KEGG   Sciurus carolinensis (gray squirrel): 124994121
Entry
124994121         CDS       T08117                                 
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
ncar  Sciurus carolinensis (gray squirrel)
Pathway
ncar01522  Endocrine resistance
ncar04010  MAPK signaling pathway
ncar04012  ErbB signaling pathway
ncar04014  Ras signaling pathway
ncar04024  cAMP signaling pathway
ncar04068  FoxO signaling pathway
ncar04071  Sphingolipid signaling pathway
ncar04137  Mitophagy - animal
ncar04140  Autophagy - animal
ncar04141  Protein processing in endoplasmic reticulum
ncar04210  Apoptosis
ncar04215  Apoptosis - multiple species
ncar04217  Necroptosis
ncar04310  Wnt signaling pathway
ncar04380  Osteoclast differentiation
ncar04510  Focal adhesion
ncar04530  Tight junction
ncar04620  Toll-like receptor signaling pathway
ncar04621  NOD-like receptor signaling pathway
ncar04622  RIG-I-like receptor signaling pathway
ncar04625  C-type lectin receptor signaling pathway
ncar04657  IL-17 signaling pathway
ncar04658  Th1 and Th2 cell differentiation
ncar04659  Th17 cell differentiation
ncar04660  T cell receptor signaling pathway
ncar04664  Fc epsilon RI signaling pathway
ncar04668  TNF signaling pathway
ncar04722  Neurotrophin signaling pathway
ncar04723  Retrograde endocannabinoid signaling
ncar04728  Dopaminergic synapse
ncar04750  Inflammatory mediator regulation of TRP channels
ncar04910  Insulin signaling pathway
ncar04912  GnRH signaling pathway
ncar04914  Progesterone-mediated oocyte maturation
ncar04917  Prolactin signaling pathway
ncar04920  Adipocytokine signaling pathway
ncar04926  Relaxin signaling pathway
ncar04930  Type II diabetes mellitus
ncar04931  Insulin resistance
ncar04932  Non-alcoholic fatty liver disease
ncar04933  AGE-RAGE signaling pathway in diabetic complications
ncar04935  Growth hormone synthesis, secretion and action
ncar04936  Alcoholic liver disease
ncar05010  Alzheimer disease
ncar05012  Parkinson disease
ncar05016  Huntington disease
ncar05017  Spinocerebellar ataxia
ncar05020  Prion disease
ncar05022  Pathways of neurodegeneration - multiple diseases
ncar05132  Salmonella infection
ncar05133  Pertussis
ncar05135  Yersinia infection
ncar05142  Chagas disease
ncar05145  Toxoplasmosis
ncar05152  Tuberculosis
ncar05161  Hepatitis B
ncar05162  Measles
ncar05166  Human T-cell leukemia virus 1 infection
ncar05167  Kaposi sarcoma-associated herpesvirus infection
ncar05169  Epstein-Barr virus infection
ncar05170  Human immunodeficiency virus 1 infection
ncar05171  Coronavirus disease - COVID-19
ncar05200  Pathways in cancer
ncar05208  Chemical carcinogenesis - reactive oxygen species
ncar05210  Colorectal cancer
ncar05212  Pancreatic cancer
ncar05231  Choline metabolism in cancer
ncar05415  Diabetic cardiomyopathy
ncar05417  Lipid and atherosclerosis
ncar05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ncar00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    124994121
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    124994121
   04012 ErbB signaling pathway
    124994121
   04014 Ras signaling pathway
    124994121
   04310 Wnt signaling pathway
    124994121
   04668 TNF signaling pathway
    124994121
   04068 FoxO signaling pathway
    124994121
   04071 Sphingolipid signaling pathway
    124994121
   04024 cAMP signaling pathway
    124994121
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    124994121
   04137 Mitophagy - animal
    124994121
  09143 Cell growth and death
   04210 Apoptosis
    124994121
   04215 Apoptosis - multiple species
    124994121
   04217 Necroptosis
    124994121
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    124994121
   04530 Tight junction
    124994121
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    124994121
   04621 NOD-like receptor signaling pathway
    124994121
   04622 RIG-I-like receptor signaling pathway
    124994121
   04625 C-type lectin receptor signaling pathway
    124994121
   04660 T cell receptor signaling pathway
    124994121
   04658 Th1 and Th2 cell differentiation
    124994121
   04659 Th17 cell differentiation
    124994121
   04657 IL-17 signaling pathway
    124994121
   04664 Fc epsilon RI signaling pathway
    124994121
  09152 Endocrine system
   04910 Insulin signaling pathway
    124994121
   04920 Adipocytokine signaling pathway
    124994121
   04912 GnRH signaling pathway
    124994121
   04914 Progesterone-mediated oocyte maturation
    124994121
   04917 Prolactin signaling pathway
    124994121
   04926 Relaxin signaling pathway
    124994121
   04935 Growth hormone synthesis, secretion and action
    124994121
  09156 Nervous system
   04728 Dopaminergic synapse
    124994121
   04723 Retrograde endocannabinoid signaling
    124994121
   04722 Neurotrophin signaling pathway
    124994121
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    124994121
  09158 Development and regeneration
   04380 Osteoclast differentiation
    124994121
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    124994121
   05208 Chemical carcinogenesis - reactive oxygen species
    124994121
   05231 Choline metabolism in cancer
    124994121
  09162 Cancer: specific types
   05210 Colorectal cancer
    124994121
   05212 Pancreatic cancer
    124994121
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    124994121
   05170 Human immunodeficiency virus 1 infection
    124994121
   05161 Hepatitis B
    124994121
   05171 Coronavirus disease - COVID-19
    124994121
   05162 Measles
    124994121
   05167 Kaposi sarcoma-associated herpesvirus infection
    124994121
   05169 Epstein-Barr virus infection
    124994121
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    124994121
   05135 Yersinia infection
    124994121
   05133 Pertussis
    124994121
   05152 Tuberculosis
    124994121
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    124994121
   05142 Chagas disease
    124994121
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    124994121
   05012 Parkinson disease
    124994121
   05016 Huntington disease
    124994121
   05017 Spinocerebellar ataxia
    124994121
   05020 Prion disease
    124994121
   05022 Pathways of neurodegeneration - multiple diseases
    124994121
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    124994121
   05418 Fluid shear stress and atherosclerosis
    124994121
   05415 Diabetic cardiomyopathy
    124994121
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    124994121
   04936 Alcoholic liver disease
    124994121
   04932 Non-alcoholic fatty liver disease
    124994121
   04931 Insulin resistance
    124994121
   04933 AGE-RAGE signaling pathway in diabetic complications
    124994121
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    124994121
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ncar01001]
    124994121
Enzymes [BR:ncar01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     124994121
Protein kinases [BR:ncar01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   124994121
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 124994121
NCBI-ProteinID: XP_047421830
LinkDB
Position
10:69695611..70303002
AA seq 464 aa
MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccatttcttatactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggatttgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagtggacaaccagttctacagtgtggaagtgggagactcaaccttcacggtt
ctcaagcgctaccagaatttaaagcctattggctctggggctcagggaatagtttgtgct
gcatatgatgctgtccttgacagaaatgtggccattaagaagctcagcagaccatttcag
aaccaaacacatgccaagagagcttaccgggagctggtcctcatgaagtgtgtgaaccat
aaaaacattattagtttattaaatgtcttcacaccccagaaaacgctggaggagttccaa
gatgtttacttagtaatggaactgatggatgccaacttgtgtcaggtgattcagatggaa
ttagaccatgagcgaatgtcttacctgctataccaaatgttgtgtggcatcaagcatctc
cactctgctggaataattcacagggatttaaaaccaagtaacattgtagtaaagtctgat
tgcacattgaaaatccttgactttggactggccaggacagcaggcacgagcttcatgatg
accccatatgtggtgacacgttattacagagcccctgaggtcatcctgggaatgggctac
aaggagaacgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaataaggtaattgagcaactagga
acaccttgcccggaattcatgaagaaattgcaacccacagtaagaaactatgtggagaat
cggcccaagtatgcaggactcaccttccccaagctctttccagattccctcttcccagcg
gactcagagcacaataaacttaaagccagccaagccagggacttgttgtcaaagatgcta
gtgattgacccagccaagaggatatcagtagatgatgccttacagcacccttacatcaat
gtctggtacgaccctgctgaagtggaggcgcctccacctcagatatatgacaaacagctg
gatgaaagagagcacaccattgaagaatggaaagaacttatttacaaggaagtaatgaat
tcagaagaaaagactaaaaacggcgtagtaaaaggacagccttctccttcaggtgcagca
gtgaacagcagtgagagtctccctccatcctcgtctgtcaatgacatctcctccatgtcc
accgaccagaccctggcatctgacactgacagcagcctggaagcctcggcgggacccctg
ggttgttgcaggtga

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