Neisseria canis: NCTC10296_02007
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Entry
NCTC10296_02007 CDS
T06799
Symbol
folC
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
nci
Neisseria canis
Pathway
nci00790
Folate biosynthesis
nci01100
Metabolic pathways
nci01240
Biosynthesis of cofactors
Module
nci_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
nci00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
NCTC10296_02007 (folC)
Enzymes [BR:
nci01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
NCTC10296_02007 (folC)
6.3.2.17 tetrahydrofolate synthase
NCTC10296_02007 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
SIS_2
Motif
Other DBs
NCBI-ProteinID:
VEF02844
UniProt:
A0A448DA72
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Position
1:complement(2089375..2090658)
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AA seq
427 aa
AA seq
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MKKNLNDWLSHLETAHSAGLIDMGLSRVGEVKNTMHLNPQCPVIVVAGTNGKGSVCAFLS
QIYKEAGFKTGTLTSPHLLKFNERICVNTQPVSDEEIVAAFERIEAARGDISLTYFEFNT
LAAVDIFMRSQVDVMILEVGLGGRLDAVNIFDADVSVVTSIDLDHQSFLGDTIEQVGYEK
AGVFRSGKPAICGQNPPPESLRKHAEAIGADLLLIGEDFSYTKLENQQWSYRFHPNPQFS
DRHTRNRNALPIPALRGAYQINNAACALTVIECLNQQLPIDIGAIKRGLLMVHNPGRFQV
LPGRPLTVLDVGHNPHAARALRQGLMALPFAQNRTAVFSMLNDKDIDSVLAILKDQFDEW
HIAPLHLPRGMASEQLAEKLAAHDISNVKQFENIAKAYDAAFAAASENDRIVVFGSFHTV
AEVMGTL
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaaaaatctgaacgactggctctcccatttagaaaccgcccacagcgcgggtttg
attgatatgggtctatcccgtgtgggcgaagtgaaaaacaccatgcacctgaacccgcaa
tgcccggtaatcgttgtggcgggcaccaacggcaaaggttcggtgtgtgcatttttatcg
cagatatataaagaagccggcttcaaaaccggcacgctgaccagcccgcatctgttgaaa
ttcaacgagcgtatttgtgtcaacacacagcctgtgtcagatgaagaaatcgtggccgcg
tttgagcgcattgaagccgcgcgtggcgatatttccctcacttattttgagttcaacacg
ctggccgccgtggatattttcatgcggagccaagtggatgtgatgatattggaagtcggg
ctgggcggccgtttggatgctgtaaacatatttgacgccgatgtatccgtggtaaccagc
attgatttagaccaccaatctttccttggcgacaccatcgagcaggtgggctacgaaaaa
gccggtgtgttccgcagcggcaaacccgctatttgcggccagaatccgccgcccgaatcg
ctgagaaaacatgctgaagccataggcgcggatttattgctgatcggagaagatttcagc
tataccaagctggaaaaccagcaatggtcataccgttttcatcctaatccgcagttttca
gacaggcatacgcgcaaccgcaacgctctgccgattcccgccttgcgcggcgcataccaa
atcaacaatgccgcctgtgcgctgaccgttatcgaatgcctcaaccaacaattgccgata
gacataggcgctatcaagcgcggtttgttgatggtgcataatccgggccgtttccaagtt
ttacccggcaggccgctgaccgttttggatgtgggccataatccgcacgcagcccgtgcg
ctgcgtcaggggctgatggccttgccctttgctcaaaaccgtacggccgtgttcagcatg
ttgaacgataaagacatcgattcggttttggcaatcctgaaagaccagtttgacgaatgg
catatcgcgcctctgcatctgccgcgcggcatggcttccgagcagcttgccgaaaaactg
gctgctcacgatataagcaatgtaaaacagtttgaaaatatagcaaaagcttatgatgcg
gcttttgcggcggcttcggaaaatgatagaattgtcgtgttcggctccttccatacggtt
gccgaagttatgggaacactataa
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