KEGG   Neisseria canis: NCTC10296_00710
Entry
NCTC10296_00710   CDS       T06799                                 
Symbol
cysG
Name
(GenBank) siroheme synthase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
nci  Neisseria canis
Pathway
nci00860  Porphyrin metabolism
nci01100  Metabolic pathways
nci01110  Biosynthesis of secondary metabolites
nci01120  Microbial metabolism in diverse environments
nci01240  Biosynthesis of cofactors
Module
nci_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:nci00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    NCTC10296_00710 (cysG)
Enzymes [BR:nci01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     NCTC10296_00710 (cysG)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     NCTC10296_00710 (cysG)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     NCTC10296_00710 (cysG)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M Shikimate_DH Yop-YscD_cpl
Other DBs
NCBI-ProteinID: VEF00150
UniProt: A0A448D6S6
LinkDB
Position
1:725251..726699
AA seq 482 aa
MNYLPLFADLTGRHVLVVGGGAVAERKVEMLLKAGAEVGLVAEKLNPALAELAGQRRIEW
LDTKFQPSRLDAVWLVIAATDNHELNRQVSEAAESRRIWANVVDERDACSFIFPSVVNRN
PIQIAISSGGTAPVLARLLREKLEALLPQNLGAMAETAARWRGRVKAKLPSIAQRRRFWE
TLFTHPAFLRLSESSQTSAAEEFLSQQLNGAQTGSGEVSLVGAGPGDAGLLTLKGLQRIQ
QADVVLYDALVSDQVLELIRRDAEKVFVGKRAGKHSVMQEATNRLLVDYAKKGKRVVRLK
GGDPFVFGRGGEELEALKAEGIAFEVVPGITAALGATAYAGIPLTHRDHAQTAMFITGHC
RAGSDDLAWQTIAQSNQTLVVYMGTIKAAELQTNLIAHGRSADTPVAVISKGTLPDQQVF
SGKLNDLAVLAAQAPSPALLVIGETAGLGSDLAWFGGAPQQFVDTRNALWQVPEERALPK
AG
NT seq 1449 nt   +upstreamnt  +downstreamnt
atgaattacctacctttattcgcagatttaaccggccggcatgttttggttgtgggcggc
ggagccgttgcagagcgtaaagtggaaatgttgctcaaagccggtgccgaagtcgggctg
gtggccgaaaagcttaatcctgctttggcggagctggccgggcagcggcgaatcgaatgg
ctggacaccaagtttcagccaagccggttggatgccgtttggctggtgattgccgccacc
gataaccacgagcttaaccggcaggtatccgaagccgccgaaagccgccggatttgggcg
aatgtggtggacgagcgcgatgcctgctcgtttatctttccttccgttgtcaatcgcaat
cctattcaaattgccatttccagcggcggcaccgcgcctgttttggcacgcctgctgcgc
gaaaaattggaagcgctgttgccgcaaaacctgggtgcgatggcggaaaccgccgcccgc
tggcgcgggcgcgtaaaagccaagctgccttccattgcacagcgccgccgcttttgggaa
accttatttacacatcctgcatttttacggttgagcgaaagcagccaaacatctgctgcc
gaagagtttttgtcgcagcagttaaacggtgcgcaaacaggctcgggagaagtgtctctt
gtgggcgcaggcccgggtgatgcgggattgctcacgctcaaaggcttgcagcgcatccag
caggccgatgtggtgttatacgatgctttggtttccgatcaagtgttggagcttatccgc
cgcgatgcggaaaaagtgtttgtcggtaagcgcgccggcaagcacagcgtcatgcaggag
gcaaccaaccgtttgttggtcgattatgcgaaaaaaggcaaacgcgtcgtgcgtttgaaa
ggcggtgatccttttgtgttcggccgcggcggggaagaattggaagcgttgaaggccgag
gggattgcgtttgaagtggtgcccggaatcaccgcggctttgggcgccaccgcttatgcc
ggtattccgctcacgcaccgcgaccatgcgcaaacggcgatgttcattaccggccattgc
cgcgccggcagcgatgacttggcatggcaaaccattgcacaaagcaaccagacgctggtg
gtttatatgggcacgattaaggccgccgaattgcaaaccaatctgattgcccacggcagg
agcgcagacacgccggttgccgtaatcagcaaaggaaccttgcccgaccagcaggttttt
tccggcaagttgaacgatttggccgttttggccgcccaagcgccttcgccggctttgttg
gtaatcggcgaaacggcggggctgggcagcgatttggcgtggttcggcggcgcaccgcag
caatttgtcgatacccgaaacgcattgtggcaggttccagaagaacgagccttgccaaag
gcaggttga

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