcacagtctcatcatgtccaacaagtgcttgttgccccaggaaacgcaggcactgcc
tgctcagaaaagatttcaaatactgccatctccatcagtgatcatactgccctgactcaa
ttctgcaaagatgagaaaattgaatttgtagttgttggaccagaggcacctctggctgca
ggaattgttggggacctcacctctgcaggagtgcgatgcttcggccccacagcagaagca
gctcagttagagtccagcaaaagatttgccaaagagtttatggatcgacacagaatccca
actgcacaatggagcgctttcaccaaacccgaagaggcctgtagcttcattatgagtgca
gacttccctgctttggtcgtgaaggccagtggtcttgcagctgggaaaggggtgattgtt
gcaaagagcaaagaggaagcctgcaaagctgtacaggagatcatgcaggagaaagccttt
ggagtagctggagaaacaattgttgttgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgtttcactgatgggaggacagtggcccccatgcccccagcacaggatcataagcga
ttactggagggagatcaaggccccaacacagggggaatgggagcctattgtcccacacct
caggtttctaaggatttgttactaaaaattaaaaatactgtccttcagaggacagtagat
ggcatgcagcaggagggtactccatacacaggaattctttatgctggtataatgctgacc
aaggatggtccaaaagttttggaatttaattgccgttttggtgatccagagtgccaagta
atcctcccacttcttaaaagtgatctttatgaagtgattcaggccaccttagatggcctg
ctgtgcacatctttacccatttggctagaaaaccacactgcaataactgtcgtcatggca
agtaaaggttatcctggagcctacaccaagggtgtggagataacagggctttctgatgct
aaagctttaggactagaggtgttccatgcaggcactaccctcaaagatggcaaagtggtg
accagcgggggtagagtccttacagtaacagccattcaagaaaacctcacatcggccctt
gaagaagccaagaagggactcactgctataaagtttgagggagcaatttataggaaagac
atcggctttcgcgccatagctttcctccagcagcccaggggcctgacttacaagggatct
ggggtagacattgcagctggaaatatgctggttacaaaaataaagcctttagcaaaagcc
acctccagaccagggtgtgatgtagatcttggaggtttcgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttctggcctctggaacagatggtgttggaactaaactg
aagattgcccagctgtgcaataaacatgatacagttggtcaagatttggttgcaatgtgt
gtaaatgacatcctggcacaaggagcagagcctctcttcttccttgattacttctcctgt
ggaaagcttgaccttaatatgtctgaagccgtcattgccggaattgctacagcttgtgga
caggctggatgtgctctccttggaggtgaaacagcagaaatgcctgacatgtatcctcct
ggagagtacgacctagctggttttgctgttggtgctatggagcgggatcagaaactgcct
cacctggaaaagatcactgaaggggatgttattgttggagtagcttcatctggtcttcac
agcaatggatatagccttgtgaggaaaattgtggcaaagtcttccctgcagtactcctct
ccagcacctgatggttgtggtgaccagtccttaggggacttacttctaactccaaccaaa
atctacagccgttctctgttacccatcatacgttcaggacacgtcaaagcctttgctcat
attactggtggaggactactggaaaacattcctagagttctccctcagaaacttggggtg
gatttagatgcccagacctggaagatccccagggtcttctcatggttacagcgggaagga
cagctctctgaagaagagatggccagaacattcaactgtgggattggagctgtccttgtg
gtatcaaaggatcagacagggcagattctgggtgatattcaacagtgccaagaagaagcc
tgggtgattggcagtgtggttgcatgtcccgaaggttctcctcgtgtgaaaatcaagaat
ctgcttgaaaccatgcaagtgagcaagtcagtgtcagtgaatggctccttgaaaaatcat
ttctctgcccaaccgaaaaaggcaagagtggccgtcttaatatctggaacaggatccaac
ctccaggcactcatagacagtactcaggatccaaagagccacgcacacattgttgttgtt
atctccaacaaagcagcagtggctgggttagataaggcggaaagagctggtatcccaacc
agagtaattaatcataagttatataaaaatcgggttgaatttgacagtgcaattgaccaa
gtccttgaagagttctccacagacatagtctgtcttgcaggattcatgagaattctctct
ggcccctttgtcagaaaatgggatggaaaaatgctgaacatccacccatccttactccct
tcttttaagggttcaaatgctcatgagcaagccctggaagctggagtcacaattactgga
tgcactgtacactttgtagctgaagatgtagatgctggacaaattattttacaagaagct
gttcctgttaagaggggtgacactgttgcaactttgtctgaaagagtaaaatcagcagaa
cataaaatatttcctgcagccctccaactggtggccagtggtactgtacagcttggagaa
aatggcaagatctgttgggtcaaagaaaaatga
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